Kenneth E. Thummel
1990–2024 年に発表
- 121
- 論文数
- 22,364
- 被引用数
- 85
- h 指数
- 121
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine43.9%
- Pharmacology, Toxicology and Pharmaceutics39.4%
- Biochemistry, Genetics and Molecular Biology8.5%
- Engineering2.1%
- Computer Science2%
- Environmental Science0.8%
- その他3.3%
トピック
- Pharmacogenetics and Drug Metabolism16.5%
- Drug Transport and Resistance Mechanisms9.5%
- Pharmacological Effects and Toxicity Studies4.4%
- Drug-Induced Hepatotoxicity and Protection3%
- Computational Drug Discovery Methods2.9%
- Renal Transplantation Outcomes and Treatments1.8%
- その他61.9%
共著者
- Danny D. Shen21
- Kent L. Kunze19
- Mary F. Paine18
- Evan D. Kharasch17
- Erin G. Schuetz16
- Paul B. Watkins15
- Yvonne S. Lin15
- Allan E. Rettie11
- Mary F. Hébert11
- Connie L. Davis9
- Jashvant D. Unadkat8
- Christopher L. Marsh7
- Jatinder K. Lamba7
- Nina Isoherranen7
- Sidney D. Nelson7
- Steven Wrighton7
- Catherine K. Yeung6
- Deborah A. Nickerson6
- Edward J. Kelly6
- Jeannine M. Fisher6
- Kenneth S. Lown6
- Zhican Wang6
- James D. Perkins5
- John T. Slattery5
全論文
- Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
著者: Peter Kuehl, Jiong Zhang, Yvonne Lin, Jatinder K. Lamba, Mahfoud Assem, John D. Schuetz, Paul B. Watkins, Ann K. Daly, Steven Wrighton, Stephen D. Hall, P Maurel, Mary V. Relling, Cynthia Brimer, Kazuto Yasuda, Raman Venkataramanan, Stephen C. Strom, Kenneth E. Thummel, Mark S. Boguski, Erin G. Schuetz - Nature Genetics 2001 被引用: 2,161
- Development of a microphysiological model of human kidney proximal tubule function
著者: Elijah J. Weber, Alenka Chapron, Brian D. Chapron, Jenna L. Voellinger, Kevin A. Lidberg, Catherine K. Yeung, Zhican Wang, Yoshiyuki Yamaura, Dale W. Hailey, Thomas Neumann, Danny D. Shen, Kenneth E. Thummel, Kimberly A. Muczynski, Jonathan Himmelfarb, Edward J. Kelly - Kidney International 2016 被引用: 267
- Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants
著者: Sumit Bansal, C. Austin Zamarripa, Tory R. Spindle, Elise M. Weerts, Kenneth E. Thummel, Ryan G. Vandrey, Mary F. Paine, Jashvant D. Unadkat - Clinical Pharmacology & Therapeutics 2023 被引用: 62
- Genetic contribution to variable human CYP3A-mediated metabolism
著者: Jatinder K. Lamba, Yvonne S. Lin, Erin G. Schuetz, Kenneth E. Thummel - Advanced Drug Delivery Reviews 2002 被引用: 992
- Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
著者: Rakshit S. Tanna, James Nguyen, Deena L. Hadi, Preston K. Manwill, Laura Flores‐Bocanegra, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine - Pharmaceutics 2022 被引用: 64
- Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model
著者: Seung‐been Lee, Marsha M. Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L. Woodahl, Andrea Gaedigk, Kenneth E. Thummel, Deborah A. Nickerson - Genetics in Medicine 2018 被引用: 151
- CYP3A4 mutation causes vitamin D–dependent rickets type 3
著者: Jeffrey D. Roizen, Dong Li, Lauren O’Lear, M K Javaid, Nicholas J Shaw, Peter R. Ebeling, Hanh H. Nguyen, Christine Rodda, Kenneth E. Thummel, Tom D. Thacher, Håkon Håkonarson, Michael A. Levine - Journal of Clinical Investigation 2018 被引用: 118
- Cyp2e1 Activity Before and After Weight Loss in Morbidly Obese Subjects With Nonalcoholic Fatty Liver Disease
著者: Maurice G. Emery, Jeannine M. Fisher, Jenny Chien, Evan D. Kharasch, Patchen Dellinger, Kris V. Kowdley, Kenneth E. Thummel - Hepatology 2003 被引用: 176
- Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
著者: T. S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao‐bo Zhong, Yin-Chun Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer, Yvonne S Lin - Drug Metabolism and Disposition 2015 被引用: 175
- Drug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?
