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Jane B. Trepel

Active 1986–2024

129
Papers
20,706
Citations
89
h-index
128
i10-index

Citations

Citations per year for Jane B. Trepel1948: 1 citations1987: 6 citations1988: 2 citations1989: 3 citations1990: 12 citations1991: 9 citations1992: 12 citations1993: 15 citations1994: 16 citations1995: 17 citations1996: 27 citations1997: 38 citations1998: 61 citations1999: 73 citations2000: 83 citations2001: 89 citations2002: 121 citations2003: 138 citations2004: 160 citations2005: 163 citations2006: 163 citations2007: 153 citations2008: 174 citations2009: 153 citations2010: 189 citations2011: 233 citations2012: 234 citations2013: 215 citations2014: 188 citations2015: 187 citations2016: 192 citations2017: 161 citations2018: 192 citations2019: 570 citations2020: 701 citations2021: 789 citations2022: 661 citations2023: 490 citations2024: 746 citations2025: 406 citations2026: 9 citations1949–1986: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,076 citing papers, 32.6% of this breakdownChina: 1,146 citing papers, 12.1% of this breakdownUnited Kingdom: 586 citing papers, 6.2% of this breakdownItaly: 486 citing papers, 5.1% of this breakdownGermany: 426 citing papers, 4.5% of this breakdownJapan: 342 citing papers, 3.6% of this breakdownCanada: 329 citing papers, 3.5% of this breakdownFrance: 290 citing papers, 3.1% of this breakdownIndia: 203 citing papers, 2.2% of this breakdownSpain: 200 citing papers, 2.1% of this breakdownSouth Korea: 199 citing papers, 2.1% of this breakdownAustralia: 175 citing papers, 1.9% of this breakdown
0%32.6%Other 21%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology54.8%
  • Medicine34.8%
  • Immunology and Microbiology4.3%
  • Neuroscience1.4%
  • Engineering0.9%
  • Chemistry0.7%
  • Other3.1%

Topics

  • Heat shock proteins research5.3%
  • Cancer, Hypoxia, and Metabolism3.9%
  • Histone Deacetylase Inhibitors Research3%
  • Epigenetics and DNA Methylation2.8%
  • Cancer Immunotherapy and Biomarkers1.9%
  • PARP inhibition in cancer therapy1.6%
  • Other81.5%

Coauthors

All papers

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  1. Targeting the dynamic HSP90 complex in cancer

    Authors: Jane B. Trepel, Mehdi Mollapour, Giuseppe Giaccone, Len Neckers - Nature reviews. Cancer 2010 cited by 1,528

  2. MGMT Status as a Clinical Biomarker in Glioblastoma

    Authors: Madison Butler, Lőrinc Sándor Pongor, Yuting Su, Liqiang Xi, Mark Raffeld, Martha Quezado, Jane B. Trepel, Kenneth Aldape, Yves Pommier, Jing Wu - Trends in cancer 2020 cited by 346

  3. Structural and functional complexity of HSP90 in cellular homeostasis and disease

    Authors: Gabriela Chiosis, Chander Singh Digwal, Jane B. Trepel, Len Neckers - Nature Reviews Molecular Cell Biology 2023 cited by 204

  4. Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

    Authors: Nitin Roper, Moises J. Velez, Alberto Chiappori, Yoo Sun Kim, Jun S. Wei, Sivasish Sindiri, Nobuyuki Takahashi, Deborah Mulford, Suresh Kumar, Kris Ylaya, Christopher Trindade, Irena Manukyan, Anna‐Leigh Brown, Jane B. Trepel, Jung-Min Lee, Stephen M. Hewitt, Javed Khan, Anish Thomas - Nature Communications 2021 cited by 163

