Kenneth E. Thummel
Active 1990–2024
- 121
- Papers
- 22,364
- Citations
- 85
- h-index
- 121
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine43.9%
- Pharmacology, Toxicology and Pharmaceutics39.4%
- Biochemistry, Genetics and Molecular Biology8.5%
- Engineering2.1%
- Computer Science2%
- Environmental Science0.8%
- Other3.3%
Topics
- Pharmacogenetics and Drug Metabolism16.5%
- Drug Transport and Resistance Mechanisms9.5%
- Pharmacological Effects and Toxicity Studies4.4%
- Drug-Induced Hepatotoxicity and Protection3%
- Computational Drug Discovery Methods2.9%
- Renal Transplantation Outcomes and Treatments1.8%
- Other61.9%
Coauthors
- Danny D. Shen21
- Kent L. Kunze19
- Mary F. Paine18
- Evan D. Kharasch17
- Erin G. Schuetz16
- Paul B. Watkins15
- Yvonne S. Lin15
- Allan E. Rettie11
- Mary F. Hébert11
- Connie L. Davis9
- Jashvant D. Unadkat8
- Christopher L. Marsh7
- Jatinder K. Lamba7
- Nina Isoherranen7
- Sidney D. Nelson7
- Steven Wrighton7
- Catherine K. Yeung6
- Deborah A. Nickerson6
- Edward J. Kelly6
- Jeannine M. Fisher6
- Kenneth S. Lown6
- Zhican Wang6
- James D. Perkins5
- John T. Slattery5
All papers
- Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
Authors: Peter Kuehl, Jiong Zhang, Yvonne Lin, Jatinder K. Lamba, Mahfoud Assem, John D. Schuetz, Paul B. Watkins, Ann K. Daly, Steven Wrighton, Stephen D. Hall, P Maurel, Mary V. Relling, Cynthia Brimer, Kazuto Yasuda, Raman Venkataramanan, Stephen C. Strom, Kenneth E. Thummel, Mark S. Boguski, Erin G. Schuetz - Nature Genetics 2001 cited by 2,161
- Development of a microphysiological model of human kidney proximal tubule function
Authors: Elijah J. Weber, Alenka Chapron, Brian D. Chapron, Jenna L. Voellinger, Kevin A. Lidberg, Catherine K. Yeung, Zhican Wang, Yoshiyuki Yamaura, Dale W. Hailey, Thomas Neumann, Danny D. Shen, Kenneth E. Thummel, Kimberly A. Muczynski, Jonathan Himmelfarb, Edward J. Kelly - Kidney International 2016 cited by 267
- Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants
Authors: Sumit Bansal, C. Austin Zamarripa, Tory R. Spindle, Elise M. Weerts, Kenneth E. Thummel, Ryan G. Vandrey, Mary F. Paine, Jashvant D. Unadkat - Clinical Pharmacology & Therapeutics 2023 cited by 62
- Genetic contribution to variable human CYP3A-mediated metabolism
Authors: Jatinder K. Lamba, Yvonne S. Lin, Erin G. Schuetz, Kenneth E. Thummel - Advanced Drug Delivery Reviews 2002 cited by 992
- Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
Authors: Rakshit S. Tanna, James Nguyen, Deena L. Hadi, Preston K. Manwill, Laura Flores‐Bocanegra, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine - Pharmaceutics 2022 cited by 64
- Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model
Authors: Seung‐been Lee, Marsha M. Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L. Woodahl, Andrea Gaedigk, Kenneth E. Thummel, Deborah A. Nickerson - Genetics in Medicine 2018 cited by 151
- CYP3A4 mutation causes vitamin D–dependent rickets type 3
Authors: Jeffrey D. Roizen, Dong Li, Lauren O’Lear, M K Javaid, Nicholas J Shaw, Peter R. Ebeling, Hanh H. Nguyen, Christine Rodda, Kenneth E. Thummel, Tom D. Thacher, Håkon Håkonarson, Michael A. Levine - Journal of Clinical Investigation 2018 cited by 118
- Cyp2e1 Activity Before and After Weight Loss in Morbidly Obese Subjects With Nonalcoholic Fatty Liver Disease
Authors: Maurice G. Emery, Jeannine M. Fisher, Jenny Chien, Evan D. Kharasch, Patchen Dellinger, Kris V. Kowdley, Kenneth E. Thummel - Hepatology 2003 cited by 176
- Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
Authors: T. S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao‐bo Zhong, Yin-Chun Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer, Yvonne S Lin - Drug Metabolism and Disposition 2015 cited by 175
- Drug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?
