John V. Heymach
1991–2026 年に発表
- 別表記
- John V Heymach
- 384
- 論文数
- 60,773
- 被引用数
- 130
- h 指数
- 354
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine58.8%
- Biochemistry, Genetics and Molecular Biology29.1%
- Immunology and Microbiology6%
- Neuroscience1.2%
- Computer Science1.2%
- Engineering0.9%
- その他2.8%
トピック
- Cancer Immunotherapy and Biomarkers7.5%
- Lung Cancer Treatments and Mutations7.3%
- Lung Cancer Research Studies4.5%
- Cancer Genomics and Diagnostics3.9%
- Lung Cancer Diagnosis and Treatment3%
- Immunotherapy and Immune Responses2.3%
- その他71.5%
共著者
- Jianjun Zhang86
- Don L. Gibbons84
- Ignacio I. Wistuba79
- Lauren A. Byers74
- Jing Wang61
- Stephen G. Swisher61
- J. Jack Lee60
- Xiuning Le59
- Tina Cascone55
- Lixia Diao47
- Boris Sepesi46
- Ara A. Vaporciyan42
- Carmen Behrens42
- Ferdinandos Skoulidis40
- Mehmet Altan40
- Monique B. Nilsson40
- Hai T. Tran38
- Marcelo V. Negrão36
- Junya Fujimoto35
- Yasir Y. Elamin35
- Edwin R. Parra34
- John D. Minna34
- Lingzhi Hong33
- Jack A. Roth32
全論文
- Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
著者: Carl M. Gay, C. Allison Stewart, Elizabeth M. Park, Lixia Diao, Sarah M. Groves, Simon Heeke, Barzin Y. Nabet, Junya Fujimoto, Luisa M. Solis, Wei Lü, Yuanxin Xi, Robert J. Cardnell, Qi Wang, Giulia Fabbri, Kasey R. Cargill, Natalie I. Vokes, Kavya Ramkumar, Bingnan Zhang, Carminia Maria Della Corte, Paul Robson, Stephen G. Swisher, Jack A. Roth, Bonnie S. Glisson, David S. Shames, Ignacio I. Wistuba, Jing Wang, Vito Quaranta, John D. Minna, John V. Heymach, Lauren A. Byers - Cancer Cell 2021 被引用: 932
- Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
著者: Charles M. Rudin, John T. Poirier, Lauren A. Byers, Caroline Dive, Afshin Dowlati, Julie George, John V. Heymach, Jane E. Johnson, Jonathan M. Lehman, David MacPherson, Pierre P. Massion, John D. Minna, Trudy G. Oliver, Vito Quaranta, Julien Sage, Roman K. Thomas, Christopher R. Vakoc, Adi F. Gazdar - Nature reviews. Cancer 2019 被引用: 1,275
- STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
著者: Ferdinandos Skoulidis, Michael E. Goldberg, Danielle Greenawalt, Matthew D. Hellmann, Mark M. Awad, Justin F. Gainor, Alexa B. Schrock, Ryan J. Hartmaier, Sally E. Trabucco, Laurie M. Gay, Siraj M. Ali, Julia A. Elvin, Gaurav Singal, Jeffrey S. Ross, David Fabrizio, Péter M. Szabó, Chang Han, Ariella Sasson, Sujaya Srinivasan, Stefan Kirov, Joseph D. Szustakowski, Patrik Vitazka, Robin Edwards, José A. Bufill, Neelesh Sharma, Sai‐Hong Ignatius Ou, Nir Peled, David R. Spigel, Hira Rizvi, Elizabeth Jiménez Aguilar, Brett W. Carter, Jeremy Erasmus, Darragh Halpenny, Andrew J. Plodkowski, Niamh M. Long, Mizuki Nishino, Warren L. Denning, Ana Galán‐Cobo, Haïfa Hamdi, Taghreed Hirz, Pan Tong, Jing Wang, Jaime Rodriguez‐Canales, Pamela Villalobos, Edwin R. Parra, Neda Kalhor, Lynette M. Sholl, Jennifer L. Sauter, Achim A. Jungbluth, Mari Mino–Kenudson, Roxana Azimi, Yasir Y. Elamin, Jianjun Zhang, Giulia C. Leonardi, Fei Jiang, Kwok‐Kin Wong, J. Jack Lee, Vassiliki A. Papadimitrakopoulou, Ignacio I. Wistuba, Vincent A. Miller, Garrett M. Frampton, Jedd D. Wolchok, Alice T. Shaw, Pasi A. Jänne, Philip J. Stephens, Charles M. Rudin, William J. Geese, Lee A. Albacker, John V. Heymach - Cancer Discovery 2018 被引用: 1,604
- Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer
著者: John V. Heymach, David H. Harpole, Tetsuya Mitsudomi, Janis M. Taube, Gabriella Gálffy, Maximilian J. Hochmair, Thomas Winder, Р. А. Зуков, Gabriel Garbaos, Shugeng Gao, Hiroaki Kuroda, Gyula Ostoros, Tho V. Tran, Jian You, Kang‐Yun Lee, Lorenzo Antonuzzo, Zsolt Pápai-Székely, Hiroaki Akamatsu, Bivas Biswas, Alexander I. Spira, Jeffrey Crawford, Ha Le, Mike Aperghis, Gary J. Doherty, Helen Mann, Tamer M. Fouad, Martin Reck - New England Journal of Medicine 2023 被引用: 682
- Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
著者: Yanshuo Chu, Enyu Dai, Yating Li, Guangchun Han, Guangsheng Pei, Davis R. Ingram, Krupa Thakkar, Jiang‐Jiang Qin, Minghao Dang, Xiuning Le, Can Hu, Qing Deng, Ansam Sinjab, Pravesh Gupta, Ruiping Wang, Dapeng Hao, Fuduan Peng, Xinmiao Yan, Yunhe Liu, Shumei Song, Shaojun Zhang, John V. Heymach, Alexandre Reuben, Yasir Y. Elamin, Melissa Pool Pizzi, Yang Lü, Rossana Lazcano, Jian Hu, Mingyao Li, Michael A. Curran, P. Andrew Futreal, Anirban Maitra, Amir A. Jazaeri, Jaffer A. Ajani, Charles Swanton, Xiangdong Cheng, Hussein A. Abbas, Maura L. Gillison, Krishna Bhat, Alexander J. Lazar, Michael R. Green, Kevin Litchfield, Humam Kadara, Cassian Yee, Linghua Wang - Nature Medicine 2023 被引用: 485
- Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer
著者: Triparna Sen, B. Leticia Rodriguez, Limo Chen, Carminia Maria Della Corte, Naoto Morikawa, Junya Fujimoto, Sandra Cristea, Thuyen Nguyen, Lixia Diao, Lerong Li, You-Hong Fan, Yongbin Yang, Jing Wang, Bonnie S. Glisson, Ignacio I. Wistuba, Julien Sage, John V. Heymach, Don L. Gibbons, Lauren A. Byers - Cancer Discovery 2019 被引用: 881
- Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy
著者: Sonia Patel, Monique B. Nilsson, Xiuning Le, Tina Cascone, Rakesh K. Jain, John V. Heymach - Clinical Cancer Research 2022 被引用: 444
- Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy
著者: Ferdinandos Skoulidis, John V. Heymach - Nature reviews. Cancer 2019 被引用: 1,006
- Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations
著者: Paul K. Paik, Enriqueta Felip, Rémi Veillon, Hiroshi Sakai, Alexis B. Cortot, Marina Chiara Garassino, Julien Mazières, Santiago Viteri, Hélène Senellart, Jan P. van Meerbeeck, Jo Raskin, Niels Reinmuth, PierFranco Conte, Dariusz M. Kowalski, Byoung Chul Cho, Jyoti D. Patel, Leora Horn, Frank Griesinger, Ji‐Youn Han, Young‐Chul Kim, Gee‐Chen Chang, Chen‐Liang Tsai, James Chih‐Hsin Yang, Yuh-Min Chen, Egbert F. Smit, Anthonie J. van der Wekken, Terufumi Kato, Dilafruz Juraeva, Christopher Stroh, Rolf Bruns, Josef Straub, Andreas Johne, J. Scheele, John V. Heymach, Xiuning Le - New England Journal of Medicine 2020 被引用: 854
- Deep learning-based prediction of the T cell receptor-antigen binding specificity
著者: Tianshi Lu, Ze Zhang, James Zhu, Yunguan Wang, Peixin Jiang, Xue Xiao, Chantale Bernatchez, John V. Heymach, Don L. Gibbons, Jun Wang, Lin Xu, Alexandre Reuben, Tao Wang - Nature Machine Intelligence, Nat. Mach. Intell. 2021 被引用: 294
