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John M. Asara

Active 1999–2025

231
Papers
58,355
Citations
116
h-index
221
i10-index

Citations

Citations per year for John M. Asara1989: 1 citations1991: 1 citations1993: 1 citations1999: 2 citations2000: 3 citations2001: 38 citations2002: 127 citations2003: 151 citations2004: 158 citations2005: 170 citations2006: 163 citations2007: 162 citations2008: 167 citations2009: 196 citations2010: 205 citations2011: 357 citations2012: 510 citations2013: 613 citations2014: 787 citations2015: 917 citations2016: 1,025 citations2017: 1,189 citations2018: 1,164 citations2019: 2,919 citations2020: 3,438 citations2021: 3,424 citations2022: 2,774 citations2023: 2,220 citations2024: 3,127 citations2025: 1,606 citations2026: 47 citations1990: no citations, so this year is not shown1992: no citations, so this year is not shown1994–1998: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 9,417 citing papers, 29.2% of this breakdownChina: 6,079 citing papers, 18.8% of this breakdownUnited Kingdom: 1,813 citing papers, 5.6% of this breakdownGermany: 1,496 citing papers, 4.6% of this breakdownItaly: 1,079 citing papers, 3.3% of this breakdownJapan: 967 citing papers, 3% of this breakdownCanada: 950 citing papers, 3% of this breakdownFrance: 917 citing papers, 2.8% of this breakdownAustralia: 688 citing papers, 2.1% of this breakdownSpain: 663 citing papers, 2.1% of this breakdownSouth Korea: 663 citing papers, 2.1% of this breakdownSwitzerland: 575 citing papers, 1.8% of this breakdown
0%29.2%Other 21.6%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology57.5%
  • Medicine30.5%
  • Immunology and Microbiology4.5%
  • Neuroscience2.2%
  • Chemistry1%
  • Nursing1%
  • Other3.3%

Topics

  • Cancer, Hypoxia, and Metabolism8.7%
  • Autophagy in Disease and Therapy3.6%
  • Epigenetics and DNA Methylation3.4%
  • Metabolism, Diabetes, and Cancer2.7%
  • Mitochondrial Function and Pathology2.7%
  • RNA modifications and cancer2.5%
  • Other76.4%

Coauthors

All papers

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  1. Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

    Authors: Haoqiang Ying, Alec C. Kimmelman, Costas A. Lyssiotis, Sujun Hua, Gerald C. Chu, Eliot Fletcher-Sananikone, Jason W. Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L. Coloff, Haiyan Yan, Wei Wang, Shujuan Chen, Andrea Viale, Hongwu Zheng, Ji-Hye Paik, Carol S. Lim, Alexander R. Guimarães, Eric S. Martin, Jeffery Chang, Aram F. Hezel, Samuel R. Perry, Jian Hu, Boyi Gan, Yonghong Xiao, John M. Asara, Ralph Weissleder, Yanru Wang, Lynda Chin, Lewis C. Cantley, Ronald A. DePinho - Cell 2012 cited by 2,083

  2. Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

    Authors: Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova, Sara Gelino, Rebecca A. Kohnz, William B. Mair, Debbie S. Vasquez, Aashish Joshi, Dana M. Gwinn, Rebecca C. Taylor, John M. Asara, James A. J. Fitzpatrick, Andrew Dillin, Benoı̂t Viollet, Mondira Kundu, Malene Hansen, Reuben J. Shaw - Science 2010 cited by 2,599

  3. HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

    Authors: Mircea Ivan, Keiichi Kondo, Haifeng Yang, William Kim, Jennifer Valiando, Michael Ohh, Adrian Salic, John M. Asara, William S. Lane, William G. Kaelin - Science 2001 cited by 4,724

  4. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

    Authors: Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M. Perera, Cristina R. Ferrone, Edouard Mullarky, Ng Shyh‐Chang, Ya’an Kang, Jason B. Fleming, Nabeel Bardeesy, John M. Asara, Marcia C. Haigis, Ronald A. DePinho, Lewis C. Cantley, Alec C. Kimmelman - Nature 2013 cited by 2,007