著者: Nina Isoherranen, Kenneth E. Thummel - Drug Metabolism and Disposition 2013 被引用: 208
- Interplay between vitamin D and the drug metabolizing enzyme CYP3A4
著者: Zhican Wang, Erin G. Schuetz, Yang Xu, Kenneth E. Thummel - The Journal of Steroid Biochemistry and Molecular Biology 2012 被引用: 123
- Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences
著者: Seung‐been Lee, Marsha M. Wheeler, Kenneth E. Thummel, Deborah A. Nickerson - Clinical Pharmacology & Therapeutics 2019 被引用: 92
- Assessing Transporter‐Mediated Natural Product‐Drug Interactions Via In vitro‐In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail
著者: James Nguyen, Dandan Tian, Rakshit S. Tanna, Deena L. Hadi, Sumit Bansal, Justina C. Calamia, Christopher M. Arian, Laura M. Shireman, Bálint Molnár, Miklós Horváth, Joshua J. Kellogg, Matthew E. Layton, John R. White, Nadja B. Cech, Richard D. Boyce, Jashvant D. Unadkat, Kenneth E. Thummel, Mary F. Paine - Clinical Pharmacology & Therapeutics 2020 被引用: 39
- Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom
著者: Rakshit S. Tanna, James Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine - Clinical Pharmacology & Therapeutics 2023 被引用: 27
- Interpreting Tacrolimus Concentrations During Pregnancy and Postpartum
著者: Mary F. Hébert, Songmao Zheng, Karen Hays, Danny D. Shen, Connie L. Davis, Jason G. Umans, Menachem Miodovnik, Kenneth E. Thummel, Thomas R. Easterling - Transplantation 2012 被引用: 144
- CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations
著者: Colin P. Hawkes, Dong Li, Håkon Håkonarson, Kevin Meyers, Kenneth E. Thummel, Michael A. Levine - The Journal of Clinical Endocrinology & Metabolism 2017 被引用: 100
- Translating Kratom-Drug Interactions: From Bedside to Bench and Back
著者: Rakshit S. Tanna, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine - Drug Metabolism and Disposition 2023 被引用: 24
- New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process
著者: Shiew‐Mei Huang, John M. Strong, Lei Zhang, Kellie S. Reynolds, Srikanth C. Nallani, Robert Temple, Sophia Abraham, Sayed Al Habet, Raman Baweja, Gilbert J. Burckart, Sang M. Chung, Philip M. Colangelo, David M. Frucht, Martin D. Green, Paul Hepp, Elena Karnaukhova, Hee Gyeong Ko, Jang-ik Lee, Patrick Marroum, Janet M. Norden, Wei Qiu, Atiqur Rahman, Solomon Sobel, Toni Stifano, Kenneth E. Thummel, Xiaoxiong Wei, Sally Usdin Yasuda, Jenny Zheng, Hong Zhao, Lawrence J. Lesko - The Journal of Clinical Pharmacology 2008 被引用: 400
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing
著者: Kelly A. Birdwell, Brian S. Decker, Julia M. Barbarino, Josh F. Peterson, C. Michael Stein, Wolfgang Sadée, Daqing Wang, Alexander A. Vinks, Yijing He, Jesse J. Swen, J. Steven Leeder, RHN van Schaik, Kenneth E. Thummel, Teri E. Klein, Kelly E. Caudle, Iain MacPhee - 2015 被引用: 88
- Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*
著者: Kenneth E. Thummel, Diarmuid O’Shea, Mary F. Paine, Danny D. Shen, Kent L. Kunze, James D. Perkins, G. Wilkinson - Clinical Pharmacology & Therapeutics 1996 被引用: 619
- Transcriptional Control of Intestinal Cytochrome P-4503A by 1α,25-Dihydroxy Vitamin D3
著者: Kenneth E. Thummel, Cynthia Brimer, Kazuto Yasuda, Jaideep V. Thottassery, Tauri Senn, Yvonne Lin, Hitoshi Ishizuka, Evan D. Kharasch, John D. Schuetz, Erin G. Schuetz - Molecular Pharmacology 2001 被引用: 324
- ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
著者: Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson, Kenneth E. Thummel - Drug Metabolism and Disposition 2004 被引用: 275
- Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport
著者: Catherine K. Yeung, Danny D. Shen, Kenneth E. Thummel, Jonathan Himmelfarb - Kidney International 2013 被引用: 213
- An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway
著者: Zhican Wang, Yvonne S. Lin, Xi Zheng, Tauri Senn, Takanori Hashizume, Michele Scian, Leslie J. Dickmann, Sidney D. Nelson, Thomas A. Baillie, Mary F. Hébert, David K. Blough, Connie L. Davis, Kenneth E. Thummel - Molecular Pharmacology 2011 被引用: 114
