Simon J. Boulton
1995–2026 年に発表
- 114
- 論文数
- 21,729
- 被引用数
- 79
- h 指数
- 112
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology69.1%
- Medicine25.1%
- Immunology and Microbiology1.8%
- Agricultural and Biological Sciences1%
- Energy0.7%
- Chemistry0.4%
- その他1.9%
トピック
- DNA Repair Mechanisms18%
- CRISPR and Genetic Engineering7.7%
- PARP inhibition in cancer therapy6.8%
- Genomics and Chromatin Dynamics4.1%
- Telomeres, Telomerase, and Senescence2.6%
- Microtubule and mitosis dynamics2.4%
- その他58.4%
共著者
- Graeme Hewitt12
- Roberto Bellelli12
- Stephen C. West12
- Valérie Borel12
- Jordan D. Ward11
- Julie S. Martin10
- Mark I.R. Petalcorin10
- Mark Skehel10
- Ondrej Beláň10
- Jillian L. Youds8
- David Rueda7
- Grzegorz Sarek7
- Jean‐Baptiste Vannier7
- Louise J. Barber7
- Marc Vidal7
- Sandra Segura‐Bayona7
- Spencer J. Collis7
- Zuzana Hořejšı́7
- Helen R. Flynn6
- Roopesh Anand6
- Aleksandra Vančevska5
- Anton Gartner5
- J. Ross Chapman5
- Matthew D. Newton5
全論文
- Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
著者: Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert A. Heald, Sophie Langdon, Jayesh B. Majithiya, Claire McWhirter, Niall M.B. Martin, Shaun Moore, Joana Neves, Eeson Rajendra, Marco Ranzani, Theresia A. Schaedler, Martin L. Stockley, Kimberley A. Wiggins, Rachel Brough, Sandhya Sridhar, Aditi Gulati, Nan Shao, Luned Badder, Daniela Novo, Eleanor Knight, Rebecca Marlow, Syed Haider, Elsa Callén, Graeme Hewitt, Joost Schimmel, Remko Prevo, Christina Alli, Amanda Ferdinand, Cameron Bell, Peter Blencowe, Christopher Bot, Mathew Calder, Mark Charles, Jayne Curry, Tennyson Ekwuru, Katherine Ewings, Wojciech Krajewski, Ellen MacDonald, Hollie McCarron, Leon Pang, Chris Pedder, Laurent Rigoreau, Martin E. Swarbrick, Ed Wheatley, Simon N. Willis, Ai Ching Wong, André Nussenzweig, Marcel Tijsterman, Andrew Tutt, Simon J. Boulton, Geoff S. Higgins, Stephen J. Pettitt, Graeme C.M. Smith, Christopher J. Lord - Nature Communications 2021 被引用: 350
- Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
著者: Raphaël Ceccaldi, Jessie Liu, Ravindra Amunugama, Ildikó Hajdú, Benjamin Primack, Mark I.R. Petalcorin, Kevin W. O’Connor, Panagiotis A. Konstantinopoulos, Stephen J. Elledge, Simon J. Boulton, Timur Yusufzai, Alan D. D’Andrea - Nature 2015 被引用: 901
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
著者: J. Ross Chapman, Martin R.G. Taylor, Simon J. Boulton - Molecular Cell 2012 被引用: 1,640
- Double-strand break repair: 53BP1 comes into focus
著者: Stephanie Panier, Simon J. Boulton - Nature Reviews Molecular Cell Biology 2013 被引用: 1,116
- POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
著者: Ondrej Beláň, Marie Sebald, Marek Adamowicz, Roopesh Anand, Aleksandra Vančevska, Joana Neves, Vera Grinkevich, Graeme Hewitt, Sandra Segura‐Bayona, Roberto Bellelli, Helen M.R. Robinson, Geoff S. Higgins, Graeme C.M. Smith, Stephen C. West, David Rueda, Simon J. Boulton - Molecular Cell 2022 被引用: 129
- Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place
