Christopher M. Overall
Active 1987–2025
- 160
- Papers
- 30,115
- Citations
- 97
- h-index
- 158
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology45.8%
- Medicine31.5%
- Dentistry5.4%
- Chemistry4.7%
- Immunology and Microbiology4.7%
- Neuroscience1.9%
- Other6%
Topics
- Protease and Inhibitor Mechanisms9.3%
- Peptidase Inhibition and Analysis6.1%
- Cell Adhesion Molecules Research3.5%
- Blood Coagulation and Thrombosis Mechanisms2.3%
- Advanced Proteomics Techniques and Applications1.9%
- Oral microbiology and periodontitis research1.7%
- Other75.2%
Coauthors
- Georgina S. Butler29
- Ulrich auf dem Keller16
- Antoine Dufour12
- Reinhild Kappelhoff12
- Eric W. Deutsch11
- Gilbert S. Omenn11
- Jaro Sodek11
- Nestor Solis11
- Philipp F. Lange11
- Charlotte Morrison10
- Lydie Lane10
- Amanda E. Starr9
- Anna Prudova9
- Eric M. Tam9
- Pitter F. Huesgen9
- Ruedi Aebersold9
- Théo Klein9
- Caroline L. Bellac8
- Jayachandran N. Kizhakkedathu8
- Jennifer E. Van Eyk8
- Jennifer H. Cox8
- Oliver Schilling8
- Peter A. Bell8
- Robert L. Moritz8
All papers
- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
Authors: Yuanmei Lou, Paul C. McDonald, Arusha Oloumi, Stephen Chia, Christina Ostlund, Ardalan Ahmadi, Alastair H. Kyle, Ulrich auf dem Keller, Samuel Leung, David Huntsman, Blaise Clarke, Brent W. Sutherland, Dawn Waterhouse, Marcel B. Bally, Calvin D. Roskelley, Christopher M. Overall, Andrew I. Minchinton, Fabio Pacchiano, Fabrizio Carta, Andrea Scozzafava, Nadia Touisni, Jean‐Yves Winum, Claudiu T. Supuran, Shoukat Dedhar - Cancer Research 2011 cited by 756
- A high-stringency blueprint of the human proteome
Authors: Subash Adhikari, Edouard C. Nice, Eric W. Deutsch, Lydie Lane, Gilbert S. Omenn, Stephen R. Pennington, Young‐Ki Paik, Christopher M. Overall, Fernando J. Corrales, Ileana M. Cristea, Jennifer E. Van Eyk, Mathias Uhlén, Cecilia Lindskog, Daniel W. Chan, Amos Bairoch, J. Waddington, Joshua Justice, Joshua LaBaer, Henry Rodriguez, Fuchu He, Markus Kostrzewa, Peipei Ping, Rebekah L. Gundry, Peter Stewart, Sanjeeva Srivastava, Sudhir Srivastava, Fábio César Sousa Nogueira, Gilberto B. Domont, Yves Vandenbrouck, Maggie P. Y. Lam, Sara A. Wennersten, Juan Antonio Vizcaíno, Marc R. Wilkins, Jochen M. Schwenk, Emma Lundberg, Nuno Bandeira, György Marko‐Varga, Susan T. Weintraub, Charles Pineau, Ulrike Kusebauch, Robert L. Moritz, Seong Beom Ahn, Magnus Palmblad, M Snyder, Ruedi Aebersold, Mark S. Baker - Nature Communications 2020 cited by 217
- Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
Authors: Christopher M. Overall, Oded Kleifeld - Nature reviews. Cancer 2006 cited by 1,205
- Proteolytic Cleavage—Mechanisms, Function, and “Omic” Approaches for a Near-Ubiquitous Posttranslational Modification
Authors: Théo Klein, Ulrich Eckhard, Antoine Dufour, Nestor Solis, Christopher M. Overall - Chemical Reviews 2017 cited by 228
- Aging-associated modifications of collagen affect its degradation by matrix metalloproteinases
Authors: Preety Panwar, Georgina S. Butler, Andrew Jamroz, Pouya Azizi, Christopher M. Overall, Dieter Brömme - Matrix Biology 2017 cited by 201
- Can we predict protein from mRNA levels?
