Federico Mingozzi
Active 2001–2025
- 109
- Papers
- 25,079
- Citations
- 74
- h-index
- 106
- i10-index
Citations
Citation sources
Countries
Institutions
- University of Pennsylvania1.6%
- Inserm1.5%
- University of Florida1.3%
- University College London1.2%
- Harvard University1.1%
- Children's Hospital of Philadelphia0.9%
- Other92.4%
Fields
- Biochemistry, Genetics and Molecular Biology68.8%
- Medicine22.7%
- Neuroscience4.6%
- Immunology and Microbiology2.2%
- Engineering0.7%
- Materials Science0.4%
- Other0.6%
Topics
- Virus-based gene therapy research15.8%
- CRISPR and Genetic Engineering8.8%
- RNA Interference and Gene Delivery7.1%
- Retinal Development and Disorders5.3%
- CAR-T cell therapy research4.2%
- Viral Infectious Diseases and Gene Expression in Insects3.4%
- Other55.4%
Coauthors
- Katherine A. High39
- Giuseppe Ronzitti29
- Fanny Collaud24
- J. Fraser Wright14
- Christian Leborgne11
- Daniel J. Hui11
- Shangzhen Zhou11
- Séverine Charles11
- Klaudia Kuranda10
- Laetitia van Wittenberghe10
- Valder R. Arruda10
- Etiena Basner‐Tschakarjan9
- Marcelo Simon Sola9
- P. Véron9
- Pasqualina Colella9
- Helena Costa Verdera8
- Albert M. Maguire7
- Hildegund C.J. Ertl7
- Jeannette Bennicelli7
- Pauline Sellier7
- Roland W. Herzog7
- Amine Meliani6
- Andrés F. Muro6
- Elena Barbon6
All papers
- Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
Authors: Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda, Bertil Glader, Margaret V. Ragni, John E.J. Rasko, Margareth C. Ozelo, Keith Hoots, Philip M. Blatt, Barbara A. Konkle, Michael D. Dake, Robin Kaye, Mahmood Razavi, Albert Zajko, James L. Zehnder, Pradip K. Rustagi, Hiroyuki Nakai, Amy Chew, Debra G. B. Leonard, J Fraser Wright, Ruth Lessard, Jürg M. Sommer, Michael Tigges, Denise E. Sabatino, Alvin Luk, Haiyan Jiang, Federico Mingozzi, Linda Couto, Hildegund C.J. Ertl, Katherine A. High, Mark A. Kay - Nature Medicine 2006 cited by 2,135
- AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer
Authors: Helena Costa Verdera, Klaudia Kuranda, Federico Mingozzi - Molecular Therapy 2020 cited by 627
- Emerging Issues in AAV-Mediated In Vivo Gene Therapy
Authors: Pasqualina Colella, Giuseppe Ronzitti, Federico Mingozzi - Molecular Therapy — Methods & Clinical Development 2017 cited by 864
- Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
Authors: Amit C. Nathwani, Edward G. D. Tuddenham, Savita Rangarajan, Cecilia Rosales, Jenny McIntosh, David C. Linch, Pratima Chowdary, Anne Riddell, Arnulfo Pie, Chris F. Harrington, James O’Beirne, Keith Smith, John Pasi, Bertil Glader, Pradip K. Rustagi, Catherine Y. Ng, Mark A. Kay, Junfang Zhou, Yunyu Spence, Christopher L. Morton, James A. Allay, John B. Coleman, Susan Sleep, John M. Cunningham, Deo Kumar Srivastava, Etiena Basner‐Tschakarjan, Federico Mingozzi, Katherine A. High, John T. Gray, Ulrike M. Reiss, Arthur W. Nienhuis, Andrew M. Davidoff - New England Journal of Medicine 2011 cited by 1,843
- Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B
Authors: Amit Nathwani, Ulreke M. Reiss, Edward G. D. Tuddenham, Cecilia Rosales, Pratima Chowdary, Jenny McIntosh, Marco Della Peruta, Elsa Lhériteau, Nishal Patel, Deepak B. Thimiri Govinda Raj, Anne Riddell, Jun Pie, Savita Rangarajan, David Bevan, Michael Recht, Yu‐Min Shen, Kathleen G. Halka, Etiena Basner‐Tschakarjan, Federico Mingozzi, Katherine A. High, James A. Allay, Mark A. Kay, Catherine Y. Ng, Junfang Zhou, Maria Cancio, Christopher L. Morton, John T. Gray, Deo Kumar Srivastava, Arthur W. Nienhuis, Andrew M. Davidoff - New England Journal of Medicine 2014 cited by 1,250
- Immune responses to AAV vectors: overcoming barriers to successful gene therapy
Authors: Federico Mingozzi, Katherine A. High - Blood 2013 cited by 920
- IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies
Authors: Christian Leborgne, Elena Barbon, J M Alexander, Hayley A. Hanby, Sandrine Delignat, Daniel M. Cohen, Fanny Collaud, Saghana Muraleetharan, Dan Lupo, Joseph Silverberg, Karen Huang, Laetitia van Wittengerghe, Béatrice Marolleau, Adeline Miranda, Anna Fabiano, Victoria Daventure, Heena Beck, Xavier M. Anguela, Giuseppe Ronzitti, Sean M. Armour, Sébastien Lacroix‐Desmazes, Federico Mingozzi - Nature Medicine 2020 cited by 319
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
Authors: Albert M. Maguire, Francesca Simonelli, Eric A. Pierce, Edward N. Pugh, Federico Mingozzi, Jeannette Bennicelli, Sandro Banfi, Kathleen Marshall, Francesco Testa, Enrico Maria Surace, Settimio Rossi, Arkady Lyubarsky, Valder R. Arruda, Barbara A. Konkle, Edwin M. Stone, Junwei Sun, Jonathan B. Jacobs, Lou F Dell'Osso, Richard W. Hertle, Jian‐xing Ma, T. Michael Redmond, Xiaosong Zhu, Bernd Hauck, Olga Zelenaia, Kenneth S. Shindler, Maureen G. Maguire, J. Fraser Wright, Nicholas J. Volpe, Jennifer Wellman McDonnell, Alberto Auricchio, Katherine A. High, Jean Bennett - New England Journal of Medicine 2008 cited by 2,137
- CD8+ T-cell responses to adeno-associated virus capsid in humans
Authors: Federico Mingozzi, Marcela V. Maus, Daniel J. Hui, Denise E. Sabatino, Samuel L. Murphy, John E.J. Rasko, Margaret V. Ragni, Catherine S. Manno, Jürg M. Sommer, Haiyan Jiang, Glenn F. Pierce, Hildegund C.J. Ertl, Katherine A. High - Nature Medicine 2007 cited by 726
- Human Immune Responses to Adeno-Associated Virus (AAV) Vectors
Authors: Giuseppe Ronzitti, David‐Alexandre Gross, Federico Mingozzi - Frontiers in Immunology 2020 cited by 344
- Multiyear Factor VIII Expression after AAV Gene Transfer for Hemophilia A
Authors: Lindsey A. George, Paul E. Monahan, M. Elaine Eyster, Spencer K. Sullivan, Margaret V. Ragni, Stacy E. Croteau, John E.J. Rasko, Michael Recht, Benjamin J. Samelson‐Jones, Amy MacDougall, Kristen Jaworski, Robert Noble, Marla Curran, Klaudia Kuranda, Federico Mingozzi, Tiffany Chang, Kathleen Z. Reape, Xavier M. Anguela, Katherine A. High - New England Journal of Medicine 2021 cited by 253
- Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses
Authors: Ying Chan, Sean K. Wang, Colin J. Chu, David A. Copland, Alexander J. Letizia, Helena Costa Verdera, Jessica J. Chiang, Meher Sethi, May K. Wang, William J. Neidermyer, Yingleong Chan, Elaine T. Lim, Amanda Graveline, Melinda Sanchez, Ryan F. Boyd, Thomas S. Vihtelic, Rolando Gian Carlo O. Inciong, Jared M. Slain, Priscilla J. Alphonse, Yunlu Xue, Lindsey R. Robinson‐McCarthy, Jenny M. Tam, Maha Jabbar, Bhubanananda Sahu, Janelle Fassbender Adeniran, Manish Muhuri, Phillip W.L. Tai, Jun Xie, Tyler B. Krause, Andyna Vernet, Matthew J. Pezone, Ru Xiao, Tina Liu, Wei Wang, Henry J. Kaplan, Guangping Gao, Andrew D. Dick, Federico Mingozzi, Maureen A. McCall, Constance L. Cepko, George M. Church - Science Translational Medicine 2021 cited by 207
- Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration
Authors: Amine Meliani, Florence Boisgérault, Romain Hardet, Solenne Marmier, Fanny Collaud, Giuseppe Ronzitti, Christian Leborgne, Helena Costa Verdera, Marcelo Simon Sola, Séverine Charles, Alban Vignaud, Laetitia van Wittenberghe, Giorgia Manni, Olivier D. Christophe, Francesca Fallarino, Christopher Roy, Alicia Michaud, Petr O. Ilyinskii, Takashi Kishimoto, Federico Mingozzi - Nature Communications 2018 cited by 254
- Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia B
Authors: Lindsey A. George, Margaret V. Ragni, John E.J. Rasko, Leslie Raffini, Benjamin J. Samelson‐Jones, Margareth C. Ozelo, Maria Hazbon, Alexa R. Runowski, Jennifer Wellman, Katie Wachtel, Yifeng Chen, Xavier M. Anguela, Klaudia Kuranda, Federico Mingozzi, Katherine A. High - Molecular Therapy 2020 cited by 209
- Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial
Authors: Albert M. Maguire, Katherine A. High, Alberto Auricchio, J. Fraser Wright, Eric A. Pierce, Francesco Testa, Federico Mingozzi, Jeannette Bennicelli, Gui‐Shuang Ying, Settimio Rossi, Ann Fulton, Kathleen Marshall, Sandro Banfi, Daniel C. Chung, Jessica I. W. Morgan, Bernd Hauck, Olga Zelenaia, Xiaosong Zhu, Leslie Raffini, Frauke Coppieters, Elfride De Baere, Kenneth S. Shindler, Nicholas J. Volpe, Enrico Maria Surace, Carmela Acerra, Arkady Lyubarsky, T. Michael Redmond, Edwin M. Stone, Junwei Sun, Jennifer Wellman McDonnell, Bart P. Leroy, Francesca Simonelli, Jean Bennett - The Lancet 2009 cited by 858
- Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
Authors: Federico Mingozzi, Katherine A. High - Nature Reviews Genetics 2011 cited by 901
- Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial
Authors: Jean Bennett, Jennifer Wellman, Kathleen Marshall, Sarah McCague, Manzar Ashtari, Julie DiStefano‐Pappas, Okan U. Elci, Daniel C. Chung, Junwei Sun, J. Fraser Wright, Dominique Cross, Puya Aravand, Laura Cyckowski, Jeannette Bennicelli, Federico Mingozzi, Alberto Auricchio, Eric A. Pierce, Jason Ruggiero, Bart P. Leroy, Francesca Simonelli, Katherine A. High, Albert M. Maguire - The Lancet 2016 cited by 456
- Pre-existing humoral immunity and complement pathway contribute to immunogenicity of adeno-associated virus (AAV) vector in human blood
Authors: Corinne J. Smith, Nikki L. Ross, Ali Kamal, Kevin Y. Kim, Elizabeth Kropf, Pascal Deschatelets, Cedric Francois, William J. Quinn, Inderpal Singh, Anna Majowicz, Federico Mingozzi, Klaudia Kuranda - Frontiers in Immunology 2022 cited by 81
- Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys
Authors: Federico Mingozzi, Xavier M. Anguela, Giulia Pavani, Yifeng Chen, Robert J. Davidson, Daniel J. Hui, Mustafa N. Yazicioglu, Liron Elkouby, Christian Hinderer, Armida Faella, Carolann Howard, Alex Tai, Gregory M. Podsakoff, Shangzhen Zhou, Etiena Basner‐Tschakarjan, J. Fraser Wright, Katherine A. High - Science Translational Medicine 2013 cited by 344
- Influence of Pre-existing Anti-capsid Neutralizing and Binding Antibodies on AAV Vector Transduction
Authors: Zachary Fitzpatrick, Christian Leborgne, Elena Barbon, Elisa Masat, Giuseppe Ronzitti, Laetitia van Wittenberghe, Alban Vignaud, Fanny Collaud, Séverine Charles, Marcelo Simon Sola, F. Jouen, Olivier Boyer, Federico Mingozzi - Molecular Therapy — Methods & Clinical Development 2018 cited by 197
- Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy
Authors: Haiyan Jiang, Linda B. Couto, Susannah Patarroyo‐White, Tongyao Liu, Dea Nagy, Joseph Vargas, Shangzhen Zhou, Ciaran D. Scallan, Jürg M. Sommer, Sharmila Vijay, Federico Mingozzi, Katherine A. High, Glenn F. Pierce - Blood 2006 cited by 320
- AAV-1–mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells
Authors: Federico Mingozzi, J. J. M. Meulenberg, Daniel J. Hui, Etiena Basner‐Tschakarjan, Nicole C. Hasbrouck, Shyrie Edmonson, Natalie A. Hutnick, Michael R. Betts, John J.P. Kastelein, Erik S.G. Stroes, Katherine A. High - Blood 2009 cited by 284
- Assessing the potential for AAV vector genotoxicity in a murine model
Authors: Hojun Li, Nirav Malani, Shari R Hamilton, Alexander Schlachterman, Giulio Bussadori, Shyrie E. Edmonson, Rachel Shah, Valder R. Arruda, Federico Mingozzi, J. Fraser Wright, Frederic D. Bushman, Katherine A. High - Blood 2010 cited by 228
- Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial
Authors: Céline Vandamme, Oumeya Adjali, Federico Mingozzi - Human Gene Therapy 2017 cited by 219
