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David Stokoe

Active 1992–2025

60
Papers
22,674
Citations
55
h-index
57
i10-index

Citations

Citations per year for David Stokoe1986: 1 citations1990: 1 citations1992: 3 citations1993: 21 citations1994: 71 citations1995: 128 citations1996: 138 citations1997: 135 citations1998: 242 citations1999: 258 citations2000: 277 citations2001: 274 citations2002: 317 citations2003: 257 citations2004: 209 citations2005: 218 citations2006: 260 citations2007: 312 citations2008: 351 citations2009: 355 citations2010: 363 citations2011: 363 citations2012: 353 citations2013: 312 citations2014: 305 citations2015: 315 citations2016: 281 citations2017: 274 citations2018: 224 citations2019: 619 citations2020: 566 citations2021: 493 citations2022: 316 citations2023: 222 citations2024: 322 citations2025: 141 citations2026: 6 citations1987–1989: no citations, so these years are not shown1991: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,343 citing papers, 37.6% of this breakdownChina: 954 citing papers, 8.3% of this breakdownUnited Kingdom: 922 citing papers, 8% of this breakdownGermany: 569 citing papers, 4.9% of this breakdownJapan: 464 citing papers, 4% of this breakdownCanada: 432 citing papers, 3.8% of this breakdownFrance: 383 citing papers, 3.3% of this breakdownItaly: 356 citing papers, 3.1% of this breakdownSwitzerland: 299 citing papers, 2.6% of this breakdownAustralia: 263 citing papers, 2.3% of this breakdownSpain: 221 citing papers, 1.9% of this breakdownNetherlands: 208 citing papers, 1.8% of this breakdown
0%37.6%Other 18.4%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology62.2%
  • Medicine29.5%
  • Immunology and Microbiology3.6%
  • Neuroscience1.5%
  • Computer Science1.1%
  • Chemistry0.6%
  • Other1.5%

Topics

  • PI3K/AKT/mTOR signaling in cancer7%
  • Protein Kinase Regulation and GTPase Signaling5.7%
  • Melanoma and MAPK Pathways4%
  • Cancer, Hypoxia, and Metabolism2.5%
  • Cancer Immunotherapy and Biomarkers2.4%
  • Glioma Diagnosis and Treatment2.3%
  • Other76.1%

Coauthors

All papers

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  1. Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

    Authors: Andrew T. Parsa, James S. Waldron, Amith Panner, Courtney A. Crane, Ian F. Parney, Jeffrey J. Barry, Kristine E. Cachola, Joseph C. Murray, Tarık Tihan, Michael C. Jensen, Paul S. Mischel, David Stokoe, Russell O. Pieper - Nature Medicine 2006 cited by 1,350

  2. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

    Authors: Georgia Hatzivassiliou, Kyung Song, Ivana Yen, Barbara J. Brandhuber, Daniel J. Anderson, Ryan Alvarado, Mary J. C. Ludlam, David Stokoe, Susan L. Gloor, Guy Vigers, Tony Morales, Ignacio Aliagas, Bonnie Liu, Steve Sideris, Klaus P. Hoeflich, Bijay S. Jaiswal, Somasekar Seshagiri, Hartmut Koeppen, Marcia Belvin, Lori S. Friedman, Shiva Malek - Nature 2010 cited by 1,638

  3. A comprehensive transcriptional portrait of human cancer cell lines

    Authors: Christiaan Klijn, Steffen Durinck, Eric Stawiski, Peter M. Haverty, Zhaoshi Jiang, Hanbin Liu, Jeremiah D. Degenhardt, Oleg Mayba, Florian Gnad, Jinfeng Liu, Grégoire Pau, Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh Selvaraj, Mamie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrušan, Richard M. Neve, Frédéric J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Zemin Zhang - Nature Biotechnology 2014 cited by 724

  4. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

    Authors: Till Maurer, Lindsay S. Garrenton, Angela Oh, Keith Pitts, Daniel J. Anderson, Nicholas J. Skelton, Benjamin P. Fauber, Borlan Pan, Shiva Malek, David Stokoe, Mary J. C. Ludlam, Krista K. Bowman, Jiansheng Wu, Anthony M. Giannetti, Melissa A. Starovasnik, Ira Mellman, Peter K. Jackson, Joachim Rudolph, Weiru Wang, Guowei Fang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 630

