David C. Linch
Active 1980–2025
- 119
- Papers
- 28,915
- Citations
- 89
- h-index
- 119
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine71.7%
- Biochemistry, Genetics and Molecular Biology21.9%
- Immunology and Microbiology4.4%
- Neuroscience0.5%
- Computer Science0.2%
- Engineering0.2%
- Other1.1%
Topics
- Acute Myeloid Leukemia Research8.7%
- CAR-T cell therapy research6.9%
- Lymphoma Diagnosis and Treatment6.6%
- Virus-based gene therapy research4.7%
- Acute Lymphoblastic Leukemia research3.3%
- Hematopoietic Stem Cell Transplantation3.3%
- Other66.5%
Coauthors
- Rosemary E. Gale40
- Alan K. Burnett21
- Anthony H. Goldstone20
- Robert K. Hills20
- Stephen Mackinnon17
- Karl S. Peggs16
- David Cunningham15
- Panagiotis Kottaridis13
- Donald Milligan11
- Christopher Allen10
- John Radford10
- Paul Smith10
- Rajesh Chopra10
- Kwee Yong9
- Marc R. Mansour9
- Ronjon Chakraverty9
- Anne Parker8
- Kirit M. Ardeshna8
- Kirsty Thomson8
- Asim Khwaja7
- Barry W. Hancock7
- Emma Morris7
- G Hale7
- Herman Waldmann7
All papers
- Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
Authors: Amit C. Nathwani, Edward G. D. Tuddenham, Savita Rangarajan, Cecilia Rosales, Jenny McIntosh, David C. Linch, Pratima Chowdary, Anne Riddell, Arnulfo Pie, Chris F. Harrington, James O’Beirne, Keith Smith, John Pasi, Bertil Glader, Pradip K. Rustagi, Catherine Y. Ng, Mark A. Kay, Junfang Zhou, Yunyu Spence, Christopher L. Morton, James A. Allay, John B. Coleman, Susan Sleep, John M. Cunningham, Deo Kumar Srivastava, Etiena Basner‐Tschakarjan, Federico Mingozzi, Katherine A. High, John T. Gray, Ulrike M. Reiss, Arthur W. Nienhuis, Andrew M. Davidoff - New England Journal of Medicine 2011 cited by 1,843
- Salvage Regimens With Autologous Transplantation for Relapsed Large B-Cell Lymphoma in the Rituximab Era
Authors: Christian Gisselbrecht, Bertram Glaß, Nicolas Mounier, Devinder Gill, David C. Linch, Marek Trněný, André Bosly, Nicolas Ketterer, Ofer Shpilberg, Hans Hagberg, Dávid Ma, Josette Brière, Craig H. Moskowitz, Norbert Schmitz - Journal of Clinical Oncology 2010 cited by 1,622
- Assessment of Minimal Residual Disease in Standard-Risk AML
Authors: Adam Ivey, Robert K. Hills, Michael A. Simpson, Jelena Jovanović, Amanda Gilkes, Angela Grech, Yashma Patel, Neesa Bhudia, Hassan Farah, Joanne Mason, Kerry Wall, Susanna Akiki, Mike Griffiths, Ellen Solomon, Frank McCaughan, David C. Linch, Rosemary E. Gale, Paresh Vyas, Sylvie Freeman, Nigel H. Russell, Alan K. Burnett, David Grimwade - New England Journal of Medicine 2016 cited by 836
- Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
Authors: Steven J. Howe, Marc R. Mansour, Kerstin Schwarzwaelder, Cynthia C. Bartholomae, Michael Hubank, Helena Kempski, Martijn H. Brugman, Karin Pike‐Overzet, S Chatters, Dick de Ridder, Kimberly Gilmour, Stuart Adams, Susannah I. Thornhill, Kathryn L. Parsley, Frank J. T. Staal, Rosemary E. Gale, David C. Linch, Jinhua Bayford, Lucie Brown, Michelle Quaye, Christine Kinnon, Philip Ancliff, David Webb, Manfred Schmidt, Christof von Kalle, H. Bobby Gaspar, Adrian J. Thrasher - Journal of Clinical Investigation 2008 cited by 1,282
- A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy
Authors: Brian Philip, Evangelia Kokalaki, Leila Mekkaoui, Simon Thomas, Karin Straathof, Barry Flutter, Virna Marin, Teresa Marafioti, Ronjon Chakraverty, David C. Linch, Sergio A. Quezada, Karl S. Peggs, Martin Pulé - Blood 2014 cited by 401
- Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
Authors: Claire Roddie, Juliana Dias, Maeve O’Reilly, Mahnaz Abbasian, Amaia Cadiñanos-Garai, Ketki Vispute, Leticia Bosshard‐Carter, Marina Mitsikakou, Vedika Mehra, Harriet Roddy, John A. Hartley, Victoria J. Spanswick, Helen L. Lowe, Bilyana Popova, Laura Clifton‐Hadley, Graham Wheeler, Joanna Olejnik, Adrian Bloor, David Irvine, L. Wood, Maria A. V. Marzolini, Sabine Domning, Farzin Farzaneh, Mark W. Lowdell, David C. Linch, Martin Pulé, Karl S. Peggs - Journal of Clinical Oncology 2021 cited by 142
- Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies
Authors: Paul Maciocia, Patrycja Wawrzyniecka, Brian Philip, Ida Ricciardelli, Ayse U. Akarca, Shimobi Onuoha, Mateusz Legut, David K. Cole, Andrew K. Sewell, Giuseppe Gritti, Joan Somja, Miguel Á. Piris, Karl S. Peggs, David C. Linch, Teresa Marafioti, Martin Pulé - Nature Medicine 2017 cited by 283
- Acute myeloid leukaemia
Authors: Asim Khwaja, Magnus Björkholm, Rosemary E. Gale, Ross L. Levine, Craig T. Jordan, Gerhard Ehninger, Clara D. Bloomfield, Eli Estey, Alan K. Burnett, Jan J. Cornelissen, David A. Scheinberg, Didier Bouscary, David C. Linch - Nature Reviews Disease Primers 2016 cited by 587
- Dual targeting of CD19 and CD22 with Bicistronic CAR-T cells in Patients with Relapsed/Refractory Large B Cell Lymphoma
Authors: Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay Peddareddigari, Nushmia Z. Khokhar, Robert W. Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Lihua E. Budde, Connie Lee Batlevi, Nancy L. Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin Pulé - Blood 2023 cited by 70
- Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles
Authors: David Cunningham, Eliza A. Hawkes, Andrew Jack, Wendi Qian, Paul Smith, Paul Mouncey, Christopher Pocock, Kirit M. Ardeshna, John Radford, Andrew McMillan, John Davies, Deborah Turner, Anton Kruger, Peter Johnson, Joanna Gambell, David C. Linch - The Lancet 2013 cited by 556
- Outcome of patients with relapsed diffuse large B-cell lymphoma who fail second-line salvage regimens in the International CORAL study
Authors: Éric Van Den Neste, Norbert Schmitz, Nicolas Mounier, Devinder Gill, David C. Linch, Marek Trněný, Nöel Milpied, John Radford, Nicolas Ketterer, Ofer Shpilberg, Ulrich Dührsen, Dávid Ma, Josette Brière, Catherine Thiéblemont, Gilles Salles, Craig H. Moskowitz, B. Glaß, Christian Gisselbrecht - Bone Marrow Transplantation 2015 cited by 316
- The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
Authors: Panagiotis Kottaridis, Rosemary E. Gale, Marion E. Frew, G Harrison, Stephen E. Langabeer, Andrea A. Belton, Helen M. Walker, Keith Wheatley, David Bowen, Alan K. Burnett, Anthony H. Goldstone, David C. Linch - Blood 2001 cited by 1,538
- The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
Authors: Rosemary E. Gale, Claire Green, Christopher Allen, Adam J. Mead, Alan K. Burnett, Robert K. Hills, David C. Linch - Blood 2007 cited by 744
- Rituximab versus a watch-and-wait approach in patients with advanced-stage, asymptomatic, non-bulky follicular lymphoma: an open-label randomised phase 3 trial
Authors: Kirit M. Ardeshna, Wendi Qian, Paul Smith, Nivette Braganca, Lisa Lowry, Pip Patrick, June Warden, Lindsey Stevens, Christopher Pocock, Fiona Miall, David Cunningham, John Davies, Andrew Jack, Richard Stephens, Jan Walewski, Burhan Ferhanoğlu, Ken Bradstock, David C. Linch - The Lancet Oncology 2014 cited by 388
- Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients
Authors: Friederike Christen, Kaja Hoyer, Kenichi Yoshida, Hsin‐An Hou, Nils Waldhueter, Michael Heuser, Robert K. Hills, Willy Chan, Raphael Hablesreiter, Olga Blau, Yotaro Ochi, Piroska Klement, Wen‐Chien Chou, Igor‐Wolfgang Blau, Jih‐Luh Tang, Tomasz Żemojtel, Yuichi Shiraishi, Yusuke Shiozawa, Felicitas Thol, Arnold Ganser, Bob Löwenberg, David C. Linch, Lars Bullinger, Peter J.M. Valk, Hwei‐Fang Tien, Rosemary E. Gale, Seishi Ogawa, Frédérik Damm - Blood 2019 cited by 139
- Reduced dose radiotherapy for local control in non-Hodgkin lymphoma: A randomised phase III trial
Authors: Lisa Lowry, Paul Smith, Wendi Qian, Stephen Falk, Kim Benstead, Tim Illidge, David C. Linch, Martin Robinson, Andrew Jack, Peter Hoskin - Radiotherapy and Oncology 2011 cited by 386
- Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study
