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Eric J.G. Sijbrands

Active 1999–2025

118
Papers
27,757
Citations
82
h-index
116
i10-index

Citations

Citations per year for Eric J.G. Sijbrands1974: 1 citations1988: 2 citations1991: 3 citations1997: 1 citations2000: 1 citations2001: 9 citations2002: 7 citations2003: 18 citations2004: 19 citations2005: 25 citations2006: 34 citations2007: 43 citations2008: 91 citations2009: 159 citations2010: 255 citations2011: 355 citations2012: 363 citations2013: 396 citations2014: 411 citations2015: 398 citations2016: 361 citations2017: 356 citations2018: 319 citations2019: 858 citations2020: 805 citations2021: 772 citations2022: 675 citations2023: 500 citations2024: 663 citations2025: 287 citations2026: 26 citations1975–1987: no citations, so these years are not shown1989–1990: no citations, so these years are not shown1992–1996: no citations, so these years are not shown1998–1999: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,947 citing papers, 19.1% of this breakdownUnited Kingdom: 1,317 citing papers, 8.5% of this breakdownChina: 941 citing papers, 6.1% of this breakdownNetherlands: 922 citing papers, 6% of this breakdownGermany: 768 citing papers, 5% of this breakdownItaly: 617 citing papers, 4% of this breakdownAustralia: 602 citing papers, 3.9% of this breakdownCanada: 590 citing papers, 3.8% of this breakdownSweden: 485 citing papers, 3.1% of this breakdownFrance: 435 citing papers, 2.8% of this breakdownSpain: 400 citing papers, 2.6% of this breakdownFinland: 365 citing papers, 2.3% of this breakdown
0%19.1%Other 32.8%

Institutions

Fields

  • Medicine57.6%
  • Biochemistry, Genetics and Molecular Biology29.9%
  • Neuroscience3.2%
  • Immunology and Microbiology2.3%
  • Nursing1.6%
  • Computer Science1%
  • Other4.4%

Topics

  • Genetic Associations and Epidemiology7.2%
  • Lipoproteins and Cardiovascular Health6.2%
  • Diabetes, Cardiovascular Risks, and Lipoproteins5.1%
  • Cholesterol and Lipid Metabolism2.2%
  • Lipid metabolism and disorders1.5%
  • Cancer, Lipids, and Metabolism1.5%
  • Other76.3%

Coauthors

All papers

Open in search
  1. Biological, clinical and population relevance of 95 loci for blood lipids

    Authors: Tanya M. Teslovich, Kiran Musunuru, Albert V. Smith, Andrew C. Edmondson, Ioannis M. Stylianou, Masahiro Koseki, James P. Pirruccello, Samuli Ripatti, Daniel I. Chasman, Cristen J. Willer, Christopher T. Johansen, Sigrid W. Fouchier, Aaron Isaacs, Gina M. Peloso, Maja Barbalić, Sally L. Ricketts, Joshua C. Bis, Yurii S. Aulchenko, Guðmar Þorleifsson, Mary F. Feitosa, John C. Chambers, Marju Orho‐Melander, Olle Melander, Toby Johnson, Xiaohui Li, Xiuqing Guo, Mingyao Li, Yoon Shin Cho, Min Jin Go, Young Jin Kim, Jong‐Young Lee, Taesung Park, Kyunga Kim, Xueling Sim, Rick Twee‐Hee Ong, Damien C. Croteau‐Chonka, Leslie A. Lange, Joshua D. Smith, Kijoung Song, Jing Hua Zhao, Xin Yuan, Jian’an Luan, Claudia Lamina, Andreas Ziegler, Weihua Zhang, Robert Y.L. Zee, Alan F. Wright, Jacqueline C.M. Witteman, James F. Wilson, Gonneke Willemsen, H.‐Erich Wichmann, John B. Whitfield, Dawn Waterworth, Nicholas J. Wareham, Gérard Waeber, Péter Vollenweider, Benjamin F. Voight, Véronique Vitart, André G. Uitterlinden, Manuela Uda, Jaakko Tuomilehto, John R. Thompson, Toshiko Tanaka, Ida Surakka, Heather M. Stringham, Tim D. Spector, Nicole Soranzo, Johannes H. Smit, Juha Sinisalo, Kaisa Silander, Eric J.G. Sijbrands, Angelo Scuteri, James Scott, David Schlessinger, Serena Sanna, Veikko Salomaa, Juha Saharinen, Chiara Sabatti, Aimo Ruokonen, Igor Rudan, Lynda M. Rose, Robert Roberts, Mark J. Rieder, Bruce M. Psaty, Peter P. Pramstaller, Irene Pichler, Markus Perola, Brenda W.J.H. Penninx, Nancy L. Pedersen, Cristian Pattaro, Alex Parker, Guillaume Paré, Ben A. Oostra, Christopher J. O’Donnell, Markku S. Nieminen, Deborah A. Nickerson, Grant W. Montgomery, Thomas Meitinger, Ruth McPherson, Mark I. McCarthy and 109 more - Nature 2010 cited by 3,704

