Phillip K. Darcy
1993–2025 年に発表
- 102
- 論文数
- 20,004
- 被引用数
- 78
- h 指数
- 100
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine54.2%
- Biochemistry, Genetics and Molecular Biology21.7%
- Immunology and Microbiology19.6%
- Engineering2.1%
- Neuroscience0.7%
- Computer Science0.5%
- その他1.2%
トピック
- Cancer Immunotherapy and Biomarkers11.2%
- CAR-T cell therapy research11%
- Immune Cell Function and Interaction8.8%
- Immunotherapy and Immune Responses7.9%
- Immune cells in cancer3.9%
- T-cell and B-cell Immunology2.8%
- その他54.4%
共著者
- Michael H. Kershaw42
- Paul A. Beavis33
- Mark J. Smyth29
- Paul J. Neeson26
- Joseph A. Trapani25
- Sherene Loi17
- Clare Y. Slaney14
- Jennifer A. Westwood14
- Melissa A. Henderson13
- Kevin Sek12
- Peter Savas12
- Liza B. John10
- Michele W.L. Teng10
- Bianca von Scheidt9
- Christel Devaud9
- H. Miles Prince9
- Jack D. Chan9
- Lauren Giuffrida9
- Ricky W. Johnstone9
- Sherly Mardiana9
- Amanda J. Oliver8
- Amanda X. Y. Chen8
- John Stagg8
- Junyun Lai8
全論文
- Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade
著者: Imran G. House, Peter Savas, Junyun Lai, Amanda X. Y. Chen, Amanda J. Oliver, Zhi L. Teo, Kirsten L. Todd, Melissa A. Henderson, Lauren Giuffrida, Emma V. Petley, Kevin Sek, Sherly Mardiana, Tuba N. Gide, Camelia Quek, Richard A. Scolyer, Georgina V. Long, James S. Wilmott, Sherene Loi, Phillip K. Darcy, Paul A. Beavis - Clinical Cancer Research 2019 被引用: 766
- Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
著者: Peter Savas, Balaji Virassamy, Chengzhong Ye, Agus Salim, Christopher Mintoff, Franco Caramia, Roberto Salgado, David J. Byrne, Zhi L. Teo, Sathana Dushyanthen, Ann Byrne, Lironne Wein, Stephen J. Luen, Catherine Poliness, Sophie Nightingale, Anita Skandarajah, David Gyorki, Chantel M. Thornton, Paul A. Beavis, Stephen B. Fox, Phillip K. Darcy, Terence P. Speed, Laura K. Mackay, Paul J. Neeson, Sherene Loi - Nature Medicine 2018 被引用: 991
- CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity
著者: Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, Enid Y.N. Lam, Melissa A. Henderson, Charles C. Bell, Sabine Stolzenburg, Omer Gilan, Stuart Bloor, Tahereh Noori, David W. Morgens, Michael C. Bassik, Paul J. Neeson, Andreas Behren, Phillip K. Darcy, Sarah‐Jane Dawson, Ilia Voskoboinik, Joseph A. Trapani, Jonathan Cebon, Paul J. Lehner, Mark A. Dawson - Nature 2017 被引用: 969
- FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
著者: Jack D. Chan, C. Scheffler, Isabelle Munoz, Kevin Sek, Joel N. Lee, Yukuan Huang, Kah Min Yap, Nicole Y. L. Saw, Jasmine Li, Amanda X. Y. Chen, Cheok Weng Chan, Emily B. Derrick, Kirsten L. Todd, Junming Tong, Phoebe Dunbar, Jiawen Li, Thang X. Hoang, Maria N. de Menezes, Emma V. Petley, Joelle S. Kim, Dat Quoc Nguyen, P. Leung, Joan So, Christian Deo T. Deguit, Joe Jiang Zhu, Imran G. House, Lev M. Kats, Andrew M. Scott, Benjamin Solomon, Simon J. Harrison, Jane Oliaro, Ian A. Parish, Kylie M. Quinn, Paul J. Neeson, Clare Y. Slaney, Junyun Lai, Paul A. Beavis, Phillip K. Darcy - Nature 2024 被引用: 214
- Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
著者: Balaji Virassamy, Franco Caramia, Peter Savas, Sneha Sant, Jianan Wang, Susan N. Christo, Ann Byrne, Kylie Clarke, Emmaline Brown, Zhi L. Teo, Bianca von Scheidt, David Freestone, Luke C. Gandolfo, Karsten E. Weber, Julia Teply‐Szymanski, Ran Li, Stephen J. Luen, Carsten Denkert, Sibylle Loibl, Olivia Lucas, Charles Swanton, Terence P. Speed, Phillip K. Darcy, Paul J. Neeson, Laura K. Mackay, Sherene Loi - Cancer Cell 2023 被引用: 221
