Ralph A. Nixon
1978–2024 年に発表
- 171
- 論文数
- 43,392
- 被引用数
- 113
- h 指数
- 171
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine59.9%
- Biochemistry, Genetics and Molecular Biology23.3%
- Neuroscience11.3%
- Nursing1%
- Immunology and Microbiology0.9%
- Materials Science0.7%
- その他2.9%
トピック
- Alzheimer's disease research and treatments13.3%
- Autophagy in Disease and Therapy6.9%
- Neuroinflammation and Neurodegeneration Mechanisms3.4%
- Cholinesterase and Neurodegenerative Diseases2.7%
- Parkinson's Disease Mechanisms and Treatments2.6%
- Cellular transport and secretion2.5%
- その他68.6%
共著者
- Anne M. Cataldo33
- Paul M. Mathews24
- Asok Kumar23
- Panaiyur S. Mohan23
- Ying Jiang21
- Corrinne M. Peterhoff20
- Philip Stavrides17
- Stephen D. Schmidt17
- Dun‐Sheng Yang15
- Mala V. Rao15
- Ju‐Hyun Lee13
- Aidong Yuan12
- Efrat Levy12
- Monika Pawlik11
- Ana María Cuervo10
- Karen Duff9
- Martin J. Berg9
- Wai Haung Yu9
- Yutaka Satō9
- Veeranna8
- Marc Mercken7
- Sandipkumar Darji7
- Stephen D. Ginsberg7
- Anna Pensalfini6
全論文
- Alzheimer disease
著者: David S. Knopman, Hélène Amieva, Ronald C. Petersen, Gaël Chételat, David M. Holtzman, Bradley T. Hyman, Ralph A. Nixon, David T. Jones - Nature Reviews Disease Primers 2021 被引用: 2,395
- Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
著者: Ju‐Hyun Lee, Dun‐Sheng Yang, Chris N. Goulbourne, Eunju Im, Philip Stavrides, Anna Pensalfini, Han Chan, Cédric Bouchet‐Marquis, Cynthia Bleiwas, Martin J. Berg, Chunfeng Huo, James Peddy, Monika Pawlik, Efrat Levy, Mala Rao, M. Staufenbiel, Ralph A. Nixon - Nature Neuroscience 2022 被引用: 614
- The role of autophagy in neurodegenerative disease
著者: Ralph A. Nixon - Nature Medicine 2013 被引用: 2,041
- Neurofilaments and Neurofilament Proteins in Health and Disease
著者: Aidong Yuan, Mala V. Rao, Veeranna, Ralph A. Nixon - Cold Spring Harbor Perspectives in Biology 2017 被引用: 728
- Neurofilament Proteins as Biomarkers to Monitor Neurological Diseases and the Efficacy of Therapies
著者: Aidong Yuan, Ralph A. Nixon - Frontiers in Neuroscience 2021 被引用: 285
- Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study
著者: Ralph A. Nixon, Jerzy Węgiel, Asok Kumar, Wai Haung Yu, Corrinne M. Peterhoff, Anne M. Cataldo, Ana María Cuervo - Journal of Neuropathology & Experimental Neurology 2005 被引用: 1,580
- Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases
著者: Ralph A. Nixon, David C. Rubinsztein - Nature Reviews Molecular Cell Biology 2024 被引用: 300
- Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
著者: Barry Boland, Wai Haung Yu, Olga Corti, Bertrand Mollereau, Alexandre Henriques, Erwan Bézard, Greg Pastores, David C. Rubinsztein, Ralph A. Nixon, Michael R. Duchen, Giovanna R. Mallucci, Guido Kroemer, Beth Levine, Eeva‐Liisa Eskelinen, Fanny Mochel, Michael Spedding, Caroline Louis, Olivier R. Martin, Mark J. Millan - Nature Reviews Drug Discovery 2018 被引用: 549
- Disorders of lysosomal acidification—The emerging role of v-ATPase in aging and neurodegenerative disease
著者: Daniel J. Colacurcio, Ralph A. Nixon - Ageing Research Reviews 2016 被引用: 540
- Neurofilaments: neurobiological foundations for biomarker applications
