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Steven Wrighton

Active 1984–2011

86
Papers
18,813
Citations
77
h-index
86
i10-index

Citations

Citations per year for Steven Wrighton1983: 3 citations1984: 2 citations1985: 4 citations1986: 25 citations1987: 29 citations1988: 29 citations1989: 59 citations1990: 86 citations1991: 46 citations1992: 81 citations1993: 84 citations1994: 79 citations1995: 126 citations1996: 122 citations1997: 204 citations1998: 192 citations1999: 193 citations2000: 201 citations2001: 224 citations2002: 322 citations2003: 317 citations2004: 340 citations2005: 362 citations2006: 322 citations2007: 229 citations2008: 220 citations2009: 182 citations2010: 150 citations2011: 140 citations2012: 152 citations2013: 126 citations2014: 112 citations2015: 109 citations2016: 78 citations2017: 53 citations2018: 45 citations2019: 189 citations2020: 185 citations2021: 203 citations2022: 101 citations2023: 69 citations2024: 120 citations2025: 38 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,856 citing papers, 36.2% of this breakdownUnited Kingdom: 407 citing papers, 7.9% of this breakdownGermany: 277 citing papers, 5.4% of this breakdownJapan: 271 citing papers, 5.3% of this breakdownChina: 250 citing papers, 4.9% of this breakdownFrance: 183 citing papers, 3.6% of this breakdownCanada: 177 citing papers, 3.4% of this breakdownSweden: 170 citing papers, 3.3% of this breakdownNetherlands: 154 citing papers, 3% of this breakdownItaly: 122 citing papers, 2.4% of this breakdownAustralia: 116 citing papers, 2.3% of this breakdownSwitzerland: 112 citing papers, 2.2% of this breakdown
0%36.2%Other 20.1%

Institutions

Fields

  • Pharmacology, Toxicology and Pharmaceutics44.1%
  • Medicine34.7%
  • Biochemistry, Genetics and Molecular Biology8.9%
  • Computer Science7.1%
  • Chemistry1.3%
  • Environmental Science1.2%
  • Other2.7%

Topics

  • Pharmacogenetics and Drug Metabolism19.8%
  • Drug Transport and Resistance Mechanisms10.5%
  • Computational Drug Discovery Methods6.1%
  • Pharmacological Effects and Toxicity Studies3.4%
  • Drug-Induced Hepatotoxicity and Protection2.9%
  • Analytical Chemistry and Chromatography2.2%
  • Other55.1%

Coauthors

All papers

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  1. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

    Authors: Peter Kuehl, Jiong Zhang, Yvonne Lin, Jatinder K. Lamba, Mahfoud Assem, John D. Schuetz, Paul B. Watkins, Ann K. Daly, Steven Wrighton, Stephen D. Hall, P Maurel, Mary V. Relling, Cynthia Brimer, Kazuto Yasuda, Raman Venkataramanan, Stephen C. Strom, Kenneth E. Thummel, Mark S. Boguski, Erin G. Schuetz - Nature Genetics 2001 cited by 2,161

  2. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

    Authors: Daqing Wang, Yingying Guo, Steven Wrighton, George Cooke, Wolfgang Sadée - The Pharmacogenomics Journal 2010 cited by 507

  3. THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

    Authors: Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence L. Gan, Scott Grimm, John Y. Kao, Shang‐Ying P. King, Gerald T. Miwa, Lan Ni, Gondi Kumar, James F. McLeod, R. Scott Obach, Stanley Roberts, Amy L. Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, José M. Vega, John Walsh, Steven Wrighton - Drug Metabolism and Disposition 2003 cited by 784

  4. Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7

    Authors: J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, David R. Jones, James A. Eckstein, Kenneth J. Ruterbories, Mitchell A. Hamman, Stephen D. Hall, Steven Wrighton - Drug Metabolism and Disposition 2002 cited by 468

  5. Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression

    Authors: Vishal Lamba, Jatinder K. Lamba, Kazuto Yasuda, Stephen C. Strom, Julio Dávila, Michael L. Hancock, James D. Fackenthal, Peter K. Rogan, Barbara J. Ring, Steven Wrighton, Erin G. Schuetz - Journal of Pharmacology and Experimental Therapeutics 2003 cited by 400

  6. Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans

    Authors: Nagy A. Farid, Atsushi Kurihara, Steven Wrighton - The Journal of Clinical Pharmacology 2009 cited by 391