  5. An inhibitor of oxidative phosphorylation exploits cancer vulnerability

    Authors: Jennifer R. Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Christopher A. Bristow, Timothy McAfoos, Pietro Morlacchi, Jeffrey J. Ackroyd, Ahmed-Noor A. Agip, Gheath Alatrash, John M. Asara, Jennifer Bardenhagen, Caroline C. Carrillo, Christopher L. Carroll, Edward Chang, Stefan O. Ciurea, Jason B. Cross, Barbara Czakó, Angela K. Deem, Naval Daver, John Frederick De Groot, Jian-Wen Dong, Ningping Feng, Guang Gao, Jason Gay, Mary Geck, Jennifer Greer, Virginia Giuliani, Jing Han, Lina Han, Verlene Henry, Judy Hirst, Sha Huang, Yongying Jiang, Zhijun Kang, Tin Oo Khor, Sergej Konoplev, Yu-Hsi Lin, Gang Liu, Alessia Lodi, Timothy Lofton, Helen Ma, Mikhila Mahendra, Polina Matre, Robert A. Mullinax, Michael Peoples, Alessia Petrocchi, Jaime Rodriguez-Canale, Riccardo Serreli, Thomas Shi, Melinda Smith, Yoko Tabe, Jay Theroff, Stefano Tiziani, Quanyun A. Xu, Qi Zhang, Florian L. Müller, Ronald A. DePinho, Carlo Toniatti, Giulio Draetta, Timothy P. Heffernan, Marina Konopleva, Philip Jones, Maria Emilia Di Francesco, Joseph R. Marszalek - Nature Medicine 2018 cited by 951

  6. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

    Authors: Valerie S. LeBleu, Joyce T. O’Connell, Karina N. Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C. Haigis, Fernanda Machado de Carvalho, Aline Santos Damascena, Ludmilla Thomé Domingos Chinen, Rafael Malagoli Rocha, John M. Asara, Raghu Kalluri - Nature Cell Biology 2014 cited by 1,416

  7. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

    Authors: Cristovão M. Sousa, Douglas E. Biancur, Xiaoxu Wang, Christopher J. Halbrook, Mara H. Sherman, Li Zhang, Daniel M. Kremer, Rosa F. Hwang, Agnes K. Witkiewicz, Haoqiang Ying, John M. Asara, Ronald M. Evans, Lewis C. Cantley, Costas A. Lyssiotis, Alec C. Kimmelman - Nature 2016 cited by 1,124

  8. Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

    Authors: Andrea Viale, Piergiorgio Pettazzoni, Costas A. Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani, Maria Kost‐Alimova, Florian L. Müller, Simona Colla, Luigi Nezi, Giannicola Genovese, Angela K. Deem, Avnish Kapoor, Wantong Yao, Emanuela Brunetto, Ya’an Kang, Min Yuan, John M. Asara, Yanru Wang, Timothy P. Heffernan, Alec C. Kimmelman, Huamin Wang, Jason B. Fleming, Lewis C. Cantley, Ronald A. DePinho, Giulio Draetta - Nature 2014 cited by 1,273

  9. Fatty acid synthesis is required for breast cancer brain metastasis

    Authors: Gino B. Ferraro, Ahmed Ali, Alba Luengo, David P. Kodack, Amy Deik, Keene L. Abbott, Divya Bezwada, Landry Blanc, Brendan Prideaux, Xin Jin, Jessica M. Posada, Jiang Chen, Christopher R. Chin, Zohreh Amoozgar, Raphaël Ferreira, Ivy X. Chen, Kamila Naxerova, Christopher Ng, Anna M. Westermark, Mark Duquette, Sylvie Roberge, Neal I. Lindeman, Costas A. Lyssiotis, Jens Nielsen, David E. Housman, Dan G. Duda, Elena F. Brachtel, Todd R. Golub, Lewis C. Cantley, John M. Asara, Shawn M. Davidson, Dai Fukumura, Véronique Dartois, Clary B. Clish, Rakesh K. Jain, Matthew G. Vander Heiden - Nature Cancer 2021 cited by 323

  10. mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

    Authors: Issam Ben‐Sahra, Gerta Hoxhaj, Stéphane J. H. Ricoult, John M. Asara, Brendan D. Manning - Science 2016 cited by 818