Authors: Nikolaus Fortelny, Christopher M. Overall, Paul Pavlidis, Gabriela V. Cohen Freue - Nature, Nat. 2017 cited by 240
- Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0
Authors: Eric W. Deutsch, Lydie Lane, Christopher M. Overall, Nuno Bandeira, Mark S. Baker, Charles Pineau, Robert L. Moritz, Fernando J. Corrales, Sandra Orchard, Jennifer E. Van Eyk, Young‐Ki Paik, Susan T. Weintraub, Yves Vandenbrouck, Gilbert S. Omenn - Journal of Proteome Research 2019 cited by 128
- The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays
Authors: Jochen M. Schwenk, Gilbert S. Omenn, Zhi Sun, David Campbell, Mark S. Baker, Christopher M. Overall, Ruedi Aebersold, Robert L. Moritz, Eric W. Deutsch - Journal of Proteome Research 2017 cited by 243
- Strategies for MMP inhibition in cancer: innovations for the post-trial era
Authors: Christopher M. Overall, Carlos López-Otı́n - Nature reviews. Cancer 2002 cited by 1,349
- Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products
Authors: Oded Kleifeld, Alain Doucet, Ulrich auf dem Keller, Anna Prudova, Oliver Schilling, Rajesh K. Kainthan, Amanda E. Starr, Leonard J. Foster, Jayachandran N. Kizhakkedathu, Christopher M. Overall - Nature Biotechnology 2010 cited by 562
- Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics
Authors: David Rodrı́guez, Charlotte Morrison, Christopher M. Overall - Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2009 cited by 562
- DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics
Authors: Vivian Tam, Peikai Chen, Anita Yee, Nestor Solis, Théo Klein, Mateusz Kudelko, Rakesh Sharma, Wilson Chan, Christopher M. Overall, Lisbet Haglund, Pak C. Sham, Kathryn S.E. Cheah, Danny Chan - eLife 2020 cited by 69
- The 2022 Report on the Human Proteome from the HUPO Human Proteome Project
Authors: Gilbert S. Omenn, Lydie Lane, Christopher M. Overall, Charles Pineau, Nicolle H. Packer, Ileana M. Cristea, Cecilia Lindskog, Susan T. Weintraub, Sandra Orchard, Michael H. A. Roehrl, Edouard C. Nice, Siqi Liu, Nuno Bandeira, Yu‐Ju Chen, Tiannan Guo, Ruedi Aebersold, Robert L. Moritz, Eric W. Deutsch - Journal of Proteome Research 2022 cited by 60
- Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
Authors: Katarina Wolf, Yi Wu, Yueying Liu, Jörg Geiger, Eric M. Tam, Christopher M. Overall, M. Sharon Stack, Peter Friedl - Nature Cell Biology 2007 cited by 995
- Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome
Authors: Isabel Pablos, Yoan Machado, Hugo César Ramos de Jesus, Yasir Mohamud, Reinhild Kappelhoff, Cecilia Lindskog, Marli Vlok, Peter A. Bell, Georgina S. Butler, Peter M. Grin, Quynh Cao, Jenny Nguyen, Nestor Solis, Srinivas Abbina, Wioletta Rut, John C. Vederas, László Székely, Attila Szakos, Marcin Drąg, Jayachandran N. Kizhakkedathu, Karen Mossman, Jeremy A. Hirota, Eric Jan, Honglin Luo, Arinjay Banerjee, Christopher M. Overall - Cell Reports 2021 cited by 108
- π-HuB: the proteomic navigator of the human body
