Karen Duff
1992–2025 年に発表
- 125
- 論文数
- 34,281
- 被引用数
- 94
- h 指数
- 122
- i10 指数
被引用数
引用元
国・地域
機関
- Harvard University1.5%
- Massachusetts General Hospital0.9%
- University College London0.9%
- Inserm0.7%
- Mayo Clinic in Florida0.7%
- Columbia University0.7%
- その他94.6%
分野
- Medicine62.7%
- Biochemistry, Genetics and Molecular Biology18%
- Neuroscience14.9%
- Engineering1%
- Nursing0.6%
- Computer Science0.5%
- その他2.3%
トピック
- Alzheimer's disease research and treatments20.3%
- Neuroinflammation and Neurodegeneration Mechanisms4.5%
- Cholinesterase and Neurodegenerative Diseases4.2%
- Neuroscience and Neuropharmacology Research4.1%
- Computational Drug Discovery Methods3%
- Dementia and Cognitive Impairment Research2.8%
- その他61.1%
共著者
- John Hardy16
- Lili Wang14
- Wai Haung Yu14
- Helen Y. Figueroa13
- Li Liu12
- Mathieu Herman12
- John J. LaFrancois11
- Emmanuel Planel10
- Ralph A. Nixon9
- Scott A. Small9
- Yasuji Matsuoka9
- Dennis W. Dickson7
- Henry Houlden7
- Hongjun Fu7
- Mark P. Burns7
- Peter Davies7
- Xin Yu7
- Cindy Zehr6
- Jordi Pérez‐Tur6
- Lorenzo M. Refolo6
- Mike Hutton6
- Richard Crook6
- Stephanie L. Fowler6
- Vicki Olm6
全論文
- Neuronal activity enhances tau propagation and tau pathology in vivo
著者: Jessica Wu, S. Abid Hussaini, Isle Bastille, G Rodriguez, Ana Mrejeru, Kelly C. Rilett, David W. Sanders, Casey Cook, Hongjun Fu, Rick A.C.M. Boonen, Mathieu Herman, Eden Nahmani, Sheina Emrani, Yvette H. Figueroa, Marc I. Diamond, Catherine L. Clelland, Selina Wray, Karen Duff - Nature Neuroscience 2016 被引用: 848
- Selective vulnerability in neurodegenerative diseases
著者: Hongjun Fu, John Hardy, Karen Duff - Nature Neuroscience 2018 被引用: 601
- Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease
著者: Robin Chan, Tiago Gil Oliveira, Etty Cortés, Lawrence S. Honig, Karen Duff, Scott A. Small, Markus R. Wenk, Guanghou Shui, Gilbert Di Paolo - Journal of Biological Chemistry 2011 被引用: 658
- Trans-Synaptic Spread of Tau Pathology In Vivo
著者: Li Liu, Valérie Drouet, Jessica Wu, Menno P. Witter, Scott A. Small, Catherine L. Clelland, Karen Duff - PLoS ONE 2012 被引用: 1,008
- Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling
著者: Natura Myeku, Catherine L. Clelland, Sheina Emrani, Nikolay V. Kukushkin, Wai Haung Yu, Alfred L. Goldberg, Karen Duff - Nature Medicine 2015 被引用: 446
- Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease
著者: Shuo Chen, Yuzhou Chang, Liangping Li, Diana Acosta, Yang Li, Qi Guo, Cankun Wang, Emir Turkes, Cody Morrison, Dominic Julian, Mark E. Hester, Douglas W. Scharre, Chintda Santiskulvong, Sarah XueYing Song, Jasmine Plummer, Geidy E. Serrano, Thomas G. Beach, Karen Duff, Qin Ma, Hongjun Fu - Acta Neuropathologica Communications 2022 被引用: 130
- Tau Oligomer–Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease
著者: Raquel N. Taddei, Romain Perbet, Anastasie Maté de Gérando, Anne Wiedmer, María V. Sánchez-Mico, Theresa Connors Stewart, Angelica Gaona, Alexandra Melloni, Ana C. Amaral, Karen Duff, Matthew P. Frosch, Teresa Gómez‐Isla - JAMA Neurology 2023 被引用: 105
- A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
著者: Hongjun Fu, Andrea Possenti, Rosie Freer, Yoshikazu Nakano, Nancy C. Hernandez Villegas, Maoping Tang, Paula Victoria Maglio Cauhy, Benjamin Lassus, Shuo Chen, Stephanie L. Fowler, Helen Y. Figueroa, Edward D. Huey, Gail V.W. Johnson, Michele Vendruscolo, Karen Duff - Nature Neuroscience 2018 被引用: 275
- Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
著者: Wai Haung Yu, Ana María Cuervo, Asok Kumar, Corrinne M. Peterhoff, Stephen D. Schmidt, Ju‐Hyun Lee, Panaiyur S. Mohan, Marc Mercken, Mark R. Farmery, Lars O. Tjernberg, Ying Jiang, Karen Duff, Yasuo Uchiyama, Jan Näslund, Paul M. Mathews, Anne M. Cataldo, Ralph A. Nixon - The Journal of Cell Biology 2005 被引用: 970
- Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
著者: Jessica Wu, Mathieu Herman, Li Liu, Sabrina Simoes, Christopher M. Acker, Helen Y. Figueroa, Joshua Steinberg, Martin Margittai, Rakez Kayed, Chiara Zurzolo, Gilbert Di Paolo, Karen Duff - Journal of Biological Chemistry 2012 被引用: 547
- Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
