Arian Laurence
Active 2006–2025
- 85
- Papers
- 23,805
- Citations
- 65
- h-index
- 83
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology39.8%
- Medicine38.7%
- Biochemistry, Genetics and Molecular Biology16.9%
- Neuroscience1.7%
- Dentistry0.5%
- Pharmacology, Toxicology and Pharmaceutics0.4%
- Other2%
Topics
- Immune Cell Function and Interaction8.4%
- T-cell and B-cell Immunology7.5%
- Psoriasis: Treatment and Pathogenesis5.3%
- Cytokine Signaling Pathways and Interactions4.5%
- Immunotherapy and Immune Responses3.2%
- IL-33, ST2, and ILC Pathways3.1%
- Other68%
Coauthors
- John J. O’Shea46
- Yuka Kanno22
- Hong‐Wei Sun14
- Xiang‐Ping Yang14
- Golnaz Vahedi11
- Kiyoshi Hirahara11
- Kamran Ghoreschi10
- Behdad Afzali9
- Alejandro V. Villarino8
- Holm H. Uhlig7
- Cristina M. Tato6
- Ethan M. Shevach6
- Jing Wang6
- Kan Jiang6
- Lai Wei6
- Lothar Hennighausen6
- Majid Kazemian6
- Xiang Cheng6
- Zhengping Wei6
- Claudia Kemper5
- Daniel Chauss5
- Daniella M. Schwartz5
- Giuseppe Sciumè5
- Huabin Li5
All papers
- The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
Authors: John J. O’Shea, Daniella M. Schwartz, Alejandro V. Villarino, Massimo Gadina, Iain B. McInnes, Arian Laurence - Annual Review of Medicine 2015 cited by 1,577
- Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression
Authors: Na Liu, Jing Luo, Dong Kuang, Sanpeng Xu, Yaqi Duan, Yu Xia, Zhengping Wei, Xiuxiu Xie, Bingjiao Yin, Fang Chen, Shunqun Luo, Huicheng Liu, Jing Wang, Kan Jiang, Feili Gong, Zhaohui Tang, Xiang Cheng, Huabin Li, Zhuoya Li, Arian Laurence, Guoping Wang, Xiang‐Ping Yang - Journal of Clinical Investigation 2018 cited by 244
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
Authors: Kamran Ghoreschi, Arian Laurence, Xiang‐Ping Yang, Cristina M. Tato, Mandy J. McGeachy, Joanne E. Konkel, Haydeé L. Ramos, Lai Wei, Todd S. Davidson, Nicolas Bouladoux, John R. Grainger, Qian Chen, Yuka Kanno, Wendy T. Watford, Hong‐Wei Sun, Gérard Eberl, Ethan M. Shevach, Yasmine Belkaid, Daniel J. Cua, Wanjun Chen, John J. O’Shea - Nature 2010 cited by 1,385
- Janus kinases in immune cell signaling
Authors: Kamran Ghoreschi, Arian Laurence, John J. O’Shea - Immunological Reviews 2009 cited by 1,141
- Selectivity, efficacy and safety of JAKinibs: new evidence for a still evolving story
Authors: Michael Bonelli, Andreas Kerschbaumer, Kastriot Kastrati, Kamran Ghoreschi, Massimo Gadina, Leonhard X. Heinz, Josef S Smolen, Daniel Aletaha, John J. O’Shea, Arian Laurence - Annals of the Rheumatic Diseases 2023 cited by 143
- Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
Authors: Arian Laurence, Cristina M. Tato, Todd S. Davidson, Yuka Kanno, Zhi Chen, Zhengju Yao, Rebecca B. Blank, Françoise Meylan, Richard M. Siegel, Lothar Hennighausen, Ethan M. Shevach, John J. O’Shea - Immunity 2007 cited by 1,474
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
Authors: Mandy J McGeachy, Yi Chen, Cristina M. Tato, Arian Laurence, Barbara Joyce-Shaikh, Wendy M. Blumenschein, Terrill K. McClanahan, John J. O’Shea, Daniel J Cua - Nature Immunology 2009 cited by 1,065
- Protein kinases: drug targets for immunological disorders
