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Ann–Hwee Lee

Active 1998–2024

Also published as
Ann-Hwee Lee · Ann Hwee Lee · Ann- Hwee Lee
45
Papers
19,700
Citations
41
h-index
45
i10-index

Citations

Citations per year for Ann–Hwee Lee1983: 1 citations1994: 1 citations1996: 1 citations1999: 3 citations2000: 3 citations2001: 1 citations2002: 2 citations2003: 16 citations2004: 52 citations2005: 130 citations2006: 186 citations2007: 240 citations2008: 220 citations2009: 357 citations2010: 383 citations2011: 387 citations2012: 445 citations2013: 363 citations2014: 411 citations2015: 328 citations2016: 316 citations2017: 348 citations2018: 321 citations2019: 844 citations2020: 776 citations2021: 769 citations2022: 588 citations2023: 383 citations2024: 577 citations2025: 278 citations2026: 6 citations1984–1993: no citations, so these years are not shown1995: no citations, so this year is not shown1997–1998: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,875 citing papers, 31.5% of this breakdownChina: 1,281 citing papers, 14.1% of this breakdownUnited Kingdom: 481 citing papers, 5.3% of this breakdownGermany: 412 citing papers, 4.5% of this breakdownJapan: 359 citing papers, 3.9% of this breakdownCanada: 310 citing papers, 3.4% of this breakdownFrance: 288 citing papers, 3.2% of this breakdownItaly: 255 citing papers, 2.8% of this breakdownSouth Korea: 244 citing papers, 2.7% of this breakdownAustralia: 229 citing papers, 2.5% of this breakdownSpain: 195 citing papers, 2.1% of this breakdownNetherlands: 171 citing papers, 1.9% of this breakdown
0%31.5%Other 22.1%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology54.9%
  • Medicine30.8%
  • Immunology and Microbiology8.6%
  • Neuroscience2.1%
  • Nursing1%
  • Agricultural and Biological Sciences0.9%
  • Other1.7%

Topics

  • Endoplasmic Reticulum Stress and Disease14.6%
  • Autophagy in Disease and Therapy6.3%
  • Pancreatic function and diabetes4.4%
  • Adipose Tissue and Metabolism3.1%
  • Liver Disease Diagnosis and Treatment2.9%
  • Immune Cell Function and Interaction2.4%
  • Other66.3%

Coauthors

All papers

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  1. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

    Authors: Juan R. Cubillos‐Ruiz, Pedro C. Silberman, Melanie R. Rutkowski, Sahil Chopra, Alfredo Perales‐Puchalt, Minkyung Song, Sheng Zhang, Sarah E. Bettigole, Divya Gupta, Kevin Holcomb, Lora H. Ellenson, Thomas A. Caputo, Ann–Hwee Lee, José R. Conejo-García, Laurie H. Glimcher - Cell 2015 cited by 951

  2. Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

    Authors: Umut Özcan, Qiong Cao, Erkan Yılmaz, Ann–Hwee Lee, Neal N. Iwakoshi, Esra Özdelen, Gürol Tuncman, Cem Z. Görgün, Laurie H. Glimcher, Gökhan S. Hotamışlıgil - Science 2004 cited by 3,852

  3. XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

    Authors: Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher - Molecular and Cellular Biology 2003 cited by 2,057

  4. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

    Authors: Fabio Martinon, Xi Chen, Ann–Hwee Lee, Laurie H. Glimcher - Nature Immunology 2010 cited by 990

  5. XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

    Authors: Arthur Kaser, Ann–Hwee Lee, André Franke, Jonathan N. Glickman, Sebastian Zeißig, Herbert Tilg, Edward E. S. Nieuwenhuis, Darren E. Higgins, Stefan Schreiber, Laurie H. Glimcher, Richard S. Blumberg - Cell 2008 cited by 1,402

  6. Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

    Authors: Ann–Hwee Lee, Erez Scapa, David E. Cohen, Laurie H. Glimcher - Science 2008 cited by 978

  7. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation

    Authors: Shengyi Sun, Guojun Shi, Haibo Sha, Yewei Ji, Xuemei Han, Xin Shu, Hongming Ma, Takamasa Inoue, Beixue Gao, Hana Kim, Pengcheng Bu, Robert D. Guber, Xiling Shen, Ann-Hwee Lee, Takao Iwawaki, Adrienne W. Paton, James C. Paton, Deyu Fang, Billy Tsai, John R. Yates, Haoquan Wu, Sander Kersten, Qiaoming Long, G Duhamel, Kenneth W. Simpson, Ling Qi - Nature Cell Biology 2015 cited by 257

  8. Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway

    Authors: Zhao V. Wang, Yingfeng Deng, Ningguo Gao, Zully Pedrozo, Dan L. Li, Cyndi R. Morales, Alfredo Criollo, Xiang Luo, Wei Tan, Nan Jiang, Mark A. Lehrman, Beverly A. Rothermel, Ann-Hwee Lee, Sergio Lavandero, Pradeep P.A. Mammen, Anwarul Ferdous, Thomas G. Gillette, Philipp E. Scherer, Joseph A. Hill - Cell 2014 cited by 412

