Rakez Kayed
1999–2025 年に発表
- 126
- 論文数
- 34,544
- 被引用数
- 75
- h 指数
- 119
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine59.4%
- Biochemistry, Genetics and Molecular Biology21.9%
- Neuroscience12.8%
- Immunology and Microbiology1%
- Materials Science1%
- Computer Science0.7%
- その他3.2%
トピック
- Alzheimer's disease research and treatments20.4%
- Neuroinflammation and Neurodegeneration Mechanisms5.8%
- Cholinesterase and Neurodegenerative Diseases4.4%
- Computational Drug Discovery Methods3.6%
- Neuroscience and Neuropharmacology Research3.2%
- Prion Diseases and Protein Misfolding2.6%
- その他60%
共著者
- Urmi Sengupta37
- Charles Glabe26
- Nemil Bhatt23
- Diana L. Castillo‐Carranza20
- Mauro Montalbano17
- Nicha Puangmalai17
- Julia E. Gerson16
- Cristian A. Lasagna‐Reeves13
- Marcos J. Guerrero-Muñoz13
- George R. Jackson12
- Salomé McAllen11
- Giulio Taglialatela10
- Anna Ellsworth8
- Cynthia Jerez7
- Filippa Lo Cascio7
- Kelly T. Dineley7
- Saskia Milton7
- Stephanie García7
- Alice Bittar6
- Elizabeth Head5
- Leiana Fung5
- Michela Marcatti5
- Sagar Gaikwad5
- Yingxin Zhao5
全論文
- NLRP3 inflammasome activation drives tau pathology
著者: Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V. Schmidt, Ana Vieira‐Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M. McManus, Darío Tejera, Angelika Griep, Francesco Santarelli, Frederic Brosseron, Sabine Opitz, James Stunden, Maximilian Merten, Rakez Kayed, Douglas T. Golenbock, David Blum, Eicke Latz, Luc Buée, Michael T. Heneka - Nature 2019 被引用: 1,559
- Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
著者: Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd, M. Paul Murphy, Todd E. Golde, Rakez Kayed, Raju Metherate, Mark P. Mattson, Yama Akbari, Frank M. LaFerla - Neuron 2003 被引用: 4,130
- iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
著者: Edsel M. Abud, Ricardo N. Ramírez, Eric S. Martinez, Luke M. Healy, Cecilia Nguyen, Sean A. Newman, Andriy V. Yeromin, Vanessa M. Scarfone, Samuel E. Marsh, Cristhian Fimbres, Chad A. Caraway, Gianna Fote, Abdullah M. Madany, Anshu Agrawal, Rakez Kayed, Karen H. Gylys, Michael D. Cahalan, B. Cummings, Jack P. Antel, A Mortazavi, Monica J. Carson, Wayne W. Poon, Mathew Blurton‐Jones - Neuron 2017 被引用: 1,174
- Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis
著者: Phuong H. Nguyen, Ayyalusamy Ramamoorthy, Bikash R. Sahoo, Jie Zheng, Peter Faller, John E. Straub, Laura Domı́nguez, Joan–Emma Shea, Nikolay V. Dokholyan, Alfonso De Simone, Buyong Ma, Ruth Nussinov, Saeed Najafi, Sơn Tùng Ngô, Antoine Loquet, Mara Chiricotto, Pritam Ganguly, James McCarty, Mai Suan Li, Carol K. Hall, Yiming Wang, Yifat Miller, Simone Melchionna, Birgit Habenstein, Štěpán Timr, Jiaxing Chen, Brianna Hnath, Birgit Strodel, Rakez Kayed, Sylvain Lesné, Guanghong Wei, Fabio Sterpone, Andrew J. Doig, Philippe Derreumaux - Chemical Reviews 2021 被引用: 668
- Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases
著者: Urmi Sengupta, Rakez Kayed - Progress in Neurobiology 2022 被引用: 273
- Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo
著者: Fusheng Yang, Giselle P. Lim, Aynun N. Begum, Oliver J. Ubeda, Mychica Simmons, Surendra S. Ambegaokar, Pingping P. Chen, Rakez Kayed, Charles Glabe, Sally A. Frautschy, Gregory M. Cole - Journal of Biological Chemistry 2004 被引用: 2,306
- The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy
著者: Urmi Sengupta, Ashley N. Nilson, Rakez Kayed - EBioMedicine 2016 被引用: 744
- Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia
著者: Sagar Gaikwad, Nicha Puangmalai, Alice Bittar, Mauro Montalbano, Stephanie García, Salomé McAllen, Nemil Bhatt, Minal Sonawane, Urmi Sengupta, Rakez Kayed - Cell Reports 2021 被引用: 217
- Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
著者: Rakez Kayed, Elizabeth Head, Jennifer L. Thompson, Theresa M. McIntire, Saskia Milton, Carl W. Cotman, Charles Glabe - Science 2003 被引用: 4,088
- Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons
著者: Zhi Ruan, Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Nemil Bhatt, Kayo Takamatsu-Yukawa, Jianqiao Hu, Yuzhi Wang, Samuel Hersh, Maria Ericsson, Santhi Gorantla, Howard E. Gendelman, Rakez Kayed, Seiko Ikezu, Jennifer I. Luebke, Tsuneya Ikezu - Brain 2020 被引用: 276
- Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
著者: Cristian A. Lasagna‐Reeves, Diana L. Castillo‐Carranza, Urmi Sengupta, Audra L. Clos, George R. Jackson, Rakez Kayed - Molecular Neurodegeneration 2011 被引用: 618
- Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
著者: Cristian A. Lasagna‐Reeves, Diana L. Castillo‐Carranza, Urmi Sengupta, José Sarmiento, Juan C. Troncoso, George R. Jackson, Rakez Kayed - The FASEB Journal 2012 被引用: 525
- Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
著者: Cristian A. Lasagna‐Reeves, Diana L. Castillo‐Carranza, Urmi Sengupta, Marcos J. Guerrero-Muñoz, Takaki Kiritoshi, Volker Neugebauer, George R. Jackson, Rakez Kayed - Scientific Reports 2012 被引用: 507
- Senescence, brain inflammation, and oligomeric tau drive cognitive decline in Alzheimer's disease: Evidence from clinical and preclinical studies
著者: Sagar Gaikwad, Sudipta Senapati, Md. Anzarul Haque, Rakez Kayed - Alzheimer s & Dementia 2023 被引用: 101
- Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
著者: Jessica Wu, Mathieu Herman, Li Liu, Sabrina Simoes, Christopher M. Acker, Helen Y. Figueroa, Joshua Steinberg, Martin Margittai, Rakez Kayed, Chiara Zurzolo, Gilbert Di Paolo, Karen Duff - Journal of Biological Chemistry 2012 被引用: 547
- Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy
著者: Stacy A. Hussong, Andy Banh, Candice E. Van Skike, Angela O. Dorigatti, Stephen F. Hernandez, Matthew J. Hart, Beatriz Ferrán, Haneen Makhlouf, Maria Gaczyńska, Paweł A. Osmulski, Salomé McAllen, Kelly T. Dineley, Zoltán Ungvári, Viviana Pérez, Rakez Kayed, Verónica Galván - Nature Communications 2023 被引用: 71
- Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
著者: Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing, Carl W. Cotman, Mihaela Necula, Lawrence Margol, Jessica Wu, Leonid Breydo, Jennifer L. Thompson, Suhail Rasool, Tatyana Gurlo, Peter C. Butler, Charles Glabe - Molecular Neurodegeneration 2007 被引用: 782
- Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
著者: Laura J. Blair, Bryce A. Nordhues, Shannon E. Hill, K. Matthew Scaglione, John C. O’Leary, Sarah N. Fontaine, Leonid Breydo, Bo Zhang, Pengfei Li, Li Wang, Carl W. Cotman, Henry L. Paulson, Martin Muschol, Vladimir N. Uversky, Torsten Klengel, Elisabeth B. Binder, Rakez Kayed, Todd E. Golde, Nicole Berchtold, Chad A. Dickey - Journal of Clinical Investigation 2013 被引用: 321
- RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory
著者: Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, Rakez Kayed, Charles Glabe, Austin J. Yang, Michela Gallagher, Karen H. Ashe - Nature 2006 被引用: 2,758
- Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer’s Disease
著者: Luca Troncone, Marco Luciani, Matthew Coggins, Elissa H. Wilker, Cheng‐Ying Ho, Kari Elise Codispoti, Matthew P. Frosch, Rakez Kayed, Federica del Monte - Journal of the American College of Cardiology 2016 被引用: 201
- Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross‐seeding behavior
著者: Gaurav Ghag, Nemil Bhatt, Daniel V. Cantu, Marcos J. Guerrero-Muñoz, Anna Ellsworth, Urmi Sengupta, Rakez Kayed - Protein Science 2018 被引用: 157
- Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer’s disease
著者: Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Sagar Gaikwad, Mauro Montalbano, Arijit Bhuyan, Stephanie García, Salomé McAllen, Minal Sonawane, Cynthia Jerez, Yingxin Zhao, Rakez Kayed - Journal of Biological Chemistry 2022 被引用: 63
- Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer’s disease from a ferroptosis perspective
著者: Paul J. Derry, Muralidhar L. Hegde, George R. Jackson, Rakez Kayed, James M. Tour, Ah-Lim Tsai, Thomas A. Kent - Progress in Neurobiology 2019 被引用: 143
- Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies
著者: Diana L. Castillo‐Carranza, Ashley N. Nilson, Candice E. Van Skike, Jordan B. Jahrling, Kishan B. Patel, Prajesh Garach, Julia E. Gerson, Urmi Sengupta, Jose F. Abisambra, Peter T. Nelson, Juan C. Troncoso, Zoltán Ungvári, Verónica Galván, Rakez Kayed - Aging and Disease 2017 被引用: 122
