Christopher P. Austin
Active 1962–2024
- 138
- Papers
- 28,098
- Citations
- 92
- h-index
- 136
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology36.5%
- Medicine24.9%
- Computer Science14.3%
- Neuroscience7.4%
- Engineering3.8%
- Immunology and Microbiology2.7%
- Other10.4%
Topics
- Computational Drug Discovery Methods6.6%
- Retinal Development and Disorders2.2%
- 3D Printing in Biomedical Research1.5%
- Cancer, Hypoxia, and Metabolism1.4%
- Receptor Mechanisms and Signaling1.2%
- Bioinformatics and Genomic Networks1.1%
- Other86%
Coauthors
- Ruili Huang36
- Anton Simeonov30
- James Inglese30
- Menghang Xia30
- Ajit Jadhav21
- Noel Southall20
- Raymond R. Tice17
- David J. Figueroa15
- Douglas S. Auld15
- Wei Zheng15
- Craig J. Thomas13
- Paul Shinn12
- Srilatha Sakamuru11
- Qingyun Liu10
- Min Shen9
- David L. Williams8
- Jilly F. Evans8
- Robert J. Kavlock8
- Matias S. Attene‐Ramos7
- Ronald L. Johnson7
- William Leister7
- Andrew D. Howard6
- Henrike Veith6
- Kristine L. Witt6
All papers
- Organs-on-chips: into the next decade
Authors: Lucie A. Low, Christine L. Mummery, Brian R. Berridge, Christopher P. Austin, Danilo A. Tagle - Nature Reviews Drug Discovery 2020 cited by 928
- The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment
Authors: Melissa A. Haendel, Christopher G. Chute, Tellen D. Bennett, David A. Eichmann, Justin Guinney, Warren A. Kibbe, Philip R. O. Payne, Emily R. Pfaff, Peter N. Robinson, Joel H. Saltz, Heidi Spratt, Christine Suver, John Wilbanks, Adam B. Wilcox, Andrew E. Williams, Chunlei Wu, Clair Blacketer, Robert L. Bradford, James J. Cimino, Marshall Clark, Evan W. Colmenares, Patricia A. Francis, Davera Gabriel, Alexis Graves, Raju Hemadri, Stephanie S. Hong, George Hripcsak, Dazhi Jiao, Jeffrey G. Klann, Kristin Kostka, Adam M. Lee, Harold P. Lehmann, Lora Lingrey, Robert T. Miller, Michele Morris, Shawn N. Murphy, Karthik Natarajan, Matvey B. Palchuk, Usman Sheikh, Harold Solbrig, Shyam Visweswaran, Anita Walden, Kellie M. Walters, Griffin M. Weber, Xiaohan Tanner Zhang, Richard L. Zhu, Benjamin R. C. Amor, Andrew T. Girvin, Amin Manna, Nabeel Qureshi, Michael G. Kurilla, Sam G. Michael, Lili M. Portilla, Joni L. Rutter, Christopher P. Austin, Kenneth R. Gersing - Journal of the American Medical Informatics Association, J. Am. Medical Informatics Assoc. 2020 cited by 588
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Authors: Dimitrios Anastasiou, Yimin Yu, William J. Israelsen, Jian‐kang Jiang, Matthew B. Boxer, Bum Soo Hong, W. Tempel, Svetoslav Dimov, Min Shen, Abhishek Jha, Hua Yang, Katherine Mattaini, Christian M. Metallo, Brian P. Fiske, Kevin D. Courtney, Scott Malstrom, Tahsin Khan, Charles Kung, Amanda P. Skoumbourdis, Henrike Veith, Noel Southall, Martin J. Walsh, Kyle R. Brimacombe, William Leister, Sophia Y. Lunt, Zachary Johnson, Katharine Yen, Kaiko Kunii, Shawn M. Davidson, Heather R. Christofk, Christopher P. Austin, James Inglese, Marian H. Harris, John M. Asara, Gregory Stephanopoulos, Francesco G. Salituro, Shengfang Jin, Lenny Dang, Douglas S. Auld, Hee‐Won Park, Lewis C. Cantley, Craig J. Thomas, Matthew G. Vander Heiden - Nature Chemical Biology 2012 cited by 825
- The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology
