Jonathan C. Kagan
Active 2000–2025
- 90
- Papers
- 21,898
- Citations
- 63
- h-index
- 86
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology38.2%
- Immunology and Microbiology31.9%
- Medicine20.5%
- Agricultural and Biological Sciences2.6%
- Neuroscience2.3%
- Engineering1.1%
- Other3.4%
Topics
- Inflammasome and immune disorders8.8%
- Immune Response and Inflammation7.1%
- interferon and immune responses6.6%
- Immune Cell Function and Interaction2.6%
- Immune cells in cancer2.1%
- Heme Oxygenase-1 and Carbon Monoxide1.9%
- Other70.9%
Coauthors
- Pascal Devant12
- Charles L. Evavold11
- Hao Wu11
- Ivan Zanoni9
- Yunhao Tan7
- Craig R. Roy6
- Anh Cao5
- Charlotte Odendall5
- Dania Zhivaki5
- Judy Lieberman5
- Megan H. Orzalli5
- Anna E. Gauthier4
- Gang Du4
- Katherine A. Fitzgerald4
- Pietro Fontana4
- Ruslan Medzhitov4
- Weiyi Ma4
- Ying Dong4
- Evelyn Dixit3
- Gregory M. Barton3
- Hiroki Nagai3
- Iva Hafner‐Bratkovič3
- Jay R. Thiagarajah3
- Jianbin Ruan3
All papers
- Toll-like Receptors and the Control of Immunity
Authors: Katherine A. Fitzgerald, Jonathan C. Kagan - Cell 2020 cited by 2,168
- Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
Authors: Rui Miao, Cong Jiang, Winston Chang, Haiwei Zhang, Jinsu An, Felicia Ho, Pengcheng Chen, Han Zhang, Caroline Junqueira, Dulguun Amgalan, Felix G. Liang, Junbing Zhang, Charles L. Evavold, Iva Hafner‐Bratkovič, Zhibin Zhang, Pietro Fontana, Shiyu Xia, Markus Waldeck‐Weiermair, Youdong Pan, Thomas Michel, Liron Bar‐Peled, Hao Wu, Jonathan C. Kagan, Richard N. Kitsis, Peng Zhang, Xing Liu, Judy Lieberman - Immunity 2023 cited by 490
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
Authors: Charles L. Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C. Kagan - Immunity 2017 cited by 1,116
- Innate Immune Pattern Recognition: A Cell Biological Perspective
Authors: Sky W. Brubaker, Kevin S. Bonham, Ivan Zanoni, Jonathan C. Kagan - Annual Review of Immunology 2015 cited by 1,420
- Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
Authors: Charles L. Evavold, Iva Hafner‐Bratkovič, Pascal Devant, Jasmin M. D’Andrea, Elsy M. Ngwa, Elvira Boršić, John G. Doench, Martin W. LaFleur, Arlene H. Sharpe, Jay R. Thiagarajah, Jonathan C. Kagan - Cell 2021 cited by 417
- ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D
Authors: Gang Du, Liam B. Healy, Liron David, Caitlin Walker, Tarick J. El‐Baba, Corinne A. Lutomski, Byoungsook Goh, Bowen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R. Luo, Jonathan C. Kagan, Sungwhan F. Oh, Carol V. Robinson, Judy Lieberman, Hao Wu - Nature 2024 cited by 233
- Molecular mechanisms of gasdermin D pore-forming activity
Authors: Pascal Devant, Jonathan C. Kagan - Nature Immunology 2023 cited by 246
- HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
Authors: Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, Arthur V. Hauenstein, Giuseppe Di Caprio, Wesley Skillern, Qiufang Deng, Pontus Ørning, Hasan B. Alam, Zoltan Maliga, Humayun Sharif, Jun Hu, Charles L. Evavold, Jonathan C. Kagan, Florian I. Schmidt, Katherine A. Fitzgerald, Tomas Kirchhausen, Yongqing Li, Hao Wu - Science 2020 cited by 383
- Targeting innate immune pathways for cancer immunotherapy
Authors: Longyue L. Cao, Jonathan C. Kagan - Immunity 2023 cited by 199
- An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
Authors: Ivan Zanoni, Yunhao Tan, Marco Di Gioia, Achille Broggi, Jianbin Ruan, Jianjin Shi, Carlos Donado, Feng Shao, Hao Wu, James R. Springstead, Jonathan C. Kagan - Science 2016 cited by 579