Authors: Nina Isoherranen, Kenneth E. Thummel - Drug Metabolism and Disposition 2013 cited by 208
- Interplay between vitamin D and the drug metabolizing enzyme CYP3A4
Authors: Zhican Wang, Erin G. Schuetz, Yang Xu, Kenneth E. Thummel - The Journal of Steroid Biochemistry and Molecular Biology 2012 cited by 123
- Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences
Authors: Seung‐been Lee, Marsha M. Wheeler, Kenneth E. Thummel, Deborah A. Nickerson - Clinical Pharmacology & Therapeutics 2019 cited by 92
- Assessing Transporter‐Mediated Natural Product‐Drug Interactions Via In vitro‐In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail
Authors: James Nguyen, Dandan Tian, Rakshit S. Tanna, Deena L. Hadi, Sumit Bansal, Justina C. Calamia, Christopher M. Arian, Laura M. Shireman, Bálint Molnár, Miklós Horváth, Joshua J. Kellogg, Matthew E. Layton, John R. White, Nadja B. Cech, Richard D. Boyce, Jashvant D. Unadkat, Kenneth E. Thummel, Mary F. Paine - Clinical Pharmacology & Therapeutics 2020 cited by 39
- Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom
Authors: Rakshit S. Tanna, James Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine - Clinical Pharmacology & Therapeutics 2023 cited by 27
- Interpreting Tacrolimus Concentrations During Pregnancy and Postpartum
Authors: Mary F. Hébert, Songmao Zheng, Karen Hays, Danny D. Shen, Connie L. Davis, Jason G. Umans, Menachem Miodovnik, Kenneth E. Thummel, Thomas R. Easterling - Transplantation 2012 cited by 144
- CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations
Authors: Colin P. Hawkes, Dong Li, Håkon Håkonarson, Kevin Meyers, Kenneth E. Thummel, Michael A. Levine - The Journal of Clinical Endocrinology & Metabolism 2017 cited by 100
- Translating Kratom-Drug Interactions: From Bedside to Bench and Back
Authors: Rakshit S. Tanna, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine - Drug Metabolism and Disposition 2023 cited by 24
- New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process
Authors: Shiew‐Mei Huang, John M. Strong, Lei Zhang, Kellie S. Reynolds, Srikanth C. Nallani, Robert Temple, Sophia Abraham, Sayed Al Habet, Raman Baweja, Gilbert J. Burckart, Sang M. Chung, Philip M. Colangelo, David M. Frucht, Martin D. Green, Paul Hepp, Elena Karnaukhova, Hee Gyeong Ko, Jang-ik Lee, Patrick Marroum, Janet M. Norden, Wei Qiu, Atiqur Rahman, Solomon Sobel, Toni Stifano, Kenneth E. Thummel, Xiaoxiong Wei, Sally Usdin Yasuda, Jenny Zheng, Hong Zhao, Lawrence J. Lesko - The Journal of Clinical Pharmacology 2008 cited by 400
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing
Authors: Kelly A. Birdwell, Brian S. Decker, Julia M. Barbarino, Josh F. Peterson, C. Michael Stein, Wolfgang Sadée, Daqing Wang, Alexander A. Vinks, Yijing He, Jesse J. Swen, J. Steven Leeder, RHN van Schaik, Kenneth E. Thummel, Teri E. Klein, Kelly E. Caudle, Iain MacPhee - 2015 cited by 88
- Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*
Authors: Kenneth E. Thummel, Diarmuid O’Shea, Mary F. Paine, Danny D. Shen, Kent L. Kunze, James D. Perkins, G. Wilkinson - Clinical Pharmacology & Therapeutics 1996 cited by 619
- Transcriptional Control of Intestinal Cytochrome P-4503A by 1α,25-Dihydroxy Vitamin D3
Authors: Kenneth E. Thummel, Cynthia Brimer, Kazuto Yasuda, Jaideep V. Thottassery, Tauri Senn, Yvonne Lin, Hitoshi Ishizuka, Evan D. Kharasch, John D. Schuetz, Erin G. Schuetz - Molecular Pharmacology 2001 cited by 324
- ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
Authors: Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson, Kenneth E. Thummel - Drug Metabolism and Disposition 2004 cited by 275
- Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport
Authors: Catherine K. Yeung, Danny D. Shen, Kenneth E. Thummel, Jonathan Himmelfarb - Kidney International 2013 cited by 213
- An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway
Authors: Zhican Wang, Yvonne S. Lin, Xi Zheng, Tauri Senn, Takanori Hashizume, Michele Scian, Leslie J. Dickmann, Sidney D. Nelson, Thomas A. Baillie, Mary F. Hébert, David K. Blough, Connie L. Davis, Kenneth E. Thummel - Molecular Pharmacology 2011 cited by 114
