John J. Mekalanos
Active 1968–2024
- 197
- Papers
- 51,949
- Citations
- 129
- h-index
- 196
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology61.2%
- Immunology and Microbiology9.9%
- Medicine9.6%
- Environmental Science7.6%
- Agricultural and Biological Sciences7.3%
- Nursing0.8%
- Other3.6%
Topics
- Vibrio bacteria research studies11.9%
- Bacterial Genetics and Biotechnology7%
- Bacteriophages and microbial interactions5.5%
- Bacterial biofilms and quorum sensing5.4%
- Antibiotic Resistance in Bacteria5.2%
- Escherichia coli research studies5.1%
- Other59.9%
Coauthors
- Shah M. Faruque23
- Matthew K. Waldor15
- Stephen B. Calderwood12
- Michelle Dziejman10
- William P. Robins9
- G. Balakrish Nair8
- Brian T. Ho7
- James M. Slauch7
- Jun Zhu7
- Michael J. Mahan7
- Olga Danilchanka7
- Stefan Pukatzki7
- Tao Dong7
- Aaron T. Whiteley6
- David A. Sack6
- Eric J. Rubin6
- Marek Basler6
- Marian R. Neutra6
- R. John Collier6
- Virginia L. Miller6
- Andrew Camilli5
- Brian J. Akerley5
- David T. Beattie5
- John F. Heidelberg5
All papers
- Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
Authors: Wen Zhou, Aaron T. Whiteley, Carina C. de Oliveira Mann, Benjamin R. Morehouse, Radosław P. Nowak, Eric S. Fischer, Nathanael S. Gray, John J. Mekalanos, Philip J. Kranzusch - Cell 2018 cited by 406
- Bacterial cGAS-like enzymes synthesize diverse nucleotide signals
Authors: Aaron T. Whiteley, James B. Eaglesham, Carina C. de Oliveira Mann, Benjamin R. Morehouse, B. Lowey, Eric A. Nieminen, Olga Danilchanka, David S. King, Amy S. Y. Lee, John J. Mekalanos, Philip J. Kranzusch - Nature 2019 cited by 383
- Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system
Authors: Stefan Pukatzki, Amy T., Derek Sturtevant, Bryan Krastins, David Sarracino, William Nelson, John F. Heidelberg, John J. Mekalanos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 1,137
- A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein Secretion Apparatus
Authors: Joseph D. Mougous, M.E. Cuff, Stefan Raunser, Aimee Shen, Min Zhou, Casey A. Gifford, Andrew L. Goodman, G. Joachimiak, Claudia L. Ordoñez, Stephen Lory, Thomas Walz, A. Joachimiak, John J. Mekalanos - Science 2006 cited by 1,114
- A View to a Kill: The Bacterial Type VI Secretion System
Authors: Brian T. Ho, Tao Dong, John J. Mekalanos - Cell Host & Microbe 2013 cited by 648
- CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection
Authors: B. Lowey, Aaron T. Whiteley, Alexander F. A. Keszei, Benjamin R. Morehouse, Ian T. Mathews, Sadie P. Antine, V. Cabrera, Dmitry Kashin, Percy Niemann, Mohit Jain, Frank Schwede, John J. Mekalanos, Sichen Shao, Amy S.Y. Lee, Philip J. Kranzusch - Cell 2020 cited by 257
- PAAR-repeat proteins sharpen and diversify the type VI secretion system spike
Authors: Mikhail M. Shneider, S.A. Buth, Brian T. Ho, Marek Basler, John J. Mekalanos, P.G. Leiman - Nature 2013 cited by 546
- Lysogenic Conversion by a Filamentous Phage Encoding Cholera Toxin
Authors: Matthew K. Waldor, John J. Mekalanos - Science 1996 cited by 1,906
- Type VI secretion requires a dynamic contractile phage tail-like structure
Authors: Marek Basler, Martin Pilhofer, Gregory P. Henderson, Grant J. Jensen, John J. Mekalanos - Nature 2012 cited by 703
- Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin
Authors: Stefan Pukatzki, Amy T., Andrew T. Revel, Derek Sturtevant, John J. Mekalanos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 750
- Tit-for-Tat: Type VI Secretion System Counterattack during Bacterial Cell-Cell Interactions
Authors: Marek Basler, Brian T. Ho, John J. Mekalanos - Cell 2013 cited by 582
