Howard A. Young
Active 1975–2024
- 148
- Papers
- 31,950
- Citations
- 107
- h-index
- 147
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine40.1%
- Immunology and Microbiology31.2%
- Biochemistry, Genetics and Molecular Biology21.6%
- Neuroscience3.4%
- Agricultural and Biological Sciences1.1%
- Engineering0.6%
- Other2%
Topics
- Immune Cell Function and Interaction7.7%
- T-cell and B-cell Immunology4.8%
- Immunotherapy and Immune Responses3.7%
- Immune Response and Inflammation3.3%
- Immune cells in cancer2.1%
- interferon and immune responses1.9%
- Other76.5%
Coauthors
- John R. Ortaldo18
- Tomoaki Hoshino9
- Deborah L. Hodge7
- Jay H. Bream7
- Lisa E. Hensley7
- Robin Winkler-Pickett7
- Antonio Sica6
- Joost J. Oppenheim6
- Paritosh Ghosh6
- Robert H. Wiltrout6
- Thomas W. Geisbert6
- Edward M. Scolnick5
- Giorgio Trinchieri5
- Jianping Ye5
- Julio C. Valencia5
- M. Eric Gershwin5
- Peter B. Jahrling5
- Scott K. Durum5
- Thomas Y. Shih5
- William J. Murphy5
- Dan L. Longo4
- Della Reynolds4
- Douglas R. Lowy4
- Fanching Lin4
All papers
- Cytokines: From Clinical Significance to Quantification
Authors: Chao Liu, Dewei Chu, Kourosh Kalantar‐Zadeh, Jacob George, Howard A. Young, Guozhen Liu - Advanced Science 2021 cited by 899
- Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions
Authors: Ashley V. Menk, Nicole E. Scharping, Rebecca S. Moreci, Xue Zeng, Cliff Guy, Sonia R. Salvatore, Heekyong Bae, Jianxin Xie, Howard A. Young, Stacy G. Wendell, Greg M. Delgoffe - Cell Reports 2018 cited by 493
- IFN-γ: A cytokine at the right time, is in the right place
Authors: J. D. Burke, Howard A. Young - Seminars in Immunology 2019 cited by 251
- CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease
Authors: Shunsuke Sakai, Keith D. Kauffman, Michelle A. Sallin, Arlene H. Sharpe, Howard A. Young, Vitaly V. Ganusov, Daniel L. Barber - PLoS Pathogens 2016 cited by 353
- Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study
Authors: Anish Thomas, Rasa Vilimas, Christopher Trindade, Rebecca Erwin-Cohen, Nitin Roper, Liqiang Xi, Venkatesh Krishnasamy, Elliot Levy, Andy Mammen, Samantha Nichols, Yuanbin Chen, Vamsidhar Velcheti, Fang Yin, Éva Szabó, Yves Pommier, Seth M. Steinberg, Jane B. Trepel, Mark Raffeld, Howard A. Young, Javed Khan, Stephen M. Hewitt, Jung-Min Lee - Journal of Thoracic Oncology 2019 cited by 181
- Interleukin-1 polymorphisms associated with increased risk of gastric cancer
Authors: Emad El‐Omar, Mary Carrington, Wong-Ho Chow, Kenneth E.L. McColl, Jay H. Bream, Howard A. Young, Jesús Herrera, Jolanta Lissowska, Chiu-Chin Yuan, N. Rothman, George Lanyon, Maureen P. Martin, J F Fraumeni, Charles S. Rabkin - Nature 2000 cited by 2,386
- In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression
Authors: Ogyi Park, Hua Wang, Honglei Weng, Lionel Feigenbaum, Hai Li, Shi Yin, Sung Hwan Ki, Seong Ho Yoo, Steven Dooley, Fu‐Sheng Wang, Howard A. Young, Bin Gao - Hepatology 2011 cited by 244
- Current prospects of type II interferon γ signaling and autoimmunity
Authors: Daniel S. Green, Howard A. Young, Julio C. Valencia - Journal of Biological Chemistry 2017 cited by 178
- Interleukin 2 plays a central role in Th2 differentiation
Authors: Javier Cote-Sierra, Gilles Foucras, Liying Guo, Lynda Chiodetti, Howard A. Young, Jane Hu‐Li, Jinfang Zhu, William E. Paul - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 407
- Interferon-γ links ultraviolet radiation to melanomagenesis in mice
Authors: M. Raza Zaidi, Sean Davis, Frances P. Noonan, Cari Graff‐Cherry, Teresa S. Hawley, Robert L. Walker, Lionel Feigenbaum, Elaine Fuchs, Lyudmila Lyakh, Howard A. Young, Thomas J. Hornyak, Heinz Arnheiter, Giorgio Trinchieri, Paul S. Meltzer, Edward C. De Fabo, Glenn Merlino - Nature 2011 cited by 295
- Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation
Authors: Patrick Hwu, Mark Du, Réjean Lapointe, My Do, Milton W. Taylor, Howard A. Young - The Journal of Immunology 2000 cited by 742
- Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression
