Frank McCormick
Active 1980–2025
- 288
- Papers
- 84,666
- Citations
- 145
- h-index
- 281
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology57.7%
- Medicine34%
- Immunology and Microbiology2.5%
- Neuroscience1.8%
- Computer Science0.8%
- Agricultural and Biological Sciences0.5%
- Other2.7%
Topics
- Protein Kinase Regulation and GTPase Signaling4.7%
- PI3K/AKT/mTOR signaling in cancer2.5%
- Cancer-related Molecular Pathways2.4%
- Wnt/β-catenin signaling in development and cancer2.3%
- Melanoma and MAPK Pathways1.9%
- Epigenetics and DNA Methylation1.8%
- Other84.4%
Coauthors
- Dwight V. Nissley29
- Dominic Esposito27
- Dhirendra K. Simanshu26
- Andrew G. Stephen22
- Joshua D. Harris15
- David M. Jablons14
- Liang You13
- Simon Messing13
- Zhidong Xu13
- Biao He12
- Dana Rabara11
- Geoffrey D. Abrams11
- Srisathiyanarayanan Dharmaiah11
- Timothy H. Tran11
- Patrick Alexander10
- Pau Castel10
- Robin Clark10
- Yue Yang10
- Bernard R. Bach9
- George A. Martin9
- William Gillette9
- Amie Y. Lee8
- Brian J. Cole8
- David Stokoe8
All papers
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
Authors: Francisco Sánchez-Vega, Marco Mina, Joshua Armenia, Walid K. Chatila, Augustin Luna, Konnor La, Sofia Dimitriadoy, David L. Liu, Havish S. Kantheti, Sadegh Saghafinia, Debyani Chakravarty, Foysal Daian, Qingsong Gao, Matthew H. Bailey, Wen-Wei Liang, Steven M. Foltz, Ilya Shmulevich, Li Ding, Zachary Heins, Angelica Ochoa, Benjamin Groß, Galen F. Gao, Hongxin Zhang, Ritika Kundra, Cyriac Kandoth, Istemi Bahceci, Leonard Dervishi, Uğur Doğrusöz, Wanding Zhou, Hui Shen, Peter W. Laird, Gregory P. Way, Casey S. Greene, Han Liang, Yonghong Xiao, Chen Wang, Antonio Iavarone, Alice H. Berger, Trever G. Bivona, Alexander J. Lazar, Gary D. Hammer, Thomas J. Giordano, Lawrence N. Kwong, Grant A. McArthur, Chenfei Huang, Aaron D. Tward, Mitchell J. Frederick, Frank McCormick, Matthew Meyerson, Rory Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy Defreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Jaegil Kim, Michael S. Lawrence, Pei Lin, Sam Meier, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila M. Reynolds, Ilya Shmulevich, Vésteinn Thórsson, Wei Zhang, Rehan Akbani, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Rupa S. Kanchi and 679 more - Cell 2018 cited by 3,424
- Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Authors: Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan, Dhruv Bole, John K. Eaton, Alexandre Matov, Jacqueline Galeas, Harshil Dhruv, Michael E. Berens, Stuart L. Schreiber, Frank McCormick, Michael T. McManus - Nature 2017 cited by 1,804
- RAS Proteins and Their Regulators in Human Disease
Authors: Dhirendra K. Simanshu, Dwight V. Nissley, Frank McCormick - Cell 2017 cited by 1,975
- RAS-targeted therapies: is the undruggable drugged?
Authors: Amanda R. Moore, Scott Rosenberg, Frank McCormick, Shiva Malek - Nature Reviews Drug Discovery 2020 cited by 1,070
- The metabolic landscape of RAS-driven cancers from biology to therapy
Authors: Suman Mukhopadhyay, Matthew G. Vander Heiden, Frank McCormick - Nature Cancer 2021 cited by 354
- A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
Authors: Richard M. Neve, Koei Chin, Jane Fridlyand, Jennifer Yeh, Frederick L. Baehner, Tea Fevr, Laura Ashley Clark, Nora Bayani, Jean‐Philippe Coppé, Frances Tong, Terry Speed, Paul T. Spellman, Sandy DeVries, Anna Lapuk, N. Wang, Wen‐Lin Kuo, Jackie L. Stilwell, Daniel Pinkel, Donna G. Albertson, Frederic M. Waldman, Frank McCormick, Robert B. Dickson, Michael D. Johnson, Marc E. Lippman, Stephen P. Ethier, Adi F. Gazdar, Joe W. Gray - Cancer Cell 2006 cited by 3,231
- Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
Authors: Luika Timmerman, Thomas Holton, Mariia Yuneva, Raymond J. Louie, Mercè Padró, Anneleen Daemen, Min Hu, Denise A. Chan, Stephen P. Ethier, Laura van ‘t Veer, Kornélia Polyák, Frank McCormick, Joe W. Gray - Cancer Cell 2013 cited by 570
- Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
Authors: Khyati N. Shah, Roma Bhatt, Julia Rotow, Julia Rohrberg, Victor Olivas, Victoria E. Wang, Golzar Hemmati, Maria M. Martins, Ashley Maynard, Jonathan Kuhn, Jacqueline Galeas, Hayley Donnella, Swati Kaushik, Angel A. Ku, Sophie Dumont, Gregor Krings, Henry J. Haringsma, Liliane Robillard, Andrew D. Simmons, Thomas C. Harding, Frank McCormick, Andrei Goga, Collin M. Blakely, Trever G. Bivona, Sourav Bandyopadhyay - Nature Medicine 2018 cited by 286
- Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond
