Steven Wrighton
1984–2011 年に発表
- 86
- 論文数
- 18,813
- 被引用数
- 77
- h 指数
- 86
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Pharmacology, Toxicology and Pharmaceutics44.1%
- Medicine34.7%
- Biochemistry, Genetics and Molecular Biology8.9%
- Computer Science7.1%
- Chemistry1.3%
- Environmental Science1.2%
- その他2.7%
トピック
- Pharmacogenetics and Drug Metabolism19.8%
- Drug Transport and Resistance Mechanisms10.5%
- Computational Drug Discovery Methods6.1%
- Pharmacological Effects and Toxicity Studies3.4%
- Drug-Induced Hepatotoxicity and Protection2.9%
- Analytical Chemistry and Chromatography2.2%
- その他55.1%
共著者
- Barbara J. Ring22
- Paul B. Watkins20
- Mark VandenBranden17
- Erin G. Schuetz15
- Sean Ekins13
- Stephen D. Hall13
- Philip S. Guzelian11
- James H. Wikel9
- Kenneth E. Thummel7
- Stephen C. Strom7
- Jennifer S. Gillespie6
- S N Binkley6
- David T. Molowa5
- James A. Eckstein5
- Jeffrey Stevens5
- John D. Schuetz5
- Kazuto Yasuda5
- Kenneth S. Lown5
- Patrick Maurel5
- Gianpaolo Bravi4
- Joseph C. Kolars4
- Mitchell A. Hamman4
- Anne H. Dantzig3
- D. Kim Turgeon3
全論文
- Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
著者: Peter Kuehl, Jiong Zhang, Yvonne Lin, Jatinder K. Lamba, Mahfoud Assem, John D. Schuetz, Paul B. Watkins, Ann K. Daly, Steven Wrighton, Stephen D. Hall, P Maurel, Mary V. Relling, Cynthia Brimer, Kazuto Yasuda, Raman Venkataramanan, Stephen C. Strom, Kenneth E. Thummel, Mark S. Boguski, Erin G. Schuetz - Nature Genetics 2001 被引用: 2,161
- Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
著者: Daqing Wang, Yingying Guo, Steven Wrighton, George Cooke, Wolfgang Sadée - The Pharmacogenomics Journal 2010 被引用: 507
- THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE
著者: Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence L. Gan, Scott Grimm, John Y. Kao, Shang‐Ying P. King, Gerald T. Miwa, Lan Ni, Gondi Kumar, James F. McLeod, R. Scott Obach, Stanley Roberts, Amy L. Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, José M. Vega, John Walsh, Steven Wrighton - Drug Metabolism and Disposition 2003 被引用: 784
- Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7
著者: J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James A. Eckstein, Kenneth J. Ruterbories, Mitchell A. Hamman, Stephen D. Hall, Steven Wrighton - Drug Metabolism and Disposition 2002 被引用: 468
- Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression
著者: Vishal Lamba, Jatinder K. Lamba, Kazuto Yasuda, Stephen C. Strom, Julio Dávila, Michael L. Hancock, James D. Fackenthal, Peter K. Rogan, Barbara J. Ring, Steven Wrighton, Erin G. Schuetz - Journal of Pharmacology and Experimental Therapeutics 2003 被引用: 400
- Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans
著者: Nagy A. Farid, Atsushi Kurihara, Steven Wrighton - The Journal of Clinical Pharmacology 2009 被引用: 391
- Present and future in vitro approaches for drug metabolism
著者: Sean Ekins, Barbara J. Ring, James E. Grace, Donna J. McRobie-Belle, Steven Wrighton - Journal of Pharmacological and Toxicological Methods 2000 被引用: 227
- The Human Hepatic Cytochromes P450 Involved in Drug Metabolism
著者: Steven Wrighton, Jeffrey Stevens - Critical Reviews in Toxicology 1992 被引用: 947
- Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.
著者: Paul B. Watkins, Steven Wrighton, Erin G. Schuetz, David T. Molowa, Philip S. Guzelian - Journal of Clinical Investigation 1987 被引用: 483
- Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.