  11. A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

    Authors: Min Yuan, Susanne B. Breitkopf, Xuemei Yang, John M. Asara - Nature Protocols 2012 cited by 1,165

  12. Targeted deletion of PD-1 in myeloid cells induces antitumor immunity

    Authors: Laura Strauss, Mohamed A. A. Mahmoud, Jessica D. Weaver, Natalia M. Tijaro-Ovalle, Anthos Christofides, Qi Wang, Rinku Pal, Min Yuan, John M. Asara, Nikolaos Patsoukis, Vassiliki A. Boussiotis - Science Immunology 2020 cited by 441

  13. NRF2 regulates serine biosynthesis in non–small cell lung cancer

    Authors: Gina M. DeNicola, Pei-Hsuan Chen, Edouard Mullarky, Jessica Sudderth, Zeping Hu, David Wu, Hao Tang, Yang Xie, John M. Asara, Kenneth E. Huffman, Ignacio I. Wistuba, John D. Minna, Ralph J. DeBerardinis, Lewis C. Cantley - Nature Genetics 2015 cited by 778

  14. Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

    Authors: Jihye Yun, Edouard Mullarky, Changyuan Lu, Kaitlyn Bosch, Adam Kavalier, Keith Rivera, Jatin Roper, Iok In Christine Chio, Ευγενία Γιαννοπούλου, Carlo Rago, Ashlesha Muley, John M. Asara, Jihye Paik, Olivier Elemento, Zhengming Chen, Darryl Pappin, Lukas E. Dow, Nickolas Papadopoulos, Steven S. Gross, Lewis C. Cantley - Science 2015 cited by 920

  15. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer

    Authors: Lisa M. Becker, Joyce T. O’Connell, Annie P. Vo, Margo P. Cain, Désirée Tampe, Lauren Bizarro, Hikaru Sugimoto, Anna K. McGow, John M. Asara, Sara Lovisa, Kathleen M. McAndrews, Rafał Zieliński, Philip L. Lorenzi, Michael Zeisberg, Sughra Raza, Valerie S. LeBleu, Raghu Kalluri - Cell Reports 2020 cited by 283

  16. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

    Authors: Daniel F. Egan, Matthew G. H. Chun, Mitchell Vamos, Haixia Zou, Juan Rong, Chad J. Miller, Hua Jane Lou, Raveendra-Panickar Dhanya, Chih-Cheng Yang, Douglas J. Sheffler, Peter Teriete, John M. Asara, Benjamin E. Turk, Nicholas D. P. Cosford, Reuben J. Shaw - Molecular Cell 2015 cited by 723

  17. Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth

    Authors: Hongyun Zhao, Da Teng, Lifeng Yang, Xincheng Xu, Jiajia Chen, Teng‐Jia Jiang, Austin Y. Feng, Yaqing Zhang, Dennie T. Frederick, Lei Gu, Li Cai, John M. Asara, Marina Pasca di Magliano, Genevieve M. Boland, Keith T. Flaherty, Kenneth D. Swanson, David Liu, Joshua D. Rabinowitz, Bin Zheng - Nature Metabolism 2022 cited by 161

  18. MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

    Authors: Surendra K. Shukla, Vinee Purohit, Kamiya Mehla, Venugopal Gunda, Nina V. Chaika, Enza Vernucci, Ryan J. King, Jaime Abrego, Gennifer D. Goode, Aneesha Dasgupta, Alysha L. Illies, Teklab Gebregiworgis, Bingbing Dai, Jithesh J. Augustine, Divya Murthy, Kuldeep S. Attri, Oksana Mashadova, Paul M. Grandgenett, Robert Powers, Quan P. Ly, Audrey J. Lazenby, Jean L. Grem, Fang Yu, José M. Matés, John M. Asara, Jung‐whan Kim, Jordan Hankins, Colin D. Weekes, Michael A. Hollingsworth, Natalie J. Serkova, Aaron R. Sasson, Jason B. Fleming, Jennifer Oliveto, Costas A. Lyssiotis, Lewis C. Cantley, Lyudmyla Berim, Pankaj K. Singh - Cancer Cell 2017 cited by 551