  5. A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

    Authors: Zachary A. Knight, Beatriz González, Morri E. Feldman, Eli R. Zunder, David Goldenberg, Olusegun Williams, Robbie Loewith, David Stokoe, András Balla, Balázs István Tóth, Tamás Balla, William A. Weiss, Roger Williams, Kevan M. Shokat - Cell 2006 cited by 1,154

  6. Diverse somatic mutation patterns and pathway alterations in human cancers

    Authors: Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson, Vasantharajan Janakiraman, Deepali Bhatt, Howard M. Stern, Peng Yue, Peter M. Haverty, Richard Bourgon, Jianbiao Zheng, Martin Moorhead, Subhra Chaudhuri, Lynn P. Tomsho, Brock A. Peters, Kanan Pujara, Shaun Cordes, David P. Davis, Victoria Carlton, Wenlin Yuan, Li Li, Weiru Wang, Charles Eigenbrot, Joshua S. Kaminker, David A. Eberhard, Paul Waring, Stephan C. Schuster, Zora Modrušan, Zemin Zhang, David Stokoe, Frédéric J. de Sauvage, Malek Faham, Somasekar Seshagiri - Nature 2010 cited by 1,034

  7. Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

    Authors: David Stokoe, Leonard R. Stephens, Terry Copeland, Piers R. J. Gaffney, Colin B. Reese, Gavin F. Painter, Andrew B. Holmes, Frank McCormick, Phillip T. Hawkins - Science 1997 cited by 1,213

  8. Structure of the p53 degradation complex from HPV16

    Authors: John Wang, Hannah T. Baddock, Amirhossein Mafi, Ian T. Foe, Matthew Bratkowski, Ting‐Yu Lin, Zena D. Jensvold, Magdalena Preciado López, David Stokoe, Dan Eaton, Qi Hao, Aaron H. Nile - Nature Communications 2024 cited by 57

  9. Loss of PTEN facilitates HIF-1-mediated gene expression

    Authors: Wayne Zundel, Cornelia Schindler, Daphne A. Haas‐Kogan, Albert C. Koong, Fiona Kaper, Eunice Y. Chen, Alexander Gottschalk, Heather E. Ryan, Randall S. Johnson, Anne B. Jefferson, David Stokoe, Amato J. Giaccia - Genes & Development 2000 cited by 833

  10. Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers

    Authors: Leonard D. Goldstein, James Lee, Florian Gnad, Christiaan Klijn, Annalisa Schaub, Jens Reeder, Anneleen Daemen, Corey E. Bakalarski, Thomas Holcomb, David S. Shames, Ryan J. Hartmaier, Juliann Chmielecki, Somasekar Seshagiri, Robert Gentleman, David Stokoe - Cell Reports 2016 cited by 211

  11. KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer

    Authors: Michael R. Burgess, Eugene Hwang, Rana Mroue, Craig M. Bielski, Anica M. Wandler, Benjamin J. Huang, Ari J. Firestone, Amy Young, Jennifer A. Lacap, Lisa Crocker, Saurabh Asthana, Elizabeth M. Davis, Jin Xu, Keiko Akagi, Michelle M. Le Beau, Qing Li, Benjamin Haley, David Stokoe, Deepak Sampath, Barry S. Taylor, Marie Evangelista, Kevin Shannon - Cell 2017 cited by 188

  12. Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

    Authors: Ingo K. Mellinghoff, Maria Y. Wang, Igor Vivanco, Daphne A. Haas‐Kogan, Shaojun Zhu, Ederlyn Q. Dia, Kan Lu, Koji Yoshimoto, Julie H. Huang, Dennis J. Chute, Bridget L. Riggs, Steve Horvath, Linda M. Liau, Webster K. Cavenee, P. Nagesh Rao, Rameen Beroukhim, Timothy C. Peck, Jeffrey C. Lee, William R. Sellers, David Stokoe, Michael D. Prados, Timothy F. Cloughesy, Charles L. Sawyers, Paul S. Mischel - New England Journal of Medicine 2005 cited by 1,448

  13. Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

    Authors: Len Stephens, Karen E. Anderson, David Stokoe, Hediye Erdjument‐Bromage, Gavin F. Painter, Andrew B. Holmes, Piers R. J. Gaffney, Colin B. Reese, Frank McCormick, Paul Tempst, John Coadwell, Phillip T. Hawkins - Science 1998 cited by 1,063