- Co-occurring Genomic Alterations Define Major Subsets of KRAS -Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities
著者: Ferdinandos Skoulidis, Lauren A. Byers, Lixia Diao, Vassiliki A. Papadimitrakopoulou, Pan Tong, Julie Izzo, Carmen Behrens, Humam Kadara, Edwin R. Parra, Jaime Rodriguez Canales, Jianjun Zhang, Uma Giri, Jayanthi Gudikote, María Angélica Cortez, Chao Yang, You-Hong Fan, Michael Peyton, Luc Girard, Kevin R. Coombes, Carlo Toniatti, Timothy P. Heffernan, Murim Choi, Garrett M. Frampton, Vincent A. Miller, John N. Weinstein, Roy S. Herbst, Kwok‐Kin Wong, Jianhua Zhang, Padmanee Sharma, Gordon B. Mills, Waun Ki Hong, John D. Minna, James P. Allison, P. Andrew Futreal, Jing Wang, Ignacio I. Wistuba, John V. Heymach - Cancer Discovery 2015 被引用: 916
- Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status
著者: Biagio Ricciuti, Kathryn C. Arbour, W. Marston Linehan, Amir Vajdi, Natalie I. Vokes, Lingzhi Hong, Jianjun Zhang, Michael Tolstorukov, Yvonne Y. Li, Liam F. Spurr, Andrew D. Cherniack, Gonzalo Recondo, Giuseppe Lamberti, Xinan Wang, Deepti Venkatraman, Joao V. Alessi, Victor R. Vaz, Hira Rizvi, Jacklynn V. Egger, Andrew J. Plodkowski, S. Khosrowjerdi, Subba R. Digumarthy, Hyesun Park, Nuno Vaz, Mizuki Nishino, Lynette M. Sholl, David A. Barbie, Mehmet Altan, John V. Heymach, Ferdinandos Skoulidis, Justin F. Gainor, Matthew D. Hellmann, Mark M. Awad - Journal of Thoracic Oncology 2021 被引用: 367
- Structure-based classification predicts drug response in EGFR-mutant NSCLC
著者: Jacqulyne Robichaux, Xiuning Le, R. S. K. Vijayan, J. Kevin Hicks, Simon Heeke, Yasir Y. Elamin, Heather Lin, Hibiki Udagawa, Ferdinandos Skoulidis, Hai T. Tran, Susan Varghese, Junqin He, Fahao Zhang, Monique B. Nilsson, Lemei Hu, Alissa Poteete, Waree Rinsurongkawong, Xiaoshan Zhang, Chenghui Ren, Xiaoke Liu, Lingzhi Hong, Jianjun Zhang, Lixia Diao, Russell W. Madison, Alexa B. Schrock, Jennifer Saam, Victoria M. Raymond, Bingliang Fang, Jing Wang, Min Jin Ha, Jason B. Cross, Jhanelle E. Gray, John V. Heymach - Nature 2021 被引用: 452
- AI in drug discovery and its clinical relevance
著者: Rizwan Qureshi, Muhammad Irfan, Taimoor Muzaffar Gondal, Sheheryar Khan, Jia Wu, Muhammad Usman Hadi, John V. Heymach, Xiuning Le, Hong Yan, Tanvir Alam - Heliyon 2023 被引用: 272
- Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non–Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study
著者: Daniel R. Gomez, Chad Tang, Jianjun Zhang, George R. Blumenschein, Mike Hernández, J. Jack Lee, Rong Ye, David A. Palma, Alexander V. Louie, D. Ross Camidge, Robert C. Doebele, Ferdinandos Skoulidis, Laurie E. Gaspar, James W. Welsh, Don L. Gibbons, José A. Karam, Brian D. Kavanagh, Anne S. Tsao, Boris Sepesi, Stephen G. Swisher, John V. Heymach - Journal of Clinical Oncology 2019 被引用: 1,270
- Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy
著者: Tina Cascone, Jodi A. McKenzie, Rina M. Mbofung, Simone Punt, Zhe Wang, Chunyu Xu, Leila J. Williams, Zhiqiang Wang, Christopher A. Bristow, Alessandro Carugo, Michael Peoples, Lerong Li, Tatiana V. Karpinets, Lu Huang, Shruti Malu, Caitlin Creasy, Sara Elizabeth Leahey, Jiong Chen, Yuan Chen, Helen Pelicano, Chantale Bernatchez, Y.N. Vashisht Gopal, Timothy P. Heffernan, Jianhua Hu, Jing Wang, Rodabe N. Amaria, Levi A. Garraway, Peng Huang, Peiying Yang, Ignacio I. Wistuba, Scott E. Woodman, Jason Roszik, R. Eric Davis, Michael A. Davies, John V. Heymach, Patrick Hwu, Weiyi Peng - Cell Metabolism 2018 被引用: 624
- STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment
著者: Shohei Koyama, Esra A. Akbay, Yvonne Y. Li, Amir Reza Aref, Ferdinandos Skoulidis, Grit S. Herter-Sprie, Kevin A. Buczkowski, Yan Liu, Mark M. Awad, Warren L. Denning, Lixia Diao, Jing Wang, Edwin R. Parra-Cuentas, Ignacio I. Wistuba, Margaret Soucheray, Tran C. Thai, Hajime Asahina, Shunsuke Kitajima, Abigail Altabef, Jillian D. Cavanaugh, Kevin Rhee, Peng Gao, Haikuo Zhang, Peter E. Fecci, Takeshi Shimamura, Matthew D. Hellmann, John V. Heymach, F. Stephen Hodi, Gordon J. Freeman, David A. Barbie, Glenn Dranoff, Peter S. Hammerman, Kwok‐Kin Wong - Cancer Research 2016 被引用: 630
- Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial
著者: Tina Cascone, Cheuk Hong Leung, Annikka Weissferdt, Apar Pataer, Brett W. Carter, Myrna C. B. Godoy, Hope Feldman, William N. William, Yuanxin Xi, Sreyashi Basu, Jing Sun, Shalini S. Yadav, Frank Rojas Alvarez, Younghee Lee, Aditya K. Mishra, Lili Chen, Monika Pradhan, Haiping Guo, Ansam Sinjab, Nicolas Zhou, Marcelo V. Negrão, Xiuning Le, Carl M. Gay, Anne S. Tsao, Lauren A. Byers, Mehmet Altan, Bonnie S. Glisson, Frank V. Fossella, Yasir Y. Elamin, George Blumenschein, Jianjun Zhang, Ferdinandos Skoulidis, Jia Wu, Reza J. Mehran, David C. Rice, Garrett L. Walsh, Wayne L. Hofstetter, Ravi Rajaram, Mara B. Antonoff, Junya Fujimoto, Luisa M. Solis, Edwin R. Parra, Cara Haymaker, Ignacio I. Wistuba, Stephen G. Swisher, Ara A. Vaporciyan, Heather Lin, Jing Wang, Don L. Gibbons, J. Jack Lee, Nadim J. Ajami, Jennifer A. Wargo, James P. Allison, Padmanee Sharma, Humam Kadara, John V. Heymach, Boris Sepesi - Nature Medicine 2023 被引用: 206
- Pembrolizumab with or without radiotherapy for metastatic non-small-cell lung cancer: a pooled analysis of two randomised trials
著者: Willemijn S.M.E. Theelen, Dawei Chen, Vivek Verma, Brian P. Hobbs, Heike Peulen, Joachim G.J.V. Aerts, Idris Bahce, Anna Larissa N. Niemeijer, Joe Y. Chang, Patricia M. de Groot, Quynh-Nhu Nguyen, Nathan Comeaux, George R. Simon, Ferdinandos Skoulidis, Steven H. Lin, Kewen He, Roshal R. Patel, John V. Heymach, Paul Baas, James W. Welsh - The Lancet Respiratory Medicine 2020 被引用: 558
- MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
著者: Yu Qian, Ana Galán‐Cobo, Irene Guijarro, Minghao Dang, David Molkentine, Alissa Poteete, Fahao Zhang, Qi Wang, Jing Wang, Edwin R. Parra, Apekshya Panda, Jacy Fang, Ferdinandos Skoulidis, Ignacio I. Wistuba, Svena Verma, Taha Merghoub, Jedd D. Wolchok, Kwok‐Kin Wong, Ralph J. DeBerardinis, John D. Minna, Natalie I. Vokes, Catherine B. Meador, Justin F. Gainor, Linghua Wang, Alexandre Reuben, John V. Heymach - Cancer Cell 2023 被引用: 178
- Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC
著者: Marcelo V. Negrão, Haniel A. Araújo, Giuseppe Lamberti, Alissa J. Cooper, Neal S. Akhave, Teng Zhou, Lukas Delasos, J. Kevin Hicks, Mihaela Aldea, Gabriele Minuti, Jacobi Hines, Jacqueline V. Aredo, Michael J. Dennis, Turja Chakrabarti, Susan C. Scott, Paolo Bironzo, Matthias Scheffler, Petros Christopoulos, Albrecht Stenzinger, Jonathan W. Riess, So Yeon Kim, Sarah B. Goldberg, Mingjia Li, Qi Wang, Yun Qing, Ying Ni, Minh Truong, Richard Lee, Biagio Ricciuti, Joao V. Alessi, Jing Wang, Blerina Resuli, Lorenza Landi, Shu-Chi Tseng, Mizuki Nishino, Subba R. Digumarthy, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Ara A. Vaporciyan, George R. Blumenschein, Jianjun Zhang, Dwight H. Owen, Collin M. Blakely, Giannis Mountzios, Catherine A. Shu, Christine M. Bestvina, Marina Chiara Garassino, Kristen A. Marrone, Jhanelle E. Gray, Sandip Pravin Patel, Amy L. Cummings, Heather A. Wakelee, Juergen Wolf, Giorgio V. Scagliotti, Federico Cappuzzo, Fabrice Barlési, Pradnya D. Patil, Leylah Drusbosky, Don L. Gibbons, Funda Meric‐Bernstam, J. Jack Lee, John V. Heymach, David S. Hong, Rebecca S. Heist, Mark M. Awad, Ferdinandos Skoulidis - Cancer Discovery 2023 被引用: 181
- Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
著者: Marcelo V. Negrão, Ferdinandos Skoulidis, Meagan Montesion, Katja Schulze, Ilze Bāra, Vincent K. Shen, Hao Xu, Sylvia Hu, Dawen Sui, Yasir Y. Elamin, Xiuning Le, Michael E. Goldberg, Karthikeyan Murugesan, Chang‐Jiun Wu, Jianhua Zhang, Jianhua Zhang, David S Barreto, Jacqulyne Robichaux, Alexandre Reuben, Tina Cascone, Carl M. Gay, K. G. Mitchell, Lingzhi Hong, Waree Rinsurongkawong, Jack A. Roth, Stephen G. Swisher, J. Jack Lee, Anne S. Tsao, Vassiliki A. Papadimitrakopoulou, Don L. Gibbons, Bonnie S. Glisson, Gaurav Singal, Vincent A. Miller, Brian M. Alexander, Garrett M. Frampton, Lee A. Albacker, David S. Shames, Jianjun Zhang, Jianjun Zhang, John V. Heymach - Journal for ImmunoTherapy of Cancer 2021 被引用: 292
- Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer
著者: C. Allison Stewart, Carl M. Gay, Yuanxin Xi, Santhosh Sivajothi, V. Sivakamasundari, Junya Fujimoto, Mohan Bolisetty, Patrice M. Hartsfield, Veerakumar Balasubramaniyan, Milind D. Chalishazar, César A. Moran, Neda Kalhor, John Stewart, Hai T. Tran, Stephen G. Swisher, Jack A. Roth, Jianjun Zhang, John de Groot, Bonnie S. Glisson, Trudy G. Oliver, John V. Heymach, Ignacio I. Wistuba, Paul Robson, Jing Wang, Lauren A. Byers - Nature Cancer 2020 被引用: 372
- Stereotactic ablative radiotherapy with or without immunotherapy for early-stage or isolated lung parenchymal recurrent node-negative non-small-cell lung cancer: an open-label, randomised, phase 2 trial
著者: Joe Y. Chang, Steven H. Lin, Wenli Dong, Zhongxing Liao, Saumil Gandhi, Carl M. Gay, Jianjun Zhang, Stephen G. Chun, Yasir Y. Elamin, Frank V. Fossella, George R. Blumenschein, Tina Cascone, Xiuning Le, J.V. Pozadzides, Anne S. Tsao, Vivek Verma, James W. Welsh, Aileen B. Chen, Mehmet Altan, Reza J. Mehran, Ara A. Vaporciyan, Stephen G. Swisher, Peter Balter, Junya Fujimoto, Ignacio I. Wistuba, Lei Feng, J Jack Lee, John V. Heymach - The Lancet 2023 被引用: 224
