James M. Downey
Active 1973–2023
- 95
- Papers
- 20,152
- Citations
- 84
- h-index
- 95
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine68.5%
- Biochemistry, Genetics and Molecular Biology23.9%
- Neuroscience2%
- Engineering1.4%
- Immunology and Microbiology1.1%
- Nursing1%
- Other2.1%
Topics
- Cardiac Ischemia and Reperfusion16.8%
- Cardiac Arrest and Resuscitation6.1%
- Anesthesia and Neurotoxicity Research3.8%
- Mitochondrial Function and Pathology3.7%
- Cardiac electrophysiology and arrhythmias2.7%
- Cardiovascular Function and Risk Factors2.5%
- Other64.4%
Coauthors
- Michael V. Cohen54
- Xi‐Ming Yang14
- Christopher Baines10
- Derek M. Yellon9
- J D Thornton9
- Guang S. Liu8
- Stuart D. Critz8
- G. S. Liu7
- Gerd Heusch7
- Sean M. Davidson7
- Edward S. Kirk6
- Hans Erik Bøtker5
- Kirsti Ytrehus5
- Michel Ovize5
- Sebastian Philipp5
- Thomas Krieg5
- Yongge Liu5
- Atsushi Nakano4
- Christof Weinbrenner4
- Derek J. Hausenloy4
- Lin Cui4
- Péter Ferdinandy4
- Qining Qin4
- Ye Liu4
All papers
- Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection
Authors: Gerd Heusch, Ioanna Andreadou, Robert M. Bell, Edoardo Bertero, Hans Erik Bøtker, Sean M. Davidson, James M. Downey, Philip Eaton, Péter Ferdinandy, Bernard J. Gersh, Mauro Giacca, Derek J. Hausenloy, Borja Ibáñez, Thomas Krieg, Christoph Maack, Rainer Schulz, Frank W. Sellke, Ajay M. Shah, Hölger Thiele, Derek M. Yellon, Fabio Di Lisa - Redox Biology 2023 cited by 135
- Guidelines for evaluating myocardial cell death
Authors: Paras K. Mishra, Adriana Adameová, Joseph A. Hill, Christopher Baines, Peter M. Kang, James M. Downey, Jagat Narula, Masafumi Takahashi, Antonio Abbate, Hande C. Piristine, Sumit Kar, Shi Su, Jason K. Higa, Nicholas K. Kawasaki, Takashi Matsui - American Journal of Physiology-Heart and Circulatory Physiology 2019 cited by 230
- Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function
Authors: Jonathon P. Audia, Xi‐Ming Yang, Edward S. Crockett, Nicole A. Housley, Ehtesham Ul Haq, Kristen O’Donnell, Michael V. Cohen, James M. Downey, Diego F. Alvarez - Basic Research in Cardiology 2018 cited by 178
- Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart
Authors: Derek J. Hausenloy, David García‐Dorado, Hans Erik Bøtker, Sean M. Davidson, James M. Downey, Felix B. Engel, Robert B. Jennings, Sandrine Lecour, Jonathan Leor, Rosalinda Madonna, Michel Ovize, Cinzia Perrino, Fabrice Prunier, Rainer Schulz, Joost P. G. Sluijter, Linda W. van Laake, Jakob Vinten-Johansen, Derek M. Yellon, Kirsti Ytrehus, G. Heusch, Péter Ferdinandy - Cardiovascular Research 2017 cited by 340
- Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery
Authors: Derek J. Hausenloy, José A. Barrabés, Hans Erik Bøtker, Sean M. Davidson, Fabio Di Lisa, James M. Downey, Thomas Engstrøm, Péter Ferdinandy, Hector A. Carbrera-Fuentes, G. Heusch, Borja Ibáñez, Efstathios K. Iliodromitis, J INSERTE, Robert B. Jennings, Neena Kalia, Rajesh Kharbanda, Sandrine Lecour, Michael Marber, Tetsuji Miura, Michel Ovize, Miguel A. Pérez‐Pinzón, Hans Michael Piper, Karin Przyklenk, Michael R. Schmidt, Andrew N. Redington, Marisol Ruiz‐Meana, Gemma Vilahur, Jakob Vinten‐Johansen, Derek M. Yellon, David García‐Dorado - Basic Research in Cardiology 2016 cited by 307
- Innate immunity as a target for acute cardioprotection
Authors: Coert J. Zuurbier, Antonio Abbate, Héctor A. Cabrera-Fuentes, Michael V. Cohen, Massimo Collino, Dominique P.V. de Kleijn, James M. Downey, Pasquale Pagliaro, Klaus T. Preissner, Masafumi Takahashi, Sean M. Davidson - Cardiovascular Research 2018 cited by 147
- Reactive Oxygen Species as Intracellular Signaling Molecules in the Cardiovascular System
Authors: А. В. Крылатов, Л. Н. Маслов, Nikita S. Voronkov, A Boshchenko, С. В. Попов, Ludovic Gomez, Hongxin Wang, Amteshwar Singh Jaggi, James M. Downey - Current Cardiology Reviews 2018 cited by 140
- Circulating blood cells and extracellular vesicles in acute cardioprotection
Authors: Sean M. Davidson, Ioanna Andreadou, Lucio Barile, Yochai Birnbaum, Héctor A. Cabrera-Fuentes, Michael V. Cohen, James M. Downey, Henrique Girão, Pasquale Pagliaro, Cláudia Penna, John Pernow, Klaus T. Preissner, Péter Ferdinandy - Cardiovascular Research 2018 cited by 137
- Detection of Airborne Severe Acute Respiratory Syndrome (SARS) Coronavirus and Environmental Contamination in SARS Outbreak Units