  5. Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

    Authors: Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli, Kelli M. Wilson, Yang Zhang, Erin Beck, Linda Sciuto, Samantha Nichols, Brian Elenbaas, Janusz Puc, Heike Dahmen, Astrid Zimmermann, Jillian Varonin, Christopher W. Schultz, Se Hyun Kim, Hirity Shimellis, Parth Desai, Carleen Klumpp‐Thomas, Lu Chen, Jameson Travers, Crystal McKnight, Sam Michael, Zina Itkin, Sunmin Lee, Akira Yuno, Min-Jung Lee, Christophe E. Redon, Jessica D. Kindrick, Cody J. Peer, Jun S. Wei, Mirit I. Aladjem, William D. Figg, Seth M. Steinberg, Jane B. Trepel, Frank T. Zenke, Yves Pommier, Javed Khan, Craig J. Thomas - Cancer Cell 2021 cited by 177

  6. Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti–PD-(L)1 Therapy

    Authors: Matthew D. Hellmann, Pasi A. Jänne, Mateusz Opyrchal, Navid Hafez, Luis E. Raez, Dmitry I. Gabrilovich, Fang Wang, Jane B. Trepel, Min-Jung Lee, Akira Yuno, Sunmin Lee, Susan Brouwer, Serap Sankoh, Lei Wang, David Tamang, Emmett V. Schmidt, Michael L. Meyers, Suresh S. Ramalingam, Elaine Shum, Peter Ordentlich - Clinical Cancer Research 2020 cited by 124

  7. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

    Authors: Jennifer S. Isaacs, Yun Jin Jung, David R. Mole, Sunmin Lee, Carlos A. Torres‐Cabala, Yuen‐Li Chung, Maria J. Merino, Jane B. Trepel, Berton Zbar, Jorge R. Toro, Peter J. Ratcliffe, W. Marston Linehan, Len Neckers - Cancer Cell 2005 cited by 942

  8. An update on the status of HSP90 inhibitors in cancer clinical trials

    Authors: Shraddha Rastogi, Abhinav Joshi, Nahoko Sato, Sunmin Lee, Min-Jung Lee, Jane B. Trepel, Len Neckers - Cell Stress and Chaperones 2024 cited by 103

  9. Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study

    Authors: Jung‐Min Lee, Jayakumar R. Nair, Alexandra S. Zimmer, Stanley Lipkowitz, Christina M. Annunziata, Maria J. Merino, Elizabeth M. Swisher, Maria I. Harrell, Jane B. Trepel, Min-Jung Lee, Mohammadhadi Bagheri, Dana‐Adriana Botesteanu, Seth M. Steinberg, Lori M. Minasian, Irene Ekwede, Elise C. Kohn - The Lancet Oncology 2018 cited by 212

  10. Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study

    Authors: Anish Thomas, Rasa Vilimas, Christopher Trindade, Rebecca Erwin-Cohen, Nitin Roper, Liqiang Xi, Venkatesh Krishnasamy, Elliot Levy, Andy Mammen, Samantha Nichols, Yuanbin Chen, Vamsidhar Velcheti, Fang Yin, Éva Szabó, Yves Pommier, Seth M. Steinberg, Jane B. Trepel, Mark Raffeld, Howard A. Young, Javed Khan, Stephen M. Hewitt, Jung-Min Lee - Journal of Thoracic Oncology 2019 cited by 181

  11. Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

    Authors: Nobu Oshima, Ryo Ishida, Shun Kishimoto, Kristin Beebe, Jeffrey Brender, Kazutoshi Yamamoto, Daniel J. Urban, Ganesha Rai, Michelle S. Johnson, Gloria A. Benavides, Giuseppe L. Squadrito, Dan Crooks, Joseph W. Jackson, Abhinav Joshi, Bryan T. Mott, Jonathan H. Shrimp, Michael A. Moses, Min-Jung Lee, Akira Yuno, Tobie D. Lee, Xin Hu, Tamara L. Anderson, Donna F. Kusewitt, Helen H. Hathaway, Ajit Jadhav, Didier Picard, Jane B. Trepel, James B. Mitchell, Gordon M. Stott, William Moore, Anton Simeonov, Larry A. Sklar, Jeffrey P. Norenberg, W. Marston Linehan, David J. Maloney, Chi V. Dang, Alex G. Waterson, Matthew D. Hall, Victor Darley‐Usmar, Murali C. Krishna, Leonard Μ. Neckers - Cell Reports 2020 cited by 122