Authors: Fuchu He, Ruedi Aebersold, Mark S. Baker, Xiu‐Wu Bian, Xiaochen Bo, Daniel W. Chan, Cheng Chang, Luonan Chen, Xiangmei Chen, Yu‐Ju Chen, Heping Cheng, Ben C. Collins, Fernando J. Corrales, Jüergen Cox, E Weinan, Jennifer E. Van Eyk, Jia Fan, Pouya Faridi, Daniel Figeys, George F. Gao, Wen Gao, Zu‐Hua Gao, Keisuke Goda, Wilson Wen Bin Goh, Dongfeng Gu, Changjiang Guo, Tiannan Guo, Yuezhong He, Albert J. R. Heck, Henning Hermjakob, Tony Hunter, N. Gopalakrishna Iyer, Ying Jiang, Connie R. Jiménez, Lokesh Joshi, Neil L. Kelleher, Ming Li, Yang Li, Qingsong Lin, Cui Hua Liu, Fan Liu, Guang‐Hui Liu, Yansheng Liu, Zhihua Liu, Teck Yew Low, Ben Lü, Matthias Mann, Anming Meng, Robert L. Moritz, Edouard C. Nice, Guang Ning, Gilbert S. Omenn, Christopher M. Overall, Giuseppe Palmisano, Yaojin Peng, Charles Pineau, Terence Chuen Wai Poon, Anthony W. Purcell, Jie Qiao, Roger R. Reddel, Phillip J. Robinson, Paola Roncada, Chris Sander, Jiahao Sha, Erwei Song, Sanjeeva Srivastava, Aihua Sun, Siu Kwan Sze, Chao Tang, Liujun Tang, Ruijun Tian, Juan Antonio Vizcaíno, Chanjuan Wang, Chen Wang, Xiaowen Wang, Xinxing Wang, Yan Wang, Tobias Weiß, Mathias Wilhelm, Robert Winkler, Bernd Wollscheid, Limsoon Wong, Linhai Xie, Wei Xie, Tao Xu, Tianhao Xu, Liying Yan, Jing Yang, Xiao Yang, John R. Yates, Tao Yun, Qiwei Zhai, Bing Zhang, Hui Zhang, Lihua Zhang, Lingqiang Zhang, Pingwen Zhang, Yukui Zhang, Yu Zi Zheng, Qing Zhong and 62 more - Nature 2024 cited by 44
- Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses
Authors: Ulrich Eckhard, Pitter F. Huesgen, Oliver Schilling, Caroline L. Bellac, Georgina S. Butler, Jennifer H. Cox, Antoine Dufour, Verena Goebeler, Reinhild Kappelhoff, Ulrich auf dem Keller, Théo Klein, Philipp F. Lange, Giada Marino, Charlotte Morrison, Anna Prudova, David Rodrı́guez, Amanda E. Starr, Yili Wang, Christopher M. Overall - Matrix Biology 2015 cited by 214
- Human and mouse proteases: a comparative genomic approach
Authors: Xosé S. Puente, Luis Sánchez‐Pulido, Christopher M. Overall, Carlos López-Otı́n - Nature Reviews Genetics 2003 cited by 933
- Proteolytic Post-translational Modification of Proteins: Proteomic Tools and Methodology
Authors: Lindsay D. Rogers, Christopher M. Overall - Molecular & Cellular Proteomics 2013 cited by 174
- The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human
Authors: Éva Korpos, Nadir Kadri, Reinhild Kappelhoff, Jeannine Wegner, Christopher M. Overall, Ekkehard Weber, Dan Holmberg, Susanna Cardell, Lydia Sorokin - Diabetes 2012 cited by 159
- C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease
Authors: Antoine Dufour, Caroline L. Bellac, Ulrich Eckhard, Nestor Solis, Théo Klein, Reinhild Kappelhoff, Nikolaus Fortelny, Parker G. Jobin, Jacob Rozmus, Jennifer C. Mark, Paul Pavlidis, Vincent Dive, Sean J. Barbour, Christopher M. Overall - Nature Communications 2018 cited by 86
- Subsite Mapping of the Human Pancreatic α-Amylase Active Site through Structural, Kinetic, and Mutagenesis Techniques,
Authors: Gary D. Brayer, Gary Sidhu, R. Maurus, Edwin H. Rydberg, Curtis Braun, Yili Wang, Nham T. Nguyen, Christopher M. Overall, Stephen G. Withers - Biochemistry 2000 cited by 261
- Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen
Authors: Ulrich Eckhard, Pitter F. Huesgen, Hans Brandstetter, Christopher M. Overall - Journal of Proteomics 2013 cited by 87
- Inflammation Dampened by Gelatinase A Cleavage of Monocyte Chemoattractant Protein-3
Authors: G. Angus McQuibban, Jiang-Hong Gong, Eric M. Tam, Christopher A. McCulloch, Ian Clark‐Lewis, Christopher M. Overall - Science 2000 cited by 776
