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Mark X. Sliwkowski

1992–2024 年に発表

59
論文数
30,512
被引用数
57
h 指数
59
i10 指数

被引用数

Mark X. Sliwkowski の年別被引用数1984 年: 被引用 1 件1992 年: 被引用 6 件1993 年: 被引用 26 件1994 年: 被引用 46 件1995 年: 被引用 94 件1996 年: 被引用 78 件1997 年: 被引用 125 件1998 年: 被引用 83 件1999 年: 被引用 97 件2000 年: 被引用 130 件2001 年: 被引用 136 件2002 年: 被引用 155 件2003 年: 被引用 240 件2004 年: 被引用 261 件2005 年: 被引用 297 件2006 年: 被引用 275 件2007 年: 被引用 301 件2008 年: 被引用 295 件2009 年: 被引用 273 件2010 年: 被引用 300 件2011 年: 被引用 350 件2012 年: 被引用 352 件2013 年: 被引用 420 件2014 年: 被引用 480 件2015 年: 被引用 358 件2016 年: 被引用 305 件2017 年: 被引用 267 件2018 年: 被引用 260 件2019 年: 被引用 831 件2020 年: 被引用 721 件2021 年: 被引用 680 件2022 年: 被引用 573 件2023 年: 被引用 419 件2024 年: 被引用 663 件2025 年: 被引用 345 件2026 年: 被引用 16 件1985〜1991 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 3,417 件、この内訳の 33.4%中国: 引用元論文 909 件、この内訳の 8.9%イギリス: 引用元論文 596 件、この内訳の 5.8%ドイツ: 引用元論文 509 件、この内訳の 5%イタリア: 引用元論文 430 件、この内訳の 4.2%日本: 引用元論文 364 件、この内訳の 3.6%フランス: 引用元論文 323 件、この内訳の 3.1%スイス: 引用元論文 289 件、この内訳の 2.8%カナダ: 引用元論文 278 件、この内訳の 2.7%スペイン: 引用元論文 271 件、この内訳の 2.6%インド: 引用元論文 232 件、この内訳の 2.3%韓国: 引用元論文 211 件、この内訳の 2.1%
0%33.4%その他 23.5%

機関

分野

  • Medicine64%
  • Biochemistry, Genetics and Molecular Biology22.4%
  • Chemistry3.2%
  • Neuroscience2.8%
  • Immunology and Microbiology2.5%
  • Computer Science1.9%
  • その他3.2%

トピック

  • HER2/EGFR in Cancer Research15.3%
  • Monoclonal and Polyclonal Antibodies Research12.1%
  • Lung Cancer Treatments and Mutations3.2%
  • Glycosylation and Glycoproteins Research2.9%
  • Peptidase Inhibition and Analysis2.1%
  • CAR-T cell therapy research1.9%
  • その他62.5%

共著者

全論文

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  1. Untangling the ErbB signalling network

    著者: Yosef Yarden, Mark X. Sliwkowski - Nature Reviews Molecular Cell Biology 2001 被引用: 6,942

  2. Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

    著者: Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger, Lisa Crocker, Kathryn L. Parsons, Elaine Mai, Walter A. Blättler, John M. Lambert, Ravi Chari, Robert J. Lutz, Wai Lee Wong, Frederic S. Jacobson, Hartmut Koeppen, Ralph Schwall, Sara Kenkare-Mitra, Susan D. Spencer, Mark X. Sliwkowski - Cancer Research 2008 被引用: 1,678

  3. Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor

    著者: Jennifer L. Stamos, Mark X. Sliwkowski, Charles Eigenbrot - Journal of Biological Chemistry 2002 被引用: 1,526

  4. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

    著者: Jagath R. Junutula, Helga Raab, Suzanna Clark, Sunil Bhakta, Douglas D. Leipold, Sylvia Weir, Yvonne Chen, Michelle Simpson, Siao Ping Tsai, Mark S. Dennis, Yanmei Lu, Y. Gloria Meng, Carl Ng, Jihong Yang, Chien C Lee, Eileen Duenas, Jeffrey Gorrell, Viswanatham Katta, Amy Kim, Kevin S. McDorman, Kelly M. Flagella, Rayna Venook, Sarajane Ross, Susan D. Spencer, Wai Lee Wong, Henry B. Lowman, Richard Vandlen, Mark X. Sliwkowski, Richard H. Scheller, Paul Polakis, William Mallet - Nature Biotechnology 2008 被引用: 1,354

