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William C. Mobley

Active 1974–2025

122
Papers
21,045
Citations
83
h-index
119
i10-index

Citations

Citations per year for William C. Mobley1974: 2 citations1975: 6 citations1976: 6 citations1977: 15 citations1978: 8 citations1979: 14 citations1980: 13 citations1981: 15 citations1982: 13 citations1983: 8 citations1984: 8 citations1985: 16 citations1986: 47 citations1987: 54 citations1988: 46 citations1989: 77 citations1990: 78 citations1991: 78 citations1992: 71 citations1993: 74 citations1994: 99 citations1995: 62 citations1996: 52 citations1997: 66 citations1998: 62 citations1999: 86 citations2000: 132 citations2001: 145 citations2002: 149 citations2003: 155 citations2004: 183 citations2005: 181 citations2006: 204 citations2007: 212 citations2008: 202 citations2009: 218 citations2010: 167 citations2011: 227 citations2012: 207 citations2013: 181 citations2014: 183 citations2015: 133 citations2016: 154 citations2017: 167 citations2018: 103 citations2019: 430 citations2020: 462 citations2021: 560 citations2022: 395 citations2023: 293 citations2024: 460 citations2025: 241 citations2026: 5 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,637 citing papers, 35.2% of this breakdownChina: 538 citing papers, 7.2% of this breakdownUnited Kingdom: 500 citing papers, 6.7% of this breakdownItaly: 405 citing papers, 5.4% of this breakdownGermany: 359 citing papers, 4.8% of this breakdownCanada: 298 citing papers, 4% of this breakdownSpain: 253 citing papers, 3.4% of this breakdownFrance: 251 citing papers, 3.3% of this breakdownJapan: 216 citing papers, 2.9% of this breakdownAustralia: 186 citing papers, 2.5% of this breakdownSwitzerland: 137 citing papers, 1.8% of this breakdownSweden: 135 citing papers, 1.8% of this breakdown
0%35.2%Other 21%

Institutions

Fields

  • Medicine37.1%
  • Neuroscience28.8%
  • Biochemistry, Genetics and Molecular Biology26.3%
  • Agricultural and Biological Sciences1.6%
  • Engineering1.2%
  • Materials Science1%
  • Other4%

Topics

  • Nerve injury and regeneration6.9%
  • Alzheimer's disease research and treatments6.3%
  • Neurogenesis and neuroplasticity mechanisms4.1%
  • Down syndrome and intellectual disability research3.3%
  • Neuroscience and Neuropharmacology Research2.9%
  • Cellular transport and secretion2.7%
  • Other73.8%

Coauthors

All papers

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  1. Enabling Technologies for Personalized and Precision Medicine

    Authors: Dean Ho, Stephen R. Quake, Edward R.B. McCabe, Wee Joo Chng, Edward Kai‐Hua Chow, Xianting Ding, Bruce D. Gelb, Geoffrey S. Ginsburg, Jason Hassenstab, Chih‐Ming Ho, William C. Mobley, Garry P. Nolan, Steven T. Rosen, Patrick Tan, Yun Yen, Ali Zarrinpar - Trends in biotechnology 2020 cited by 484

  2. Reversing a model of Parkinson’s disease with in situ converted nigral neurons

    Authors: Hao Qian, Xinjiang Kang, Jing Hu, Dongyang Zhang, Zhengyu Liang, Fan Meng, Xuan Zhang, Yuanchao Xue, Roy Maimon, Steven F. Dowdy, Neal K. Devaraj, Zhuan Zhou, William C. Mobley, Don W. Cleveland, Xiang‐Dong Fu - Nature 2020 cited by 488

  3. Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species

    Authors: Xu‐Qiao Chen, William C. Mobley - Frontiers in Neuroscience 2019 cited by 290

  4. Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair

    Authors: Michael V. Sofroniew, Charles L. Howe, William C. Mobley - Annual Review of Neuroscience 2001 cited by 1,277

  5. Dementia in Down's syndrome

    Authors: Clive Ballard, William C. Mobley, John Hardy, Gareth Williams, Anne Corbett - The Lancet Neurology 2016 cited by 263

  6. BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons

    Authors: Guillermo Moya‐Alvarado, Reynaldo Tiburcio‐Félix, María Raquel Ibáñez, Alejandro A Aguirre-Soto, Miguel V. Guerra, Chengbiao Wu, William C. Mobley, Eran Perlson, Francisca C. Bronfman - eLife 2023 cited by 98