  12. E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor–Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group

    Authors: Roisín M. Connolly, Fengmin Zhao, Kathy D. Miller, Min-Jung Lee, Richard Piekarz, Karen L. Smith, Ursa Brown‐Glaberman, Jennifer S. Winn, Bryan A. Faller, Adedayo A. Onitilo, Mark E. Burkard, G. Thomas Budd, Ellis Levine, Melanie Royce, Peter A. Kaufman, Alexandra Thomas, Jane B. Trepel, Antonio C. Wolff, Joseph A. Sparano - Journal of Clinical Oncology 2021 cited by 119

  13. Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors

    Authors: Anish Thomas, Christophe E. Redon, Linda Sciuto, Emerson Padiernos, Jiuping Ji, Min-Jung Lee, Akira Yuno, Sunmin Lee, Yiping Zhang, Lan Tran, William H. Yutzy, Arun Rajan, Udayan Guha, Haobin Chen, Raffit Hassan, Christine Alewine, Éva Szabó, Susan E. Bates, Robert J. Kinders, Seth M. Steinberg, James H. Doroshow, Mirit I. Aladjem, Jane B. Trepel, Yves Pommier - Journal of Clinical Oncology 2017 cited by 174

  14. High‐fidelity detection and sorting of nanoscale vesicles in viral disease and cancer

    Authors: Aizea Morales‐Kastresana, Thomas Musich, Joshua A Welsh, William G. Telford, Thorsten Demberg, James C. S. Wood, Marty Bigos, Carley D. Ross, Aliaksander Kachynski, Alan Dean, Edward J. Felton, Jonathan Van Dyke, John Tigges, Vasilis Toxavidis, David R. Parks, W. Roy Overton, Aparna H. Kesarwala, Gordon J. Freeman, Ariel Rosner, Stephen P. Perfetto, Lise Pasquet, Masaki Terabe, Katherine McKinnon, Veena Kapoor, Jane B. Trepel, Anu Puri, Hisataka Kobayashi, Bryant C. Yung, Xiaoyuan Chen, Peter Guion, Peter L. Choyke, Susan J. Knox, Ionita Ghiran, Marjorie Robert‐Guroff, Jay A. Berzofsky, Jennifer Jones - Journal of Extracellular Vesicles 2019 cited by 130

  15. HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

    Authors: Toshiki Kijima, Thomas L. Prince, Megan L. Tigue, Kendrick Yim, Harvey Schwartz, Kristin Beebe, Sunmin Lee, Marek A. Budzyński, Heinric Williams, Jane B. Trepel, Lea Sistonen, Stuart K. Calderwood, Len Neckers - Scientific Reports 2018 cited by 148

  16. Phase I Study of Cabozantinib and Nivolumab Alone or With Ipilimumab for Advanced or Metastatic Urothelial Carcinoma and Other Genitourinary Tumors

    Authors: Andrea B. Apolo, Rosa Nadal, Daniel M. Girardi, Scot A. Niglio, Lisa Ley, Lisa M. Cordes, Seth M. Steinberg, Olena Sierra Ortiz, Jacqueline Cadena, Carlos Guerrero Díaz, Marissa Mallek, Nicole N. Davarpanah, Rene Costello, Jane B. Trepel, Min-Jung Lee, Maria J. Merino, Mohammadhadi Bagheri, Paul Monk, William D. Figg, James L. Gulley, Piyush K. Agarwal, Vladimir Valera, Heather J. Chalfin, Jennifer Jones, Howard Streicher, John J. Wright, Yang‐Min Ning, Howard L. Parnes, William L. Dahut, Donald P. Bottaro, Primo N. Lara, Biren Saraiya, Sumanta K. Pal, Mark N. Stein, Amir Mortazavi - Journal of Clinical Oncology 2020 cited by 137