  9. Silencing of Lipid Metabolism Genes through IRE1α-Mediated mRNA Decay Lowers Plasma Lipids in Mice

    Authors: Jae‐Seon So, Kyu Yeon Hur, Margarite L. Tarrio, Vera M. Ruda, Maria Frank-Kamenetsky, Kevin Fitzgerald, Victor Koteliansky, Andrew H. Lichtman, Takao Iwawaki, Laurie H. Glimcher, Ann–Hwee Lee - Cell Metabolism 2012 cited by 270

  10. XBP1, Downstream of Blimp-1, Expands the Secretory Apparatus and Other Organelles, and Increases Protein Synthesis in Plasma Cell Differentiation

    Authors: Arthur L. Shaffer, Miriam A. Shelef, Neal N. Iwakoshi, Ann–Hwee Lee, Shu‐Bing Qian, Hong Zhao, Xin Yu, Liming Yang, Bruce K. Tan, Andreas Rosenwald, Elaine M. Hurt, Emmanuel Petroulakis, Nahum Sonenberg, Jonathan W. Yewdell, Kathryn Calame, Laurie H. Glimcher, Louis M. Staudt - Immunity 2004 cited by 1,040

  11. Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP

    Authors: Xu Xu, Jae‐Seon So, Jong‐Gil Park, Ann–Hwee Lee - Seminars in Liver Disease 2013 cited by 292

  12. The endoplasmic reticulum stress response in immunity and autoimmunity

    Authors: Derrick J. Todd, Ann–Hwee Lee, Laurie H. Glimcher - Nature reviews. Immunology 2008 cited by 618

  13. Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response

    Authors: Yurong Xin, Giselle Domínguez Gutiérrez, Haruka Okamoto, Jinrang Kim, Ann–Hwee Lee, Christina Adler, Min Ni, George D. Yancopoulos, Andrew Murphy, Jesper Gromada - Diabetes 2018 cited by 201

  14. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

    Authors: Neal N. Iwakoshi, Ann–Hwee Lee, Prasanth Vallabhajosyula, Kevin L. Otipoby, Klaus Rajewsky, Laurie H. Glimcher - Nature Immunology 2003 cited by 866

  15. Dual and opposing roles of the unfolded protein response regulated by IRE1α and XBP1 in proinsulin processing and insulin secretion

    Authors: Ann–Hwee Lee, Keely Heidtman, Gökhan S. Hotamışlıgil, Laurie H. Glimcher - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 270

  16. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

    Authors: Ann–Hwee Lee, Neal N. Iwakoshi, Kenneth C. Anderson, Laurie H. Glimcher - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 598

  17. The transcription factor XBP1 is selectively required for eosinophil differentiation

    Authors: Sarah E. Bettigole, Raphaël Lis, Stanley Adoro, Ann–Hwee Lee, Lisa A. Spencer, Peter F. Weller, Laurie H. Glimcher - Nature Immunology 2015 cited by 195

  18. XBP‐1 is required for biogenesis of cellular secretory machinery of exocrine glands

    Authors: Ann–Hwee Lee, Gerald C. Chu, Neal N. Iwakoshi, Laurie H. Glimcher - The EMBO Journal 2005 cited by 448

  19. Proapoptotic BAX and BAK Modulate the Unfolded Protein Response by a Direct Interaction with IRE1α

    Authors: Claudio Hetz, Paula Bernasconi, Jill K. Fisher, Ann–Hwee Lee, Michael C. Bassik, Bruno Antonsson, Gabriel S. Brandt, Neal N. Iwakoshi, Anna C. Schinzel, Laurie H. Glimcher, Stanley J. Korsmeyer - Science 2006 cited by 664

  20. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

    Authors: Derrick J. Todd, Louise J. McHeyzer‐Williams, Czeslawa Kowal, Ann–Hwee Lee, Bruce T. Volpe, Betty Diamond, Michael G. McHeyzer‐Williams, Laurie H. Glimcher - The Journal of Experimental Medicine 2009 cited by 235

  21. XBP1 Is Essential for Survival under Hypoxic Conditions and Is Required for Tumor Growth

    Authors: Lorenzo Romero‐Ramírez, Hongbin Cao, Daniel W. Nelson, Ester M. Hammond, Ann–Hwee Lee, Hiderou Yoshida, Kazutoshi Mori, Laurie H. Glimcher, Nicholas Denko, Amato J. Giaccia, Quynh‐Thu Le, Albert C. Koong - Cancer Research 2004 cited by 570

  22. The X‐box binding protein‐1 transcription factor is required for plasma cell differentiation and the unfolded protein response

    Authors: Neal N. Iwakoshi, Ann–Hwee Lee, Laurie H. Glimcher - Immunological Reviews 2003 cited by 268

  23. Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells

    Authors: Yang Hu, Kevin K. Park, Yang Liu, Xin Wei, Qiang Yang, Kin‐Sang Cho, Peter Thielen, Ann-Hwee Lee, Romain Cartoni, Laurie H. Glimcher, Dong Feng Chen, Zhigang He - Neuron 2012 cited by 209

  24. Transcriptional activation of Fsp27 by the liver‐enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis

    Authors: Xu Xu, Jong‐Gil Park, Jae‐Seon So, Ann–Hwee Lee - Hepatology 2014 cited by 101