  2. Sharing ICU Patient Data Responsibly Under the Society of Critical Care Medicine/European Society of Intensive Care Medicine Joint Data Science Collaboration: The Amsterdam University Medical Centers Database (AmsterdamUMCdb) Example*

    Authors: Patrick Thoral, Jan M. Peppink, Ronald H. Driessen, Eric J.G. Sijbrands, Erwin J. O. Kompanje, Lewis J. Kaplan, Heatherlee Bailey, Jozef Kesecioğlu, Maurizio Cecconi, Matthew M. Churpek, Gilles Clermont, Mihaela van der Schaar, Ari Ercole, Armand R. J. Girbes, Paul Elbers - Critical Care Medicine 2021 cited by 262

  3. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Authors: Dan E. Arking, Vasyl Pihur, Aravinda Chakravarti, Gina M. Hilton, Gina Hilton, Aravinda Chakravarti, Murielle Bochud, Patricia B. Munroe, Sue Shaw-Hawkins, Toby Johnson, Mark J. Caulfield, Sue Shaw‐Hawkins, Patricia B. Munroe, Kenneth Rice, Ramachandran S. Vasan, Ramachandran S. Vasan, Martin G. Larson, Daniel Levy, Martin G. Larson, Thomas J. Wang, Daniel Levy, Albert V. Smith, Thor Aspelund, Daniel I. Chasman, Paul M. Ridker, Paul M. Ridker, Maria Soler Artigas, Daniel I. Chasman, Albert V. Smith, Vilmundur Guðnason, Thor Aspelund, Albert V. Smith, Vilmundur Guðnason, Thor Aspelund, Albert Hofman, María Soler Artigas, Nick Shrine, Louise V. Wain, Martin D. Tobin, André G. Uitterlinden, Najaf Amin, Yurii S. Aulchenko, Cornelia M. van Duijn, M. Arfan Ikram, Eric J.G. Sijbrands, John C. Chambers, Cornelia M. van Duijn, Peter Würtz, Ayşe Demirkan, Albert Hofman, Aaron Isaacs, Gonçalo R. Abecasis, Germaine C. Verwoert, André G. Uitterlinden, Eric J.G. Sijbrands, Joshua C. Bis, Bruce M. Psaty, Lenore Launer, Germaine C. Verwoert, Tamara B. Harris, M. Arfan Ikram, Jian’an Luan, Germaine C. Verwoert, André G. Uitterlinden, Simon Heath, Daniel Levy, Péter Vollenweider, Peter Würtz, Elin Org, Gudrun Veldre, John C. Chambers, Paul Elliott, Weihua Zhang, Gonçalo R. Abecasis, Jennifer L. Bragg‐Gresham, Uwe Völker, Alexander Teumer, Joshua C. Bis, Nicole L. Glazer, Bruce M. Psaty, Tamara B. Harris, Melissa N. Garcia, Lenore J. Launer, Nicole Soranzo, Jing Zhao, Ruth J. F. Loos, Nicholas J. Wareham, Mark Lathrop, Diana Zélénika, Simon Heath, Siim Sõber, Maris Laan, Gudrun Veldre, Elin Org, Halit Ongen, Anuj Goel, Afshin Parsa, Nanette Steinle, Alan R. Shuldiner, Yuri Milaneschi and 246 more - Nature 2011 cited by 2,083