- Clinical relevance of host immunity in breast cancer: from TILs to the clinic
著者: Peter Savas, Roberto Salgado, Carsten Denkert, Christos Sotiriou, Phillip K. Darcy, Mark J. Smyth, Sherene Loi - Nature Reviews Clinical Oncology 2015 被引用: 904
- Tumor immune evasion arises through loss of TNF sensitivity
著者: Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg, Kelly M. Ramsbottom, Andrew J. Freeman, Najoua Lalaoui, Lizzy Pijpers, Jessica Michie, Kristin Brown, Deborah A. Knight, Vivien R. Sutton, Paul A. Beavis, Ilia Voskoboinik, Phillip K. Darcy, John Silke, Joseph A. Trapani, Ricky W. Johnstone, Jane Oliaro - Science Immunology 2018 被引用: 393
- Cellular networks controlling T cell persistence in adoptive cell therapy
著者: Jack D. Chan, Junyun Lai, Clare Y. Slaney, Axel Kallies, Paul A. Beavis, Phillip K. Darcy - Nature reviews. Immunology 2021 被引用: 235
- CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy
著者: Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Junyun Lai, Amanda X. Y. Chen, Déborah Meyran, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Christina Mølck, Gregory D. Stewart, Benjamin Solomon, Ian A. Parish, Paul J. Neeson, Simon J. Harrison, Lev M. Kats, Imran G. House, Phillip K. Darcy, Paul A. Beavis - Nature Communications 2021 被引用: 210
- Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity
著者: Alexander J. Davenport, Ryan Cross, Katherine A. Watson, Yi‐Han Liao, W. Shi, H. Miles Prince, Paul A. Beavis, Joseph A. Trapani, Michael H. Kershaw, David Ritchie, Phillip K. Darcy, Paul J. Neeson, Misty R. Jenkins - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 被引用: 357
- Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
著者: Junyun Lai, Sherly Mardiana, Imran G. House, Kevin Sek, Melissa A. Henderson, Lauren Giuffrida, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Jack D. Chan, Emma M. Carrington, Andrew M. Lew, Benjamin Solomon, Joseph A. Trapani, Katherine Kedzierska, Maximilien Evrard, Stephin J. Vervoort, Jason Waithman, Phillip K. Darcy, Paul A. Beavis - Nature Immunology 2020 被引用: 215
- Tumor macrophage functional heterogeneity can inform the development of novel cancer therapies
著者: Ibraheem Nasir, Conor McGuinness, Ashleigh R. Poh, Matthias Ernst, Phillip K. Darcy, Kara L. Britt - Trends in Immunology 2023 被引用: 138
- Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape
著者: Leisha A. Emens, Paolo A. Ascierto, Phillip K. Darcy, Sandra Demaria, Alexander M.M. Eggermont, William L. Redmond, Barbara Seliger, Francesco M. Marincola - European Journal of Cancer 2017 被引用: 562
- PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity
著者: Florian Wiede, Kun‐Hui Lu, Xin Du, Mara N. Zeissig, Rachel Xu, Pei Kee Goh, Chrysovalantou E. Xirouchaki, Samuel J. Hogarth, Spencer Greatorex, Kevin Sek, Roger J. Daly, Paul A. Beavis, Phillip K. Darcy, Nicholas K. Tonks, Tony Tiganis - Cancer Discovery 2021 被引用: 137
- Anti-PD-1 Antibody Therapy Potently Enhances the Eradication of Established Tumors By Gene-Modified T Cells
著者: Liza B. John, Christel Devaud, Connie P.M. Duong, Carmen S. Yong, Paul A. Beavis, Nicole M. Haynes, Melvyn T. Chow, Mark J. Smyth, Michael H. Kershaw, Phillip K. Darcy - Clinical Cancer Research 2013 被引用: 700
- RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
著者: Sherene Loi, Sathana Dushyanthen, Paul A. Beavis, Roberto Salgado, Carsten Denkert, Peter Savas, S.E. Combs, David L. Rimm, Jennifer M. Giltnane, Mónica V. Estrada, Violeta Sánchez, Melinda E. Sanders, Rebecca S. Cook, Mark A. Pilkinton, S. Mallal, Kai Wang, Vincent A. Miller, Phil Stephens, Roman Yelensky, Franco D. Doimi, Henry Gómez, Sergey Ryzhov, Phillip K. Darcy, Carlos L. Arteaga, Justin M. Balko - Clinical Cancer Research 2015 被引用: 552
- BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1
著者: Simon J. Hogg, Stephin J. Vervoort, Sumit Deswal, Christopher J. Ott, Jason Li, Leonie A. Cluse, Paul A. Beavis, Phillip K. Darcy, Benjamin Martin, Andrew Spencer, Anna K. Traunbauer, Irina Sadovnik, Karin Bauer, Peter Valent, James E. Bradner, Johannes Zuber, Jake Shortt, Ricky W. Johnstone - Cell Reports 2017 被引用: 300
- T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models
著者: Déborah Meyran, Joe Jiang Zhu, Jeanne Butler, Daniela Tantalo, Sean Macdonald, Thu Ngoc Nguyen, Minyu Wang, Niko Thio, Criselle D’Souza, Vicky Mengfei Qin, Clare Y. Slaney, Aaron J Harrison, Kevin Sek, Pasquale Petrone, Kevin Thia, Lauren Giuffrida, Andrew M. Scott, Rachael Terry, Ben Tran, Jayesh Desai, H. Miles Prince, Simon J. Harrison, Paul A. Beavis, Michael H. Kershaw, Benjamin Solomon, Paul G. Ekert, Joseph A. Trapani, Phillip K. Darcy, Paul J. Neeson - Science Translational Medicine 2023 被引用: 97
- Trafficking of T Cells into Tumors
著者: Clare Y. Slaney, Michael H. Kershaw, Phillip K. Darcy - Cancer Research 2014 被引用: 406
- IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors
著者: Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Imran G. House, Junyun Lai, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Izabela Todorovski, Emily Gruber, Madison J. Kelly, Benjamin Solomon, Stephin J. Vervoort, Ricky W. Johnstone, Ian A. Parish, Paul J. Neeson, Lev M. Kats, Phillip K. Darcy, Paul A. Beavis - Molecular Therapy 2020 被引用: 107
- Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia
著者: David S. Ritchie, Paul J. Neeson, Amit Khot, Stefan Peinert, Tsin Yee Tai, Kellie M. Tainton, Karen Chen, Mandy Shin, Dominic Wall, Dirk Hönemann, Peter Gambell, David Westerman, Javier Haurat, Jennifer A. Westwood, Andrew M. Scott, L. Ya. Kravets, Michael Dickinson, Joseph A. Trapani, Mark J. Smyth, Phillip K. Darcy, Michael H. Kershaw, H. Miles Prince - Molecular Therapy 2013 被引用: 433
- Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy
著者: Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida, Jane K. Mills, Kevin Sek, Ryan Cross, Alexander J. Davenport, Liza B. John, Sherly Mardiana, Clare Y. Slaney, Ricky W. Johnstone, Joseph A. Trapani, John Stagg, Sherene Loi, Lev M. Kats, David Gyorki, Michael H. Kershaw, Phillip K. Darcy - Journal of Clinical Investigation 2017 被引用: 321
- Adenosine Receptor 2A Blockade Increases the Efficacy of Anti–PD-1 through Enhanced Antitumor T-cell Responses
著者: Paul A. Beavis, Nicole Milenkovski, Melissa A. Henderson, Liza B. John, Bertrand Allard, Sherene Loi, Michael H. Kershaw, John Stagg, Phillip K. Darcy - Cancer Immunology Research 2015 被引用: 329
- Activating and inhibitory receptors of natural killer cells
著者: Hollie J. Pegram, Daniel M. Andrews, Mark J. Smyth, Phillip K. Darcy, Michael H. Kershaw - Immunology and Cell Biology 2010 被引用: 544