  5. Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

    著者: Ben‐Quan Shen, Keyang Xu, Luna Liu, Helga Raab, Sunil Bhakta, Margaret Kenrick, Kathryn Parsons-Reponte, Janet Tien, Shang‐Fan Yu, Elaine Mai, Dongwei Li, Jay Tibbitts, Jakub Baudys, Ola M. Saad, Suzie J. Scales, Paul J McDonald, Philip E. Hass, Charles Eigenbrot, Trung Van Nguyen, Willy A. Solis, Reina N. Fuji, Kelly M. Flagella, Darshana Patel, Susan D. Spencer, Leslie A. Khawli, Allen Ebens, Wai Lee Wong, Richard Vandlen, Surinder Kaur, Mark X. Sliwkowski, Richard H. Scheller, Paul Polakis, Jagath R. Junutula - Nature Biotechnology 2012 被引用: 999

  6. Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer

    著者: Teemu T. Junttila, Guangmin Li, Kathryn L. Parsons, Gail D. Lewis Phillips, Mark X. Sliwkowski - Breast Cancer Research and Treatment 2010 被引用: 533

  7. Treatment of HER2-positive breast cancer: current status and future perspectives

    著者: Carlos L. Arteaga, Mark X. Sliwkowski, C. Kent Osborne, Edith A. Perez, Fabio Puglisi, Luca Gianni - Nature Reviews Clinical Oncology 2011 被引用: 871

  8. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

    著者: Matthew C. Franklin, Kendall D. Carey, F.F. Vajdos, Daniel J. Leahy, Abraham M. de Vos, Mark X. Sliwkowski - Cancer Cell 2004 被引用: 1,115

  9. Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941

    著者: Teemu T. Junttila, Robert W. Akita, Kathryn L. Parsons, Carter T. Fields, Gail D. Lewis Phillips, Lori S. Friedman, Deepak Sampath, Mark X. Sliwkowski - Cancer Cell 2009 被引用: 831

  10. Potential Mechanisms for Thrombocytopenia Development with Trastuzumab Emtansine (T-DM1)

    著者: Hirdesh Uppal, Estelle Doudement, Kaushiki Mahapatra, Walter C. Darbonne, Daniela Bumbaca, Ben‐Quan Shen, Xiaoyan Du, Ola M. Saad, Kristin Harden Bowles, Steve Olsen, Gail D. Lewis Phillips, Dylan P. Hartley, Mark X. Sliwkowski, Sandhya Girish, Donna M. Dambach, Vanitha Ramakrishnan - Clinical Cancer Research 2014 被引用: 211

  11. Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells

    著者: Guangmin Li, Jun Guo, Ben‐Quan Shen, Daniela Bumbaca Yadav, Mark X. Sliwkowski, Lisa Crocker, Jennifer A. Lacap, Gail D. Lewis Phillips - Molecular Cancer Therapeutics 2018 被引用: 184

  12. Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates

    著者: Niña G. Caculitan, Josefa Chuh, Yong Ma, Donglu Zhang, Katherine R. Kozak, Yichin Liu, Thomas H. Pillow, Jack Sadowsky, Tommy K. Cheung, Qui Phung, Benjamin Haley, Byoung-Chul Lee, Robert W. Akita, Mark X. Sliwkowski, Andrew G. Polson - Cancer Research 2017 被引用: 154

  13. A Central Role for HER3 in HER2 -Amplified Breast Cancer: Implications for Targeted Therapy

    著者: Si Tuen Lee-Hoeflich, Lisa Crocker, Evelyn Yao, Thinh Q. Pham, Xander Munroe, Klaus P. Hoeflich, Mark X. Sliwkowski, Howard M. Stern - Cancer Research 2008 被引用: 646

  14. Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination Therapy

    著者: Gail D. Lewis Phillips, Carter T. Fields, Guangmin Li, Donald Dowbenko, Gabriele Schaefer, Kathy D. Miller, Fabrice André, Howard A. Burris, Kathy S. Albain, Nadia Harbeck, Véronique Dièras, Diana Crivellari, Fang Ting Liang, Ellie Guardino, Steven R. Olsen, Lisa Crocker, Mark X. Sliwkowski - Clinical Cancer Research 2013 被引用: 199

  15. The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results

    著者: Gail D. Lewis Phillips, Guangmin Li, Jun Guo, Shang‐Fan Yu, Carter T. Fields, Genee Lee, Donglu Zhang, Peter S. Dragovich, Thomas H. Pillow, BinQing Wei, Jack Sadowsky, Douglas D. Leipold, Tim Wilson, Amrita V. Kamath, Michael Mamounas, M. Violet Lee, Ola M. Saad, Voleak Choeurng, Alexander Ungewickell, Sharareh Monemi, Lisa Crocker, Kevin Kalinsky, Shanu Modi, Kyung Hae Jung, Erika Hamilton, Patricia LoRusso, Ian E. Krop, Melissa M. Schutten, Renee Commerford, Mark X. Sliwkowski, Eunpi Cho - Nature Communications 2024 被引用: 46