  4. Clinical Genetic Testing for Familial Hypercholesterolemia

    Authors: Amy C. Sturm, Joshua W. Knowles, Samuel S. Gidding, Zahid Ahmad, Catherine D. Ahmed, Christie M. Ballantyne, Seth J. Baum, Mafalda Bourbon, Alain Carrié, Marina Cuchel, Sarah D. de Ferranti, Joep C. Defesche, Tomáš Freiberger, Ray E. Hershberger, G. Kees Hovingh, Lala Karayan, Johannes J.P. Kastelein, Iris Kindt, Stacey R. Lane, S. E. A. Leigh, MacRae F. Linton, Pedro Mata, William A. Neal, Børge G. Nordestgaard, Raúl D. Santos, Mariko Harada‐Shiba, Eric J.G. Sijbrands, Nathan O. Stitziel, Shizuya Yamashita, Katherine Wilemon, David H. Ledbetter, Daniel J. Rader - Journal of the American College of Cardiology 2018 cited by 597

  5. A guide to sharing open healthcare data under the General Data Protection Regulation

    Authors: Jip W T M de Kok, Miguel Ángel Armengol de la Hoz, Y. de Jong, Véronique Brokke, Paul Elbers, Patrick Thoral, Alejandro Castillejo, Tomás Trenor, José María Castellano, Alberto E. Bronchalo, Tobias M. Merz, Martin Faltys, Collaborator group, Cristina Casares, Araceli Jiménez, Jaime Requejo, Sonia Gutiérrez, David Curto, Gunnar Rätsch, Jan M. Peppink, Ronald H. Driessen, Eric J.G. Sijbrands, Erwin J. O. Kompanje, Armand R. J. Girbes, José Barberán, José F. Varona, Paula Villares, Iwan C.C. van der Horst, Minnan Xu, Leo Anthony Celi, Bas C. T. van Bussel, X. Borrat - Scientific Data 2023 cited by 91

  6. The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification

    Authors: Joana Rita Chora, Michael A. Iacocca, Lukáš Tichý, Hannah Wand, C. Lisa Kurtz, Heather Zimmermann, Annette Leon, Maggie Williams, Steve E. Humphries, Amanda J. Hooper, Mark Trinder, Liam R. Brunham, Alexandre C. Pereira, Cinthia Elim Jannes, Margaret Chen, Jessica Chonis, Jian Wang, Serra Kim, Tami Johnston, Přemysl Souček, Michal Kramárek, S. E. A. Leigh, Alain Carrié, Eric J.G. Sijbrands, Robert A. Hegele, Tomáš Freiberger, Joshua W. Knowles, Mafalda Bourbon - Genetics in Medicine 2021 cited by 164

  7. High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes

    Authors: Abbas Dehghan, Mandy van Hoek, Eric J.G. Sijbrands, Albert Hofman, Jacqueline C.M. Witteman - Diabetes Care 2008 cited by 656

  8. Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring

    Authors: Mohan Ghorasaini, Yassene Mohammed, Jerzy Adamski, Lisa Bettcher, John A. Bowden, Matías Cabruja, Kévin Contrepois, Mathew Ellenberger, Bharat Gajera, Mark Haid, Daniel Hornburg, Christie L. Hunter, Christina M. Jones, Théo Klein, Oleg A. Mayboroda, Mina Mirzaian, Ruin Moaddel, Luigi Ferrucci, Jacqueline Lovett, Kenneth Nazir, Mackenzie Pearson, Baljit K. Ubhi, Daniel Raftery, Fabien Riols, Rebekah Sayers, Eric J.G. Sijbrands, M Snyder, Baolong Su, Vidya Velagapudi, Kevin J. Williams, Yolanda B. de Rijke, Martin Giera - Analytical Chemistry 2021 cited by 99

