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Guojun Bu

Active 1992–2025

239
Papers
43,000
Citations
119
h-index
235
i10-index

Citations

Citations per year for Guojun Bu1978: 2 citations1992: 4 citations1993: 5 citations1994: 29 citations1995: 29 citations1996: 32 citations1997: 39 citations1998: 86 citations1999: 89 citations2000: 149 citations2001: 125 citations2002: 128 citations2003: 102 citations2004: 136 citations2005: 134 citations2006: 142 citations2007: 115 citations2008: 175 citations2009: 197 citations2010: 255 citations2011: 273 citations2012: 293 citations2013: 282 citations2014: 428 citations2015: 375 citations2016: 478 citations2017: 638 citations2018: 638 citations2019: 1,638 citations2020: 1,997 citations2021: 2,038 citations2022: 1,972 citations2023: 1,787 citations2024: 2,737 citations2025: 1,842 citations2026: 41 citations2027: 1 citations1979–1991: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,722 citing papers, 29.5% of this breakdownChina: 2,522 citing papers, 13% of this breakdownUnited Kingdom: 1,357 citing papers, 7% of this breakdownGermany: 911 citing papers, 4.7% of this breakdownCanada: 638 citing papers, 3.3% of this breakdownItaly: 621 citing papers, 3.2% of this breakdownSweden: 527 citing papers, 2.7% of this breakdownFrance: 524 citing papers, 2.7% of this breakdownSpain: 520 citing papers, 2.7% of this breakdownAustralia: 512 citing papers, 2.6% of this breakdownJapan: 459 citing papers, 2.4% of this breakdownNetherlands: 444 citing papers, 2.3% of this breakdown
0%29.5%Other 23.9%

Institutions

Fields

  • Medicine49.9%
  • Biochemistry, Genetics and Molecular Biology22.4%
  • Neuroscience19.8%
  • Immunology and Microbiology3.4%
  • Materials Science0.7%
  • Engineering0.7%
  • Other3.1%

Topics

  • Alzheimer's disease research and treatments13.7%
  • Neuroinflammation and Neurodegeneration Mechanisms6.7%
  • Dementia and Cognitive Impairment Research3.7%
  • Cholinesterase and Neurodegenerative Diseases2%
  • Neurological Disease Mechanisms and Treatments1.9%
  • Neuroscience and Neuropharmacology Research1.9%
  • Other70.1%

Coauthors

All papers

Open in search
  1. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

    Authors: Chia‐Chen Liu, Takahisa Kanekiyo, Huaxi Xu, Guojun Bu - Nature Reviews Neurology 2013 cited by 3,481

  2. Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

    Authors: Yu Yamazaki, Na Zhao, Thomas R. Caulfield, Chia‐Chen Liu, Guojun Bu - Nature Reviews Neurology 2019 cited by 1,437

  3. ApoE in Alzheimer’s disease: pathophysiology and therapeutic strategies

    Authors: Ana‐Caroline Raulin, Sydney V. Doss, Zachary A. Trottier, Tadafumi C. Ikezu, Guojun Bu, Chia‐Chen Liu - Molecular Neurodegeneration 2022 cited by 691

  4. Performance of plasma phosphorylated tau 181 and 217 in the community

    Authors: Michelle M. Mielke, Jeffrey L. Dage, Ryan D. Frank, Alicia Algeciras‐Schimnich, David S. Knopman, Val J. Lowe, Guojun Bu, Prashanthi Vemuri, Jonathan Graff‐Radford, Clifford R. Jack, Ronald C. Petersen - Nature Medicine 2022 cited by 491

  5. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

    Authors: Yingjun Zhao, Xilin Wu, Xiaoguang Li, Lu-Lin Jiang, Xun Gui, Yan Liu, Yu Sun, Bing Zhu, Juan Piña-Crespo, Muxian Zhang, Ningyan Zhang, Xiaochun Chen, Guojun Bu, Zhiqiang An, Timothy Y. Huang, Huaxi Xu - Neuron 2018 cited by 808

  6. TDP-43 Pathology in Alzheimer’s Disease

    Authors: Axel Meneses, Shunsuke Koga, Justin O’Leary, Dennis W. Dickson, Guojun Bu, Na Zhao - Molecular Neurodegeneration 2021 cited by 374

  7. ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias

    Authors: Yuka A. Martens, Na Zhao, Chia‐Chen Liu, Takahisa Kanekiyo, Austin J. Yang, Alison Goate, David M. Holtzman, Guojun Bu - Neuron 2022 cited by 339