  7. Down syndrome and Alzheimer's disease: Common pathways, common goals

    Authors: Dean M. Hartley, Thomas Blumenthal, María C. Carrillo, Gilbert DiPaolo, Lucille Esralew, Katheleen Gardiner, Ann-Charlotte Granholm, Khalid Iqbal, Michael Krams, Cynthia A. Lemere, Ira T. Lott, William C. Mobley, Seth Ness, Ralph A. Nixon, Huntington Potter, Roger H. Reeves, Marwan N. Sabbagh, Wayne Silverman, Benjamin Tycko, Michelle Sie Whitten, Thomas Wısnıewskı - Alzheimer s & Dementia 2014 cited by 302

  8. Further understanding the connection between Alzheimer's disease and Down syndrome

    Authors: Heather M. Snyder, Lisa J. Bain, Adam M. Brickman, María C. Carrillo, Anna J. Esbensen, Joaquı́n M. Espinosa, Fabian‐Xosé Fernandez, Juan Fortea, Sigan L. Hartley, Elizabeth Head, James A. Hendrix, Priya S. Kishnani, Florence Lai, Patrick J. Lao, Cynthia A. Lemere, William C. Mobley, Elliott J. Mufson, Huntington Potter, Shahid Zaman, Ann‐Charlotte Granholm, H. Diana Rosas, André Strydom, Michelle Sie Whitten, Michael S. Rafii - Alzheimer s & Dementia 2020 cited by 103

  9. Opportunities, barriers, and recommendations in Down syndrome research

    Authors: James A. Hendrix, Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson, Lisa J. Bain, Nicole Baumer, Anita Bhattacharyya, Dusan Bogunovic, Kelly N. Botteron, George T. Capone, Priya Chandan, Isabelle Chase, Brian Chicoine, Cécile Cieuta‐Walti, Lara R. DeRuisseau, Sophie Durand, Anna J. Esbensen, Juan Fortea, Sandra Giménez, Ann‐Charlotte Granholm, Laura J. Mattie, Elizabeth Head, Hampus Hillerstrom, Lisa M. Jacola, Matthew P. Janicki, Joan Jasien, Angela R. Kamer, Raymond D. Kent, Bernard Khor, Jeanne B. Lawrence, Catherine Lemonnier, Amy Feldman Lewanda, William C. Mobley, Paul E. Moore, Linda Nelson, Nicolas M. Oreskovic, Ricardo S. Osorio, David Patterson, Sonja A. Rasmussen, Roger H. Reeves, Nancy Roizen, Stephanie L. Santoro, Stephanie L. Sherman, Nasreen Talib, Ignacio E. Tapia, Kyle M. Walsh, Steven F. Warren, A. Nicole White, G. William Wong, John S. Yi - Translational Science of Rare Diseases 2021 cited by 99

  10. Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses

    Authors: Xu‐Qiao Chen, William C. Mobley - Frontiers in Neuroscience 2019 cited by 178

  11. CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons

    Authors: Gong‐Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket Rajan Gupte, Ranen Aviner, Patrick Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette R. Geller, Cathy Hou, Cristina Danita, Lydia‐Marie Joubert, Michael F. Schmid, Serena Yeung, Judith Frydman, William C. Mobley, Chengbiao Wu, Leslie M. Thompson, Wah Chiu - Nature Communications 2023 cited by 64

  12. Widespread changes in dendritic and axonal morphology in Mecp2‐mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

    Authors: Pavel V. Belichenko, Elena E. Wright, Nadia P. Belichenko, Eliezer Masliah, Hong Hua Li, William C. Mobley, Uta Francke - The Journal of Comparative Neurology 2009 cited by 277

  13. Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome

    Authors: Michael S. Rafii, Olivier Sol, William C. Mobley, Saskia Delpretti, Brian G. Skotko, Anna Burke, Marwan N. Sabbagh, Shauna H. Yuan, Robert A. Rissman, Margaret B. Pulsifer, Casey L. Evans, A. Carol Evans, Gregory Beth, Nicolas Fournier, Julian Gray, Antonio Melo dos Santos, Valerie Hliva, Marija Vukicevic, Marie Kosco‐Vilbois, Johannes Streffer, Andrea Pfeifer, Howard Feldman - JAMA Neurology 2022 cited by 54