  17. Update on Hsp90 Inhibitors in Clinical Trial

    Authors: Yoonhee Kim, S. Alarcon, S. Lee, M.-J. Lee, Giuseppe Giaccone, Len Neckers, Jane B. Trepel - Current Topics in Medicinal Chemistry 2009 cited by 307

  18. Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor

    Authors: Denise A. Yardley, Roohi Ismail‐Khan, Bohuslav Melichar, Mikhail Lichinitser, Pamela N. Münster, Pamela Klein, Scott Cruickshank, Kathy D. Miller, Min J. Lee, Jane B. Trepel - Journal of Clinical Oncology 2013 cited by 418

  19. Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations

    Authors: Fatima Karzai, David James VanderWeele, Ravi A. Madan, Helen Owens, Lisa M. Cordes, Amy Hankin, Anna Couvillon, E. Hitt Nichols, Marijo Bilušić, Michael L. Beshiri, Kathleen Kelly, Venkatesh Krishnasamy, Sunmin Lee, Min-Jung Lee, Akira Yuno, Jane B. Trepel, Maria J. Merino, Ryan Dittamore, Jennifer L. Marté, Renee N. Donahue, Jeffrey Schlom, Keith Killian, Paul S. Meltzer, Seth M. Steinberg, James L. Gulley, Jung Min Lee, William L. Dahut - Journal for ImmunoTherapy of Cancer 2018 cited by 312

  20. Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

    Authors: Soichiro Yoshida, Shinji Tsutsumi, Guillaume Mühlebach, Carole Sourbier, Min-Jung Lee, Sunmin Lee, Evangelia Vartholomaiou, Manabu Tatokoro, Kristin Beebe, Naoto Miyajima, Robert P. Mohney, Yang Chen, Hisashi Hasumi, Wanping Xu, Hiroshi Fukushima, Ken Nakamura, Fumitaka Koga, Kazunori Kihara, Jane B. Trepel, Didier Picard, Leonard Μ. Neckers - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 300

  21. Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity

    Authors: Mikako Ogawa, Yusuke Tomita, Yuko Nakamura, Min-Jung Lee, Sunmin Lee, Saori Tomita, Tadanobu Nagaya, Kazuhide Sato, Toyohiko Yamauchi, Hidenao Iwai, Abhishek Kumar, Timothy Haystead, Hari Shroff, Peter L. Choyke, Jane B. Trepel, Hisataka Kobayashi - Oncotarget 2017 cited by 259

  22. IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis

    Authors: Yunjin Jung, Jennifer S. Isaacs, Sunmin Lee, Jane B. Trepel, Len Neckers - The FASEB Journal 2003 cited by 675

  23. Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial

    Authors: Anish Thomas, Arun Rajan, Arlene Berman, Yusuke Tomita, Christina Brzezniak, Min-Jung Lee, Sunmin Lee, Alexander Ling, Aaron John Spittler, Corey A. Carter, Udayan Guha, Yisong Wang, Éva Szabó, Paul S. Meltzer, Seth M. Steinberg, Jane B. Trepel, Patrick J. Loehrer, Giuseppe Giaccone - The Lancet Oncology 2015 cited by 299

  24. The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels

    Authors: Wing‐Hang Tong, Carole Sourbier, Gennady Kovtunovych, Suh Young Jeong, Manish Vira, Manik C. Ghosh, Vladimir Valera Romero, Rachid Sougrat, Sophie Vaulont, Benoı̂t Viollet, Yeong-Sang Kim, Sunmin Lee, Jane B. Trepel, Ramaprasad Srinivasan, Gennady Bratslavsky, Youfeng Yang, W. Marston Linehan, Tracey A. Rouault - Cancer Cell 2011 cited by 214