  16. Phase I Study of Trastuzumab-DM1, an HER2 Antibody-Drug Conjugate, Given Every 3 Weeks to Patients With HER2-Positive Metastatic Breast Cancer

    著者: Ian E. Krop, Muralidhar Beeram, Shanu Modi, Suzanne F. Jones, Scott N. Holden, Wei Yu, Sandhya Girish, Jay Tibbitts, Joo‐Hee Yi, Mark X. Sliwkowski, Fred Jacobson, Stuart Lutzker, Howard A. Burris - Journal of Clinical Oncology 2010 被引用: 596

  17. Endocytosis and Sorting of ErbB2 and the Site of Action of Cancer Therapeutics Trastuzumab and Geldanamycin

    著者: Cary D. Austin, Ann M. De Mazière, Paul I. Pisacane, Suzanne M. van Dijk, Charles Eigenbrot, Mark X. Sliwkowski, Judith Klumperman, Richard H. Scheller - Molecular Biology of the Cell 2004 被引用: 489

  18. An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

    著者: Antony W. Burgess, Hyun‐Soo Cho, Charles Eigenbrot, Kathryn M. Ferguson, Thomas Garrett, Daniel J. Leahy, Mark A. Lemmon, Mark X. Sliwkowski, Colin W. Ward, Shigeyuki Yokoyama - Molecular Cell 2003 被引用: 900

  19. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

    著者: David B. Agus, Robert W. Akita, William D. Fox, Gail D. Lewis Phillips, Brian Higgins, Paul I. Pisacane, Julie A. Lofgren, Charles Tindell, Douglas P. Evans, Krista Maiese, Howard I. Scher, Mark X. Sliwkowski - Cancer Cell 2002 被引用: 888

  20. Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

    著者: Jagath R. Junutula, Kelly M. Flagella, Richard Graham, Kathryn L. Parsons, Edward Ha, Helga Raab, Sunil Bhakta, Trung Van Nguyen, Debra L. Dugger, Guangmin Li, Elaine Mai, Gail D. Lewis Phillips, Hajime Hiraragi, Reina N. Fuji, Jay Tibbitts, Richard Vandlen, Susan D. Spencer, Richard H. Scheller, Paul Polakis, Mark X. Sliwkowski - Clinical Cancer Research 2010 被引用: 292

  21. Antibody Therapeutics in Cancer

    著者: Mark X. Sliwkowski, Ira Mellman - Science 2013 被引用: 541

  22. A Two-in-One Antibody against HER3 and EGFR Has Superior Inhibitory Activity Compared with Monospecific Antibodies

    著者: Gabriele Schaefer, Lauric Haber, Lisa Crocker, Steven Shia, Lily Shao, Donald Dowbenko, Klára Tótpál, Anne Wong, Chingwei V. Lee, Scott Stawicki, Robyn Clark, Carter T. Fields, Gail D. Lewis Phillips, Rodney A. Prell, Dimitry M. Danilenko, Yvonne Franke, Jean-Philippe Stéphan, Ji‐Young Hwang, Yan Wu, Jenny Boström, Mark X. Sliwkowski, Germaine Fuh, Charles Eigenbrot - Cancer Cell 2011 被引用: 335

  23. Kinetic Analysis of Epidermal Growth Factor Receptor Somatic Mutant Proteins Shows Increased Sensitivity to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Erlotinib

    著者: Kendall D. Carey, Andrew J. Garton, Maria S. Romero, Jennifer Kahler, Stuart Thomson, Sarajane Ross, Frances Park, John D. Haley, Neil W. Gibson, Mark X. Sliwkowski - Cancer Research 2006 被引用: 443

  24. Oncogenic ERBB3 Mutations in Human Cancers

    著者: Bijay S. Jaiswal, Noelyn M. Kljavin, Eric Stawiski, Emily Chan, Chaitali Parikh, Steffen Durinck, Subhra Chaudhuri, Kanan Pujara, Joseph Guillory, Kyle A. Edgar, Vasantharajan Janakiraman, Rolf‐Peter Scholz, Krista K. Bowman, Maria Lorenzo, Hong Li, Jiansheng Wu, Wenlin Yuan, Brock A. Peters, Zhengyan Kan, Jeremy Stinson, Michelle Mak, Zora Modrušan, Charles Eigenbrot, Ron Firestein, Howard M. Stern, Krishnaraj Rajalingam, Gabriele Schaefer, Mark Merchant, Mark X. Sliwkowski, Frédéric J. de Sauvage, Somasekar Seshagiri - Cancer Cell 2013 被引用: 347