Alan Saghatelian
Active 2001–2025
- 111
- Papers
- 20,614
- Citations
- 79
- h-index
- 105
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology50.6%
- Medicine26.4%
- Neuroscience6.1%
- Immunology and Microbiology4.8%
- Chemistry4.8%
- Agricultural and Biological Sciences2.2%
- Other5.1%
Topics
- RNA modifications and cancer2.7%
- Metabolomics and Mass Spectrometry Studies2.6%
- Cancer, Hypoxia, and Metabolism2.6%
- RNA and protein synthesis mechanisms2.3%
- Gut microbiota and health2%
- Cancer-related molecular mechanisms research1.8%
- Other86%
Coauthors
- Antônio F. M. Pinto19
- Benjamin F. Cravatt16
- Cynthia J. Donaldson14
- Joan Vaughan14
- Barbara B. Kahn13
- Matthew J. Kolar13
- Jolene K. Diedrich11
- Qian Chu10
- Dionicio Siegel9
- Thomas F. Martínez9
- Dan Tan8
- Jiao Ma8
- Eduardo Vieira de Souza6
- Edwin A. Homan6
- Ismail Syed6
- M. Reza Ghadiri6
- Pedro M. Moraes‐Vieira6
- Amanda McFedries5
- Andrew T. Nelson5
- Satchidananda Panda5
- Srihari Konduri5
- Adam G. Schwaid4
- Amandine Chaix4
- Bogdan Budnik4
All papers
- Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis
Authors: Peiwen Chen, Hao Zuo, Hu Xiong, Matthew J. Kolar, Qian Chu, Alan Saghatelian, Daniel J. Siegwart, Yihong Wan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 505
- How many human proteoforms are there?
Authors: Ruedi Aebersold, Jeffrey N. Agar, I. Jonathan Amster, Mark S. Baker, Carolyn R. Bertozzi, Emily S. Boja, Catherine E. Costello, Benjamin F. Cravatt, Catherine Fenselau, Benjamin A. García, Ying Ge, Jeremy Gunawardena, Ronald C. Hendrickson, Paul J. Hergenrother, Christian G. Huber, Alexander R. Ivanov, Ole N. Jensen, Michael C. Jewett, Neil L. Kelleher, Laura L. Kiessling, Nevan J. Krogan, Martin R. Larsen, Joseph A. Loo, Rachel R. Ogorzalek Loo, Emma Lundberg, Michael J. MacCoss, Parag Mallick, Vamsi K. Mootha, Milan Mrksich, Tom W. Muir, Steven M. Patrie, James J. Pesavento, Sharon J. Pitteri, Henry Rodriguez, Alan Saghatelian, Wendy Sandoval, Hartmut Schlüter, Salvatore Sechi, Sarah A. Slavoff, Lloyd M. Smith, M Snyder, Paul M. Thomas, Mathias Uhlén, Jennifer E. Van Eyk, Marc Vidal, David R. Walt, Forest M. White, Evan R. Williams, Therese Wohlschlager, Vicki H. Wysocki, Nathan A. Yates, Nicolas L. Young, Bing Zhang - Nature Chemical Biology 2018 cited by 944
- Serine restriction alters sphingolipid diversity to constrain tumour growth
Authors: Thangaselvam Muthusamy, Thekla Cordes, Michal K. Handzlik, Le You, Esther W. Lim, Jivani M. Gengatharan, Antônio F. M. Pinto, Mehmet G. Badur, Matthew J. Kolar, Martina Wallace, Alan Saghatelian, Christian M. Metallo - Nature 2020 cited by 314
- Standardized annotation of translated open reading frames
Authors: Jonathan M. Mudge, Jorge Ruiz‐Orera, John R. Prensner, Marie A. Brunet, Ferriol Calvet, Irwin Jungreis, José M. González, Michele Magrane, Thomas F. Martínez, Jana Felicitas Schulz, Yucheng Yang, M. Mar Albà, Julie L. Aspden, Pavel V. Baranov, Ariel Bazzini, Elspeth A. Bruford, María Martin, Lorenzo Calviello, Anne‐Ruxandra Carvunis, Jin Chen, Juan Pablo Couso, Eric W. Deutsch, Paul Flicek, Adam Frankish, Mark Gerstein, Norbert Hübner, Nicholas T. Ingolia, Manolis Kellis, Gerben Menschaert, Robert L. Moritz, Uwe Ohler, Xavier Roucou, Alan Saghatelian, Jonathan S. Weissman, Sebastiaan van Heesch - Nature Biotechnology 2022 cited by 250
- Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
Authors: Robert Svensson, Seth J. Parker, Lillian J. Eichner, Matthew J. Kolar, Martina Wallace, Sonja N. Brun, Portia S. Lombardo, Jeanine L. Van Nostrand, Amanda Hutchins, Lilliana Vera, Laurie Gerken, Jeremy R. Greenwood, Sathesh Bhat, Geraldine Harriman, William Westlin, H. James Harwood, Alan Saghatelian, Rosana Kapeller, Christian M. Metallo, Reuben J. Shaw - Nature Medicine 2016 cited by 520
- Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism
Authors: Amir Zarrinpar, Amandine Chaix, Zhenjiang Zech Xu, Max W. Chang, Clarisse Marotz, Alan Saghatelian, Rob Knight, Satchidananda Panda - Nature Communications 2018 cited by 540
- Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
Authors: Mark M. Yore, Ismail Syed, Pedro M. Moraes‐Vieira, Tejia Zhang, Mark A. Herman, Edwin A. Homan, Rajesh T. Patel, Jennifer Lee, Shili Chen, Odile D. Peroni, Abha S. Dhaneshwar, Ann Hammarstedt, Ulf Smith, Timothy E. McGraw, Alan Saghatelian, Barbara B. Kahn - Cell 2014 cited by 844
- The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
Authors: R Chin, Xudong Fu, Melody Y. Pai, Laurent Vergnes, Heejun Hwang, Gang Deng, Simon Diep, Brett Lomenick, Vijaykumar S. Meli, Gabriela C. Monsalve, Eileen Hu, Stephen A. Whelan, Jennifer X. Wang, Gwanghyun Jung, Gregory M. Solis, Farbod Fazlollahi, Chitrada Kaweeteerawat, Austin Quach, Mahta Nili, Abby S. Krall, Hilary A. Godwin, Helena R. Chang, Kym F. Faull, Feng Guo, Meisheng Jiang, Sunia A. Trauger, Alan Saghatelian, Daniel Braas, Heather R. Christofk, Catherine F. Clarke, Michael A. Teitell, Michael Petrascheck, Karen Reue, Michael E. Jung, Alison R. Frand, Jing Huang - Nature 2014 cited by 623
- Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
Authors: Jessica J. Howell, Kristina Hellberg, Marc Turner, George Talbott, Matthew J. Kolar, Debbie S. Ross, Gerta Hoxhaj, Alan Saghatelian, Reuben J. Shaw, Brendan D. Manning - Cell Metabolism 2017 cited by 405
- mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide
Authors: Akinobu Matsumoto, Alessandra Pasut, Masaki Matsumoto, Riu Yamashita, Jacqueline Fung, Emanuele Monteleone, Alan Saghatelian, Keiichi I. Nakayama, John G. Clohessy, Pier Paolo Pandolfi - Nature 2016 cited by 652
- Peptidomic discovery of short open reading frame–encoded peptides in human cells
Authors: Sarah A. Slavoff, Andrew J. Mitchell, Adam G. Schwaid, Moran N. Cabili, Jiao Ma, Joshua Z. Levin, Amir Karger, Bogdan Budnik, John L. Rinn, Alan Saghatelian - Nature Chemical Biology 2012 cited by 686
- Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes
Authors: Baylee J. Russell, Steven D. Brown, Nicole Siguenza, Irene Mai, Anand Saran, Amulya Lingaraju, Erica S. Maissy, Ana Carolina Dantas Machado, Antônio F. M. Pinto, Concepcion Sanchez, Leigh‐Ana Rossitto, Yukiko Miyamoto, R. Alexander Richter, Samuel B. Ho, Lars Eckmann, Jeff Hasty, David J. Gonzalez, Alan Saghatelian, Rob Knight, Amir Zarrinpar - Cell 2022 cited by 147
- SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism
Authors: Yumiko Oishi, Nathanael J. Spann, Verena M. Link, Evan D. Muse, Tobias Strid, Chantle Edillor, Matthew J. Kolar, Takashi Matsuzaka, Sumio Hayakawa, Jenhan Tao, Minna U. Kaikkonen, Aaron F. Carlin, Michael T. Lam, Ichiro Manabe, Hitoshi Shimano, Alan Saghatelian, Christopher K. Glass - Cell Metabolism 2016 cited by 342
- Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD
Authors: Daniel Garcia, Kristina Hellberg, Amandine Chaix, Martina Wallace, Sébastien Herzig, Mehmet G. Badur, Terry Lin, Maxim N. Shokhirev, Antônio F. M. Pinto, Debbie S. Ross, Alan Saghatelian, Satchidananda Panda, Lukas E. Dow, Christian M. Metallo, Reuben J. Shaw - Cell Reports 2019 cited by 302
- Proteomic discovery of chemical probes that perturb protein complexes in human cells