  9. Efficacy of statins in familial hypercholesterolaemia: a long term cohort study

    Authors: Jorie Versmissen, Daniëlla M. Oosterveer, Mojgan Yazdanpanah, Joep C. Defesche, Dick C.G. Basart, Anho Liem, Jan Heeringa, J. C. M. Witteman, Peter Lansberg, J.J.P. Kastelein, Eric J.G. Sijbrands - BMJ 2008 cited by 719

  10. Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification

    Authors: Yannick Kaiser, Janine E. van der Toorn, Sunny S Singh, Kang H. Zheng, Maryam Kavousi, Eric J.G. Sijbrands, Erik S.G. Stroes, Meike W. Vernooij, Yolanda B. de Rijke, S. Matthijs Boekholdt, Daniël Bos - European Heart Journal 2022 cited by 92

  11. Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society Severe Familial Hypercholesterolemia Panel

    Authors: Raúl D. Santos, Samuel S. Gidding, Robert A. Hegele, Marina Cuchel, Philip J. Barter, Gerald F. Watts, Seth J. Baum, Alberico L. Catapano, M. John Chapman, Joep C. Defesche, Emanuela Folco, Tomáš Freiberger, Jacques Genest, G. Kees Hovingh, Mariko Harada‐Shiba, Steve E. Humphries, Ann S Jackson, Pedro Mata, Patrick M. Moriarty, Frederick J. Raal, Khalid Al‐Rasadi, Kausik K. Ray, Zelijko Reiner, Eric J.G. Sijbrands, Shizuya Yamashita - The Lancet Diabetes & Endocrinology 2016 cited by 418

  12. Genome-wide association study of blood pressure and hypertension

    Authors: Daniel Levy, Georg Ehret, Kenneth Rice, Germaine C. Verwoert, Lenore J. Launer, Abbas Dehghan, Nicole L. Glazer, Alanna C. Morrison, Andrew D. Johnson, Thor Aspelund, Yurii S. Aulchenko, Thomas Lumley, Anna Köttgen, Ramachandran S. Vasan, Fernando Rivadeneira, Guðný Eiríksdóttir, Xiuqing Guo, Dan E. Arking, Gary F. Mitchell, Francesco Mattace‐Raso, Albert V. Smith, Kent D. Taylor, Robert B. Scharpf, Shih-Jen Hwang, Eric J.G. Sijbrands, Joshua C. Bis, Tamara B. Harris, Santhi K. Ganesh, Christopher J. O’Donnell, Albert Hofman, Jerome I. Rotter, Josef Coresh, Emelia J. Benjamin, André G. Uitterlinden, Gerardo Heiss, Caroline S. Fox, Jacqueline C.M. Witteman, Eric Boerwinkle, Thomas J. Wang, Vilmundur Guðnason, Martin G. Larson, Aravinda Chakravarti, Bruce M. Psaty, Cornelia M. van Duijn - Nature Genetics 2009 cited by 1,383

  13. Genomic prediction of coronary heart disease

    Authors: Gad Abraham, Aki S. Havulinna, Oneil G. Bhalala, Sean Byars, Alysha De Livera, Laxman Yetukuri, Emmi Tikkanen, Markus Perola, Heribert Schunkert, Eric J.G. Sijbrands, Aarno Palotie, Nilesh J. Samani, Veikko Salomaa, Samuli Ripatti, Michael Inouye - European Heart Journal 2016 cited by 349

