Joseph A. Trapani
1985–2025 年に発表
- 138
- 論文数
- 25,577
- 被引用数
- 91
- h 指数
- 136
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine41.5%
- Immunology and Microbiology26.9%
- Biochemistry, Genetics and Molecular Biology25.7%
- Engineering1.5%
- Neuroscience1.1%
- Nursing1.1%
- その他2.2%
トピック
- Immune Cell Function and Interaction9.8%
- CAR-T cell therapy research7.3%
- Immunotherapy and Immune Responses5.6%
- Cancer Immunotherapy and Biomarkers4.9%
- T-cell and B-cell Immunology4.2%
- Cell death mechanisms and regulation2.9%
- その他65.3%
共著者
- Mark J. Smyth34
- Ilia Voskoboinik28
- Phillip K. Darcy25
- Vivien R. Sutton22
- Paul J. Neeson21
- Ricky W. Johnstone17
- Michael H. Kershaw15
- Kylie A. Browne14
- Phillip I. Bird14
- James C. Whisstock13
- Paul A. Beavis12
- H. Miles Prince9
- Kevin Thia9
- Catherina H. Bird8
- Michelle A. Dunstone8
- David A. Jans7
- Paul G. Ekert7
- Annette Ciccone6
- Helen R. Saibil6
- Ian A. Parish6
- Jane Oliaro6
- Jiuru Sun6
- Karin Sedelies6
- Kelly M. Ramsbottom6
全論文
- Perforin and granzymes: function, dysfunction and human pathology
著者: Ilia Voskoboinik, James C. Whisstock, Joseph A. Trapani - Nature reviews. Immunology 2015 被引用: 1,288
- CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity
著者: Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, Enid Y.N. Lam, Melissa A. Henderson, Charles C. Bell, Sabine Stolzenburg, Omer Gilan, Stuart Bloor, Tahereh Noori, David W. Morgens, Michael C. Bassik, Paul J. Neeson, Andreas Behren, Phillip K. Darcy, Sarah‐Jane Dawson, Ilia Voskoboinik, Joseph A. Trapani, Jonathan Cebon, Paul J. Lehner, Mark A. Dawson - Nature 2017 被引用: 969
- Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
著者: Florida Voli, Emanuele Valli, Luigi Lerra, Kathleen Kimpton, Federica Saletta, Federico M. Giorgi, Daniele Mercatelli, Jourdin R.C. Rouaen, Sylvie Shen, Jayne Murray, Aria Ahmed-Cox, Giuseppe Cirillo, Chelsea Mayoh, Paul A. Beavis, Michelle Haber, Joseph A. Trapani, Maria Kavallaris, Orazio Vittorio - Cancer Research 2020 被引用: 419
- Tumor immune evasion arises through loss of TNF sensitivity
著者: Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg, Kelly M. Ramsbottom, Andrew J. Freeman, Najoua Lalaoui, Lizzy Pijpers, Jessica Michie, Kristin Brown, Deborah A. Knight, Vivien R. Sutton, Paul A. Beavis, Ilia Voskoboinik, Phillip K. Darcy, John Silke, Joseph A. Trapani, Ricky W. Johnstone, Jane Oliaro - Science Immunology 2018 被引用: 393
- Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer
著者: Amélie Cachot, Mariia Bilous, Yen‐Cheng Liu, Xiaokang Li, Margaux Saillard, Mara Cenerenti, Georg Alexander Rockinger, Tania Wyss, Philippe Guillaume, Julien Schmidt, Raphaël Genolet, Giuseppe Ercolano, Maria Pia Protti, Walter Reith, Kalliopi Ioannidou, Laurence de Leval, Joseph A. Trapani, George Coukos, Alexandre Harari, Daniel E. Speiser, Alexander Mathis, David Gfeller, Hatice Altug, Pedro Romero, Camilla Jandus - Science Advances 2021 被引用: 320
- Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity
著者: Alexander J. Davenport, Ryan Cross, Katherine A. Watson, Yi‐Han Liao, W. Shi, H. Miles Prince, Paul A. Beavis, Joseph A. Trapani, Michael H. Kershaw, David Ritchie, Phillip K. Darcy, Paul J. Neeson, Misty R. Jenkins - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 被引用: 357
- Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