- Coordinated Regulation of Accessory Genetic Elements Produces Cyclic Di-Nucleotides for V. cholerae Virulence
Authors: Bryan W. Davies, Ryan W. Bogard, Travis S. Young, John J. Mekalanos - Cell 2012 cited by 456
- Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity
Authors: Rebecca Lau, Qiaozhen Ye, Erica A. Birkholz, Kyle R. Berg, Lucas Patel, Ian T. Mathews, Jeramie D. Watrous, Kaori M. Ego, Aaron T. Whiteley, B. Lowey, John J. Mekalanos, Philip J. Kranzusch, Mohit Jain, Joe Pogliano, Kevin D. Corbett - Molecular Cell 2020 cited by 213
- Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin
Authors: P.G. Leiman, Marek Basler, U.A. Ramagopal, J.B. Bonanno, J.M. Sauder, Stefan Pukatzki, S.K. Burley, Steven C. Almo, John J. Mekalanos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 642
- Cyclic Dinucleotides and the Innate Immune Response
Authors: Olga Danilchanka, John J. Mekalanos - Cell 2013 cited by 228
- Microbiota-targeted maternal antibodies protect neonates from enteric infection
Authors: Wenfeng Zheng, Wenjing Zhao, Meng Wu, Xinyang Song, Florence Caro, Ximei Sun, Francesca S. Gazzaniga, Giuseppe Stefanetti, Sungwhan F. Oh, John J. Mekalanos, Dennis L. Kasper - Nature 2020 cited by 155
- Gut complement induced by the microbiota combats pathogens and spares commensals
Authors: Meng Wu, Wenfeng Zheng, Xinyang Song, Bin Bao, Yuanyou Wang, Deepshika Ramanan, Daping Yang, Rui Liu, John C. Macbeth, A. Elyza, Warrison A. Andrade, Tiandi Yang, Hyoung‐Soo Cho, Francesca S. Gazzaniga, Marit Ilves, Daniela R. Coronado, Charlotte Thompson, Saiyu Hang, Isaac M. Chiu, Jeffrey R. Moffitt, Ansel Hsiao, John J. Mekalanos, Christophe Benoıst, Dennis L. Kasper - Cell 2024 cited by 85
- Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae
Authors: Tao Dong, Brian T. Ho, Deborah R. Yoder-Himes, John J. Mekalanos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 312
- DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
Authors: John F. Heidelberg, Jonathan A. Eisen, William Nelson, Rebecca A. Clayton, Michelle Gwinn, Robert J. Dodson, Daniel H. Haft, Erin K. Hickey, Jeremy Peterson, Lowell Umayam, Steven R. Gill, Karen E. Nelson, Timothy D. Read, Hervé Tettelin, Delwood Richardson, Maria D. Ermolaeva, Jessica Vamathevan, Steven Bass, Haiying Qin, Ioana Dragoi, Patrick Sellers, Lisa McDonald, Teresa R. Utterback, Robert D. Fleishmann, William C. Nierman, Owen White, Steven L. Salzberg, Hamilton O. Smith, Rita R. Colwell, John J. Mekalanos, J. Craig Venter, Claire M. Fraser - Nature 2000 cited by 1,904
- Antagonism toward the intestinal microbiota and its effect on Vibrio cholerae virulence
Authors: Wenjing Zhao, Florence Caro, William P. Robins, John J. Mekalanos - Science 2018 cited by 196
- SEDS proteins are a widespread family of bacterial cell wall polymerases
Authors: Alexander J. Meeske, Eammon P. Riley, William P. Robins, Tsuyoshi Uehara, John J. Mekalanos, Daniel Kahne, Suzanne Walker, Andrew C. Kruse, Thomas G. Bernhardt, David Z. Rudner - Nature 2016 cited by 531
- Epidemiology, Genetics, and Ecology of Toxigenic Vibrio cholerae
Authors: Shah M. Faruque, M. John Albert, John J. Mekalanos - Microbiology and Molecular Biology Reviews 1998 cited by 936
- Exopolysaccharide protects Vibrio cholerae from exogenous attacks by the type 6 secretion system
Authors: Jonida Toska, Brian T. Ho, John J. Mekalanos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 132
- Proteomic analysis of Vibrio cholerae outer membrane vesicles
Authors: Emrah Altındiş, Yang Fu, John J. Mekalanos - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 167