  8. A reference human induced pluripotent stem cell line for large-scale collaborative studies

    Authors: Caroline B. Pantazis, Andrian Yang, Erika Lara, Justin A. McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kumar Kanaujiya, Jizhong Zou, David P. Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, Constance Medura, Christopher Tompkins, Stephen H. Hughes, Marianita Santiana, Faraz Faghri, Mike A. Nalls, Dan Vitale, Shannon Ballard, Yue Qi, Daniel M. Ramos, Kailyn Anderson, Julia T. Stadler, Priyanka Narayan, Jason Papademetriou, Luke Reilly, Matthew P. Nelson, Sanya Aggarwal, Leah U. Rosen, Peter Kirwan, Venkat Pisupati, Steven L. Coon, Sonja W. Scholz, Theresa Priebe, Miriam Öttl, Jian Dong, Marieke Meijer, Lara J.M. Janssen, Vanessa S. Lourenco, Rik van der Kant, Dennis Crusius, Dominik Paquet, Ana‐Caroline Raulin, Guojun Bu, Aaron Held, Brian J. Wainger, Rebecca Gabriele, Jackie M. Casey, Selina Wray, Dad Abu-Bonsrah, Clare L. Parish, Melinda S. Beccari, Don W. Cleveland, Emmy Li, Indigo V.L. Rose, Martin Kampmann, Carles Calatayud, Patrik Verstreken, Laurin Heinrich, Max Y. Chen, Birgitt Schüle, Dan Dou, Erika L.F. Holzbaur, Maria Clara Zanellati, Richa Basundra, Mohanish Deshmukh, Sarah Cohen, Richa Khanna, Malavika Raman, Zachary S. Nevin, Madeline Matia, Jonas Van Lent, Vincent Timmerman, Bruce R. Conklin, Katherine Johnson Chase, Ke Zhang, Salome Funes, Daryl A. Bosco, Lena Erlebach, Marc Welzer, Deborah Kronenberg‐Versteeg, Guochang Lyu, Ernest Arenas, Elena Coccia, Lily Sarrafha, Tim Ahfeldt, John C. Marioni, William C. Skarnes, Mark Cookson, Michael E. Ward, Florian T. Merkle - Cell stem cell 2022 cited by 304

  9. APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

    Authors: Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary Dabney Davis, Chia‐Chen Liu, Wenyan Lü, Xue Wang, Kai Chen, Yesesri Cherukuri, Lin Jia, Yuka A. Martens, Lucy Job, Francis Shue, Thanh Thanh L. Nguyen, Steven G. Younkin, Neill R. Graff‐Radford, Zbigniew K. Wszołek, David A. Brafman, Yan W. Asmann, Nilüfer Ertekin‐Taner, Takahisa Kanekiyo, Guojun Bu - Nature Communications 2020 cited by 373

  10. Solving neurodegeneration: common mechanisms and strategies for new treatments

    Authors: Lauren K. Wareham, Shane A. Liddelow, Sally Temple, Larry I. Benowitz, Adriana Di Polo, Cheryl L. Wellington, Jeffrey L. Goldberg, Zhigang He, Xin Duan, Guojun Bu, Albert A. Davis, Karthik Shekhar, Anna La Torre, David C. Chan, Marta Soler, John G. Flanagan, Preeti Subramanian, Sharyn L. Rossi, Thomas M. Brunner, Diane E. Bovenkamp, David J. Calkins - Molecular Neurodegeneration 2022 cited by 307

  11. Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities

    Authors: Jeremy A. Syrjanen, Michelle R. Campbell, Alicia Algeciras‐Schimnich, Prashanthi Vemuri, Jonathan Graff‐Radford, Mary M. Machulda, Guojun Bu, David S. Knopman, Clifford R. Jack, Ronald C. Petersen, Michelle M. Mielke - Alzheimer s & Dementia 2021 cited by 252

  12. Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease

    Authors: Yasuteru Inoue, Francis Shue, Guojun Bu, Takahisa Kanekiyo - Molecular Neurodegeneration 2023 cited by 292

  13. Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

    Authors: Yuka Atagi, Chia‐Chen Liu, Meghan M. Painter, Xiao‐Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S. Kang, Huaxi Xu, Steven G. Younkin, Pritam Das, John Denis Fryer, Guojun Bu - Journal of Biological Chemistry 2015 cited by 628