Authors: Michael R. Lazear, Jarrett R. Remsberg, Martin G. Jaeger, Katherine Rothamel, Hsuan-Lin Her, Kristen E. DeMeester, Evert Njomen, Simon J. Hogg, Jahan Rahman, Landon R. Whitby, Sang Joon Won, Michael A. Schafroth, Daisuke Ogasawara, Minoru Yokoyama, Garrett L. Lindsey, Haoxin Li, Jason Germain, Sabrina Barbas, Joan Vaughan, Thomas W. Hanigan, Vincent F. Vartabedian, Christopher J. Reinhardt, Melissa M. Dix, Seong Joo Koo, Inha Heo, John R. Teijaro, Gabriel M. Simon, B.K. Ghosh, Omar Abdel‐Wahab, Kay Ahn, Alan Saghatelian, Bruno Melillo, Stuart L. Schreiber, G Yeo, Benjamin F. Cravatt - Molecular Cell 2023 cited by 93
- Accurate annotation of human protein-coding small open reading frames
Authors: Thomas F. Martínez, Qian Chu, Cynthia J. Donaldson, Dan Tan, Maxim N. Shokhirev, Alan Saghatelian - Nature Chemical Biology 2019 cited by 260
- Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence
Authors: Gabriele Sulli, Amy Rommel, Xiaojie Wang, Matthew J. Kolar, Francesca Puca, Alan Saghatelian, Maksim V. Plikus, Inder M. Verma, Satchidananda Panda - Nature 2018 cited by 410
- ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
Authors: Rucha Patel, Anna Santoro, Peter Hofer, Dan Tan, Monika Oberer, Andrew T. Nelson, Srihari Konduri, Dionicio Siegel, Rudolf Zechner, Alan Saghatelian, Barbara B. Kahn - Nature 2022 cited by 128
- Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome
Authors: Ana Carolina Dantas Machado, Steven D. Brown, Amulya Lingaraju, Vignesh Sivaganesh, Cameron Martino, Amandine Chaix, Peng Zhao, Antônio F. M. Pinto, Max W. Chang, R. Alexander Richter, Alan Saghatelian, Alan R. Saltiel, Rob Knight, Satchidananda Panda, Amir Zarrinpar - Cell Reports 2022 cited by 107
- Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors
Authors: Andrea Pauli, Megan L. Norris, Eivind Valen, Guo-Liang Chew, James A. Gagnon, Steven Zimmerman, Andrew Mitchell, Jiao Ma, Julien Dubrulle, Deepak Reyon, Shengdar Q. Tsai, J. Keith Joung, Alan Saghatelian, Alexander F. Schier - Science 2014 cited by 642
- A human microprotein that interacts with the mRNA decapping complex
Authors: Nadia G. D’Lima, Jiao Ma, Lauren Winkler, Qian Chu, Ken H. Loh, Elizabeth O. Corpuz, Bogdan Budnik, Jens Lykke‐Andersen, Alan Saghatelian, Sarah A. Slavoff - Nature Chemical Biology 2016 cited by 317
- FGF1 and insulin control lipolysis by convergent pathways
Authors: Gencer Sancar, Sihao Liu, Emanuel Gasser, Jacqueline G. Alvarez, Christopher P. Moutos, Kyeongkyu Kim, Tim van Zutphen, Yuhao Wang, Timothy F. Huddy, Brittany N. Ross, Yang Dai, David Zepeda, Brett Collins, Emma Tilley, Matthew J. Kolar, Ruth T. Yu, Annette R. Atkins, Theo H. van Dijk, Alan Saghatelian, Johan W. Jonker, Michael Downes, Ronald M. Evans - Cell Metabolism 2022 cited by 111
- Profiling mouse brown and white adipocytes to identify metabolically relevant small ORFs and functional microproteins
Authors: Thomas F. Martínez, Sally Lyons‐Abbott, Angie L. Bookout, Eduardo Vieira de Souza, Cynthia J. Donaldson, Joan Vaughan, Calvin J. Lau, Ariel Abramov, Arian F. Baquero, Karalee Baquero, Dave Friedrich, Justin Huard, Ray Davis, Bong-Chul Kim, Ty Koch, Aaron J. Mercer, Ayesha Misquith, Sara A. Murray, Sakara Perry, Lindsay K. Pino, Christina A. Sanford, Alex Simon, Yu Zhang, Garrett Zipp, Cristiano Valim Bizarro, Maxim N. Shokhirev, Andrew J. Whittle, Brian C. Searle, Michael J. MacCoss, Alan Saghatelian, Christopher A. Barnes - Cell Metabolism 2023 cited by 78
- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
Authors: Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara García-Gómez, Marija Marić, Marco Tognetti, Christopher Benner, Simon J. Boulton, Alan Saghatelian, Jan Karlseder - Nature 2017 cited by 299