著者: Arie Gafson, Nicolas R. Barthélemy, Pascale Bomont, Roxana O. Carare, Heather D. Durham, Jean-Pierre Julien, Jens Kühle, David Leppert, Ralph A. Nixon, Roy O. Weller, Henrik Zetterberg, Paul M. Matthews - Brain 2020 被引用: 317
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
著者: Ju‐Hyun Lee, Wai Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S. Mohan, Corrinne M. Peterhoff, Devin M. Wolfe, Marta Martínez‐Vicente, Ashish C. Massey, Guy Sovak, Yasuo Uchiyama, David Westaway, Ana María Cuervo, Ralph A. Nixon - Cell 2010 被引用: 1,216
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
著者: Barry Boland, Ashok Kumar, Sarah Lee, Frances M. Platt, Jerzy Węgiel, Wai Haung Yu, Ralph A. Nixon - Journal of Neuroscience 2008 被引用: 1,114
- Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome
著者: Anne M. Cataldo, Corrinne M. Peterhoff, Juan C. Troncoso, Teresa Gómez‐Isla, Bradley T. Hyman, Ralph A. Nixon - American Journal Of Pathology 2000 被引用: 850
- Amyloid precursor protein and endosomal‐lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease
著者: Ralph A. Nixon - The FASEB Journal 2017 被引用: 397
- Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
著者: Matteo Bordi, Martin J. Berg, Panaiyur S. Mohan, Corrinne M. Peterhoff, Melissa J. Alldred, Shaoli Che, Stephen D. Ginsberg, Ralph A. Nixon - Autophagy 2016 被引用: 350
- Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification
著者: Ju‐Hyun Lee, Mary Kate McBrayer, Devin M. Wolfe, Luke J. Haslett, Asok Kumar, Yutaka Sato, Pearl P.Y. Lie, Panaiyur S. Mohan, Erin E. Coffey, Uday B. Kompella, Claire H. Mitchell, Emyr Lloyd‐Evans, Ralph A. Nixon - Cell Reports 2015 被引用: 360
- Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
著者: Wai Haung Yu, Ana María Cuervo, Asok Kumar, Corrinne M. Peterhoff, Stephen D. Schmidt, Ju‐Hyun Lee, Panaiyur S. Mohan, Marc Mercken, Mark R. Farmery, Lars O. Tjernberg, Ying Jiang, Karen Duff, Yasuo Uchiyama, Jan Näslund, Paul M. Mathews, Anne M. Cataldo, Ralph A. Nixon - The Journal of Cell Biology 2005 被引用: 970
- Autophagy, amyloidogenesis and Alzheimer disease
著者: Ralph A. Nixon - Journal of Cell Science 2007 被引用: 750
- A gene toolbox for monitoring autophagy transcription
著者: Matteo Bordi, Rossella De Cegli, Beatrice Testa, Ralph A. Nixon, Andrea Ballabio, Francesco Cecconi - Cell Death and Disease 2021 被引用: 145
- Autophagy failure in Alzheimer's disease—locating the primary defect
著者: Ralph A. Nixon, Dun‐Sheng Yang - Neurobiology of Disease 2011 被引用: 638
- The aging lysosome: An essential catalyst for late-onset neurodegenerative diseases
著者: Ralph A. Nixon - Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2020 被引用: 152
- Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
著者: Sooyeon Lee, Yutaka Satō, Ralph A. Nixon - Journal of Neuroscience 2011 被引用: 470
- Lysosome trafficking and signaling in health and neurodegenerative diseases
著者: Pearl P.Y. Lie, Ralph A. Nixon - Neurobiology of Disease 2018 被引用: 264
- Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr 682 -phosphorylated APP βCTF
著者: Eunju Im, Ying Jiang, Philip Stavrides, Sandipkumar Darji, Hediye Erdjument‐Bromage, Thomas A. Neubert, Jun Yong Choi, Jerzy Węgiel, Ju‐Hyun Lee, Ralph A. Nixon - Science Advances 2023 被引用: 73