  14. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer’s disease

    Authors: Chia‐Chen Liu, Na Wang, Yuanxin Chen, Yasuteru Inoue, Francis Shue, Yingxue Ren, Minghui Wang, Wenhui Qiao, Tadafumi C. Ikezu, Zonghua Li, Jing Zhao, Yuka A. Martens, Sydney V. Doss, Cassandra L. Rosenberg, Suren Jeevaratnam, Lin Jia, Ana‐Caroline Raulin, Fangfang Qi, Yiyang Zhu, Alla Alnobani, Joshua A. Knight, Yixing Chen, Cynthia Linares, Aishe Kurti, John Denis Fryer, Bin Zhang, Long‐Jun Wu, Betty Y.S. Kim, Guojun Bu - Nature Immunology 2023 cited by 143

  15. Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes

    Authors: Michelle M. Mielke, Ryan D. Frank, Jeffrey L. Dage, Andreas Jeromin, Nicholas J. Ashton, Kaj Blennow, Thomas K. Karikari, Eugeen Vanmechelen, Henrik Zetterberg, Alicia Algeciras‐Schimnich, David S. Knopman, Val J. Lowe, Guojun Bu, Prashanthi Vemuri, Jonathan Graff‐Radford, Clifford R. Jack, Ronald C. Petersen - JAMA Neurology 2021 cited by 257

  16. ApoE4 Accelerates Early Seeding of Amyloid Pathology

    Authors: Chia‐Chen Liu, Na Zhao, Yuan Fu, Na Wang, Cynthia Linares, Chih-Wei Tsai, Guojun Bu - Neuron 2017 cited by 478

  17. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model

    Authors: Li Zhong, Ying Xu, Rengong Zhuo, Tingting Wang, Kai Wang, Ruizhi Huang, Daxin Wang, Yue Gao, Yifei Zhu, Xuan Sheng, Kai Chen, Na Wang, Lin Zhu, Dan Can, Yuka Marten, Mitsuru Shinohara, Chia‐Chen Liu, Dan Du, Hao Sun, Lei Wen, Huaxi Xu, Guojun Bu, Xiao‐Fen Chen - Nature Communications 2019 cited by 412

  18. Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function

    Authors: Chia‐Chen Liu, Jing Zhao, Yuan Fu, Yasuteru Inoue, Yingxue Ren, Yuanxin Chen, Sydney V. Doss, Francis Shue, Suren Jeevaratnam, Ligia I. Bastea, Na Wang, Yuka A. Martens, Wenhui Qiao, Minghui Wang, Na Zhao, Lin Jia, Yu Yamazaki, Akari Yamazaki, Cassandra L. Rosenberg, Zhen Wang, Dehui Kong, Zonghua Li, Lindsey A. Kuchenbecker, Zachary A. Trottier, Lindsey M. Felton, Justin Rogers, Zachary Quicksall, Cynthia Linares, Joshua A. Knight, Yixing Chen, Aishe Kurti, Takahisa Kanekiyo, John Denis Fryer, Yan W. Asmann, Peter Störz, Xusheng Wang, Junmin Peng, Bin Zhang, Betty Y.S. Kim, Guojun Bu - Nature Neuroscience 2022 cited by 164

  19. TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

    Authors: Li Zhong, Xuan Sheng, Wanbing Wang, Yanzhong Li, Rengong Zhuo, Kai Wang, Lianshuai Zhang, Dandan Hu, Yujuan Hong, Linting Chen, Hengjun Rao, Tingting Li, Muyang Chen, Zhihao Lin, Yun‐wu Zhang, Xin Wang, Xiao‐Xin Yan, Xiaochun Chen, Xiaochun Chen, Guojun Bu, Xiao‐Fen Chen, Xiao‐Fen Chen - Immunity 2023 cited by 152

  20. ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

    Authors: Takahisa Kanekiyo, Huaxi Xu, Guojun Bu - Neuron 2014 cited by 629

  21. ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

    Authors: Philip B. Verghese, Joseph M. Castellano, Kanchan Garai, Yinong Wang, Hong Jiang, Aarti R. Shah, Guojun Bu, Carl Frieden, David M. Holtzman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 561

  22. TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

    Authors: Honghua Zheng, Lin Jia, Chia‐Chen Liu, Zhouyi Rong, Li Zhong, Longyu Yang, Xiao‐Fen Chen, John Denis Fryer, Xin Wang, Yun‐wu Zhang, Huaxi Xu, Guojun Bu - Journal of Neuroscience 2017 cited by 319

  23. Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies

    Authors: Mitsuru Shinohara, Masaya Tachibana, Takahisa Kanekiyo, Guojun Bu - Journal of Lipid Research 2017 cited by 295

  24. APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease

    Authors: Zonghua Li, Francis Shue, Na Zhao, Mitsuru Shinohara, Guojun Bu - Molecular Neurodegeneration 2020 cited by 309