Authors: Ann M. Richard, Ruili Huang, Suramya Waidyanatha, Paul Shinn, Bradley J. Collins, Inthirany Thillainadarajah, Chris Grulke, Antony Williams, Ryan Lougee, Richard Judson, Keith A. Houck, Mahmoud Shobair, Chihae Yang, James F. Rathman, Adam Yasgar, Suzanne Fitzpatrick, Anton Simeonov, Russell S. Thomas, Kevin M. Crofton, Richard S. Paules, John R. Bucher, Christopher P. Austin, Robert J. Kavlock, Raymond R. Tice - Chemical Research in Toxicology 2020 cited by 310
- Therapies for rare diseases: therapeutic modalities, progress and challenges ahead
Authors: Erik Tambuyzer, Benjamin Vandendriessche, Christopher P. Austin, Philip J. Brooks, Kristina Larsson, Katherine I. Miller Needleman, James Valentine, Kay E. Davies, Stephen C. Groft, Robert A. Preti, Tudor I. Oprea, Marco Prunotto - Nature Reviews Drug Discovery 2019 cited by 351
- The promise and peril of chemical probes
Authors: C.H. Arrowsmith, James E. Audia, Christopher P. Austin, Jonathan B. Baell, Jonathan P. Bennett, Julian Blagg, C. Bountra, Paul E. Brennan, Peter J. Brown, Mark E. Bunnage, Carolyn Buser‐Doepner, Robert M Campbell, Adrian J. Carter, Philip Cohen, Robert A. Copeland, Ben Cravatt, Jayme L. Dahlin, Dashyant Dhanak, A.M. Edwards, Mathias Frederiksen, Stephen V. Frye, Nathanael S. Gray, Charles E. Grimshaw, David Hepworth, Trevor Howe, K. Huber, Jian Jin, Stefan Knapp, Joanne Kotz, Ryan G. Kruger, Derek Lowe, Mary M. Mader, Brian D. Marsden, Anke Mueller‐Fahrnow, Susanne Müller, Rónán C. O’Hagan, John P. Overington, Dafydd R. Owen, Saul H. Rosenberg, Ruth A. Ross, Bryan L. Roth, Matthieu Schapira, Stuart L. Schreiber, Brian K. Shoichet, M. Sundström, Giulio Superti-Furga, Jack Taunton, Leticia Toledo‐Sherman, Chris Walpole, Michael A. Walters, Timothy M. Willson, Paul Workman, Robert N. Young, William J. Zuercher - Nature Chemical Biology 2015 cited by 850
- The NCATS BioPlanet – An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics
Authors: Ruili Huang, Ivan Grishagin, Yuhong Wang, Tongan Zhao, Jon Greene, John C. Obenauer, Deborah K. Ngan, Ðắc-Trung Nguyễn, Rajarshi Guha, Ajit Jadhav, Noel Southall, Anton Simeonov, Christopher P. Austin - Frontiers in Pharmacology 2019 cited by 320
- Future of Rare Diseases Research 2017–2027: An IRDiRC Perspective
Authors: Christopher P. Austin, Christine M. Cutillo, Lilian Pek Lian Lau, Anneliene Hechtelt Jonker, Ana Rath, Daria Julkowska, David Thomson, Sharon F. Terry, Béatrice de Montleau, Diego Ardigò, Virginie Hivert, Kym M. Boycott, Gareth Baynam, Petra Kaufmann, Domenica Taruscio, Hanns Lochmüller, Makoto Suematsu, Carlo Incerti, Ruxandra Draghia‐Akli, Iréne Norstedt, Lu Wang, Hugh Dawkins - Clinical and Translational Science 2017 cited by 249
- Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries
Authors: James Inglese, Douglas S. Auld, Ajit Jadhav, Ronald L. Johnson, Anton Simeonov, Adam Yasgar, Wei Zheng, Christopher P. Austin - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 820
- Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries
Authors: Henrike Veith, Noel Southall, Ruili Huang, Tim James, Darren Fayne, Natalia V. Artemenko, Min Shen, James Inglese, Christopher P. Austin, David G. Lloyd, Douglas S. Auld - Nature Biotechnology 2009 cited by 219
