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Peter J. Ratcliffe

Active 1984–2025

206
Papers
72,553
Citations
124
h-index
201
i10-index

Citations

Citations per year for Peter J. Ratcliffe1926: 1 citations1967: 1 citations1974: 1 citations1979: 1 citations1984: 2 citations1989: 29 citations1990: 9 citations1991: 10 citations1992: 25 citations1993: 32 citations1994: 33 citations1995: 50 citations1996: 98 citations1997: 138 citations1998: 214 citations1999: 279 citations2000: 427 citations2001: 581 citations2002: 822 citations2003: 1,180 citations2004: 1,246 citations2005: 1,127 citations2006: 1,088 citations2007: 997 citations2008: 955 citations2009: 1,154 citations2010: 978 citations2011: 942 citations2012: 858 citations2013: 961 citations2014: 851 citations2015: 836 citations2016: 864 citations2017: 789 citations2018: 644 citations2019: 1,933 citations2020: 2,270 citations2021: 2,042 citations2022: 1,532 citations2023: 1,033 citations2024: 1,587 citations2025: 657 citations2026: 16 citations1927–1966: no citations, so these years are not shown1968–1973: no citations, so these years are not shown1975–1978: no citations, so these years are not shown1980–1983: no citations, so these years are not shown1985–1988: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 6,244 citing papers, 28.4% of this breakdownChina: 2,600 citing papers, 11.8% of this breakdownUnited Kingdom: 2,007 citing papers, 9.1% of this breakdownGermany: 1,251 citing papers, 5.7% of this breakdownJapan: 852 citing papers, 3.9% of this breakdownItaly: 848 citing papers, 3.9% of this breakdownCanada: 718 citing papers, 3.3% of this breakdownFrance: 681 citing papers, 3.1% of this breakdownSwitzerland: 455 citing papers, 2.1% of this breakdownNetherlands: 432 citing papers, 2% of this breakdownAustralia: 430 citing papers, 1.9% of this breakdownSpain: 426 citing papers, 1.9% of this breakdown
0%28.4%Other 22.9%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology61%
  • Medicine27.9%
  • Immunology and Microbiology4%
  • Neuroscience1.6%
  • Engineering1.3%
  • Environmental Science0.9%
  • Other3.3%

Topics

  • Cancer, Hypoxia, and Metabolism14.2%
  • Epigenetics and DNA Methylation2.9%
  • Mitochondrial Function and Pathology2.7%
  • RNA modifications and cancer2.7%
  • Angiogenesis and VEGF in Cancer2.3%
  • High Altitude and Hypoxia2.2%
  • Other73%

Coauthors

All papers

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  1. Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

    Authors: William G. Kaelin, Peter J. Ratcliffe - Molecular Cell 2008 cited by 3,236

  2. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation

    Authors: Panu Jaakkola, David R. Mole, Ya‐Min Tian, Michael Wilson, Adriana Gielbert, Simon J. Gaskell, Alex von Kriegsheim, Holger Hebestreit, Mridul Mukherji, Christopher J. Schofield, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe - Science 2001 cited by 5,538

  3. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

    Authors: Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang, Steven C. Clifford, Emma C. Vaux, Matthew E. Cockman, Charles C. Wykoff, Christopher W. Pugh, Eamonn R. Maher, Peter J. Ratcliffe - Nature 1999 cited by 5,225

  4. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

    Authors: Andrew Epstein, Jonathan Gleadle, Luke A. McNeill, Kirsty S. Hewitson, John P. O’Rourke, David R. Mole, Mridul Mukherji, Eric Metzen, Michael Wilson, Anu Dhanda, Ya‐Min Tian, Norma Masson, Donald L. Hamilton, Panu Jaakkola, Robert Barstead, Jonathan Hodgkin, Patrick H. Maxwell, Christopher W. Pugh, Christopher J. Schofield, Peter J. Ratcliffe - Cell 2001 cited by 3,353

  5. Regulation of angiogenesis by hypoxia: role of the HIF system

    Authors: Christopher W. Pugh, Peter J. Ratcliffe - Nature Medicine 2003 cited by 2,511

  6. Oxygen sensing by HIF hydroxylases

    Authors: Christopher J. Schofield, Peter J. Ratcliffe - Nature Reviews Molecular Cell Biology 2004 cited by 2,036

  7. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

    Authors: Peter Carmeliet, Yuval Dor, Jean-Marc Herbert, Dai Fukumura, Koen Brusselmans, Mieke Dewerchin, Michal Neeman, Françoise Bono, Rinat Abramovitch, Patrick H. Maxwell, Cameron J. Koch, Peter J. Ratcliffe, Lieve Moons, Rakesh K. Jain, Désiré Collen, Eli Keshet - Nature 1998 cited by 2,505

  8. Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL

    Authors: Wai‐Ching Hon, Michael Wilson, Karl Harlos, Timothy D. W. Claridge, Christopher J. Schofield, Christopher W. Pugh, Patrick H. Maxwell, Peter J. Ratcliffe, David I. Stuart, E. Yvonne Jones - Nature 2002 cited by 753

  9. The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

    Authors: Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian, Lars Hillringhaus, Eleanor A. L. Bagg, Nathan R. Rose, Ivanhoe K. H. Leung, Xuan S Li, Esther C. Y. Woon, Ming Yang, M.A. McDonough, Oliver N. F. King, I.J. Clifton, Robert J. Klose, Timothy D. W. Claridge, Peter J. Ratcliffe, Christopher J. Schofield, Akane Kawamura - EMBO Reports 2011 cited by 1,031

  10. Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

    Authors: Julie Adam, Emine Hatipoglu, Linda O′Flaherty, Nicola Ternette, Natasha Sahgal, Helen Lockstone, Dilair Baban, Emma Nye, Gordon Stamp, Kathryn Wolhuter, Marcus Stevens, Román Fischer, Peter Carmeliet, Patrick H. Maxwell, Christopher W. Pugh, Norma Frizzell, Tomoyoshi Soga, Benedikt M. Kessler, Mona El‐Bahrawy, Peter J. Ratcliffe, Patrick J. Pollard - Cancer Cell 2011 cited by 578

  11. Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor

    Authors: Rebecca J. Appelhoff, Ya‐Min Tian, Raju R. Raval, Helen Turley, Adrian L. Harris, Christopher W. Pugh, Peter J. Ratcliffe, Jonathan Gleadle - Journal of Biological Chemistry 2004 cited by 1,106

  12. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.

