Henry R. Bourne
Active 1970–2007
- 115
- Papers
- 35,660
- Citations
- 97
- h-index
- 115
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology63.5%
- Medicine18.6%
- Neuroscience7.7%
- Immunology and Microbiology4.3%
- Engineering1.2%
- Agricultural and Biological Sciences1.1%
- Other3.6%
Topics
- Receptor Mechanisms and Signaling6.5%
- Protein Kinase Regulation and GTPase Signaling5.7%
- Cellular transport and secretion3.3%
- Cellular Mechanics and Interactions2.6%
- Neuropeptides and Animal Physiology2.3%
- Neuroscience and Neuropharmacology Research2.1%
- Other77.5%
Coauthors
- Bruce R. Conklin10
- Kenneth L. Melmon10
- Paul Herzmark8
- Susan B. Masters8
- Taroh Iiri8
- Orion D. Weiner7
- Zvi Farfel7
- Fei Wang6
- Kathleen A. Sullivan6
- Olivier Lichtarge6
- Alexandra Van Keymeulen5
- B Beiderman5
- Elaine C. Meng5
- F H Chang5
- Frank McCormick5
- Gordon M. Tomkins5
- Harvey R. Kaslow5
- Lawrence M. Lichtenstein5
- Philip Coffino5
- Ann M. Pace4
- Cornelis Van Dop4
- Gary L. Johnson4
- Guy Servant4
- Lubert Stryer4
All papers
- Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
Authors: Min Zhao, Bing Song, Jin Pu, Teiji Wada, Brian Reid, Guangping Tai, Fei Wang, Aihua Guo, Petr Walczysko, Yu Gu, Takehiko Sasaki, Akira Suzuki, John V. Forrester, Henry R. Bourne, Peter N. Devreotes, Colin McCaig, Josef Penninger - Nature 2006 cited by 1,180
- The GTPase superfamily: conserved structure and molecular mechanism
Authors: Henry R. Bourne, D.A.R. Sanders, Frank McCormick - Nature 1991 cited by 3,409
- GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours
Authors: Claudia A. Landis, Susan B. Masters, Anna Spada, Ann M. Pace, Henry R. Bourne, Lucia Vallar - Nature 1989 cited by 1,452
- The GTPase superfamily: a conserved switch for diverse cell functions
Authors: Henry R. Bourne, D.A.R. Sanders, Frank McCormick - Nature 1990 cited by 2,357
- Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
Authors: Bruce R. Conklin, Zvi Farfel, Kevin D. Lustig, David Julius, Henry R. Bourne - Nature 1993 cited by 739
- Divergent Signals and Cytoskeletal Assemblies Regulate Self-Organizing Polarity in Neutrophils
Authors: Jingsong Xu, Fei Wang, Alexandra Van Keymeulen, Paul Herzmark, Aaron F. Straight, Kathleen Kelly, Yoh Takuwa, Naotoshi Sugimoto, Timothy J. Mitchison, Henry R. Bourne - Cell 2003 cited by 700
- Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis
Authors: S R Srinivasan, Fei Wang, Suzana Glavas, Alexander Ott, Fred Hofmann, Klaus Aktories, Daniel Kalman, Henry R. Bourne - The Journal of Cell Biology 2003 cited by 481
- Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis
Authors: Orion D. Weiner, Maike Rentel, Alex Ott, Glenn E. Brown, Mark P. Jedrychowski, Michael B. Yaffe, Steven P. Gygi, Lewis C. Cantley, Henry R. Bourne, Marc W. Kirschner - PLoS Biology 2006 cited by 185
- An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families
Authors: Olivier Lichtarge, Henry R. Bourne, Fred E. Cohen - Journal of Molecular Biology 1996 cited by 1,224
- Polarization of Chemoattractant Receptor Signaling During Neutrophil Chemotaxis
Authors: Guy Servant, Orion D. Weiner, Paul Herzmark, Tamás Balla, John W. Sedat, Henry R. Bourne - Science 2000 cited by 892
- A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
Authors: Orion D. Weiner, Paul O. Neilsen, Glenn D. Prestwich, Marc W. Kirschner, Lewis C. Cantley, Henry R. Bourne - Nature Cell Biology 2002 cited by 513
- Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha.
Authors: Philip Wedegaertner, David H. Chu, Paul T. Wilson, Mark J. Levis, Henry R. Bourne - Journal of Biological Chemistry 1993 cited by 299
- Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils
Authors: Fei Wang, Paul Herzmark, Orion D. Weiner, S R Srinivasan, Guy Servant, Henry R. Bourne - Nature Cell Biology 2002 cited by 473
- Rapid GDP release from Gsα in patients with gain and loss of endocrine function
Authors: Taroh Iiri, Paul Herzmark, Jon M. Nakamoto, Cornells Van Dop, Henry R. Bourne - Nature 1994 cited by 297
- Spatial control of actin polymerization during neutrophil chemotaxis
Authors: Orion D. Weiner, Guy Servant, Matthew D. Welch, Timothy J. Mitchison, John W. Sedat, Henry R. Bourne - Nature Cell Biology 1999 cited by 284
- Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation.
Authors: Bruce R. Conklin, Paul Herzmark, S. Ishida, T. Voyno-Yasenetskaya, Ying Sun, Zvi Farfel, Henry R. Bourne - Molecular Pharmacology 1996 cited by 182
- Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism
Authors: Kit Wong, Olivier Pertz, Klaus M. Hahn, Henry R. Bourne - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 174
- Polarity reveals intrinsic cell chirality
Authors: Jingsong Xu, Alexandra Van Keymeulen, Nicole M. Wakida, Peter M. Carlton, Michael W. Berns, Henry R. Bourne - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 156
- Two G Protein Oncogenes in Human Endocrine Tumors
Authors: John F. Lyons, Claudia A. Landis, Griffith Harsh, Lucia Vallar, Kurt Grünewald, Hans G. Feichtinger, Quan‐Yang Duh, Orlo H. Clark, Ernest S. Kawasaki, Henry R. Bourne, Frank McCormick - Science 1990 cited by 1,046
- Activation of the cloned muscarinic potassium channel by G protein βγ subunits
Authors: Eitan Reuveny, Paul A. Slesinger, James Inglese, Janine Morales, Jorge A. Iñiguez-Lluhı́, Robert J. Lefkowitz, Henry R. Bourne, Yuh Nung Jan, Lily Yeh Jan - Nature 1994 cited by 482
- G-protein diseases furnish a model for the turn-on switch
Authors: Taroh Iiri, Zvi Farfel, Henry R. Bourne - Nature 1998 cited by 197
- Lipid Modifications of Trimeric G Proteins
Authors: Philip Wedegaertner, Paul T. Wilson, Henry R. Bourne - Journal of Biological Chemistry 1995 cited by 474
- Receptors induce chemotaxis by releasing the βγ subunit of G i , not by activating G q or G s
Authors: Enid Neptune, Henry R. Bourne - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 cited by 274
- Clinical Characteristics of Acromegalic Patients whose Pituitary Tumors Contain Mutant GsProtein
Authors: Claudia A. Landis, Griffith Harsh, John S. Lyons, Richard L. Davis, Frank McCormick, Henry R. Bourne - The Journal of Clinical Endocrinology & Metabolism 1990 cited by 213