- A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells
Authors: Yu Chen, Carlos A. Tristan, Lu Chen, Vukasin M. Jovanovic, Claire Malley, Pei‐Hsuan Chu, Seungmi Ryu, Tao Deng, Pinar Ormanoglu, Dingyin Tao, Yuhong Fang, Jaroslav Slamecka, Hyenjong Hong, Christopher A. LeClair, Sam Michael, Christopher P. Austin, Anton Simeonov, Ilyas Singeç - Nature Methods 2021 cited by 186
- Improving the Human Hazard Characterization of Chemicals: A Tox21 Update
Authors: Raymond R. Tice, Christopher P. Austin, Robert J. Kavlock, John R. Bucher - Environmental Health Perspectives 2013 cited by 612
- Opportunities and challenges in translational science
Authors: Christopher P. Austin - Clinical and Translational Science 2021 cited by 167
- Assay Guidance Manual [Internet]
Authors: Sarine Markossian, A Grossman, Kyle R. Brimacombe, Michelle R. Arkin, Douglas S. Auld, Christopher P. Austin, Jonathan B. Baell, Thomas D.Y. Chung, Nathan P. Coussens, Jayme L. Dahlin, Viswanath Devanarayan, Timothy L. Foley, Marcie A. Glicksman, Matthew D. Hall, Joseph V. Haas, Sam R.J. Hoare, James Inglese, Philip W. Iversen, Stephen C. Kales, Madhu Lal‐Nag, Zhuyin Li, J McGee, Owen B. McManus, Terry Riss, P Saradjian, G. Sitta Sittampalam, Mike Tarselli, O. Joseph Trask, Yueming Wang, Jeffrey R. Weidner, Mary Jo Wildey, Kelli M. Wilson, Menghang Xia, Xin Xu - 2004 cited by 287
- Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative
Authors: Tellen D. Bennett, Richard A. Moffitt, Janos Hajagos, Benjamin Amor, Adit Anand, Mark M. Bissell, Katie R. Bradwell, Carolyn Bremer, James Brian Byrd, Alina Denham, Peter E. DeWitt, Davera Gabriel, Brian T. Garibaldi, Andrew T. Girvin, Justin Guinney, Elaine Hill, Stephanie Hong, Hunter Jimenez, Ramakanth Kavuluru, Kristin Kostka, Harold P. Lehmann, Eli Levitt, Sandeep K. Mallipattu, Amin Manna, Julie A. McMurry, Michele Morris, John Muschelli, Andrew J. Neumann, Matvey B. Palchuk, Emily Pfaff, Zhenglong Qian, Nabeel Qureshi, Seth Russell, Heidi Spratt, Anita Walden, Andrew E. Williams, Jacob T. Wooldridge, Yun Jae Yoo, Xiaohan Tanner Zhang, Richard L. Zhu, Christopher P. Austin, Joel Saltz, Kenneth Gersing, Melissa Haendel, Christopher G. Chute, Joel Gagnier, Siqing Hu, Kanchan Lota, Sarah E. Maidlow, David A. Hanauer, Kevin J. Weatherwax, Nikhila Gandrakota, Rishikesan Kamaleswaran, Greg S. Martin, Jingjing Qian, Jason E. Farley, Patricia A. Francis, Dazhi Jiao, Hadi Kharrazi, Justin Reese, Mariam Deacy, Usman Ullah Sheikh, Jake Y. Chen, Michael Quinn Patton, T. Bennett Ramsey, Jasvinder A. Singh, James J. Cimino, Jing Su, William G. Adams, Timothy Q. Duong, John B. Buse, Jessica Y. Islam, Jihad S. Obeid, Stephane Meystre, Steve Patterson, Misha Zemmel, Ron Grider, A. Pérez Martínez, Carlos Antônio do Nascimento Santos, Julian Solway, Ryan G. Chiu, Gerald B. Brown, Jia-Feng Cui, Sharon X. Liang, Kamil Khanipov, Jeremy Harper, Peter J. Embí, David Eichmann, Boyd M. Knosp, William B. Hillegass, Chunlei Wu, James R. Aaron, Darren W. Henderson, Muhammad Gul, Tamela Harper, Daniel R. Harris, Jeffery Talbert, Neil Bahroos, Steven M. Dubinett, Jomol Mathew and 69 more - JAMA Network Open 2021 cited by 247
- Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial
Authors: Daniel S. Ory, Elizabeth A. Ottinger, Nicole Y. Farhat, Kelly King, Xuntian Jiang, Lisa A. Weissfeld, Elizabeth Berry‐Kravis, Cristin Davidson, Simona Bianconi, Lee Ann Keener, Ravichandran Rao, Ariane Soldatos, Rohini Sidhu, Kimberly A. Walters, Xin Xu, Audrey Thurm, Beth Solomon, William J. Pavan, Bernardus N Machielse, Mark Kao, Steven A. Silber, John C. McKew, Carmen C. Brewer, Charles H. Vite, Steven U. Walkley, Christopher P. Austin, Forbes D. Porter - The Lancet 2017 cited by 325
- High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
Authors: Lesley A. Mathews Griner, Rajarshi Guha, Paul Shinn, Ryan M. Young, Jonathan M. Keller, Dongbo Liu, Ian S. Goldlust, Adam Yasgar, Crystal McKnight, Matthew B. Boxer, Damien Duveau, Jian‐kang Jiang, Sam Michael, Tim Mierzwa, Wenwei Huang, Martin J. Walsh, Bryan T. Mott, Paresma Patel, William Leister, David J. Maloney, Christopher A. LeClair, Ganesha Rai, Ajit Jadhav, Brian D. Peyser, Christopher P. Austin, Scott E. Martin, Anton Simeonov, Marc Ferrer, Louis M. Staudt, Craig J. Thomas - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 397
- Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
Authors: Ruili Huang, Menghang Xia, Srilatha Sakamuru, Jinghua Zhao, Sampada A. Shahane, Matias S. Attene‐Ramos, Tongan Zhao, Christopher P. Austin, Anton Simeonov - Nature Communications 2016 cited by 255
- Progress in Rare Diseases Research 2010–2016: An IRDiRC Perspective
Authors: Hugh Dawkins, Ruxandra Draghia‐Akli, Paul Lasko, Lilian Pek Lian Lau, Anneliene Hechtelt Jonker, Christine M. Cutillo, Ana Rath, Kym M. Boycott, Gareth Baynam, Hanns Lochmüller, Petra Kaufmann, Yann Le Cam, Virginie Hivert, Christopher P. Austin - Clinical and Translational Science 2017 cited by 190
- From scientific discovery to treatments for rare diseases – the view from the National Center for Advancing Translational Sciences – Office of Rare Diseases Research
Authors: Petra Kaufmann, Anne Pariser, Christopher P. Austin - Orphanet Journal of Rare Diseases 2018 cited by 157
- The Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality
Authors: Matias S. Attene‐Ramos, Nicole Miller, Ruili Huang, Sam Michael, Misha Itkin, Robert J. Kavlock, Christopher P. Austin, Paul Shinn, Anton Simeonov, Raymond R. Tice, Menghang Xia - Drug Discovery Today 2013 cited by 256
- High-throughput screening assays for the identification of chemical probes
Authors: James Inglese, Ronald L. Johnson, Anton Simeonov, Menghang Xia, Wei Zheng, Christopher P. Austin, Douglas S. Auld - Nature Chemical Biology 2007 cited by 618
- The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics
Authors: Ruili Huang, Noel Southall, Yuhong Wang, Adam Yasgar, Paul Shinn, Ajit Jadhav, Ðắc-Trung Nguyễn, Christopher P. Austin - Science Translational Medicine 2011 cited by 412
- Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
Authors: Warren Fiskus, Nakhle S. Saba, Min Shen, Mondana Ghias, Jinyun Liu, Soumyasri Das Gupta, Lata Chauhan, Rekha Rao, Sumedha Gunewardena, Kevin Schorno, Christopher P. Austin, Kami J. Maddocks, John C. Byrd, Ari Melnick, Peng Huang, Adrian Wiestner, Kapil N. Bhalla - Cancer Research 2014 cited by 246
