Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Authors: Dimitrios Anastasiou, Yimin Yu, William J. Israelsen, Jian‐kang Jiang, Matthew B. Boxer, Bum Soo Hong, W. Tempel, Svetoslav Dimov, Min Shen, Abhishek Jha, Hua Yang, Katherine Mattaini, Christian M. Metallo, Brian P. Fiske, Kevin D. Courtney, Scott Malstrom, Tahsin Khan, Charles Kung, Amanda P. Skoumbourdis, Henrike Veith, Noel Southall, Martin J. Walsh, Kyle R. Brimacombe, William Leister, Sophia Y. Lunt, Zachary Johnson, Katharine Yen, Kaiko Kunii, Shawn M. Davidson, Heather R. Christofk, Christopher P. Austin, James Inglese, Marian H. Harris, John M. Asara, Gregory Stephanopoulos, Francesco G. Salituro, Shengfang Jin, Lenny Dang, Douglas S. Auld, Hee‐Won Park, Lewis C. Cantley, Craig J. Thomas, Matthew G. Vander Heiden - Nature Chemical Biology 2012 cited by 825