Authors: Alvina G. Lai, Laura Pasea, Amitava Banerjee, Geoff Hall, Spiros Denaxas, Wai Hoong Chang, Michail Katsoulis, Bryan Williams, Deenan Pillay, Mahdad Noursadeghi, David C. Linch, Derralynn Hughes, Martin Förster, Clare Turnbull, Natalie Fitzpatrick, Kathryn Boyd, Graham R. Foster, Tariq Enver, Vahé Nafilyan, Ben Humberstone, Richard D Neal, Matt Cooper, Monica Jones, Kathy Pritchard‐Jones, Richard Sullivan, Charlie Davie, Mark Lawler, Harry Hemingway - BMJ Open 2020 cited by 329
- Dose intensification with autologous bone-marrow transplantation in relapsed and resistant Hodgkin's disease: results of a BNLI randomised trial
Authors: David C. Linch, A. H. Goldstone, Annabel McMillan, Rajesh Chopra, G. Vaughan Hudson, D.A. Winfield, Barry W. Hancock, D. J. Moir, D Milligan - The Lancet 1993 cited by 1,050
- Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia
Authors: Sunniyat Rahman, Michael Magnussen, Theresa E. León, Nadine Farah, Zhaodong Li, Brian J. Abraham, Krisztina Zuborne Alapi, Rachel J. Mitchell, Tom Naughton, Adele K. Fielding, Arnold Pizzey, Sophia Bustraan, Christopher Allen, Teodora Popa, Karin Pike‐Overzet, Laura García-Pérez, Rosemary E. Gale, David C. Linch, Frank J. T. Staal, Richard A. Young, A. Thomas Look, Marc R. Mansour - Blood 2017 cited by 80
- Genome-wide association study identifies susceptibility loci for acute myeloid leukemia
Authors: Wei‐Yu Lin, Sarah Fordham, Eric A. Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne S. Quante, Konstantin Strauch, Christian Gieger, Andrew D. Skol, Thahira Rahman, Lara E. Sucheston‐Campbell, Junke Wang, Theresa Hahn, Alyssa Clay‐Gilmour, Gail Jones, Helen Marr, Graham Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desireé Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette Klarskov Andersen, Maria Chiara Fontana, Giovanni Martinelli, Giovanni Marconi, Miguel Á. Sanz, José Cervera, Inés Gómez‐Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo‐Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David C. Linch, Julia Gaal-Wesinger, András Masszi, Daniel Nowak, Wolf‐Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Róbert Královics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan - Nature Communications 2021 cited by 43
- EZH2 -Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress
Authors: Theresa E. León, Tanya Rapoz-D’Silva, Cosetta Bertoli, Sunniyat Rahman, Michael Magnussen, Brian Philip, Nadine Farah, Simon Richardson, Sara Ahrabi, José Afonso Guerra‐Assunção, Rajeev Gupta, Elisabeth P. Nacheva, Stephen Henderson, Javier Herrero, David C. Linch, Robertus A.M. de Bruin, Marc R. Mansour - Cancer Discovery 2020 cited by 40
- Rituximab Maintenance Therapy After Autologous Stem-Cell Transplantation in Patients With Relapsed CD20+ Diffuse Large B-Cell Lymphoma: Final Analysis of the Collaborative Trial in Relapsed Aggressive Lymphoma
Authors: Christian Gisselbrecht, Norbert Schmitz, Nicolas Mounier, Devinder Gill, David C. Linch, Marek Trněný, André Bosly, Nöel Milpied, John Radford, Nicolas Ketterer, Ofer Shpilberg, Ulrich Dührsen, Hans Hagberg, Daniel David, Andreas Viardot, Ray M. Lowenthal, Josette Brière, Gilles Salles, Craig H. Moskowitz, Bertram Glaß - Journal of Clinical Oncology 2012 cited by 273
- TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis
Authors: David Bowen, Michael J. Groves, Alan K. Burnett, Yashma Patel, Christopher Allen, C Green, Rosemary E. Gale, Robert K. Hills, David C. Linch - Leukemia 2008 cited by 210
- De Novo Treatment of Diffuse Large B-Cell Lymphoma With Rituximab, Cyclophosphamide, Vincristine, Gemcitabine, and Prednisolone in Patients With Cardiac Comorbidity: A United Kingdom National Cancer Research Institute Trial
Authors: Paul Fields, William Townsend, Andrew Webb, Nicholas Counsell, Christopher Pocock, Paul Smith, Andrew Jack, Nadjet El-Mehidi, Peter Johnson, John Radford, David C. Linch, David Cunnningham - Journal of Clinical Oncology 2013 cited by 101