  14. Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

    Authors: Wei Xu, April M. Weissmiller, Joseph White, Fang Fang, Xinyi Wang, Yiwen Wu, Matthew L. Pearn, Xiaobei Zhao, Mariko Sawa, Shengdi Chen, Shermali Gunawardena, Jianqing Ding, William C. Mobley, Chengbiao Wu - Journal of Clinical Investigation 2016 cited by 184

  15. Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention

    Authors: Kevin D. Rynearson, Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Phuong Nguyen, Brenda Hug, Mariko Sawa, Ann Becker, Brian Spencer, Jazmin Florio, Michael Mante, Bahar Salehi, Carlos Arias, Douglas Galasko, Brian P. Head, Graham Johnson, Jiunn H. Lin, Steven K. Duddy, Robert A. Rissman, William C. Mobley, Gopal Thinakaran, Rudolph E. Tanzi, Steven L. Wagner - The Journal of Experimental Medicine 2021 cited by 72

  16. Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model

    Authors: Mariko Sawa, Cassia Overk, Ann Becker, Dominique Derse, Ricardo Albay, Kim Weldy, Ahmad Salehi, Thomas G. Beach, Eric Doran, Elizabeth Head, Yang Yu, William C. Mobley - Alzheimer s & Dementia 2021 cited by 60

  17. Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

    Authors: Maria Z. Kounnas, Anne M. Danks, Soan Cheng, Curtis M. Tyree, Elizabeth Ackerman, Xulun Zhang, Kwangwook Ahn, Phuong Nguyen, Dan Comer, Long Mao, Chengzhi Yu, David Pleynet, Paul J. DiGregorio, Gönül Veliçelebi, Kenneth A. Stauderman, William T. Comer, William C. Mobley, Yue‐Ming Li, Sangram S. Sisodia, Rudolph E. Tanzi, Steven L. Wagner - Neuron 2010 cited by 254

  18. Targeting increased levels of APP in Down syndrome: Posiphen‐mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model

    Authors: Xu‐Qiao Chen, Ahmad Salehi, Matthew L. Pearn, Cassia Overk, Phuong D. Nguyen, Alexander M. Kleschevnikov, Maria L. Maccecchini, William C. Mobley - Alzheimer s & Dementia 2020 cited by 54

  19. Disentangling self from pain: mindfulness meditation–induced pain relief is driven by thalamic–default mode network decoupling

    Authors: Gabriel Riegner, Grace Posey, Valeria Oliva, Youngkyoo Jung, William C. Mobley, Fadel Zeidan - Pain 2022 cited by 41

  20. Lessons from inducible pluripotent stem cell models on neuronal senescence in aging and neurodegeneration

    Authors: Isabelle R. de Luzy, Michael K. Lee, William C. Mobley, Lorenz Studer - Nature Aging 2024 cited by 28

  21. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome

    Authors: Xin Wang, Yingjun Zhao, Xiaofei Zhang, Hedieh Badie, Ying Zhou, Yangling Mu, Li Shen Loo, Lei Cai, Robert C. Thompson, Bo Yang, Yaomin Chen, Peter F. Johnson, Chengbiao Wu, Guojun Bu, William C. Mobley, Dongxian Zhang, Fred H. Gage, Barbara Ranscht, Yun‐wu Zhang, Stuart A. Lipton, Wanjin Hong, Huaxi Xu - Nature Medicine 2013 cited by 263

  22. The 50th anniversary of the discovery of trisomy 21: The past, present, and future of research and treatment of Down syndrome

    Authors: André Mégarbané, Aimé Ravel, Clotilde Mircher, Franck Sturtz, Yann Grattau, M O Rethoré, Jean‐Maurice Delabar, William C. Mobley - Genetics in Medicine 2009 cited by 261

  23. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

    Authors: Yingjun Zhao, I‐Chu Tseng, Charles J. Heyser, Edward Rockenstein, Michael Mante, Anthony Adame, Qiuyang Zheng, Timothy Y. Huang, Xin Wang, Pharhad Eli Arslan, Paramita Chakrabarty, Chengbiao Wu, Guojun Bu, William C. Mobley, Yun‐wu Zhang, Peter St George‐Hyslop, Eliezer Masliah, Paul Fraser, Huaxi Xu - Neuron 2015 cited by 101

  24. TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

    Authors: Xiaobei Zhao, Xu‐Qiao Chen, Eugene Kiwo Han, Yue Hu, Paul K. Paik, Zhiyong Ding, Julia Overman, Alice Lau, Sarah H. Shahmoradian, Wah Chiu, Leslie M. Thompson, Chengbiao Wu, William C. Mobley - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 99