Authors: Matthew Holderfield, Marian M. Deuker, Frank McCormick, Martin McMahon - Nature reviews. Cancer 2014 cited by 827
- Undermining Glutaminolysis Bolsters Chemotherapy While NRF2 Promotes Chemoresistance in KRAS-Driven Pancreatic Cancers
Authors: Suman Mukhopadhyay, Debanjan Goswami, Pavan P. Adiseshaiah, William Burgan, Ming Yi, Theresa M. Guerin, С. В. Козлов, Dwight V. Nissley, Frank McCormick - Cancer Research 2020 cited by 315
- The RB and p53 pathways in cancer
Authors: Charles J. Sherr, Frank McCormick - Cancer Cell 2002 cited by 1,667
- Dragging Ras Back in the Ring
Authors: Andrew G. Stephen, Dominic Esposito, Rachel Bagni, Frank McCormick - Cancer Cell 2014 cited by 803
- Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
Authors: Luika Timmerman, Joaquím Grego‐Bessa, Ángel Raya, Esther Bertrán, José M. Pérez‐Pomares, Juan Díez, Sergi Aranda, Sergio Palomo‐Ponce, Frank McCormick, Juan Carlos Izpisúa‐Belmonte, José Luís de la Pompa - Genes & Development 2003 cited by 982
- Structure–function analysis of the SHOC2–MRAS–PP1C holophosphatase complex
Authors: Jason J. Kwon, Behnoush Hajian, Yuemin Bian, Lucy C. Young, Alvaro J. Amor, James R. Fuller, Cara V. Fraley, Abbey M. Sykes, Jonathan So, Joshua Pan, Laura Baker, Sun Joo Lee, Douglas B. Wheeler, David L. Mayhew, Nicole S. Persky, Xiaoping Yang, David E. Root, Anthony M. Barsotti, Andrew W. Stamford, Charles K. Perry, Alex B. Burgin, Frank McCormick, Christopher T. Lemke, William C. Hahn, Andrew J. Aguirre - Nature 2022 cited by 85
- The GTPase superfamily: conserved structure and molecular mechanism
Authors: Henry R. Bourne, D.A.R. Sanders, Frank McCormick - Nature 1991 cited by 3,409
- β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
Authors: Osamu Tetsu, Frank McCormick - Nature 1999 cited by 3,607
- An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells
Authors: James R. Bischoff, David H. Kirn, Angelica Williams, Carla Heise, Sharon T. Horn, Mike Muna, Lelia Ng, Julie A. Nye, Adam Sampson-Johannes, Ali Fattaey, Frank McCormick - Science 1996 cited by 1,762
- ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications
Authors: Ming Yi, Dwight V. Nissley, Frank McCormick, Robert M. Stephens - Scientific Reports 2020 cited by 255
- Machine learning–driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins
Authors: Helgi I. Ingólfsson, Chris Neale, Timothy S. Carpenter, Rebika Shrestha, César A. López, Timothy H. Tran, Tomas Oppelstrup, Harsh Bhatia, Liam Stanton, Xiaohua Zhang, Shiv Sundram, Francesco Di Natale, Animesh Agarwal, Gautham Dharuman, Sara Kokkila-Schumacher, Thomas J. Turbyville, Gülçin Gülten, Que N. Van, Debanjan Goswami, Frantz Jean-François, Constance Agamasu, De Chen, Jeevapani J. Hettige, Timothy Travers, Sumantra Sarkar, Michael P. Surh, Yue Yang, Adam Moody, Shusen Liu, Brian C. Van Essen, Arthur F. Voter, Arvind Ramanathan, Nicolas Hengartner, Dhirendra K. Simanshu, Andrew G. Stephen, Peer‐Timo Bremer, S. Gnanakaran, James N. Glosli, Felice C. Lightstone, Frank McCormick, Dwight V. Nissley, Frederick H. Streitz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 87
- More to the RAS Story: KRASG12C Inhibition, Resistance Mechanisms, and Moving Beyond KRASG12C
Authors: Caressa Lietman, Melissa L. Johnson, Frank McCormick, Colin R. Lindsay - American Society of Clinical Oncology Educational Book 2022 cited by 37
- Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator
Authors: Seiko Ishida, Frank McCormick, Karen Smith‐McCune, Douglas Hanahan - Cancer Cell 2010 cited by 287
- Adenovirus E4ORF1-Induced MYC Activation Promotes Host Cell Anabolic Glucose Metabolism and Virus Replication
Authors: Minh Thai, Nicholas A. Graham, Daniel Braas, Michael Nehil, Evangelia Komisopoulou, Siavash K. Kurdistani, Frank McCormick, Thomas G. Graeber, Heather R. Christofk - Cell Metabolism 2014 cited by 281
- KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis
Authors: Dana Rabara, Timothy H. Tran, Srisathiyanarayanan Dharmaiah, Robert M. Stephens, Frank McCormick, Dhirendra K. Simanshu, Matthew Holderfield - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 129
- Structure of the SHOC2–MRAS–PP1C complex provides insights into RAF activation and Noonan syndrome
Authors: Daniel A. Bonsor, Patrick Alexander, Kelly Snead, Nicole Hartig, Matthew Drew, Simon Messing, Lorenzo I. Finci, Dwight V. Nissley, Frank McCormick, Dominic Esposito, Pablo Rodriguez‐Viciana, Andrew G. Stephen, Dhirendra K. Simanshu - Nature Structural & Molecular Biology 2022 cited by 52
