Philip D. Jeffrey
1966–2025 年に発表
- 76
- 論文数
- 25,122
- 被引用数
- 64
- h 指数
- 75
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology56.7%
- Medicine30.6%
- Neuroscience4.6%
- Immunology and Microbiology2.2%
- Agricultural and Biological Sciences1.7%
- Materials Science0.9%
- その他3.3%
トピック
- Ubiquitin and proteasome pathways7.4%
- Cancer-related Molecular Pathways6.6%
- Protein Degradation and Inhibitors4%
- Epigenetics and DNA Methylation2.5%
- Autophagy in Disease and Therapy2.2%
- Microtubule and mitosis dynamics2.2%
- その他75.1%
共著者
- Nikola P. Pavletich16
- Yigong Shi15
- Frederick M. Hughson12
- Bonnie L. Bassler7
- Yongna Xing6
- Yu Chen5
- Alicia A. Russo4
- Brenda A. Schulman4
- J. Wade Harper4
- Jong W. Yu4
- Yanhui Xu4
- Zhu Li4
- Abhishek Biswas3
- Dimitar B. Nikolov3
- Jeffry B. Stock3
- Liang Feng3
- Min Hu3
- Mohamed S. Donia3
- Ning Zheng3
- Rab K. Prinjha3
- William A. Barton3
- Zheng Lin3
- Adam Oberstein2
- Amanda Johns2
全論文
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
著者: Mark A. Dawson, Rab K. Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C. Robson, Chun‐wa Chung, Carsten Hopf, Mikhail M. Savitski, Carola Huthmacher, Emma Gudgin, Dave Lugo, Sören Beinke, Trevor Chapman, Emma J. Roberts, Peter E. Soden, Kurt R. Auger, Olivier Mirguet, Konstanze Doehner, Ruud Delwel, Alan K. Burnett, Philip D. Jeffrey, Gerard Drewes, Kevin Lee, Brian J.P. Huntly, Tony Kouzarides - Nature 2011 被引用: 1,532
- Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex
著者: Ning Zheng, Brenda A. Schulman, Langzhou Song, Julie J. Miller, Philip D. Jeffrey, Ping Wang, Claire Chu, Deanna M. Koepp, Stephen J. Elledge, Michele Pagano, Ronald Conaway, Joan Conaway, J. Wade Harper, Nikola P. Pavletich - Nature 2002 被引用: 1,522
- Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
著者: Shiqing Li, Karl R. Schmitz, Philip D. Jeffrey, J.J.W. Wiltzius, Paul Kussie, Kathryn M. Ferguson - Cancer Cell 2005 被引用: 1,107
- Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
著者: Yunje Cho, Svetlana S. Gorina, Philip D. Jeffrey, Nikola P. Pavletich - Science 1994 被引用: 2,542
- A metagenomic strategy for harnessing the chemical repertoire of the human microbiome
著者: Yuki Sugimoto, Francine R. Camacho, Shuo Wang, Pranatchareeya Chankhamjon, Arman Odabas, Abhishek Biswas, Philip D. Jeffrey, Mohamed S. Donia - Science 2019 被引用: 148
- The structural basis of Rubisco phase separation in the pyrenoid
著者: Shan He, Hui‐Ting Chou, Doreen Matthies, Tobias Wunder, Moritz T. Meyer, Nicky Atkinson, Antonio Martínez-Sánchez, Philip D. Jeffrey, Sarah A. Port, Weronika Patena, Guanhua He, Vivian K. Chen, Frederick M. Hughson, Alistair J. McCormick, Oliver Mueller‐Cajar, Benjamin D. Engel, Zhiheng Yu, Martin C. Jonikas - Nature Plants 2020 被引用: 146
- A Strategy for Antagonizing Quorum Sensing
著者: Guozhou Chen, Lee R. Swem, Danielle L. Swem, Devin L. Stauff, Colleen T. O’Loughlin, Philip D. Jeffrey, Bonnie L. Bassler, Frederick M. Hughson - Molecular Cell 2011 被引用: 308
- A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
著者: Richard W. Baker, Philip D. Jeffrey, Michael Zick, Ben P. Phillips, William Wickner, Frederick M. Hughson - Science 2015 被引用: 329
- Structure of a β-TrCP1-Skp1-β-Catenin Complex