  19. Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

    Authors: Dimitrios Anastasiou, George Poulogiannis, John M. Asara, Matthew B. Boxer, Jian‐kang Jiang, Min Shen, Gary Bellinger, Atsuo T. Sasaki, Jason W. Locasale, Douglas S. Auld, Craig J. Thomas, Matthew G. Vander Heiden, Lewis C. Cantley - Science 2011 cited by 1,201

  20. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

    Authors: Jason W. Locasale, Alexandra Grassian, Tamar Melman, Costas A. Lyssiotis, Katherine Mattaini, Adam J. Bass, Gregory J. Heffron, Christian M. Metallo, Taru Muranen, Hadar Sharfi, Atsuo T. Sasaki, Dimitrios Anastasiou, Edouard Mullarky, Natalie I. Vokes, Mika Sasaki, Rameen Beroukhim, Gregory Stephanopoulos, Azra H. Ligon, Matthew Meyerson, Andrea L. Richardson, Lynda Chin, Gerhard Wagner, John M. Asara, Joan S. Brugge, Lewis C. Cantley, Matthew G. Vander Heiden - Nature Genetics 2011 cited by 1,125

  21. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

    Authors: Dimitrios Anastasiou, Yimin Yu, William J. Israelsen, Jian‐kang Jiang, Matthew B. Boxer, Bum Soo Hong, W. Tempel, Svetoslav Dimov, Min Shen, Abhishek Jha, Hua Yang, Katherine Mattaini, Christian M. Metallo, Brian P. Fiske, Kevin D. Courtney, Scott Malstrom, Tahsin Khan, Charles Kung, Amanda P. Skoumbourdis, Henrike Veith, Noel Southall, Martin J. Walsh, Kyle R. Brimacombe, William Leister, Sophia Y. Lunt, Zachary Johnson, Katharine Yen, Kaiko Kunii, Shawn M. Davidson, Heather R. Christofk, Christopher P. Austin, James Inglese, Marian H. Harris, John M. Asara, Gregory Stephanopoulos, Francesco G. Salituro, Shengfang Jin, Lenny Dang, Douglas S. Auld, Hee‐Won Park, Lewis C. Cantley, Craig J. Thomas, Matthew G. Vander Heiden - Nature Chemical Biology 2012 cited by 825

  22. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

    Authors: Samuel K. McBrayer, Jared R. Mayers, Gabriel J. DiNatale, Diana D. Shi, Januka Khanal, Abhishek A. Chakraborty, Kristopher A. Sarosiek, Kimberly J. Briggs, Alissa K. Robbins, Tomasz Sewastianik, Sarah J. Shareef, Benjamin A. Olenchock, Seth J. Parker, Kensuke Tateishi, Jessica B. Spinelli, Mirazul Islam, Marcia C. Haigis, Ryan Looper, Keith L. Ligon, B Bernstein, Ruben D. Carrasco, Daniel P. Cahill, John M. Asara, Christian M. Metallo, Neela H. Yennawar, Matthew G. Vander Heiden, William G. Kaelin - Cell 2018 cited by 374

  23. Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1

    Authors: Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C. Erickson, Alissandra L. Hillis, Christian C. Dibble, John M. Asara, Gyongy Szabo, Piotr Siciński, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J. Shaw, Junying Yuan, Wenyi Wei - Science 2023 cited by 118

  24. GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

    Authors: Daniel M. Kremer, Barbara Scott Nelson, Lin Lin, Emily L. Yarosz, Christopher J. Halbrook, Samuel A. Kerk, Peter Sajjakulnukit, Amy L. Myers, Galloway Thurston, Sean W. Hou, Eileen S. Carpenter, Anthony Andren, Zeribe C. Nwosu, Nicholas Cusmano, Stephanie Wisner, Nneka E. Mbah, Mengrou Shan, Nupur K. Das, Brian Magnuson, Andrew C. Little, Milan R. Savani, Johanna Ramos, Tina Gao, Stephen A. Sastra, Carmine F. Palermo, Michael A. Badgley, Li Zhang, John M. Asara, Samuel K. McBrayer, Marina Pasca di Magliano, Howard C. Crawford, Yatrik M. Shah, Kenneth P. Olive, Costas A. Lyssiotis - Nature Communications 2021 cited by 256