  14. Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes

    Authors: Genee Y. Lee, Peter M. Haverty, Li Li, Noelyn M. Kljavin, Richard Bourgon, James Lee, Howard M. Stern, Zora Modrušan, Somasekar Seshagiri, Zemin Zhang, David Davis, David Stokoe, Jeffrey Settleman, Frédéric J. de Sauvage, Richard M. Neve - Cancer Research 2014 cited by 163

  15. Activation of Raf as a Result of Recruitment to the Plasma Membrane

    Authors: David Stokoe, Susan G. Macdonald, Karen A. Cadwallader, Marc Symons, John F. Hancock - Science 1994 cited by 987

  16. Induction of NF-κB by the Akt/PKB kinase

    Authors: Larry Kane, Virginia Smith Shapiro, David Stokoe, Arthur Weiss - Current Biology 1999 cited by 854

  17. Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

    Authors: Michael D. Prados, Susan M. Chang, Nicholas Butowski, Rebecca DeBoer, Rupa Parvataneni, Hannah Carliner, Paul Kabuubi, Jennifer Ayers-Ringler, Jane Rabbitt, Margaretta Page, Anne Fedoroff, Penny K. Sneed, Mitchel S. Berger, Michael W. McDermott, Andrew T. Parsa, Scott R. VandenBerg, C. David James, Kathleen R. Lamborn, David Stokoe, Daphne A. Haas‐Kogan - Journal of Clinical Oncology 2008 cited by 376

  18. Akt activation by growth factors is a multiple-step process: the role of the PH domain

    Authors: Alfonso Bellacosa, Tung O. Chan, Naheed N. Ahmed, Ketaki Datta, Scott Malstrom, David Stokoe, Frank McCormick, Jinan Feng, Philip N. Tsichlis - Oncogene 1998 cited by 542

  19. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

    Authors: Qi-Wen Fan, Zachary A. Knight, David Goldenberg, Wei Yu, Keith E. Mostov, David Stokoe, Kevan M. Shokat, William A. Weiss - Cancer Cell 2006 cited by 584

  20. Disruption of PH–kinase domain interactions leads to oncogenic activation of AKT in human cancers

    Authors: Chaitali Parikh, Vasantharajan Janakiraman, Wen‐I Wu, Catherine K. Foo, Noelyn M. Kljavin, Subhra Chaudhuri, Eric Stawiski, Brian Lee, Jie Lin, Hong Li, Maria Lorenzo, Wenlin Yuan, Joseph Guillory, Marlena Jackson, Jesus Rondon, Yvonne Franke, Krista K. Bowman, Meredith Sagolla, Jeremy Stinson, Thomas D. Wu, Jiansheng Wu, David Stokoe, Howard M. Stern, Barbara J. Brandhuber, Kui Lin, Nicholas J. Skelton, Somasekar Seshagiri - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 150

  21. Sp1 Is Involved in Akt-mediated Induction of VEGF Expression through an HIF-1–independent Mechanism

    Authors: Nabendu Pore, Shuang Liu, Hui‐Kuo G. Shu, Bin Li, Daphne A. Haas-Kogan, David Stokoe, Julie Milanini, Gilles Pagès, Donald M. O’Rourke, Eric J. Bernhard, Amit Maity - Molecular Biology of the Cell 2004 cited by 227

  22. Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

    Authors: David Stokoe, Katrin Engel, David G. Campbell, Philip Cohen, Matthias Gaestel - FEBS Letters 1992 cited by 574

  23. High Frequency of Coexistent Mutations of PIK3CA and PTEN Genes in Endometrial Carcinoma

    Authors: Katsutoshi Oda, David Stokoe, Yuji Taketani, Frank McCormick - Cancer Research 2005 cited by 465

  24. Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

    Authors: Xiaolan Hu, Howard M. Stern, Lin Ge, Carol O’Brien, Lauren E. Haydu, Cynthia D. Honchell, Peter M. Haverty, Brock A. Peters, Thomas D. Wu, Lukas C. Amler, John Chant, David Stokoe, Mark R. Lackner, Guy Cavet - Molecular Cancer Research 2009 cited by 216