著者: Panagiotis Kotsantis, Eva Petermann, Simon J. Boulton - Cancer Discovery 2018 被引用: 419
- Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
著者: Graeme Hewitt, Valérie Borel, Sandra Segura‐Bayona, Tohru Takaki, Phil Ruis, Roberto Bellelli, Laura C. Lehmann, Lucia Sommerová, Aleksandra Vančevska, Antonia Tomás‐Loba, Kang Zhu, C.D.O. Cooper, Kasper Fugger, Harshil Patel, Robert Goldstone, Deborah Schneider-Luftman, Ellie Herbert, Gordon Stamp, Rachel Brough, Stephen J. Pettitt, Christopher J. Lord, Stephen C. West, Ivan Ahel, Dragana Ahel, J. Ross Chapman, Sebastian Deindl, Simon J. Boulton - Molecular Cell 2020 被引用: 164
- REV7 counteracts DNA double-strand break resection and affects PARP inhibition
著者: Guotai Xu, J. Ross Chapman, Inger Brandsma, Jingsong Yuan, Martin Mistrík, Peter Bouwman, Jiřina Bártková, Ewa Gogola, Daniël O. Warmerdam, Marco Barazas, Janneke E. Jaspers, Kenji Watanabe, Mark Pieterse, Ariena Kersbergen, Wendy Sol, Patrick H. N. Celie, Philip C. Schouten, Bram van den Broek, Ahmed Salman, Marja Nieuwland, Iris de Rink, Jorma de Ronde, Kees Jalink, Simon J. Boulton, Junjie Chen, Dik C. van Gent, Jiří Bártek, Jos Jonkers, Piet Borst, Sven Rottenberg - Nature 2015 被引用: 602
- Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution
著者: Subramanian Venkatesan, Mihaela Angelova, Clare Puttick, Hao-Ran Zhai, Deborah R. Caswell, Wei-Ting Lu, Michelle Dietzen, Panagiotis Galanos, Konstantinos Evangelou, Roberto Bellelli, Emilia L. Lim, Thomas B.K. Watkins, Andrew Rowan, Vitor H. Teixeira, Yue Zhao, Haiquan Chen, Bryan Ngo, Lykourgos‐Panagiotis Zalmas, Maise Al Bakir, Sebastijan Hobor, Eva Grönroos, Adam Pennycuick, Ersilia Nigro, Brittany Campbell, William L. Brown, Ayse U. Akarca, Teresa Marafioti, Mary Wu, Michael Howell, Simon J. Boulton, Cosetta Bertoli, Tim R. Fenton, Robertus A.M. de Bruin, Apolinar Maya‐Mendoza, Eric Santoni‐Rugiu, Robert E. Hynds, Vassilis G. Gorgoulis, Mariam Jamal‐Hanjani, Nicholas McGranahan, Reuben S. Harris, Sam M. Janes, Jiřina Bártková, Samuel F. Bakhoum, Jiří Bártek, Nnennaya Kanu, Charles Swanton - Cancer Discovery 2021 被引用: 143
- Mechanisms of DNA–protein crosslink repair
著者: Julian Stingele, Roberto Bellelli, Simon J. Boulton - Nature Reviews Molecular Cell Biology 2017 被引用: 298
- Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1
著者: Dragana Ahel, Zuzana Hořejšı́, Nicola Wiechens, Sophie E. Polo, Elisa Garcia-Wilson, Ivan Ahel, Helen R. Flynn, Mark Skehel, Stephen C. West, Stephen P. Jackson, Tom Owen‐Hughes, Simon J. Boulton - Science 2009 被引用: 600
- Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA -deficient cells to PARP inhibitors
著者: Kasper Fugger, Ilirjana Bajrami, Mariana Silva dos Santos, Sarah Jane Young, Simone Kunzelmann, Geoff Kelly, Graeme Hewitt, Harshil Patel, Robert Goldstone, Thomas Carell, Simon J. Boulton, James I. MacRae, Ian A. Taylor, Stephen C. West - Science 2021 被引用: 134
- Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN
著者: Julian Stingele, Roberto Bellelli, Ferdinand Alte, Graeme Hewitt, Grzegorz Sarek, Sarah Maslen, Susan E. Tsutakawa, Annabel Borg, Svend Kjær, John A. Tainer, Mark Skehel, M. Groll, Simon J. Boulton - Molecular Cell 2016 被引用: 248
- Micronuclei induced by radiation, replication stress, or chromosome segregation errors do not activate cGAS-STING
著者: Tohru Takaki, Rhona Millar, Crispin T. Hiley, Simon J. Boulton - Molecular Cell 2024 被引用: 79
- Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
著者: Ivan Ahel, Dragana Ahel, Takahiro Matsusaka, Allison J. Clark, Jonathon Pines, Simon J. Boulton, Stephen C. West - Nature 2008 被引用: 425
- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
著者: Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara García-Gómez, Marija Marić, Marco Tognetti, Christopher Benner, Simon J. Boulton, Alan Saghatelian, Jan Karlseder - Nature 2017 被引用: 299
- Moving From Poly (ADP-Ribose) Polymerase Inhibition to Targeting DNA Repair and DNA Damage Response in Cancer Therapy
著者: Charlie Gourley, Judith Balmañà, Jonathan A. Ledermann, Violeta Serra, Rebecca Dent, Sibylle Loibl, Éric Pujade-Lauraine, Simon J. Boulton - Journal of Clinical Oncology 2019 被引用: 198
- POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
著者: Roberto Bellelli, Ondrej Beláň, Valerie E. Pye, Camille Clément, Sarah Maslen, Mark Skehel, Peter Cherepanov, Geneviève Almouzni, Simon J. Boulton - Molecular Cell 2018 被引用: 138
- BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks
著者: Martin R. Higgs, John J. Reynolds, Alicja Winczura, Andrew N. Blackford, Valérie Borel, Edward S. Miller, Anastasia Zlatanou, Jadwiga Nieminuszczy, Ellis L. Ryan, Nicholas Davies, Tatjana Stanković, Simon J. Boulton, Wojciech Niedźwiedź, Grant S. Stewart - Molecular Cell 2015 被引用: 209
- Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis
著者: Anna R. Poetsch, Simon J. Boulton, Nicholas M. Luscombe - Genome biology 2018 被引用: 137
- Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology
著者: Oliver J. Ziff, Jacob Neeves, Jamie S. Mitchell, Giulia E. Tyzack, Carlos Martínez‐Ruiz, Raphaëlle Luisier, Anob M. Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J. Boulton, Ammar Al‐Chalabi, Gavin Kelly, Jack Humphrey, Rickie Patani - Nature Communications 2023 被引用: 61
- Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways
著者: Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, Robin van Schendel, Sven van der Vlies, Juliette A. Kamp, Femke M.S. de Vrij, Steven A. Kushner, Graeme C.M. Smith, Simon J. Boulton, Marcel Tijsterman - Cell Reports 2023 被引用: 73
- RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
著者: J. Ross Chapman, Patricia Barral, Jean‐Baptiste Vannier, Valérie Borel, Martin Steger, Antonia Tomás‐Loba, Alessandro A. Sartori, Ian R. Adams, Facundo D. Batista, Simon J. Boulton - Molecular Cell 2013 被引用: 629
- Structure and function of the RAD51B–RAD51C–RAD51D–XRCC2 tumour suppressor
著者: Luke A. Greenhough, Chih‐Chao Liang, Ondrej Beláň, Simone Kunzelmann, Sarah Maslen, Monica C. Rodrigo-Brenni, Roopesh Anand, Mark Skehel, Simon J. Boulton, Stephen C. West - Nature 2023 被引用: 81