著者: Mauro Fà, Daniela Puzzo, Roberto Piacentini, Anna Staniszewski, H. Zhang, Marı́a Antonia Baltrons, Domenica Donatella Li Puma, Ishita Chatterjee, Jinlin Li, Faisal Saeed, Hanna L. Berman, Cristian Ripoli, Walter Gulisano, Jose Gonzalez, Huilai Tian, Joseph Costa, Patrícia Luciana da Costa Lopez, Eliot J. Davidowitz, Wai Haung Yu, Vahram Haroutunian, Lewis M. Brown, Agostino Palmeri, Einar M. Sigurdsson, Karen Duff, Andrew F. Teich, Lawrence S. Honig, Michael R. Sierks, James G. Moe, Luciano D'adamio, Claudio Grassi, Nicholas M. Kanaan, Paul E. Fraser, Ottavio Arancio - Scientific Reports 2016 被引用: 271
- Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology
著者: Tal Nuriel, Sergio Angulo, Usman Khan, Archana Ashok, Qiuying Chen, Helen Y. Figueroa, Sheina Emrani, Li Liu, Mathieu Herman, Geoffrey Barrett, Valerie Savage, Luna Buitrago, Efraín Cepeda-Prado, Christine Fung, Eliana Goldberg, Steven S. Gross, S. Abid Hussaini, Herman Moreno, Scott A. Small, Karen Duff - Nature Communications 2017 被引用: 196
- Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
著者: Jada Lewis, Eileen McGowan, Julia M. Rockwood, Heather L. Melrose, Parimala Nacharaju, Marjon van Slegtenhorst, Katrina Gwinn, Michael P. Murphy, Matt Baker, Xin Yu, Karen Duff, John Hardy, Anthony Corral, Wen-Lang Lin, Shu-Hui Yen, Dennis W. Dickson, Peter Davies, Mike Hutton - Nature Genetics 2000 被引用: 1,369
- Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria
著者: Estela Área-Gómez, Ad J.C. de Groof, István Boldogh, Thomas D. Bird, Gary E. Gibson, Carla M. Koehler, Wai Haung Yu, Karen Duff, Michael P. Yaffe, Liza A. Pon, Eric A. Schon - American Journal Of Pathology 2009 被引用: 402
- Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
著者: Cathy Andorfer, Yvonne Kress, Marisol Espinoza, Rohan de Silva, Kerry L. Tucker, Yves‐Alain Barde, Karen Duff, Peter Davies - Journal of Neurochemistry 2003 被引用: 723
- Chronic effects of inflammation on tauopathies
著者: Connor Langworth-Green, Saisha Patel, Zane Jaunmuktane, Edwin Jabbari, Huw R. Morris, Maria Thom, Andrew J. Lees, John Hardy, Michael S. Zandi, Karen Duff - The Lancet Neurology 2023 被引用: 79
- Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
著者: Leigh A. Holcomb, Marcia N. Gordon, Eileen McGowan, Xin Yu, Stan Benkovic, Paul Jantzen, Kristal Wright, Irene Saad, Ryan Mueller, Dave Morgan, Sunny Sanders, Cindy Zehr, Kassandra O'Campo, John Hardy, Cristian-Mihail Prada, Chris Eckman, Steve Younkin, Karen Hsiao, Karen Duff - Nature Medicine 1998 被引用: 1,403
- Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
著者: Wendy Noble, Emmanuel Planel, Cindy Zehr, Vicki Olm, Jordana L. Meyerson, Farhana E. Suleman, Kate Gaynor, Lili Wang, John J. LaFrancois, Boris Feinstein, Mark P. Burns, Pavan Krishnamurthy, Wen Yi, Ratan V. Bhat, Jada Lewis, Dennis W. Dickson, Karen Duff - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 被引用: 697
- In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
著者: Georg Meisl, Eric Hidari, Kieren Allinson, Timothy Rittman, Sarah L. DeVos, Justin S. Sanchez, Catherine K. Xu, Karen Duff, Keith A. Johnson, James B. Rowe, Bradley T. Hyman, Tuomas P. J. Knowles, David Klenerman - Science Advances 2021 被引用: 131
- Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease
著者: Hongjun Fu, G Rodriguez, Mathieu Herman, Sheina Emrani, Eden Nahmani, Geoffrey Barrett, Helen Y. Figueroa, Eliana Goldberg, S. Abid Hussaini, Karen Duff - Neuron 2017 被引用: 303
- Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases
著者: Saïda Abounit, Jessica Wu, Karen Duff, Guiliana Soraya Victoria, Chiara Zurzolo - Prion 2016 被引用: 205
- Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease
著者: Usman Khan, Li Liu, Frank A. Provenzano, Diego E. Berman, Caterina P. Profaci, Richard P. Sloan, Richard Mayeux, Karen Duff, Scott A. Small - Nature Neuroscience 2013 被引用: 586
- Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
著者: Julia Tsai, Jaime Grutzendler, Karen Duff, Wen‐Biao Gan - Nature Neuroscience 2004 被引用: 573
- Cdk5 Is a Key Factor in Tau Aggregation and Tangle Formation In Vivo
著者: Wendy Noble, Vicki Olm, Kazuyuki Takata, Evelyn Casey, O Mary, Jordana L. Meyerson, Kate Gaynor, John J. LaFrancois, Lili Wang, Takayuki Kondo, Peter Davies, Mark P. Burns, Veeranna, Ralph A. Nixon, Dennis W. Dickson, Yasuji Matsuoka, Michael K. Ahlijanian, Lit-Fui Lau, Karen Duff - Neuron 2003 被引用: 507