著者: Junyun Lai, Sherly Mardiana, Imran G. House, Kevin Sek, Melissa A. Henderson, Lauren Giuffrida, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Jack D. Chan, Emma M. Carrington, Andrew M. Lew, Benjamin Solomon, Joseph A. Trapani, Katherine Kedzierska, Maximilien Evrard, Stephin J. Vervoort, Jason Waithman, Phillip K. Darcy, Paul A. Beavis - Nature Immunology 2020 被引用: 215
- Functional significance of the perforin/granzyme cell death pathway
著者: Joseph A. Trapani, Mark J. Smyth - Nature reviews. Immunology 2002 被引用: 1,247
- Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
著者: Nicolas Jacquelot, Cyril Seillet, Minyu Wang, Angela Pizzolla, Yang Liao, Soroor Hediyeh-zadeh, Sharon Grisaru‐Tal, Cynthia Louis, Qiutong Huang, Jaring Schreuder, Fernando Souza-Fonseca-Guimarães, Carolyn A. de Graaf, Kevin Thia, Sean Macdonald, Mary Camilleri, Kylie Luong, Shengbo Zhang, Michaël Chopin, Tristan Molden-Hauer, Stephen L. Nutt, Viktor Umansky, Bogoljub Ćirić, Joanna R. Groom, Paul S. Foster, Philip M. Hansbro, Andrew N. J. McKenzie, Daniel H.D. Gray, Andreas Behren, Jonathan Cebon, Éric Vivier, Ian P. Wicks, Joseph A. Trapani, Ariel Munitz, Melissa J. Davis, Wei Shi, Paul J. Neeson, Gabrielle T. Belz - Nature Immunology 2021 被引用: 175
- ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack
著者: Alex T. Ritter, Gleb Shtengel, C. Shan Xu, Aubrey V. Weigel, David P. Hoffman, Melanie Freeman, Nirmala Iyer, Nensi Alivodej, David Ackerman, Ilia Voskoboinik, Joseph A. Trapani, Harald F. Hess, Ira Mellman - Science 2022 被引用: 131
- Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells
著者: Mario Witkowski, Caroline Tizian, Marta Ferreira‐Gomes, Daniela Niemeyer, Terry C. Jones, Frederik Heinrich, Stefan Frischbutter, Stefan Angermair, Thordis Hohnstein, Irene Mattiola, Philipp Nawrath, Sophie McEwen, Silvia Zocche, Edoardo Viviano, Gitta Anne Heinz, Marcus Maurer, Uwe Kölsch, Robert Lorenz Chua, Tom Aschman, Christian Meisel, Josefine Radke, Birgit Sawitzki, Jobst Roehmel, Kristina Allers, Verena Moos, Thomas Schneider, Leif G. Hanitsch, Marcus Mall, Christian Conrad, Helena Radbruch, Claudia U. Duerr, Joseph A. Trapani, Emanuela Marcenaro, Tilmann Kallinich, Victor M. Corman, Florian Kurth, Leif Erik Sander, Christian Drosten, Sascha Treskatsch, Pawel Durek, Andrey Kruglov, Andreas Radbruch, Mir‐Farzin Mashreghi, Andreas Diefenbach - Nature 2021 被引用: 280
- T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models
著者: Déborah Meyran, Joe Jiang Zhu, Jeanne Butler, Daniela Tantalo, Sean Macdonald, Thu Ngoc Nguyen, Minyu Wang, Niko Thio, Criselle D’Souza, Vicky Mengfei Qin, Clare Y. Slaney, Aaron J Harrison, Kevin Sek, Pasquale Petrone, Kevin Thia, Lauren Giuffrida, Andrew M. Scott, Rachael Terry, Ben Tran, Jayesh Desai, H. Miles Prince, Simon J. Harrison, Paul A. Beavis, Michael H. Kershaw, Benjamin Solomon, Paul G. Ekert, Joseph A. Trapani, Phillip K. Darcy, Paul J. Neeson - Science Translational Medicine 2023 被引用: 97
- Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia
著者: David S. Ritchie, Paul J. Neeson, Amit Khot, Stefan Peinert, Tsin Yee Tai, Kellie M. Tainton, Karen Chen, Mandy Shin, Dominic Wall, Dirk Hönemann, Peter Gambell, David Westerman, Javier Haurat, Jennifer A. Westwood, Andrew M. Scott, L. Ya. Kravets, Michael Dickinson, Joseph A. Trapani, Mark J. Smyth, Phillip K. Darcy, Michael H. Kershaw, H. Miles Prince - Molecular Therapy 2013 被引用: 433
- Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy
著者: Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida, Jane K. Mills, Kevin Sek, Ryan Cross, Alexander J. Davenport, Liza B. John, Sherly Mardiana, Clare Y. Slaney, Ricky W. Johnstone, Joseph A. Trapani, John Stagg, Sherene Loi, Lev M. Kats, David Gyorki, Michael H. Kershaw, Phillip K. Darcy - Journal of Clinical Investigation 2017 被引用: 321
- Perforin-mediated target-cell death and immune homeostasis
著者: Ilia Voskoboinik, Mark J. Smyth, Joseph A. Trapani - Nature reviews. Immunology 2006 被引用: 590
- Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction
著者: Kenji M. Fujihara, Bonnie Z. Zhang, Thomas D. Jackson, Moses Olalekan Ogunkola, Brunda Nijagal, Julia V. Milne, David A. Sallman, Ching‐Seng Ang, Iva Nikolić, Conor J. Kearney, Simon J. Hogg, Carlos S. Cabalag, Vivien R. Sutton, Sally V. Watt, Asuka T. Fujihara, Joseph A. Trapani, Kaylene J. Simpson, Diana Stojanovski, Silke Leimkühler, Sue Haupt, Wayne A. Phillips, Nicholas J. Clemons - Science Advances 2022 被引用: 94
- CAR-T Cells Inflict Sequential Killing of Multiple Tumor Target Cells
著者: Alexander J. Davenport, Misty R. Jenkins, Ryan Cross, Carmen S. Yong, H. Miles Prince, David S. Ritchie, Joseph A. Trapani, Michael H. Kershaw, Phillip K. Darcy, Paul J. Neeson - Cancer Immunology Research 2015 被引用: 148
- Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies
著者: Simone Nüssing, Imran G. House, Conor J. Kearney, Amanda X. Y. Chen, Stephin J. Vervoort, Paul A. Beavis, Jane Oliaro, Ricky W. Johnstone, Joseph A. Trapani, Ian A. Parish - The Journal of Immunology 2020 被引用: 91
- Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance
著者: Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James Torpy, Deborah A. Knight, Sinead M. Reading, Kevin Thia, Lisa A. Miosge, Debbie Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish - Nature Communications 2021 被引用: 59
- Therapeutic strategies to remodel immunologically cold tumors
著者: Minyu Wang, Sen Wang, Jayesh Desai, Joseph A. Trapani, Paul J. Neeson - Clinical & Translational Immunology 2020 被引用: 80
- Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
著者: Misty R. Jenkins, Jesse A. Rudd-Schmidt, Jamie A. Lopez, Kelly M. Ramsbottom, Stuart I. Mannering, Daniel M. Andrews, Ilia Voskoboinik, Joseph A. Trapani - The Journal of Experimental Medicine 2015 被引用: 254
- Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack
著者: Jamie A. Lopez, Olivia Susanto, Misty R. Jenkins, Natalya Lukoyanova, Vivien R. Sutton, Ruby H. P. Law, Angus P. R. Johnston, Catherina H. Bird, Phillip I. Bird, James C. Whisstock, Joseph A. Trapani, Helen R. Saibil, Ilia Voskoboinik - Blood 2013 被引用: 251
- SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells
著者: Conor J. Kearney, Stephin J. Vervoort, Kelly M. Ramsbottom, Izabela Todorovski, Emily J. Lelliott, Magnus Zethoven, Lizzy Pijpers, Ben P. Martin, Timothy Semple, Luciano G. Martelotto, Joseph A. Trapani, Ian A. Parish, Nichollas E. Scott, Jane Oliaro, Ricky W. Johnstone - Science Advances 2021 被引用: 84
- Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models
著者: L. H. Porter, Joe Jiang Zhu, Natalie L. Lister, Sarah Harrison, Shivakumar Keerthikumar, D. L. Goode, Rosalía Quezada Urban, D.J. Byrne, Arun Azad, Ian Vela, Michael S. Hofman, Paul J. Neeson, Phillip K. Darcy, Joseph A. Trapani, Renea A. Taylor, Gail P. Risbridger - Nature Communications 2023 被引用: 44