  14. Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia

    Authors: Representatives of the Global Familial Hypercholesterolemia Community, Katherine Wilemon, Jasmine Patel, Carlos A. Aguilar‐Salinas, Catherine D. Ahmed, Mutaz Al-Khnifsawi, Wael Almahmeed, Rodrigo Alonso, Khalid Al‐Rasadi, Lina Badimón, Luz Mery Bernal, Martin P. Bogsrud, Lynne T. Braun, Liam R. Brunham, Alberico L. Catapano, Kristýna Cillíková, Pablo Corral, Regina Cuevas, Joep C. Defesche, Olivier Descamps, Sarah D. de Ferranti, Jean-Luc Eiselé, Gerardo Elikir, Emanuela Folco, Tomáš Freiberger, Francesco Fuggetta, Isabel Gaspar, Ákos G. Gesztes, Urh Grošelj, Ian Hamilton‐Craig, Gabriele Hanauer-Mader, Mariko Harada‐Shiba, G. E. Hastings, G. Kees Hovingh, Maria Cristina de Oliveira Izar, Allison Jamison, Gunnar N. Karlsson, Meral Kayıkçıoğlu, Sue Koob, Masahiro Koseki, Stacey Lane, Marcos M. Lima-Martínez, Greizy López, Tânia Leme da Rocha Martinez, David Marais, Letrillart Marion, Pedro Mata, Inese Maurina, Diana Maxwell, Roopa Mehta, George A. Mensah, André R. Miserez, Dermot Neely, Stephen J. Nicholls, Atsushi Nohara, Børge G. Nordestgaard, Leiv Ose, Athanasios Pallidis, Jing Pang, Jules Payne, Amy L. Peterson, Monica P. Popescu, Raman Puri, Kausik K. Ray, Ashraf Reda, Tiziana Sampietro, Raúl D. Santos, Inge Schalkers, Laura Schreier, Michael D. Shapiro, Eric J.G. Sijbrands, Daniel Soffer, Claudia Stefanutti, Mario Stoll, Rody G. Sy, Marta Lucía Tamayo, Myra Tilney, Lâle Tokgözoğlu, Brian Tomlinson, Antonio J. Vallejo‐Vaz, Alejandra Vázquez-Cárdenas, Patrícia Vieira de Luca, David S Wald, Gerald F. Watts, Nanette K. Wenger, M. Allison Wolf, David Wood, Aram Zegerius, Thomas A. Gaziano, Samuel S. Gidding - JAMA Cardiology 2020 cited by 258

  15. The aging kidney revisited: A systematic review

    Authors: Davide Bolignano, Francesco Mattace‐Raso, Eric J.G. Sijbrands, Carmine Zoccali - Ageing Research Reviews 2014 cited by 258

  16. Associations of relative fat mass, a new index of adiposity, with type-2 diabetes in the general population

    Authors: Navin Suthahar, Kan Wang, Victor W Zwartkruis, Stephan J. L. Bakker, Silvio E. Inzucchi, Laura M.G. Meems, Tim R. Eijgenraam, Fariba Ahmadizar, Eric J.G. Sijbrands, Ron T. Gansevoort, Lyanne M. Kieneker, Dirk J. van Veldhuisen, Maryam Kavousi, Rudolf A. de Boer - European Journal of Internal Medicine 2023 cited by 61

  17. Review of first 5 years of screening for familial hypercholesterolaemia in the Netherlands

    Authors: Marina AW Umans-Eckenhausen, Joep C. Defesche, Eric J.G. Sijbrands, Robert LJM Scheerder, J. Kastelein - The Lancet 2001 cited by 493

  18. Insulin metabolism and the risk of Alzheimer disease

    Authors: Elisabeth M. C. Schrijvers, Jacqueline C.M. Witteman, Eric J.G. Sijbrands, Albert Hofman, P. J. Koudstaal, Monique M.B. Breteler - Neurology 2010 cited by 332

  19. Afamelanotide for Erythropoietic Protoporphyria

    Authors: Janneke G. Langendonk, Manisha Balwani, Karl E. Anderson, Herbert L. Bonkovsky, A. Anstey, D. Montgomery Bissell, Joseph R. Bloomer, Chris Edwards, Norbert Neumann, Charles Parker, John D. Phillips, Henry W. Lim, Iltefat Hamzavi, Jean‐Charles Deybach, Raili Kauppinen, Lesley E. Rhodes, Jorge Frank, Gillian Murphy, Francois Karstens, Eric J.G. Sijbrands, Felix W.M. de Rooij, Mark Lebwohl, Hetanshi Naik, Colin R. Goding, J.H.P. Wilson, Robert J. Desnick - New England Journal of Medicine 2015 cited by 279

  20. Lifetime risk of developing impaired glucose metabolism and eventual progression from prediabetes to type 2 diabetes: a prospective cohort study

    Authors: Symen Ligthart, Thijs T. W. van Herpt, Maarten J.G. Leening, Maryam Kavousi, Albert Hofman, Bruno H. Stricker, Mandy van Hoek, Eric J.G. Sijbrands, Oscar H. Franco, Abbas Dehghan - The Lancet Diabetes & Endocrinology 2015 cited by 268