- The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis
Authors: Arumugam Balasubramanian, Alan Y. Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A. Trauger, Martin R. Larsen, Wenyi Wei, Hao Wu, Jonathan C. Kagan, Judy Lieberman, Hongbo R. Luo - Science Immunology 2024 cited by 177
- CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4
Authors: Ivan Zanoni, Renato Ostuni, Lorri R. Marek, Simona Barresi, Roman Barbalat, Gregory M. Barton, Francesca Granucci, Jonathan C. Kagan - Cell 2011 cited by 1,009
- Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity
Authors: Chaoyu Wang, Ruoshi Zhang, Jia He, Lvshan Yu, Xinyan Li, Junxia Zhang, Sai Li, Conggang Zhang, Jonathan C. Kagan, Jeffrey M. Karp, Rui Kuai - Nature Communications 2023 cited by 161
- Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA
Authors: Katherine C. Barnett, Julia María Coronas-Serna, Wen Zhou, Michael J. Ernandes, Anh Cao, Philip J. Kranzusch, Jonathan C. Kagan - Cell 2019 cited by 278
- Gasdermin D pore-forming activity is redox-sensitive
Authors: Pascal Devant, Elvira Boršić, Elsy M. Ngwa, Haopeng Xiao, Edward T. Chouchani, Jay R. Thiagarajah, Iva Hafner‐Bratkovič, Charles L. Evavold, Jonathan C. Kagan - Cell Reports 2023 cited by 131
- TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Authors: Jonathan C. Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira, Ruslan Medzhitov - Nature Immunology 2008 cited by 1,248
- Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
Authors: Jazlyn P. Borges, Ragnhild SR Sætra, Allen Volchuk, Marit Bugge, Pascal Devant, Bjørnar Sporsheim, Bridget R Kilburn, Charles L. Evavold, Jonathan C. Kagan, Neil M. Goldenberg, Trude Helen Flo, Benjamin E. Steinberg - eLife 2022 cited by 121
- Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity
Authors: Dania Zhivaki, Francesco Borriello, Ohn A. Chow, Benjamin A. Doran, Ira Fleming, Derek J. Theisen, Paris Pallis, Alex K. Shalek, Caroline L. Sokol, Ivan Zanoni, Jonathan C. Kagan - Cell Reports 2020 cited by 163
- Structural insights into cytokine cleavage by inflammatory caspase-4
Authors: Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P. Gygi, Hao Wu, Jonathan C. Kagan - Nature 2023 cited by 80
- Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation
Authors: Carina C. de Oliveira Mann, Megan H. Orzalli, David S. King, Jonathan C. Kagan, Amy S.Y. Lee, Philip J. Kranzusch - Cell Reports 2019 cited by 218
- Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity
Authors: Evelyn Dixit, Steeve Boulant, Yijing Zhang, Amy S.Y. Lee, Charlotte Odendall, Bennett O. V. Shum, Nir Hacohen, Zhijian J. Chen, Sean P. J. Whelan, Marc Fransen, Max L. Nibert, Giulio Superti‐Furga, Jonathan C. Kagan - Cell 2010 cited by 822
- By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation
Authors: Ivan Zanoni, Yunhao Tan, Marco Di Gioia, James R. Springstead, Jonathan C. Kagan - Immunity 2017 cited by 223
- Correction of age-associated defects in dendritic cells enables CD4+ T cells to eradicate tumors
Authors: Dania Zhivaki, Stephanie N. Kennedy, J. Park, Francesco Boriello, Pascal Devant, Anh Cao, Kristin M. Bahleda, Shane Murphy, Cristin McCabe, Charles L. Evavold, Kate L. Chapman, Ivan Zanoni, Orr Ashenberg, Ramnik J. Xavier, Jonathan C. Kagan - Cell 2024 cited by 81
- SMOCs: supramolecular organizing centres that control innate immunity
Authors: Jonathan C. Kagan, Venkat Giri Magupalli, Hao Wu - Nature reviews. Immunology 2014 cited by 306