Authors: Leslie Castelo‐Soccio, Hanna Kim, Massimo Gadina, Pamela L. Schwartzberg, Arian Laurence, John J. O’Shea - Nature reviews. Immunology 2023 cited by 107
- Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis
Authors: Lydia Durant, Wendy T. Watford, Haydeé L. Ramos, Arian Laurence, Golnaz Vahedi, Lai Wei, Hayato Takahashi, Hong‐Wei Sun, Yuka Kanno, Fiona Powrie, John J. O’Shea - Immunity 2010 cited by 727
- Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
Authors: Daniel Chauss, Tilo Freiwald, Reuben McGregor, Bingyu Yan, Luopin Wang, Estefanía Nova‐Lamperti, Dhaneshwar Kumar, Zonghao Zhang, Heather Teague, Erin E. West, Kevin M. Vannella, Marcos J. Ramos-Benítez, Jack Bibby, Audrey Kelly, Amna Malik, Alexandra F. Freeman, Daniella M. Schwartz, Didier Portilla, Daniel S. Chertow, Susan John, Paul Lavender, Claudia Kemper, Giovanna Lombardi, Nehal N. Mehta, Nichola Cooper, Michail S. Lionakis, Arian Laurence, Majid Kazemian, Behdad Afzali - Nature Immunology 2021 cited by 205
- SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation
Authors: Bingyu Yan, Tilo Freiwald, Daniel Chauss, Luopin Wang, Erin E. West, Carmen Mirabelli, Charles J. Zhang, Eva-Maria Nichols, Nazish T. Malik, Richard Gregory, Marcus Bantscheff, Sonja Ghidelli‐Disse, Martin Kolev, Tristan Frum, Jason R. Spence, Jonathan Z. Sexton, Konstantinos D. Alysandratos, Darrell N. Kotton, Stefania Pittaluga, Jack Bibby, Nathalie Niyonzima, Matthew R. Olson, Shahram Kordasti, Didier Portilla, Christiane E. Wobus, Arian Laurence, Michail S. Lionakis, Claudia Kemper, Behdad Afzali, Majid Kazemian - Science Immunology 2021 cited by 203
- Janus kinase inhibitors in autoimmune diseases
Authors: John J. O’Shea, Apostolos Kontzias, Kunihiro Yamaoka, Yoshiya Tanaka, Arian Laurence - Annals of the Rheumatic Diseases 2013 cited by 455
- Effect of Huaier granule on recurrence after curative resection of HCC: a multicentre, randomised clinical trial
Authors: Qian Chen, Chang Shu, Arian Laurence, Yan Chen, Baogang Peng, Zuojun Zhen, Jianqiang Cai, Yitao Ding, Le-qun Li, Yubao Zhang, Qichang Zheng, Ge‐Liang Xu, Bo Li, Weiping Zhou, Shouwang Cai, Xiyan Wang, Hao Wen, Xinyu Peng, Xuewen Zhang, Chaoliu Dai, Ping Bie, Baocai Xing, Zhiren Fu, Lianxin Liu, Yi Mu, Ling Zhang, Qishun Zhang, Bin Jiang, Haixin Qian, Yijun Wang, Jingfeng Liu, Xihu Qin, Qiang Li, Ping Yin, Zhiwei Zhang, Xiaoping Chen - Gut 2018 cited by 258
- A central role for STAT5 in the transcriptional programing of T helper cell metabolism
Authors: Alejandro V. Villarino, Arian Laurence, Fred P. Davis, Luis Nivelo, Stephen R. Brooks, Hong‐Wei Sun, Kan Jiang, Behdad Afzali, Daniela Frasca, Lothar Hennighausen, Yuka Kanno, John J. O’Shea - Science Immunology 2022 cited by 53
- An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist
Authors: Ivona Aksentijevich, Seth L. Masters, Polly J. Ferguson, Paul Dancey, Joost Frenkel, Annet van Royen-Kerkhoff, R M Laxer, Ulf Tedgård, Edward W. Cowen, Tuyet‐Hang Pham, Matthew G. Booty, Jacob D. Estes, Netanya G. Sandler, Nicole Plass, Deborah L. Stone, Maria L. Turner, Suvimol Hill, John A. Butman, Rayfel Schneider, Paul Babyn, Hatem El‐Shanti, Elena Pope, Karyl S. Barron, Xinyu Bing, Arian Laurence, Chyi‐Chia Richard Lee, Dawn Chapelle, Gillian I. Clarke, Kamal Ohson, Marc Nicholson, Massimo Gadina, Barbara Yang, Benjamin D. Korman, Peter K. Gregersen, P. Martin van Hagen, A. Elisabeth Hak, Marjan Huizing, Proton Rahman, Daniel C. Douek, Elaine F. Remmers, Daniel L. Kastner, Raphaela Goldbach‐Mansky - New England Journal of Medicine 2009 cited by 992
- Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature
Authors: Pawel Muranski, Zachary A. Borman, Sid P. Kerkar, Christopher A. Klebanoff, Yun Ji, Luis Sánchez-Pérez, Madhusudhanan Sukumar, Robert Reger, Zhiya Yu, Steven J. Kern, Rahul Roychoudhuri, Gabriela A. Ferreyra, Wei Shen, Scott K. Durum, Lionel Feigenbaum, Douglas C. Palmer, Paul A. Antony, Chi‐Chao Chan, Arian Laurence, Robert L. Danner, Luca Gattinoni, Nicholas P. Restifo - Immunity 2011 cited by 440
- Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Authors: Joshua D. Milner, Jason M. Brenchley, Arian Laurence, Alexandra F. Freeman, Brenna J. Hill, Kevin M. Elias, Yuka Kanno, Christine Spalding, Houda Zghal Elloumi, Michelle L. Paulson, Joie Davis, Amy P. Hsu, Ava I. Asher, John J. O’Shea, Steven M. Holland, William E. Paul, Daniel C. Douek - Nature 2008 cited by 1,152
- The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion
Authors: Yu Xia, Na Liu, Xiuxiu Xie, Guoyu Bi, Hongping Ba, Lin Li, Jinxia Zhang, Xiaofei Deng, Yao Yao, Zhaohui Tang, Binjiao Yin, Jing Wang, Kan Jiang, Zhuoya Li, Yongwon Choi, Feili Gong, Xiang Cheng, John J. O’Shea, Jae Jin Chae, Arian Laurence, Xiang‐Ping Yang - Autophagy 2019 cited by 173
- Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
Authors: Xiang‐Ping Yang, Kamran Ghoreschi, Scott Steward-Tharp, Jaime Rodriguez‐Canales, Jinfang Zhu, John R. Grainger, Kiyoshi Hirahara, Hong‐Wei Sun, Lai Wei, Golnaz Vahedi, Yuka Kanno, John J. O’Shea, Arian Laurence - Nature Immunology 2011 cited by 576
- Targeting JAK/STAT signalling in inflammatory skin diseases with small molecule inhibitors
Authors: K. H. Welsch, Julia Holstein, Arian Laurence, Kamran Ghoreschi - European Journal of Immunology 2017 cited by 163
- Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system
Authors: Jason S. Stumhofer, Arian Laurence, Emma H. Wilson, Elaine Huang, Cristina M. Tato, Leanne M. Johnson, Alejandro V. Villarino, Qiulong Huang, Akihiko Yoshimura, David Sehy, Christiaan J. M. Saris, John J. O’Shea, Lothar Hennighausen, Matthias Ernst, Christopher A. Hunter - Nature Immunology 2006 cited by 942
- STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease
Authors: Arian Laurence, Shoba Amarnath, Jacopo Mariotti, Yong Chan Kim, Jason Foley, Michael Eckhaus, John J. O’Shea, Daniel H. Fowler - Immunity 2012 cited by 198
- IL-21 Is Produced by Th17 Cells and Drives IL-17 Production in a STAT3-dependent Manner
Authors: Lai Wei, Arian Laurence, Kevin M. Elias, John J. O’Shea - Journal of Biological Chemistry 2007 cited by 629
- Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
Authors: Kevin M. Elias, Arian Laurence, Todd S. Davidson, Geoffrey L. Stephens, Yuka Kanno, Ethan M. Shevach, John J. O’Shea - Blood 2007 cited by 444
