Graeme Alexander
Active 1982–2022
- 86
- Papers
- 22,792
- Citations
- 77
- h-index
- 86
- i10-index
Citations
Citation sources
Countries
Institutions
- University College London0.9%
- Inserm0.8%
- University of Cambridge0.7%
- Harvard University0.6%
- University of Birmingham0.5%
- Newcastle University0.5%
- Other96%
Fields
- Medicine71.4%
- Biochemistry, Genetics and Molecular Biology12.3%
- Immunology and Microbiology9%
- Pharmacology, Toxicology and Pharmaceutics4.6%
- Engineering0.9%
- Neuroscience0.4%
- Other1.4%
Topics
- Liver Disease Diagnosis and Treatment10%
- Hepatitis C virus research6.2%
- Liver Disease and Transplantation5.3%
- Liver Diseases and Immunity5.1%
- Hepatitis B Virus Studies4.4%
- Organ Transplantation Techniques and Outcomes3.1%
- Other65.9%
Coauthors
- Roger Williams18
- A L Eddleston9
- George Mells8
- James Neuberger8
- Richard Sandford8
- Bernard Portmann7
- Gideon M. Hirschfield7
- Michael A. Heneghan7
- Simon Rushbrook7
- Aileen Marshall6
- Andrew Bathgate6
- D. I. Jones6
- Matthew Cramp6
- Michael Allison6
- Douglas Thorburn5
- John G. O’Grady5
- Nick Sheron5
- Peter T. Donaldson5
- Salim I. Khakoo5
- Susan Davies5
- Aloysious Aravinthan4
- Anil Dhawan4
- Brian D. M. Tom4
- D. G. D. Wight4
All papers
- TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease
Authors: Yang‐Lin Liu, Helen L. Reeves, Alastair D. Burt, Dina Tiniakos, Stuart McPherson, Julian Leathart, Michael Allison, Graeme Alexander, A.-C. Piguet, Rodolphe Anty, Peter T. Donaldson, Guruprasad P. Aithal, Sven Francque, Luc Van Gaal, Karine Clément, Vlad Ratziu, Jean‐François Dufour, Christopher P. Day, Ann K. Daly, Quentin M. Anstee - Nature Communications 2014 cited by 617
- Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
Authors: Sun‐Gou Ji, The International PSC Study Group, Brian D. Juran, Sören Mucha, Trine Folseraas, Luke Jostins, Espen Melum, Natsuhiko Kumasaka, Elizabeth J. Atkinson, Erik M. Schlicht, Jimmy Z. Liu, Tejas Shah, Javier Gutierrez‐Achury, Kirsten Muri Boberg, Annika Bergquist, Séverine Vermeire, Bertus Eksteen, Peter R. Durie, Martti Färkkilâ, Tobias Müller, Christoph Schramm, Martina Sterneck, Tobias J. Weismüller, Daniel Gotthardt, David Ellinghaus, Felix Braun, Andreas Teufel, Mattias Laudes, Wolfgang Lieb, Gunnar Jacobs, Ulrich Beuers, Rinse K. Weersma, Cisca Wijmenga, Hanns–Ulrich Marschall, Piotr Milkiewicz, Albert Parés, Kimmo Kontula, Olivier Chazouillères, Pietro Invernizzi, Elizabeth C. Goode, Kelly Spiess, Carmel Moore, Jennifer Sambrook, Willem H. Ouwehand, David J. Roberts, John Danesh, Annarosa Floreani, Aliya Gulamhusein, John E. Eaton, Stefan Schreiber, Catalina Coltescu, Christopher L. Bowlus, Velimir A. Luketic, Joseph A. Odin, Kapil Chopra, Kris V. Kowdley, Naga Chalasani, Michael P. Manns, Brijesh Srivastava, George Mells, Richard Sandford, Graeme Alexander, Daniel J. Gaffney, Roger W. Chapman, Gideon M. Hirschfield, Mariza de Andrade, Simon Rushbrook, André Franke, Tom H. Karlsen, Konstantinos N. Lazaridis, Carl A. Anderson - Nature Genetics 2016 cited by 382
- Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
