Michael K. Lee
1988–2025 年に発表
- 82
- 論文数
- 24,063
- 被引用数
- 66
- h 指数
- 78
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine62.1%
- Biochemistry, Genetics and Molecular Biology22.2%
- Neuroscience11.7%
- Immunology and Microbiology1.3%
- Nursing0.8%
- Chemistry0.4%
- その他1.5%
トピック
- Alzheimer's disease research and treatments12.4%
- Parkinson's Disease Mechanisms and Treatments9%
- Amyotrophic Lateral Sclerosis Research4.7%
- Neuroinflammation and Neurodegeneration Mechanisms3.1%
- Nuclear Receptors and Signaling2.7%
- Neuroscience and Neuropharmacology Research2.6%
- その他65.5%
共著者
- Donald L. Price16
- David Borchelt14
- Neal G. Copeland13
- Don W. Cleveland12
- Juan C. Troncoso12
- Sangram S. Sisodia12
- Nancy A. Jenkins11
- Ted M. Dawson10
- Olga Pletniková8
- Gopal Thinakaran6
- Hilda H. Slunt6
- Donald H. Dean5
- Lee J. Martin5
- Philip C. Wong5
- Valina L. Dawson5
- Wanda L.H. Stirling5
- Alfonso Araque4
- Andrew J. Saykin4
- Connie Nakano4
- Emanuela Colla4
- Emily H. Trittschuh4
- Grace Kim4
- Héctor Martell-Martínez4
- Jesse Mez4
全論文
- Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase
著者: Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson, Guilian Xu, Victoria Gonzales, Nancy A. Jenkins, Neal G. Copeland, Michael K. Lee, Linda H. Younkin, Steven L. Wagner, Steven G. Younkin, David Borchelt - Human Molecular Genetics 2003 被引用: 1,599
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
著者: Venu M. Nemani, Wei Lü, Victoria Berge, Ken Nakamura, Bibiana Onoa, Michael K. Lee, Farrukh A. Chaudhry, Roger A. Nicoll, Robert H. Edwards - Neuron 2010 被引用: 1,067
- Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
著者: Michael K. Lee, Wanda L.H. Stirling, Yanqun Xu, Xueying Xu, Dike Qui, Allen S. Mandir, Ted M. Dawson, Neal G. Copeland, Nancy A. Jenkins, Don L. Price - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 被引用: 840
- α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton
著者: Dalila G. Ordonez, Michael K. Lee, Mel Β. Feany - Neuron 2017 被引用: 235
- Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future
著者: Yonas E. Geda, Lon S. Schneider, Laura N. Gitlin, David S. Miller, Gwenn S. Smith, J. Simon Bell, Jovier D. Evans, Michael K. Lee, Anton P. Porsteinsson, Krista L. Lanctôt, Paul B. Rosenberg, David L. Sultzer, Paul T. Francis, Henry Brodaty, Prasad P. Padala, Chiadikaobi Onyike, Luis Agüera Ortiz, Sonia Ancoli‐Israel, Donald L. Bliwise, Jennifer L. Martin, Michael V. Vitiello, Kristine Yaffe, Phyllis C. Zee, Nathan Herrmann, Robert A. Sweet, Clive Ballard, Ni A. Khin, Cara L. Alfaro, Patrick S. Murray, Susan K. Schultz, Constantine G. Lyketsos, Neuropsychiatric Syndromes Professional Interest Area of ISTAART - Alzheimer s & Dementia 2013 被引用: 381
- Endoplasmic Reticulum Stress Is Important for the Manifestations of α-SynucleinopathyIn Vivo
著者: Emanuela Colla, Philippe Coune, Ying Liu, Olga Pletniková, Juan C. Troncoso, Takeshi Iwatsubo, Bernard L. Schneider, Michael K. Lee - Journal of Neuroscience 2012 被引用: 380
- Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo
著者: David Borchelt, Gopal Thinakaran, Christopher B. Eckman, Michael K. Lee, Frances Davenport, Tamara Ratovitsky, Cristian-Mihail Prada, Grace Kim, Sophia Seekins, Debra Yager, Hilda H. Slunt, Rong Wang, Mary Seeger, Allan I. Levey, Sam Gandy, Neal G. Copeland, Nancy A. Jenkins, Donald L. Price, Steven G. Younkin, Sangram S. Sisodia - Neuron 1996 被引用: 1,485
- Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-SynucleinopathyIn Vivo
著者: Emanuela Colla, Poul Henning Jensen, Olga Pletniková, Juan C. Troncoso, Charles Glabe, Michael K. Lee - Journal of Neuroscience 2012 被引用: 328
- Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases
著者: Jeanne M.M. Tan, Esther Wong, Donald S. Kirkpatrick, Olga Pletniková, Han Seok Ko, Shiam-Peng Tay, Michelle W. L. Ho, Juan C. Troncoso, Steven P. Gygi, Michael K. Lee, Valina L. Dawson, Ted M. Dawson, Kah‐Leong Lim - Human Molecular Genetics 2007 被引用: 445
- ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
著者: Lucie Bruijn, Mark W. Bêcher, Michael K. Lee, Kenton L. Anderson, N.A. Jenkins, Neal G. Copeland, Sangram S. Sisodia, Jeffrey D. Rothstein, David Borchelt, Donald L. Price, Don W. Cleveland - Neuron 1997 被引用: 1,330
- Aggregation promoting C-terminal truncation of α-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations
著者: Wenxue Li, Neva West, Emanuela Colla, Olga Pletniková, Juan C. Troncoso, Laura Marsh, Ted M. Dawson, Pekka Jäkälä, Tobias Hartmann, Donald L. Price, Michael K. Lee - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 被引用: 467
- Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer
著者: Jenna H. Newman, Charles B. Chesson, Nora L. Herzog, Praveen K. Bommareddy, Salvatore Aspromonte, Russell Pepe, Ricardo Estupinian, Mones Aboelatta, Stuti Buddhadev, Saeed Tarabichi, Michael K. Lee, Shengguo Li, Daniel Medina, Eileena F. Giurini, Kajal Gupta, Gabriel Guevara-Aleman, Marco Rossi, Christina Nowicki, Abdulkareem Abed, Josef W. Goldufsky, Joseph R. Broucek, Raquel Redondo, David Rotter, Sachin R. Jhawar, Shang-Jui Wang, Frederick J. Kohlhapp, Howard L. Kaufman, Paul G. Thomas, Vineet Gupta, Timothy M. Kuzel, Jochen Reiser, Joyce Paras, Michael P. Kane, Eric A. Singer, Jyoti Malhotra, Lisa Denzin, Derek B. Sant’Angelo, Arnold B. Rabson, Leonard Y. Lee, Ahmed Lasfar, John Langenfeld, Jason M. Schenkel, Mary J. Fidler, Emily S. Ruiz, Amanda L. Marzo, Jai S. Rudra, Ann W. Silk, Andrew Zloza - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 被引用: 191
- Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death
著者: Lee J. Martin, Yan Pan, Ann C. Price, Wanda Sterling, Neal G. Copeland, Nancy A. Jenkins, Donald L. Price, Michael K. Lee - Journal of Neuroscience 2006 被引用: 679
- Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson’s Disease
著者: Philipp Portz, Michael K. Lee - Cells 2021 被引用: 56
- The Microtubule-associated Protein Tau Is Extensively Modified with O-linked N-acetylglucosamine
著者: C. Shane Arnold, GailV.W. Johnson, Robert N. Cole, Dennis L.-Y. Dong, Michael K. Lee, Gerald W. Hart - Journal of Biological Chemistry 1996 被引用: 342
- Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
著者: Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal Dehankar, Cory C. Funk, Jordan Wilkins, Анна Степанова, Tara O’Hagan, Alexander Galkin, Jarred J. Nesbitt, Xiujuan Zhu, Utkarsh Tripathi, Slobodan Macura, Tamar Tchkonia, Tamar Pirtskhalava, James L. Kirkland, Rachel A. Kudgus, Renee A. Schoon, Joel M. Reid, Yu Yamazaki, Takahisa Kanekiyo, Song Zhang, Emirhan Nemutlu, Petras P. Dzeja, Adam Jaspersen, Ye In Christopher Kwon, Michael K. Lee, Eugenia Trushina - Communications Biology 2021 被引用: 69
- An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
著者: Philip C. Wong, Carlos A. Pardo, David Borchelt, Michael K. Lee, Neal G. Copeland, Nancy A. Jenkins, Sangram S. Sisodia, Don W. Cleveland, Donald L. Price - Neuron 1995 被引用: 1,437
- Amyloid Pathology Is Associated with Progressive Monoaminergic Neurodegeneration in a Transgenic Mouse Model of Alzheimer's Disease
著者: Ying Liu, Mi‐Jeong Yoo, Alena Savonenko, Wanda L.H. Stirling, Donald L. Price, David Borchelt, Laura A. Mamounas, W. Ernest Lyons, Mary E. Blue, Michael K. Lee - Journal of Neuroscience 2008 被引用: 209
- Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.
著者: David Borchelt, Michael K. Lee, Hilda S. Slunt, Michael Guarnieri, Zhenshu Xu, Philip C. Wong, R. H. Brown, Donald L. Price, Sangram S. Sisodia, Don W. Cleveland - National Academy of Sciences, Proceedings of the National Academy of Sciences 1994 被引用: 628
- Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
著者: Balvindar Singh, Ana Covelo, Héctor Martell-Martínez, Carmen Nanclares, Mathew A. Sherman, Emmanuel Okematti, Joyce Meints, Peter J. Teravskis, Christopher Gallardo, Alena Savonenko, Michael A. Benneyworth, Sylvain Lesné, Dezhi Liao, Alfonso Araque, Michael K. Lee - Acta Neuropathologica 2019 被引用: 88
- α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment
著者: Md. Razaul Karim, Elly E. Liao, Jaekwang Kim, Joyce Meints, Héctor Martínez, Olga Pletniková, Juan C. Troncoso, Michael K. Lee - Molecular Neurodegeneration 2020 被引用: 66
- Lessons from inducible pluripotent stem cell models on neuronal senescence in aging and neurodegeneration
著者: Isabelle R. de Luzy, Michael K. Lee, William C. Mobley, Lorenz Studer - Nature Aging 2024 被引用: 28
- Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins
著者: David Borchelt, Tamara Ratovitski, Judy van Lare, Michael K. Lee, Vicki Gonzales, Nancy A. Jenkins, Neal G. Copeland, Donald L. Price, Sangram S. Sisodia - Neuron 1997 被引用: 1,030
- Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform
著者: Takeshi Ishihara, Ming Hong, Bin Zhang, Yasushi Nakagawa, Michael K. Lee, John Q. Trojanowski, Virginia M.‐Y. Lee - Neuron 1999 被引用: 560