  21. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Authors: Richa Saxena, the MAGIC investigators, Marie‐France Hivert, Claudia Langenberg, Toshiko Tanaka, James S. Pankow, Péter Vollenweider, Valeriya Lyssenko, Nabila Bouatia‐Naji, Josée Dupuis, Anne Jackson, W.H. Linda Kao, Man Li, Nicole L. Glazer, Alisa K Manning, Jian’an Luan, Heather M. Stringham, Inga Prokopenko, Toby Johnson, Niels Grarup, Trine Welløv Boesgaard, Cécile Lecoeur, Peter Shrader, Jeffrey R. O’Connell, Erik Ingelsson, David Couper, Kenneth Rice, Kijoung Song, Camilla Andreasen, Christian Dina, Anna Köttgen, Olivier Le Bacquer, François Pattou, Jalal Taneera, Valgerður Steinthórsdóttir, Denis Rybin, Kristin Ardlie, Michael Sampson, Lu Qi, Mandy van Hoek, Michael N. Weedon, Yurii S. Aulchenko, Benjamin F. Voight, Harald Grallert, Beverley Balkau, Richard N. Bergman, Suzette J. Bielinski, Amélie Bonnefond, Lori L. Bonnycastle, Knut Borch‐Johnsen, Yvonne Böttcher, Eric J. Brunner, Thomas A. Buchanan, Suzannah J. Bumpstead, Christine Cavalcanti-Proença, G. Charpentier, Yii-Der Ida Chen, Peter S. Chines, Francis S. Collins, Marilyn C. Cornelis, Gabriel Crawford, Jérôme Delplanque, Alex S. F. Doney, Josephine M. Egan, Michael R. Erdos, Mathieu Firmann, Nita G. Forouhi, Caroline S. Fox, Mark O. Goodarzi, Jürgen Graessler, Aroon D. Hingorani, Bo Isomaa, Torben Jørgensen, Mika Kivimäki, Péter Kovács, Knut Krohn, Meena Kumari, Torsten Lauritzen, Claire Lévy‐Marchal, Vladimir Mayor, Jarred B. McAteer, Stephen Eyre, Braxton D. Mitchell, Karen L. Mohlke, Mario A. Morken, Narisu Narisu, Colin N A Palmer, Ruth Pakyz, Laura Pascoe, Felicity Payne, Daniel S. Pearson, Wolfgang Rathmann, Annelli Sandbæk, Avan Aihie Sayer, Laura J. Scott, Stephen J. Sharp, Eric J.G. Sijbrands, Andrew B. Singleton, David S. Siscovick, Nicholas L. Smith and 13 more - Nature Genetics 2010 cited by 636

  22. Anxiety and depression in diabetes care: longitudinal associations with health-related quality of life

    Authors: Xiaona Liu, Juanita A. Haagsma, Eric J.G. Sijbrands, Hanneke Buijks, Laura Boogaard, Johan P. Mackenbach, Vicki Erasmus, Suzanne Polinder - Scientific Reports 2020 cited by 75

  23. Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype–phenotype relationship, and clinical outcome

    Authors: Barbara Sjouke, D. Meeike Kusters, Iris Kindt, Joost Besseling, Joep C. Defesche, Eric J.G. Sijbrands, Jeanine E. Roeters van Lennep, Anton F. H. Stalenhoef, Albert Wiegman, Jacqueline de Graaf, Sigrid W. Fouchier, John J.P. Kastelein, G. Kees Hovingh - European Heart Journal 2014 cited by 442

  24. Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

    Authors: John J.P. Kastelein, Fatima Akdim, Erik S.G. Stroes, Aeilko H. Zwinderman, Michiel L. Bots, Anton F. H. Stalenhoef, Frank L.J. Visseren, Eric J.G. Sijbrands, Mieke D. Trip, Evan A. Stein, Daniel Gaudet, Raphaël Duivenvoorden, Enrico P. Veltri, Adéle Marais, Eric de Groot - New England Journal of Medicine 2008 cited by 1,243