Authors: Julie L. Heinecke, Lisa A. Ridnour, Robert Y.S. Cheng, Christopher Switzer, Michael M. Lizardo, Chand Khanna, Sharon A. Glynn, S. Perwez Hussain, Howard A. Young, Stefan Ambs, David A. Wink - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 177
- Clinical Use of Interferon‐γ
Authors: Catriona Miller, Stephen G. Maher, Howard A. Young - Annals of the New York Academy of Sciences 2009 cited by 299
- Redirecting Migration of T Cells to Chemokine Secreted from Tumors by Genetic Modification with CXCR2
Authors: Michael H. Kershaw, Gang Wang, Jennifer A. Westwood, Russell K. Pachynski, H. Lee Tiffany, Francesco M. Marincola, Ena Wang, Howard A. Young, Philip M. Murphy, Patrick Hwu - Human Gene Therapy 2002 cited by 290
- Protein delivery using engineered virus-like particles
Authors: Stanislaw J. Kaczmarczyk, Kalavathy Sitaraman, Howard A. Young, Stephen H. Hughes, Deb K. Chatterjee - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 222
- Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells
Authors: Fiamma Salerno, Sander Engels, Maartje van den Biggelaar, Floris P. J. van Alphen, Aurélie Guislain, Wanqi Zhao, Deborah L. Hodge, Sarah E. Bell, Jan Paul Medema, Marieke von Lindern, Martin Turner, Howard A. Young, Monika C. Wolkers - Nature Immunology 2018 cited by 149
- Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients
Authors: Kazusa Ishii, Marie Pouzolles, Christopher D. Chien, Rebecca Erwin-Cohen, M. Eric Kohler, Haiying Qin, Haiyan Lei, Skyler A. Kuhn, Amanda K. Ombrello, Alina Dulau‐Florea, Michael Eckhaus, Haneen Shalabi, Bonnie Yates, Daniel A. Lichtenstein, Valérie S. Zimmermann, Taisuke Kondo, Jack F. Shern, Howard A. Young, Naomi Taylor, Nirali N. Shah, Terry J. Fry - Journal of Clinical Investigation 2020 cited by 70
- CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.
Authors: Craig B. Thompson, Tullia Lindsten, J A Ledbetter, S L Kunkel, Howard A. Young, Stephen G. Emerson, Jeffrey M. Leiden, Carl H. June - National Academy of Sciences, Proceedings of the National Academy of Sciences 1989 cited by 659
- Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression
Authors: Tihong Shao, Patrick S.C. Leung, Weici Zhang, Koichi Tsuneyama, William M. Ridgway, Howard A. Young, Zongwen Shuai, Aftab A. Ansari, M. Eric Gershwin - Cellular and Molecular Immunology 2022 cited by 36
- The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis
Authors: Zachary Roberts, Nadège Goutagny, Pin‐Yu Perera, Hiroki Kato, Himanshu Kumar, Taro Kawai, Shizuo Akira, Ram Savan, David Van Echo, Katherine A. Fitzgerald, Howard A. Young, Lai‐Ming Ching, Stefanie N. Vogel - The Journal of Experimental Medicine 2007 cited by 167
- Chronic expression of interferon‐gamma leads to murine autoimmune cholangitis with a female predominance
Authors: Heekyong Bae, Patrick S.C. Leung, Koichi Tsuneyama, Julio C. Valencia, Deborah L. Hodge, Seohyun Kim, Tim Back, Megan Karwan, Anand S. Merchant, Nobuyuki Baba, Dechun Feng, Ogyi Park, Bin Gao, Guoxiang Yang, M. Eric Gershwin, Howard A. Young - Hepatology 2016 cited by 117
- Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages
Authors: Julio C. Valencia, Rebecca A. Erwin-Cohen, Paul E. Clavijo, Clint Allen, Michael E. Sanford, Chi-Ping Day, Megan M. Hess, Morgan Johnson, Jie Yin, John M. Fenimore, Ian A. Bettencourt, Koichi Tsuneyama, Maria E. Romero, Kimberly D. Klarmann, Peng Jiang, Heekyong R. Bae, Daniel W. McVicar, Glenn Merlino, Elijah F. Edmondson, Niroshana Anandasabapathy, Howard A. Young - Cancer Research 2021 cited by 30
- Mechanisms Underlying Coagulation Abnormalities in Ebola Hemorrhagic Fever: Overexpression of Tissue Factor in Primate Monocytes/Macrophages Is a Key Event
Authors: Thomas W. Geisbert, Howard A. Young, Peter B. Jahrling, Kelly J. Davis, Elliott Kagan, Lisa E. Hensley - The Journal of Infectious Diseases 2003 cited by 364
- Pathogenesis of Ebola Hemorrhagic Fever in Cynomolgus Macaques
Authors: Thomas W. Geisbert, Lisa E. Hensley, Thomas Larsen, Howard A. Young, Douglas S. Reed, Joan B. Geisbert, Dana Scott, Elliott Kagan, Peter B. Jahrling, Kelly J. Davis - American Journal Of Pathology 2003 cited by 572
