Charles Glabe
Active 1977–2024
- 116
- Papers
- 35,320
- Citations
- 93
- h-index
- 116
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine64.7%
- Biochemistry, Genetics and Molecular Biology19%
- Neuroscience8.7%
- Immunology and Microbiology1.5%
- Materials Science1.4%
- Chemistry1.1%
- Other3.6%
Topics
- Alzheimer's disease research and treatments21.8%
- Cholinesterase and Neurodegenerative Diseases4.9%
- Computational Drug Discovery Methods4.6%
- Neuroinflammation and Neurodegeneration Mechanisms4.1%
- Prion Diseases and Protein Misfolding3.1%
- Protein Structure and Dynamics2.9%
- Other58.6%
Coauthors
- Rakez Kayed26
- Saskia Milton13
- Carl W. Cotman8
- Elizabeth Head8
- Anna Pensalfini7
- Austin J. Yang7
- Suhail Rasool7
- David Eisenberg6
- Jessica Wu6
- M.R. Sawaya6
- Ricardo Albay6
- William Garzon-Rodriguez6
- Asa Hatami5
- Duilio Cascio5
- Leonid Breydo5
- Mihaela Necula5
- Peter C. Butler5
- Stephan Philipp5
- Tatyana Gurlo5
- Andrea J. Tenner4
- David H. Cribbs4
- Floyd Sarsoza4
- Harry V. Vinters4
- Jorge Mauricio Reyes‐Ruiz4
All papers
- Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo
Authors: Fusheng Yang, Giselle P. Lim, Aynun N. Begum, Oliver J. Ubeda, Mychica Simmons, Surendra S. Ambegaokar, Pingping P. Chen, Rakez Kayed, Charles Glabe, Sally A. Frautschy, Gregory M. Cole - Journal of Biological Chemistry 2004 cited by 2,306
- Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
Authors: Rakez Kayed, Elizabeth Head, Jennifer L. Thompson, Theresa M. McIntire, Saskia Milton, Carl W. Cotman, Charles Glabe - Science 2003 cited by 4,088
- Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease
Authors: Justyna Sosna, Stephan Philipp, Ricardo Albay, Jorge Mauricio Reyes‐Ruiz, David Baglietto‐Vargas, Frank M. LaFerla, Charles Glabe - Molecular Neurodegeneration 2018 cited by 410
- A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric Aβ, and Frank Neuronal Loss
Authors: Robert M. Cohen, Kavon Rezai‐Zadeh, Tara M. Weitz, Altan Rentsendorj, David Gate, Inna Spivak, Yasmin Bholat, Vitaly Vasilevko, Charles Glabe, Joshua J. Breunig, Pasko Rakić, Hayk Davtyan, Michael G. Agadjanyan, Vladimir Kepe, Jorge R. Barrio, Serguei Bannykh, Christine A. Szekely, Robert N. Pechnick, Terrence Town - Journal of Neuroscience 2013 cited by 546
- Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril
Authors: Marielle Aulikki Wälti, Francesco Ravotti, Hiromi Arai, Charles Glabe, Joseph S. Wall, Anja Böckmann, Peter Güntert, Beat H. Meier, Roland Riek - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 822
- Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
Authors: Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing, Carl W. Cotman, Mihaela Necula, Lawrence Margol, Jessica Wu, Leonid Breydo, Jennifer L. Thompson, Suhail Rasool, Tatyana Gurlo, Peter C. Butler, Charles Glabe - Molecular Neurodegeneration 2007 cited by 782
- RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory
Authors: Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, Rakez Kayed, Charles Glabe, Austin J. Yang, Michela Gallagher, Karen H. Ashe - Nature 2006 cited by 2,758
- Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-SynucleinopathyIn Vivo
Authors: Emanuela Colla, Poul Henning Jensen, Olga Pletniková, Juan C. Troncoso, Charles Glabe, Michael K. Lee - Journal of Neuroscience 2012 cited by 328
- Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease
Authors: Emilie L. Castranio, Philip Hasel, Jean‐Vianney Haure‐Mirande, Angie V. Ramirez Jimenez, B. Wade Hamilton, Rachel D. Kim, Charles Glabe, Minghui Wang, Bin Zhang, Sam Gandy, Shane A. Liddelow, Michelle E. Ehrlich - Alzheimer s & Dementia 2022 cited by 74
- Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils
Authors: Romany Abskharon, Hope Pan, M.R. Sawaya, Paul M. Seidler, E. Olivares, Yu Chen, Kevin A. Murray, Jeffrey Zhang, Carter Lantz, Megan Bentzel, David R. Boyer, Duilio Cascio, Binh A. Nguyen, Ke Hou, Xinyi Cheng, Els Pardon, Christopher Kazu Williams, Alissa L. Nana, Harry V. Vinters, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Jan Steyaert, Charles Glabe, Rachel R. Ogorzalek Loo, Joseph A. Loo, David Eisenberg - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 47
- Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology
Authors: Jean‐Vianney Haure‐Mirande, Mickaël Audrain, Tomas Fanutza, Soong Ho Kim, William L. Klein, Charles Glabe, Ben Readhead, Joel T. Dudley, Robert D. Blitzer, Minghui Wang, Bin Zhang, Eric E. Schadt, Sam Gandy, Michelle E. Ehrlich - Acta Neuropathologica 2017 cited by 128
- Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦
Authors: Angelo Demuro, Erene Mina, Rakez Kayed, Saskia Milton, Ian Parker, Charles Glabe - Journal of Biological Chemistry 2005 cited by 1,030
- Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
Authors: Justin Nussbaum, Stephan Schilling, Holger Cynis, Antônia Silva, Eric A. Swanson, Tanaporn Wangsanut, Kaycie K. Tayler, Brian J. Wiltgen, Asa Hatami, Raik Rönicke, Klaus G. Reymann, Birgit Hutter‐Paier, Anca Alexandru, Wolfgang Jagla, Sigrid Graubner, Charles Glabe, Hans‐Ulrich Demuth, George S. Bloom - Nature 2012 cited by 429
- Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
Authors: Kathryn Nichol, Wayne W. Poon, Anna Parachikova, David H. Cribbs, Charles Glabe, Carl W. Cotman - Journal of Neuroinflammation 2008 cited by 242
- Structure-based inhibitors of amyloid beta core suggest a common interface with tau
Authors: Sarah L. Griner, Paul M. Seidler, Jeannette T. Bowler, Kevin A. Murray, Tianxiao Yang, Shruti Sahay, M.R. Sawaya, Duilio Cascio, José A. Rodríguez, Stephan Philipp, Justyna Sosna, Charles Glabe, Tamir Gonen, David Eisenberg - eLife 2019 cited by 116
- Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases
Authors: Tina Bilousova, Carol A. Miller, Wayne W. Poon, Harry V. Vinters, María M. Corrada, Claudia H. Kawas, Eric Y. Hayden, David B. Teplow, Charles Glabe, Ricardo Albay, Gregory M. Cole, Edmond Teng, Karen H. Gylys - American Journal Of Pathology 2015 cited by 110
- Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease
Authors: Suman Rimal, Yu Li, Rasika Vartak, Ji Geng, Ishaq Tantray, Shuangxi Li, Sungun Huh, Hannes Vogel, Charles Glabe, Lea T. Grinberg, Salvatore Spina, William W. Seeley, Su Guo, Bingwei Lu - Acta Neuropathologica Communications 2021 cited by 64
- Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases
Authors: Rakez Kayed, Yuri Sokolov, Brian Edmonds, Theresa M. McIntire, Saskia Milton, James E. Hall, Charles Glabe - Journal of Biological Chemistry 2004 cited by 904
- Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia
Authors: Irina A. Buhimschi, Unzila Nayeri, Guomao Zhao, Lydia L. Shook, Anna Pensalfini, Edmund F. Funai, Ira M. Bernstein, Charles Glabe, Catalin S. Buhimschi - Science Translational Medicine 2014 cited by 482
- Progressive accumulation of amyloid‐β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins
Authors: Emiley Pham, Leslie Crews, Kiren Ubhi, Lawrence A. Hansen, Anthony Adame, Anna Cartier, David P. Salmon, Douglas Galasko, Sarah Michael, Jeffrey N. Savas, John R. Yates, Charles Glabe, Eliezer Masliah - FEBS Journal 2010 cited by 218
- Familial Alzheimer’s Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide
Authors: Asa Hatami, Sanaz Monjazeb, Saskia Milton, Charles Glabe - Journal of Biological Chemistry 2017 cited by 150
- Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques
Authors: Anna Pensalfini, Ricardo Albay, Suhail Rasool, Jessica Wu, Asa Hatami, Hiromi Arai, Lawrence Margol, Saskia Milton, Wayne W. Poon, María M. Corrada, Claudia H. Kawas, Charles Glabe - Neurobiology of Disease 2014 cited by 128
- Epitomic Characterization of the Specificity of the Anti-Amyloid Aβ Monoclonal Antibodies 6E10 and 4G8
Authors: Ibtisam Baghallab, Jorge Mauricio Reyes‐Ruiz, Khalid O. Abulnaja, Etimad Huwait, Charles Glabe - Journal of Alzheimer s Disease 2018 cited by 94
- Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity
Authors: Jacqueline F. Rivera, Safia Costes, Tatyana Gurlo, Charles Glabe, Peter C. Butler - Journal of Clinical Investigation 2014 cited by 205