著者: Paul B. Watkins, Scott A Murray, L G Winkelman, Douglas M. Heuman, Steven Wrighton, Philip S. Guzelian - Journal of Clinical Investigation 1989 被引用: 351
- In Vitro Glucuronidation Using Human Liver Microsomes and The Pore-Forming Peptide Alamethicin
著者: Michael B. Fisher, Kristina Campanale, Bradley L. Ackermann, Mark VandenBranden, Steven Wrighton - Drug Metabolism and Disposition 2000 被引用: 342
- The Conduct of In Vitro and In Vivo Drug‐Drug Interaction Studies: A PhRMA Perspective
著者: Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence L. Gan, Scott Grimm, John Y. Kao, Shang‐Ying P. King, Gerald T. Miwa, Lan Ni, Gondi Kumar, James F. McLeod, Scott R. Obach, Stanley Roberts, Amy L. Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, José M. Vega, John Walsh, Steven Wrighton - The Journal of Clinical Pharmacology 2003 被引用: 309
- Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.
著者: Paul B. Watkins, Steven Wrighton, Jeffrey L. Barnett, Kenneth S. Lown, Kent L. Kunze, Kenneth E. Thummel, Joseph C. Kolars - Drug Metabolism and Disposition 1994 被引用: 305
- Progress in predicting human ADME parameters in silico
著者: Sean Ekins, Chris L. Waller, Peter W. Swaan, Gabriele Cruciani, Steven Wrighton, James H. Wikel - Journal of Pharmacological and Toxicological Methods 2000 被引用: 277
- Molecular and physical mechanisms of first-pass extraction.
著者: Stephen D. Hall, Kenneth E. Thummel, Paul B. Watkins, Kenneth S. Lown, Leslie Z. Benet, Mary F. Paine, Robert R. Mayo, D. Kim Turgeon, David G. Bailey, Robert J. Fontana, Steven Wrighton - 1999 被引用: 239
- Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide
著者: John R. Cashman, Sang B. Park, Ziping Yang, Steven Wrighton, Peyton Jacob, Neal L. Benowitz - Chemical Research in Toxicology 1992 被引用: 213
- THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS*
著者: Steven Wrighton, Erin G. Schuetz, Kenneth E. Thummel, Danny D. Shen, Kenneth R. Korzekwa, Paul B. Watkins - Drug Metabolism Reviews 2000 被引用: 211
- The human drug metabolizing cytochromes P450
著者: Steven Wrighton, Mark VandenBranden, Barbara J. Ring - Journal of Pharmacokinetics and Biopharmaceutics 1996 被引用: 166
- The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
著者: Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, E.J. Perkins, Steven Wrighton, Kenneth J. Ruterbories, Miho Kazui, Nagy A. Farid - Drug Metabolism and Disposition 2008 被引用: 127
- The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism*†
著者: Michael B. Fisher, Mary F. Paine, Timothy J. Strelevitz, Steven Wrighton - Drug Metabolism Reviews 2001 被引用: 371
- Selectivity of the Multidrug Resistance Modulator, LY335979, for P-Glycoprotein and Effect on Cytochrome P-450 Activities
著者: Anne H. Dantzig, Robert L. Shepard, K L Law, Linda B. Tabas, Susan E. Pratt, Jennifer S. Gillespie, S N Binkley, Michael T. Kuhfeld, James J. Starling, Steven Wrighton - Journal of Pharmacology and Experimental Therapeutics 1999 被引用: 179
- Differential Modulation of UDP-Glucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3-glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes
著者: J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, Kristina Campanale, David Jones, Stephen D. Hall, Steven Wrighton - Drug Metabolism and Disposition 2002 被引用: 152
- Effects of Antipsychotic Drugs on Ito, INa, Isus, IK1, and hERG: QT Prolongation, Structure Activity Relationship, and Network Analysis
著者: William Crumb, Sean Ekins, R. Dustan Sarazan, James H. Wikel, Steven Wrighton, Christopher Carlson, Charles M. Beasley - Pharmaceutical Research 2006 被引用: 89
- Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
著者: Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wenkai Guo, Mariam Ehsani, Xiliang Wang, He Wang, Yuewei Qian, Kenneth J. Ruterbories, Steven Wrighton, E.J. Perkins - Drug Metabolism and Disposition 2011 被引用: 72