Authors: Timothy F. Booth, Bill Kournikakis, Nathalie Bastien, Jim Ho, Darwyn Kobasa, L L Stadnyk, Yan Li, Mel Spence, Shirley Paton, Bonnie Henry, Barbara Mederski, Diane White, Donald E. Low, Allison McGeer, Andrew E. Simor, Mary Vearncombe, James M. Downey, Frances Jamieson, Patrick Tang, Frank Plummer - The Journal of Infectious Diseases 2005 cited by 449
- The Role of Pyroptosis in Ischemic and Reperfusion Injury of the Heart
Authors: С. В. Попов, Л. Н. Маслов, N. V. Naryzhnaya, Alexandr V. Mukhomezyanov, А. В. Крылатов, S. Yu. Tsibulnikov, V. V. Ryabov, Michael V. Cohen, James M. Downey - Journal of Cardiovascular Pharmacology and Therapeutics 2021 cited by 47
- Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology
Authors: Derek M. Yellon, James M. Downey - Physiological Reviews 2003 cited by 1,058
- New and revisited approaches to preserving the reperfused myocardium
Authors: Robert A. Kloner, David A. Brown, Marie Csete, Wangde Dai, James M. Downey, Roberta A. Gottlieb, Sharon L. Hale, Jianru Shi - Nature Reviews Cardiology 2017 cited by 87
- 9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotection
Authors: Robert M. Bell, Hans Erik Bøtker, Richard D. Carr, Sean M. Davidson, James M. Downey, David P. Dutka, Gerd Heusch, Borja Ibáñez, Raymond J. MacAllister, Christian Stoppe, Michel Ovize, Andrew N. Redington, John M. Walker, Derek M. Yellon - Basic Research in Cardiology 2016 cited by 89
- Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.
Authors: G. S. Liu, J D Thornton, Donna M. Van Winkle, A Stanley, R A Olsson, James M. Downey - Circulation 1991 cited by 1,346
- The pH Hypothesis of Postconditioning
Authors: Michael V. Cohen, Xi‐Ming Yang, James M. Downey - Circulation 2007 cited by 290
- Platelet P2Y 12 Blockers Confer Direct Postconditioning-Like Protection in Reperfused Rabbit Hearts
Authors: Xi‐Ming Yang, Yan Liu, Lin Cui, Xiulan Yang, Yongge Liu, Narendra N. Tandon, Junichi Kambayashi, James M. Downey, Michael V. Cohen - Journal of Cardiovascular Pharmacology and Therapeutics 2012 cited by 144
- Signalling pathways and mechanisms of protection in pre‐ and postconditioning: historical perspective and lessons for the future
Authors: Michael V. Cohen, James M. Downey - British Journal of Pharmacology 2014 cited by 106
- Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways
Authors: Xi‐Ming Yang, Jennifer Proctor, Lin Cui, Thomas Krieg, James M. Downey, Michael V. Cohen - Journal of the American College of Cardiology 2004 cited by 490
- Ischemic Preconditioning: From Adenosine Receptor to KATP Channel
Authors: Michael V. Cohen, Christopher Baines, James M. Downey - Annual Review of Physiology 2000 cited by 469
- Free Radicals and Their Involvement During Long-Term Myocardial Ischemia and Reperfusion
Authors: James M. Downey - Annual Review of Physiology 1990 cited by 261
- Adenosine: trigger and mediator of cardioprotection
Authors: Michael V. Cohen, James M. Downey - Basic Research in Cardiology 2007 cited by 222
- New Horizons in Cardioprotection
Authors: Lisa Schwartz Longacre, Robert A. Kloner, Andrew E. Arai, Christopher Baines, Roberto Bolli, Eugene Braunwald, James M. Downey, Raymond J. Gibbons, Roberta A. Gottlieb, Gerd Heusch, Robert B. Jennings, David J. Lefer, Robert M. Mentzer, Elizabeth Murphy, Michel Ovize, Peipei Ping, Karin Przyklenk, Michael N. Sack, Richard S. Vander Heide, Jakob Vinten‐Johansen, Derek M. Yellon - Circulation 2011 cited by 215
- Myocardial protection with mild hypothermia
Authors: Renaud Tissier, Bijan Ghaleh, M. V. Cohen, James M. Downey, A. Berdeaux - Cardiovascular Research 2011 cited by 78
- Dissemination of Verona Integron-encoded Metallo-β-lactamase among clinical and environmental Enterobacteriaceae isolates in Ontario, Canada
Authors: Philipp Köhler, Nathalie Tijet, Hyunjin Cindy Kim, Jennie Johnstone, Tom Edge, Samir N. Patel, Christine Seah, Barbara Willey, Brenda L. Coleman, Karen Green, Irene Armstrong, Kevin Katz, Matthew Muller, Jeff Powis, Susan M. Poutanen, David Richardson, Alicia Sarabia, Andrew E. Simor, Allison McGeer, Roberto G. Melano, The Toronto Invasive Bacterial Diseases Network (TIBDN), Agron Plevneshi, Wallis Rudnick, Frances Jamieson, Barbara Yaffe, Larissa Matukas, James M. Downey, Wayne L. Gold, Sharon Walmsley, Mahin Baqi, Mary Vearncombe, Abdelbaset Belhaj, Ian Kitai, Danny Z. Chen, Eileen de Villa, Hani L. N. Dick, Nataly Farshait, K. Lee, Sigmund Krajden, Michael Lingley, Reena Lovinsky, David Rose, Sharon O’Grady, Anne Opavsky, Krystyna Ostrowska, Astrid Petrich, Susan E. Richardson, Neil Rau, Daniel Ricciuto, Valérie Sales, Deborah Yamamura - Scientific Reports 2020 cited by 28
