William C. Mobley
1974–2025 年に発表
- 122
- 論文数
- 21,045
- 被引用数
- 83
- h 指数
- 119
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine37.1%
- Neuroscience28.8%
- Biochemistry, Genetics and Molecular Biology26.3%
- Agricultural and Biological Sciences1.6%
- Engineering1.2%
- Materials Science1%
- その他4%
トピック
- Nerve injury and regeneration6.9%
- Alzheimer's disease research and treatments6.3%
- Neurogenesis and neuroplasticity mechanisms4.1%
- Down syndrome and intellectual disability research3.3%
- Neuroscience and Neuropharmacology Research2.9%
- Cellular transport and secretion2.7%
- その他73.8%
共著者
- Pavel V. Belichenko20
- Chengbiao Wu17
- Alexander M. Kleschevnikov14
- Ahmad Salehi12
- Xu‐Qiao Chen11
- J Valletta10
- Charles J. Epstein8
- Ann Becker7
- Charles L. Howe7
- Elizabeth Head6
- Jonathan D. Cooper6
- Michael S. Rafii6
- Robert A. Rissman6
- David M. Holtzman5
- Donald L. Price5
- Jean‐Dominique Delcroix5
- Michael V. Johnston5
- Rudolph E. Tanzi5
- Steven L. Wagner5
- André Strydom4
- Angela J. Villar4
- Bianxiao Cui4
- Eliezer Masliah4
- Eric C. Beattie4
全論文
- Enabling Technologies for Personalized and Precision Medicine
著者: Dean Ho, Stephen R. Quake, Edward R.B. McCabe, Wee Joo Chng, Edward Kai‐Hua Chow, Xianting Ding, Bruce D. Gelb, Geoffrey S. Ginsburg, Jason Hassenstab, Chih‐Ming Ho, William C. Mobley, Garry P. Nolan, Steven T. Rosen, Patrick Tan, Yun Yen, Ali Zarrinpar - Trends in biotechnology 2020 被引用: 484
- Reversing a model of Parkinson’s disease with in situ converted nigral neurons
著者: Hao Qian, Xinjiang Kang, Jing Hu, Dongyang Zhang, Zhengyu Liang, Fan Meng, Xuan Zhang, Yuanchao Xue, Roy Maimon, Steven F. Dowdy, Neal K. Devaraj, Zhuan Zhou, William C. Mobley, Don W. Cleveland, Xiang‐Dong Fu - Nature 2020 被引用: 488
- Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species
著者: Xu‐Qiao Chen, William C. Mobley - Frontiers in Neuroscience 2019 被引用: 290
- Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair
著者: Michael V. Sofroniew, Charles L. Howe, William C. Mobley - Annual Review of Neuroscience 2001 被引用: 1,277
- Dementia in Down's syndrome
著者: Clive Ballard, William C. Mobley, John Hardy, Gareth Williams, Anne Corbett - The Lancet Neurology 2016 被引用: 263
- BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons
著者: Guillermo Moya‐Alvarado, Reynaldo Tiburcio‐Félix, María Raquel Ibáñez, Alejandro A Aguirre-Soto, Miguel V. Guerra, Chengbiao Wu, William C. Mobley, Eran Perlson, Francisca C. Bronfman - eLife 2023 被引用: 98
- Down syndrome and Alzheimer's disease: Common pathways, common goals
著者: Dean M. Hartley, Thomas Blumenthal, María C. Carrillo, Gilbert DiPaolo, Lucille Esralew, Katheleen Gardiner, Ann-Charlotte Granholm, Khalid Iqbal, Michael Krams, Cynthia A. Lemere, Ira T. Lott, William C. Mobley, Seth Ness, Ralph A. Nixon, Huntington Potter, Roger H. Reeves, Marwan N. Sabbagh, Wayne Silverman, Benjamin Tycko, Michelle Sie Whitten, Thomas Wısnıewskı - Alzheimer s & Dementia 2014 被引用: 302
- Further understanding the connection between Alzheimer's disease and Down syndrome
