Michael K. Lee
Active 1988–2025
- 82
- Papers
- 24,063
- Citations
- 66
- h-index
- 78
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine62.1%
- Biochemistry, Genetics and Molecular Biology22.2%
- Neuroscience11.7%
- Immunology and Microbiology1.3%
- Nursing0.8%
- Chemistry0.4%
- Other1.5%
Topics
- Alzheimer's disease research and treatments12.4%
- Parkinson's Disease Mechanisms and Treatments9%
- Amyotrophic Lateral Sclerosis Research4.7%
- Neuroinflammation and Neurodegeneration Mechanisms3.1%
- Nuclear Receptors and Signaling2.7%
- Neuroscience and Neuropharmacology Research2.6%
- Other65.5%
Coauthors
- Donald L. Price16
- David Borchelt14
- Neal G. Copeland13
- Don W. Cleveland12
- Juan C. Troncoso12
- Sangram S. Sisodia12
- Nancy A. Jenkins11
- Ted M. Dawson10
- Olga Pletniková8
- Gopal Thinakaran6
- Hilda H. Slunt6
- Donald H. Dean5
- Lee J. Martin5
- Philip C. Wong5
- Valina L. Dawson5
- Wanda L.H. Stirling5
- Alfonso Araque4
- Andrew J. Saykin4
- Connie Nakano4
- Emanuela Colla4
- Emily H. Trittschuh4
- Grace Kim4
- Héctor Martell-Martínez4
- Jesse Mez4
All papers
- Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase
Authors: Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson, Guilian Xu, Victoria Gonzales, Nancy A. Jenkins, Neal G. Copeland, Michael K. Lee, Linda H. Younkin, Steven L. Wagner, Steven G. Younkin, David Borchelt - Human Molecular Genetics 2003 cited by 1,599
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
Authors: Venu M. Nemani, Wei Lü, Victoria Berge, Ken Nakamura, Bibiana Onoa, Michael K. Lee, Farrukh A. Chaudhry, Roger A. Nicoll, Robert H. Edwards - Neuron 2010 cited by 1,067
- Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
Authors: Michael K. Lee, Wanda L.H. Stirling, Yanqun Xu, Xueying Xu, Dike Qui, Allen S. Mandir, Ted M. Dawson, Neal G. Copeland, Nancy A. Jenkins, Don L. Price - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 cited by 840
- α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton
Authors: Dalila G. Ordonez, Michael K. Lee, Mel Β. Feany - Neuron 2017 cited by 235
- Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future
Authors: Yonas E. Geda, Lon S. Schneider, Laura N. Gitlin, David S. Miller, Gwenn S. Smith, J. Simon Bell, Jovier D. Evans, Michael K. Lee, Anton P. Porsteinsson, Krista L. Lanctôt, Paul B. Rosenberg, David L. Sultzer, Paul T. Francis, Henry Brodaty, Prasad P. Padala, Chiadikaobi Onyike, Luis Agüera Ortiz, Sonia Ancoli‐Israel, Donald L. Bliwise, Jennifer L. Martin, Michael V. Vitiello, Kristine Yaffe, Phyllis C. Zee, Nathan Herrmann, Robert A. Sweet, Clive Ballard, Ni A. Khin, Cara L. Alfaro, Patrick S. Murray, Susan K. Schultz, Constantine G. Lyketsos, Neuropsychiatric Syndromes Professional Interest Area of ISTAART - Alzheimer s & Dementia 2013 cited by 381
- Endoplasmic Reticulum Stress Is Important for the Manifestations of α-SynucleinopathyIn Vivo
Authors: Emanuela Colla, Philippe Coune, Ying Liu, Olga Pletniková, Juan C. Troncoso, Takeshi Iwatsubo, Bernard L. Schneider, Michael K. Lee - Journal of Neuroscience 2012 cited by 380
- Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo
Authors: David Borchelt, Gopal Thinakaran, Christopher B. Eckman, Michael K. Lee, Frances Davenport, Tamara Ratovitsky, Cristian-Mihail Prada, Grace Kim, Sophia Seekins, Debra Yager, Hilda H. Slunt, Rong Wang, Mary Seeger, Allan I. Levey, Sam Gandy, Neal G. Copeland, Nancy A. Jenkins, Donald L. Price, Steven G. Younkin, Sangram S. Sisodia - Neuron 1996 cited by 1,485
- Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-SynucleinopathyIn Vivo
Authors: Emanuela Colla, Poul Henning Jensen, Olga Pletniková, Juan C. Troncoso, Charles Glabe, Michael K. Lee - Journal of Neuroscience 2012 cited by 328
- Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases
Authors: Jeanne M.M. Tan, Esther Wong, Donald S. Kirkpatrick, Olga Pletniková, Han Seok Ko, Shiam-Peng Tay, Michelle W. L. Ho, Juan C. Troncoso, Steven P. Gygi, Michael K. Lee, Valina L. Dawson, Ted M. Dawson, Kah‐Leong Lim - Human Molecular Genetics 2007 cited by 445
- ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
Authors: Lucie Bruijn, Mark W. Bêcher, Michael K. Lee, Kenton L. Anderson, N.A. Jenkins, Neal G. Copeland, Sangram S. Sisodia, Jeffrey D. Rothstein, David Borchelt, Donald L. Price, Don W. Cleveland - Neuron 1997 cited by 1,330
- Aggregation promoting C-terminal truncation of α-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations
Authors: Wenxue Li, Neva West, Emanuela Colla, Olga Pletniková, Juan C. Troncoso, Laura Marsh, Ted M. Dawson, Pekka Jäkälä, Tobias Hartmann, Donald L. Price, Michael K. Lee - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 467
- Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer
Authors: Jenna H. Newman, Charles B. Chesson, Nora L. Herzog, Praveen K. Bommareddy, Salvatore Aspromonte, Russell Pepe, Ricardo Estupinian, Mones Aboelatta, Stuti Buddhadev, Saeed Tarabichi, Michael K. Lee, Shengguo Li, Daniel Medina, Eileena F. Giurini, Kajal Gupta, Gabriel Guevara-Aleman, Marco Rossi, Christina Nowicki, Abdulkareem Abed, Josef W. Goldufsky, Joseph R. Broucek, Raquel Redondo, David Rotter, Sachin R. Jhawar, Shang-Jui Wang, Frederick J. Kohlhapp, Howard L. Kaufman, Paul G. Thomas, Vineet Gupta, Timothy M. Kuzel, Jochen Reiser, Joyce Paras, Michael P. Kane, Eric A. Singer, Jyoti Malhotra, Lisa Denzin, Derek B. Sant’Angelo, Arnold B. Rabson, Leonard Y. Lee, Ahmed Lasfar, John Langenfeld, Jason M. Schenkel, Mary J. Fidler, Emily S. Ruiz, Amanda L. Marzo, Jai S. Rudra, Ann W. Silk, Andrew Zloza - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 191
- Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death
Authors: Lee J. Martin, Yan Pan, Ann C. Price, Wanda Sterling, Neal G. Copeland, Nancy A. Jenkins, Donald L. Price, Michael K. Lee - Journal of Neuroscience 2006 cited by 679
- Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson’s Disease
Authors: Philipp Portz, Michael K. Lee - Cells 2021 cited by 56
- The Microtubule-associated Protein Tau Is Extensively Modified with O-linked N-acetylglucosamine
Authors: C. Shane Arnold, GailV.W. Johnson, Robert N. Cole, Dennis L.-Y. Dong, Michael K. Lee, Gerald W. Hart - Journal of Biological Chemistry 1996 cited by 342
- Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
Authors: Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal Dehankar, Cory C. Funk, Jordan Wilkins, Анна Степанова, Tara O’Hagan, Alexander Galkin, Jarred J. Nesbitt, Xiujuan Zhu, Utkarsh Tripathi, Slobodan Macura, Tamar Tchkonia, Tamar Pirtskhalava, James L. Kirkland, Rachel A. Kudgus, Renee A. Schoon, Joel M. Reid, Yu Yamazaki, Takahisa Kanekiyo, Song Zhang, Emirhan Nemutlu, Petras P. Dzeja, Adam Jaspersen, Ye In Christopher Kwon, Michael K. Lee, Eugenia Trushina - Communications Biology 2021 cited by 69
- An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
Authors: Philip C. Wong, Carlos A. Pardo, David Borchelt, Michael K. Lee, Neal G. Copeland, Nancy A. Jenkins, Sangram S. Sisodia, Don W. Cleveland, Donald L. Price - Neuron 1995 cited by 1,437
- Amyloid Pathology Is Associated with Progressive Monoaminergic Neurodegeneration in a Transgenic Mouse Model of Alzheimer's Disease
Authors: Ying Liu, Mi‐Jeong Yoo, Alena Savonenko, Wanda L.H. Stirling, Donald L. Price, David Borchelt, Laura A. Mamounas, W. Ernest Lyons, Mary E. Blue, Michael K. Lee - Journal of Neuroscience 2008 cited by 209
- Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.
Authors: David Borchelt, Michael K. Lee, Hilda S. Slunt, Michael Guarnieri, Zhenshu Xu, Philip C. Wong, R. H. Brown, Donald L. Price, Sangram S. Sisodia, Don W. Cleveland - National Academy of Sciences, Proceedings of the National Academy of Sciences 1994 cited by 628
- Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
Authors: Balvindar Singh, Ana Covelo, Héctor Martell-Martínez, Carmen Nanclares, Mathew A. Sherman, Emmanuel Okematti, Joyce Meints, Peter J. Teravskis, Christopher Gallardo, Alena Savonenko, Michael A. Benneyworth, Sylvain Lesné, Dezhi Liao, Alfonso Araque, Michael K. Lee - Acta Neuropathologica 2019 cited by 88
- α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment
Authors: Md. Razaul Karim, Elly E. Liao, Jaekwang Kim, Joyce Meints, Héctor Martínez, Olga Pletniková, Juan C. Troncoso, Michael K. Lee - Molecular Neurodegeneration 2020 cited by 66
- Lessons from inducible pluripotent stem cell models on neuronal senescence in aging and neurodegeneration
Authors: Isabelle R. de Luzy, Michael K. Lee, William C. Mobley, Lorenz Studer - Nature Aging 2024 cited by 28
- Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins
Authors: David Borchelt, Tamara Ratovitski, Judy van Lare, Michael K. Lee, Vicki Gonzales, Nancy A. Jenkins, Neal G. Copeland, Donald L. Price, Sangram S. Sisodia - Neuron 1997 cited by 1,030
- Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform
Authors: Takeshi Ishihara, Ming Hong, Bin Zhang, Yasushi Nakagawa, Michael K. Lee, John Q. Trojanowski, Virginia M.‐Y. Lee - Neuron 1999 cited by 560