Authors: Fotios Sampaziotis, Alexander W. Justin, Olivia Tysoe, Stephen J. Sawiak, Edmund Godfrey, Sara Upponi, Richard L. Gieseck, Miguel Cardoso de Brito, Natalie Lie Berntsen, María J Gómez-Vázquez, Daniel Ortmann, Loukia Yiangou, Alexander Ross, Johannes Bargehr, Alessandro Bertero, Mariëlle C. F. Zonneveld, Marianne Terndrup Pedersen, Matthias Pawlowski, Laura Valestrand, Pedro Madrigal, Nikitas Georgakopoulos, Negar Pirmadjid, Gregor Skeldon, John Casey, Wenmiao Shu, Paulina M. Materek, Kirsten E Snijders, Stephanie Brown, Casey A. Rimland, Ingrid Simonic, Susan Davies, Kim B. Jensen, Matthias Zilbauer, William Gelson, Graeme Alexander, Sanjay Sinha, Nicholas R. F. Hannan, Thomas A. Wynn, Tom H. Karlsen, Espen Melum, Athina E. Markaki, Kourosh Saeb‐Parsy, Ludovic Vallier - Nature Medicine 2017 cited by 294
- British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis
Authors: Michael H. Chapman, Douglas Thorburn, Gideon M. Hirschfield, George Webster, Simon Rushbrook, Graeme Alexander, Jane Collier, Jessica Dyson, David Jones, Imran Patanwala, Collette Thain, Martine Walmsley, Stephen P. Pereira - Gut 2019 cited by 287
- Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease
Authors: Aloysious Aravinthan, Cinzia G. Scarpini, Phaedra Tachtatzis, Suman Verma, Sue Penrhyn-Lowe, Rebecca Harvey, Susan E. Davies, Michael Allison, Nick Coleman, Graeme Alexander - Journal of Hepatology 2012 cited by 313
- The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines
Authors: Gideon M. Hirschfield, Jessica Dyson, Graeme Alexander, Michael H. Chapman, Jane Collier, Stefan G. Hübscher, Imran Patanwala, Stephen P. Pereira, Collette Thain, Douglas Thorburn, Dina Tiniakos, Martine Walmsley, George Webster, D. I. Jones - Gut 2018 cited by 336
- Early indicators of prognosis in fulminant hepatic failure
Authors: John G. O'Grady, Graeme Alexander, Karen M. Hayllar, Roger Williams - Gastroenterology 1989 cited by 2,104
- The UK‐PBC risk scores: Derivation and validation of a scoring system for long‐term prediction of end‐stage liver disease in primary biliary cholangitis
Authors: Marco Carbone, Stephen J. Sharp, Steve Flack, Dimitrios Paximadas, Kelly Spiess, Carolyn Adgey, Laura Griffiths, R.T. Lim, Paul Trembling, Kate D. Williamson, Nick J. Wareham, Mark Aldersley, Andrew Bathgate, Andrew K. Burroughs, Michael A. Heneghan, James Neuberger, Douglas Thorburn, Gideon M. Hirschfield, Heather J. Cordell, Graeme Alexander, D. I. Jones, Richard Sandford, George Mells - Hepatology 2015 cited by 350
- Senescence in chronic liver disease: Is the future in aging?
Authors: Aloysious Aravinthan, Graeme Alexander - Journal of Hepatology 2016 cited by 165
- Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System
Authors: Elizabeth C. Goode, Allan Clark, George Mells, Brijesh Srivastava, Kelly Spiess, William Gelson, Palak Trivedi, Kate D. Lynch, Edit Castren, Mette Vesterhus, Tom H. Karlsen, Sun‐Gou Ji, Carl A. Anderson, Douglas Thorburn, Mark Hudson, Michael A. Heneghan, Mark Aldersley, Andrew Bathgate, Richard Sandford, Graeme Alexander, Roger W. Chapman, Martine Walmsley, Gideon M. Hirschfield, Simon Rushbrook - Hepatology 2018 cited by 103
- Role of Hepatocyte Senescence in the Activation of Hepatic Stellate Cells and Liver Fibrosis Progression
Authors: Pramudi Wijayasiri, Stuart Astbury, Philip Kaye, Fiona Oakley, Graeme Alexander, Timothy J. Kendall, Aloysious Aravinthan - Cells 2022 cited by 44
- Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
Authors: David L. Thomas, Chloe L. Thio, Maureen P. Martin, Qi Ying, Dongliang Ge, Colm Ó’hUigín, Judith R. Kidd, Kenneth K. Kídd, Salim I. Khakoo, Graeme Alexander, James J. Goedert, Gregory D. Kirk, Sharyne Donfield, Hugo R. Rosen, Leslie H. Tobler, Michael P. Busch, John G. McHutchison, David B. Goldstein, Mary Carrington - Nature 2009 cited by 2,160
- Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
Authors: Fotios Sampaziotis, Miguel Cardoso de Brito, Pedro Madrigal, Alessandro Bertero, Kourosh Saeb‐Parsy, Filipa Soares, E. Schrumpf, Espen Melum, Tom H. Karlsen, J. A. Bradley, William Gelson, Susan Davies, Alastair Baker, Arthur Kaser, Graeme Alexander, Nicholas R. F. Hannan, Ludovic Vallier - Nature Biotechnology 2015 cited by 395
- Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid
Authors: Marco Carbone, George Mells, Greta Pells, Muhammad F. Dawwas, Julia L. Newton, Michael A. Heneghan, James Neuberger, Darren B. Day, Samantha Ducker, Richard Sandford, Graeme Alexander, D. I. Jones - Gastroenterology 2012 cited by 384
- Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease
Authors: Aloysious Aravinthan, Giada Pietrosi, Matthew Hoare, James Jupp, Aileen Marshall, Clare Verrill, Susan Davies, Adrian C Bateman, Nick Sheron, Michael Allison, Graeme Alexander - PLoS ONE 2013 cited by 109
- Impact of primary biliary cirrhosis on perceived quality of life: The UK-PBC national study
Authors: George Mells, Greta Pells, Julia L. Newton, Andrew Bathgate, Andrew K. Burroughs, Michael A. Heneghan, James Neuberger, Darren B. Day, Samantha Ducker, Richard Sandford, Graeme Alexander, David Jones - Hepatology 2013 cited by 218
- HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection
Authors: Salim I. Khakoo, Chloe L. Thio, Maureen P. Martin, Collin Brooks, Xiaojiang Gao, Jacquie Astemborski, Jie Cheng, James J. Goedert, David Vlahov, Margaret W. Hilgartner, S.T. Cox, Ann-Margeret Little, Graeme Alexander, Matthew Cramp, Stephen J. O’Brien, William Rosenberg, David L. Thomas, Mary Carrington - Science 2004 cited by 1,190
- Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Authors: Jimmy Z. Liu, The International PSC Study Group, Johannes R. Hov, Trine Folseraas, Eva Ellinghaus, Simon Rushbrook, Nadezhda T. Doncheva, Ole A. Andreassen, Rinse K. Weersma, Tobias J. Weismüller, Bertus Eksteen, Pietro Invernizzi, Gideon M. Hirschfield, Daniel Gotthardt, Albert Parés, David Ellinghaus, Tejas Shah, Brian D. Juran, Piotr Milkiewicz, Christian Rust, Christoph Schramm, Tobias Müller, Brijesh Srivastava, Georgios Dalekos, Markus M. Nöthen, Stefan Herms, Juliane Winkelmann, Mitja Mitrovič, Felix Braun, Cyriel Y. Ponsioen, Peter J.P. Croucher, Martina Sterneck, Andreas Teufel, Andrew L. Mason, Janna Saarela, Virpi Leppä, Ruslan Dorfman, Domenico Alvaro, Annarosa Floreani, Suna Önengüt-Gümüşcü, Stephen S. Rich, Wesley K. Thompson, Andrew J. Schork, Sigrid Næss, Ingo Thomsen, Gabriele Mayr, Inke R. König, Kristian Hveem, Isabelle Cleynen, Javier Gutierrez‐Achury, Isis Ricaño-Ponce, David A. van Heel, Einar Björnsson, Richard Sandford, Peter R. Durie, Espen Melum, Morten H. Vatn, Mark S. Silverberg, Richard H. Duerr, Leonid Padyukov, Stephan Brand, Miquel Sans, Vito Annese, Jean–Paul Achkar, Kirsten Muri Boberg, Hanns–Ulrich Marschall, Olivier Chazouillères, Christopher L. Bowlus, Cisca Wijmenga, Erik Schrumpf, Séverine Vermeire, Mario Albrecht, John D. Rioux, Graeme Alexander, Annika Bergquist, Judy H. Cho, Stefan Schreiber, Michael P. Manns, Martti Färkkilâ, Anders M. Dale, Roger W. Chapman, Konstantinos N. Lazaridis, André Franke, Carl A. Anderson, Tom H. Karlsen - Nature Genetics 2013 cited by 398
- Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score