著者: Geng Wu, Guozhou Xu, Brenda A. Schulman, Philip D. Jeffrey, J. Wade Harper, Nikola P. Pavletich - Molecular Cell 2003 被引用: 608
- Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
著者: Philip D. Jeffrey, Alicia A. Russo, Kornélia Polyák, E. Paul J. Gibbs, J Hurwitz, Joan Massagué, Nikola P. Pavletich - Nature 1995 被引用: 1,434
- Structure and mechanisms of the proteasome‐associated deubiquitinating enzyme USP14
著者: Min Hu, Pingwei Li, Ling Song, Philip D. Jeffrey, Tatiana A Chenova, Keith D. Wilkinson, Robert E. Cohen, Yigong Shi - The EMBO Journal 2005 被引用: 431
- The human microbiome encodes resistance to the antidiabetic drug acarbose
著者: Jared N. Balaich, Michael Estrella, Guojun Wu, Philip D. Jeffrey, Abhishek Biswas, Liping Zhao, Alexei Korennykh, Mohamed S. Donia - Nature 2021 被引用: 88
- Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53–MDM2 Pathway
著者: Min Hu, Lichuan Gu, Muyang Li, Philip D. Jeffrey, Wei Gu, Yigong Shi - PLoS Biology 2006 被引用: 249
- Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex
著者: Alicia A. Russo, Philip D. Jeffrey, Andrea K. Patten, Joan Massagué, Nikola P. Pavletich - Nature 1996 被引用: 906
- Crystal Structure of the Tetramerization Domain of the p53 Tumor Suppressor at 1.7 Angstroms
著者: Philip D. Jeffrey, Svetlana S. Gorina, Nikola P. Pavletich - Science 1995 被引用: 553
- Mechanism of procaspase-8 activation by c-FLIP L
著者: Jong W. Yu, Philip D. Jeffrey, Yigong Shi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 被引用: 161
- Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production
著者: Isabelle R. Taylor, Jon E. Paczkowski, Philip D. Jeffrey, Brad R. Henke, Chari D. Smith, Bonnie L. Bassler - ACS Chemical Biology 2021 被引用: 65
- Development of a Lc–Ms/Ms Method for the Quantification of Toxic Payload Dm1 Cleaved from Bt1718 in a Phase I Study
著者: Catherine Gowland, Philip Berry, Julie Errington, Philip D. Jeffrey, Gavin Bennett, Lisa Godfrey, Marc Pittman, Andrew Niewiarowski, Stefan N. Symeonides, Gareth J. Veal - Bioanalysis 2021 被引用: 33
- Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation
著者: Cristina R. Antonescu, Peter Besmer, Tianhua Guo, Knarik Arkun, Glory Hom, Beata Koryotowski, Margaret Leversha, Philip D. Jeffrey, Diann DeSantis, Samuel Singer, Murray F. Brennan, Robert G. Maki, Ronald P. DeMatteo - Clinical Cancer Research 2005 被引用: 831
- Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex
著者: Brenda A. Schulman, Andrea C. Carrano, Philip D. Jeffrey, Zachary H. Bowen, E. Kinnucan, Michael S. Finnin, Stephen J. Elledge, J. Wade Harper, Michele Pagano, Nikola P. Pavletich - Nature 2000 被引用: 609
- Structural basis of cyclin-dependent kinase activation by phosphorylation
著者: Alicia A. Russo, Philip D. Jeffrey, Nikola P. Pavletich - Nature Structural & Molecular Biology 1996 被引用: 594
- Crystal Structure of the Bcl-XL-Beclin 1 Peptide Complex
著者: Adam Oberstein, Philip D. Jeffrey, Yigong Shi - Journal of Biological Chemistry 2007 被引用: 560
- Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms
著者: Yan Xu, Liang Feng, Philip D. Jeffrey, Yigong Shi, François M. M. Morel - Nature 2008 被引用: 550
- Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
著者: Yongna Xing, Yanhui Xu, Yu Chen, Philip D. Jeffrey, Chao Yang, Zheng Lin, Zhu Li, Stefan Strack, Jeffry B. Stock, Yigong Shi - Cell 2006 被引用: 339