    Authors: Heidi Sowter, Peter J. Ratcliffe, Peter H. Watson, Arnold H. Greenberg, Adrian L. Harris - 2001 cited by 717

  13. Mechanisms of hypoxia signalling: new implications for nephrology

    Authors: Johannes Schödel, Peter J. Ratcliffe - Nature Reviews Nephrology 2019 cited by 326

  14. Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

    Authors: Johannes Schödel, Steffen Grampp, Eamonn R. Maher, Holger Moch, Peter J. Ratcliffe, Paul Russo, David R. Mole - European Urology 2015 cited by 423

  15. Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

    Authors: Norma Masson, Thomas P. Keeley, Beatrice Giuntoli, Mark D. White, Mikel Lavilla-Puerta, Pierdomenico Perata, Richard J. Hopkinson, Emily Flashman, Francesco Licausi, Peter J. Ratcliffe - Science 2019 cited by 231

  16. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

    Authors: Jennifer S. Isaacs, Yun Jin Jung, David R. Mole, Sunmin Lee, Carlos A. Torres‐Cabala, Yuen‐Li Chung, Maria J. Merino, Jane B. Trepel, Berton Zbar, Jorge R. Toro, Peter J. Ratcliffe, W. Marston Linehan, Len Neckers - Cancer Cell 2005 cited by 942

  17. High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

    Authors: Johannes Schödel, Spyros Oikonomopoulos, Jiannis Ragoussis, Christopher W. Pugh, Peter J. Ratcliffe, David R. Mole - Blood 2011 cited by 734

  18. Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

    Authors: Ananda S. Mirchandani, Stephen J. Jenkins, Calum C. Bain, Manuel A. Sánchez-García, Hannah Lawson, Patrícia Coelho, Fiona Murphy, David Griffith, Ailiang Zhang, Tyler Morrison, Tony Ly, Simone Arienti, Pranvera Sadiku, Emily Watts, Rebecca Dickinson, Leila Reyes, George Cooper, Sarah A. Clark, David Lewis, Van Kelly, Christos Spanos, Kathryn Musgrave, Liam Delaney, I. Harper, Jonathan Scott, Nick Parkinson, Anthony Rostron, J. Kenneth Baillie, Sara Clohisey, Clare Pridans, Lara Campana, Philip Starkey Lewis, A. John Simpson, David H. Dockrell, Jürgen Schwarze, Nikhil Hirani, Peter J. Ratcliffe, Christopher W. Pugh, Kamil R. Kranc, Stuart J. Forbes, Moira K. B. Whyte, Sarah R. Walmsley - Nature Immunology 2022 cited by 80

  19. The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

    Authors: Katherine Louise Talks, Helen Turley, Kevin C. Gatter, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe, Adrian L. Harris - American Journal Of Pathology 2000 cited by 1,303

  20. Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

    Authors: Massimiliano Mazzone, Daniela Dettori, Rodrigo Leite de Oliveira, Sonja Loges, Thomas Schmidt, Bart Jonckx, Ya-Min Tian, Anthony A. Lanahan, Patrick J. Pollard, Carmen Ruiz de Almodóvar, Frederik De Smet, Stefan Vinckier, Julián Aragonés, Koen Debackere, Aernout Luttun, Sabine Wyns, Bénédicte F. Jordan, Alberto Pisacane, Bernard Gallez, Maria Grazia Lampugnani, Elisabetta Dejana, Michael Simons, Peter J. Ratcliffe, Patrick H. Maxwell, Peter Carmeliet - Cell 2009 cited by 816

  21. Widespread, hypoxia‐inducible expression of HIF‐2α in distinct cell populations of different organs

    Authors: Michael S. Wiesener, Jan Steffen Jürgensen, Christian Rosenberger, Charlotte Scholze, Jan Hörstrup, Christina Warnecke, Stefano J. Mandriota, Ingo Bechmann, Ulrich Frei, Christopher W. Pugh, Peter J. Ratcliffe, Sebastian Bachmann, Patrick H. Maxwell, Kai‐Uwe Eckardt - The FASEB Journal 2002 cited by 734

  22. Hypoxia-inducible expression of tumor-associated carbonic anhydrases.

    Authors: Charles C. Wykoff, Nigel Beasley, Peter H. Watson, Kevin Turner, Jaromı́r Pastorek, Amen Sibtain, George D. Wilson, Helen Turley, Kate Talks, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe, Adrian L. Harris - 2000 cited by 1,284

  23. Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

    Authors: David R. Mole, Christine Blancher, Richard R. Copley, Patrick J. Pollard, Jonathan Gleadle, Jiannis Ragoussis, Peter J. Ratcliffe - Journal of Biological Chemistry 2009 cited by 550

  24. Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

    Authors: Raju R. Raval, Kah Weng Lau, Maxine Tran, Heidi Sowter, Stefano J. Mandriota, Jiliang Li, Christopher W. Pugh, Patrick H. Maxwell, Adrian L. Harris, Peter J. Ratcliffe - Molecular and Cellular Biology 2005 cited by 933