Authors: Marco Carbone, Alessandra Nardi, Steve Flack, Guido Carpino, Nikoletta Varvaropoulou, Caius Gavrila, Ann Spicer, Jonathan Badrock, Francesca Bernuzzi, Vincenzo Cardinale, Holly F. Ainsworth, Michael A. Heneghan, Douglas Thorburn, Andrew Bathgate, Rebecca Jones, James Neuberger, Pier Maria Battezzati, Massimo Zuin, Simon D. Taylor‐Robinson, Maria Francesca Donato, John A. Kirby, Robert Mitchell-Thain, Annarosa Floreani, Fotios Sampaziotis, Luigi Muratori, Domenico Alvaro, Marco Marzioni, Luca Miele, Fabio Marra, Edoardo G. Giannini, Eugenio Gaudio, Vincenzo Ronca, Giulia Bonato, Laura Cristoferi, Federica Malinverno, Alessio Gerussi, Deborah Stocken, Heather J. Cordell, Gideon M. Hirschfield, Graeme Alexander, Richard Sandford, David Jones, Pietro Invernizzi, George Mells, Caradog Thomas, Meshbah Rahman, Tom Yapp, Chin Lye Ch’ng, Melanie Harrison, Richard Sturgess, Roman Galaska, Chris Healey, Jessica Whiteman, Marek Czaijkowski, Catherine Gray, Anton Gunasekera, Pranab Gyawli, Purushothaman Premchand, Steven Mann, Keith Elliott, Kapil Kapur, Alan Watson, Graham R. Foster, Paul Trembling, Javaid Subhani, Rory Harvey, Roger McCorry, Carolyn Adgey, Lucie Hobson, Caroline Mulvaney-Jones, Richard J. Evans, Thiriloganathan Mathialahan, David Ramanaden, Jaber Gasem, Greta Van Duyvenvoorde, C Shorrock, Katie Seward, Paul Southern, Jeremy Tibble, Ruth Penn, David Gorard, Jane Maiden, Rose Damant, Altaf Palegwala, Susan Jones, Graeme Alexander, George Mells, Richard Sandford, Jessica Whiteman, Sunil Dolwani, Martin Prince, Valéria Damasceno Silvestre, Matthew Foxton, Eleanor Dungca, Harriet Mitchison, Natalie Wheatley, Ian Gooding, Helen Doyle, Mazn Karmo, Melanie Kent and 304 more - The Lancet. Gastroenterology & hepatology 2018 cited by 163
- Investigation and management of Wilson's disease: a practical guide from the British Association for the Study of the Liver
Authors: Samuel Shribman, Thomas Marjot, Abubakar Sharif, Sunitha Vimalesvaran, Aftab Ala, Graeme Alexander, Anil Dhawan, James Dooley, Godfrey T. Gillett, Déirdre Kelly, Alisdair McNeill, Thomas T. Warner, Valerie Wheater, William J. Griffiths, Oliver Bandmann - The Lancet. Gastroenterology & hepatology 2022 cited by 77
- Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease
Authors: Julie Parkes, Paul Roderick, Scott Harris, Christopher P. Day, David Mutimer, Jane Collier, M. Lombard, Graeme Alexander, John Ramage, Geoffrey Dusheiko, Mark Wheatley, Carol Gough, Alastair D. Burt, William Rosenberg - Gut 2010 cited by 345
- Ageing, telomeres, senescence, and liver injury
Authors: Matthew Hoare, Tapas Das, Graeme Alexander - Journal of Hepatology 2010 cited by 179
- Pruritus Is Common and Undertreated in Patients With Primary Biliary Cholangitis in the United Kingdom
Authors: Vinod S. Hegade, George Mells, Holly Fisher, Stuart Kendrick, Julia DiBello, Kim Gilchrist, Graeme Alexander, Gideon M. Hirschfield, Richard Sandford, D. I. Jones - Clinical Gastroenterology and Hepatology 2018 cited by 85
- Primary liver cancer in the UK: Incidence, incidence-based mortality, and survival by subtype, sex, and nation
Authors: Anya Burton, Daniela Tataru, R. Driver, Thomas G. Bird, Dyfed Huws, David Wallace, Timothy Cross, Ian Rowe, Graeme Alexander, Aileen Marshall, Anya Burton, Aileen Marshall, Graeme Alexander, Ian Rowe, Robert J. Driver, Vinay Kumar, Tim Cross, Katherine Cullen, Rhys Pockett, Tom Bird, Dyfed Huws, Anna Gavin, Daniela Tataru, Lizz Paley, David Wallace, Guruprasad P. Aithal - JHEP Reports 2021 cited by 69