著者: Heather M. Snyder, Lisa J. Bain, Adam M. Brickman, María C. Carrillo, Anna J. Esbensen, Joaquı́n M. Espinosa, Fabian‐Xosé Fernandez, Juan Fortea, Sigan L. Hartley, Elizabeth Head, James A. Hendrix, Priya S. Kishnani, Florence Lai, Patrick J. Lao, Cynthia A. Lemere, William C. Mobley, Elliott J. Mufson, Huntington Potter, Shahid Zaman, Ann‐Charlotte Granholm, H. Diana Rosas, André Strydom, Michelle Sie Whitten, Michael S. Rafii - Alzheimer s & Dementia 2020 被引用: 103
- Opportunities, barriers, and recommendations in Down syndrome research
著者: James A. Hendrix, Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson, Lisa J. Bain, Nicole Baumer, Anita Bhattacharyya, Dusan Bogunovic, Kelly N. Botteron, George T. Capone, Priya Chandan, Isabelle Chase, Brian Chicoine, Cécile Cieuta‐Walti, Lara R. DeRuisseau, Sophie Durand, Anna J. Esbensen, Juan Fortea, Sandra Giménez, Ann‐Charlotte Granholm, Laura J. Mattie, Elizabeth Head, Hampus Hillerstrom, Lisa M. Jacola, Matthew P. Janicki, Joan Jasien, Angela R. Kamer, Raymond D. Kent, Bernard Khor, Jeanne B. Lawrence, Catherine Lemonnier, Amy Feldman Lewanda, William C. Mobley, Paul E. Moore, Linda Nelson, Nicolas M. Oreskovic, Ricardo S. Osorio, David Patterson, Sonja A. Rasmussen, Roger H. Reeves, Nancy Roizen, Stephanie L. Santoro, Stephanie L. Sherman, Nasreen Talib, Ignacio E. Tapia, Kyle M. Walsh, Steven F. Warren, A. Nicole White, G. William Wong, John S. Yi - Translational Science of Rare Diseases 2021 被引用: 99
- Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses
著者: Xu‐Qiao Chen, William C. Mobley - Frontiers in Neuroscience 2019 被引用: 178
- CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons
著者: Gong‐Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket Rajan Gupte, Ranen Aviner, Patrick Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette R. Geller, Cathy Hou, Cristina Danita, Lydia‐Marie Joubert, Michael F. Schmid, Serena Yeung, Judith Frydman, William C. Mobley, Chengbiao Wu, Leslie M. Thompson, Wah Chiu - Nature Communications 2023 被引用: 64
- Widespread changes in dendritic and axonal morphology in Mecp2‐mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks
著者: Pavel V. Belichenko, Elena E. Wright, Nadia P. Belichenko, Eliezer Masliah, Hong Hua Li, William C. Mobley, Uta Francke - The Journal of Comparative Neurology 2009 被引用: 277
- Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome
著者: Michael S. Rafii, Olivier Sol, William C. Mobley, Saskia Delpretti, Brian G. Skotko, Anna Burke, Marwan N. Sabbagh, Shauna H. Yuan, Robert A. Rissman, Margaret B. Pulsifer, Casey L. Evans, A. Carol Evans, Gregory Beth, Nicolas Fournier, Julian Gray, Antonio Melo dos Santos, Valerie Hliva, Marija Vukicevic, Marie Kosco‐Vilbois, Johannes Streffer, Andrea Pfeifer, Howard Feldman - JAMA Neurology 2022 被引用: 54
- Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration
著者: Wei Xu, April M. Weissmiller, Joseph White, Fang Fang, Xinyi Wang, Yiwen Wu, Matthew L. Pearn, Xiaobei Zhao, Mariko Sawa, Shengdi Chen, Shermali Gunawardena, Jianqing Ding, William C. Mobley, Chengbiao Wu - Journal of Clinical Investigation 2016 被引用: 184
- Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention
著者: Kevin D. Rynearson, Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Phuong Nguyen, Brenda Hug, Mariko Sawa, Ann Becker, Brian Spencer, Jazmin Florio, Michael Mante, Bahar Salehi, Carlos Arias, Douglas Galasko, Brian P. Head, Graham Johnson, Jiunn H. Lin, Steven K. Duddy, Robert A. Rissman, William C. Mobley, Gopal Thinakaran, Rudolph E. Tanzi, Steven L. Wagner - The Journal of Experimental Medicine 2021 被引用: 72
- Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model
著者: Mariko Sawa, Cassia Overk, Ann Becker, Dominique Derse, Ricardo Albay, Kim Weldy, Ahmad Salehi, Thomas G. Beach, Eric Doran, Elizabeth Head, Yang Yu, William C. Mobley - Alzheimer s & Dementia 2021 被引用: 60
- Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
著者: Maria Z. Kounnas, Anne M. Danks, Soan Cheng, Curtis M. Tyree, Elizabeth Ackerman, Xulun Zhang, Kwangwook Ahn, Phuong Nguyen, Dan Comer, Long Mao, Chengzhi Yu, David Pleynet, Paul J. DiGregorio, Gönül Veliçelebi, Kenneth A. Stauderman, William T. Comer, William C. Mobley, Yue‐Ming Li, Sangram S. Sisodia, Rudolph E. Tanzi, Steven L. Wagner - Neuron 2010 被引用: 254
- Targeting increased levels of APP in Down syndrome: Posiphen‐mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model
著者: Xu‐Qiao Chen, Ahmad Salehi, Matthew L. Pearn, Cassia Overk, Phuong D. Nguyen, Alexander M. Kleschevnikov, Maria L. Maccecchini, William C. Mobley - Alzheimer s & Dementia 2020 被引用: 54
- Disentangling self from pain: mindfulness meditation–induced pain relief is driven by thalamic–default mode network decoupling
著者: Gabriel Riegner, Grace Posey, Valeria Oliva, Youngkyoo Jung, William C. Mobley, Fadel Zeidan - Pain 2022 被引用: 41
- Lessons from inducible pluripotent stem cell models on neuronal senescence in aging and neurodegeneration
著者: Isabelle R. de Luzy, Michael K. Lee, William C. Mobley, Lorenz Studer - Nature Aging 2024 被引用: 28
- Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome
著者: Xin Wang, Yingjun Zhao, Xiaofei Zhang, Hedieh Badie, Ying Zhou, Yangling Mu, Li Shen Loo, Lei Cai, Robert C. Thompson, Bo Yang, Yaomin Chen, Peter F. Johnson, Chengbiao Wu, Guojun Bu, William C. Mobley, Dongxian Zhang, Fred H. Gage, Barbara Ranscht, Yun‐wu Zhang, Stuart A. Lipton, Wanjin Hong, Huaxi Xu - Nature Medicine 2013 被引用: 263
- The 50th anniversary of the discovery of trisomy 21: The past, present, and future of research and treatment of Down syndrome
著者: André Mégarbané, Aimé Ravel, Clotilde Mircher, Franck Sturtz, Yann Grattau, M O Rethoré, Jean‐Maurice Delabar, William C. Mobley - Genetics in Medicine 2009 被引用: 261
- Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis
著者: Yingjun Zhao, I‐Chu Tseng, Charles J. Heyser, Edward Rockenstein, Michael Mante, Anthony Adame, Qiuyang Zheng, Timothy Y. Huang, Xin Wang, Pharhad Eli Arslan, Paramita Chakrabarty, Chengbiao Wu, Guojun Bu, William C. Mobley, Yun‐wu Zhang, Peter St George‐Hyslop, Eliezer Masliah, Paul Fraser, Huaxi Xu - Neuron 2015 被引用: 101
- TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease
著者: Xiaobei Zhao, Xu‐Qiao Chen, Eugene Kiwo Han, Yue Hu, Paul K. Paik, Zhiyong Ding, Julia Overman, Alice Lau, Sarah H. Shahmoradian, Wah Chiu, Leslie M. Thompson, Chengbiao Wu, William C. Mobley - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 99