  7. Present and future in vitro approaches for drug metabolism

    Authors: Sean Ekins, Barbara J. Ring, James E. Grace, Donna J. McRobie-Belle, Steven Wrighton - Journal of Pharmacological and Toxicological Methods 2000 cited by 227

  8. The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

    Authors: Steven Wrighton, Jeffrey Stevens - Critical Reviews in Toxicology 1992 cited by 947

  9. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

    Authors: Paul B. Watkins, Steven Wrighton, Erin G. Schuetz, David T. Molowa, Philip S. Guzelian - Journal of Clinical Investigation 1987 cited by 483

  10. Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.

    Authors: Paul B. Watkins, Scott A Murray, L G Winkelman, Douglas M. Heuman, Steven Wrighton, Philip S. Guzelian - Journal of Clinical Investigation 1989 cited by 351

  11. In Vitro Glucuronidation Using Human Liver Microsomes and The Pore-Forming Peptide Alamethicin

    Authors: Michael B. Fisher, Kristina Campanale, Bradley L. Ackermann, Mark VandenBranden, Steven Wrighton - Drug Metabolism and Disposition 2000 cited by 342

  12. The Conduct of In Vitro and In Vivo Drug‐Drug Interaction Studies: A PhRMA Perspective

    Authors: Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence L. Gan, Scott Grimm, John Y. Kao, Shang‐Ying P. King, Gerald T. Miwa, Lan Ni, Gondi Kumar, James F. McLeod, Scott R. Obach, Stanley Roberts, Amy L. Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, José M. Vega, John Walsh, Steven Wrighton - The Journal of Clinical Pharmacology 2003 cited by 309

  13. Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

    Authors: Paul B. Watkins, Steven Wrighton, Jeffrey L. Barnett, Kenneth S. Lown, Kent L. Kunze, Kenneth E. Thummel, Joseph C. Kolars - Drug Metabolism and Disposition 1994 cited by 305

  14. Progress in predicting human ADME parameters in silico

    Authors: Sean Ekins, Chris L. Waller, Peter W. Swaan, Gabriele Cruciani, Steven Wrighton, James H. Wikel - Journal of Pharmacological and Toxicological Methods 2000 cited by 277

  15. Molecular and physical mechanisms of first-pass extraction.

    Authors: Stephen D. Hall, Kenneth E. Thummel, Paul B. Watkins, Kenneth S. Lown, Leslie Z. Benet, Mary F. Paine, Robert R. Mayo, D. Kim Turgeon, David G. Bailey, Robert J. Fontana, Steven Wrighton - 1999 cited by 239

  16. Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide

    Authors: John R. Cashman, Sang B. Park, Ziping Yang, Steven Wrighton, Peyton Jacob, Neal L. Benowitz - Chemical Research in Toxicology 1992 cited by 213

  17. THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS*

    Authors: Steven Wrighton, Erin G. Schuetz, Kenneth E. Thummel, Danny D. Shen, Kenneth R. Korzekwa, Paul B. Watkins - Drug Metabolism Reviews 2000 cited by 211

  18. The human drug metabolizing cytochromes P450

    Authors: Steven Wrighton, Mark VandenBranden, Barbara J. Ring - Journal of Pharmacokinetics and Biopharmaceutics 1996 cited by 166

  19. The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2

    Authors: Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, E.J. Perkins, Steven Wrighton, Kenneth J. Ruterbories, Miho Kazui, Nagy A. Farid - Drug Metabolism and Disposition 2008 cited by 127

  20. The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism*†

    Authors: Michael B. Fisher, Mary F. Paine, Timothy J. Strelevitz, Steven Wrighton - Drug Metabolism Reviews 2001 cited by 371

  21. Selectivity of the Multidrug Resistance Modulator, LY335979, for P-Glycoprotein and Effect on Cytochrome P-450 Activities

    Authors: Anne H. Dantzig, Robert L. Shepard, K L Law, Linda B. Tabas, Susan E. Pratt, Jennifer S. Gillespie, S N Binkley, Michael T. Kuhfeld, James J. Starling, Steven Wrighton - Journal of Pharmacology and Experimental Therapeutics 1999 cited by 179

  22. Differential Modulation of UDP-Glucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3-glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes

    Authors: J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, Kristina Campanale, David Jones, Stephen D. Hall, Steven Wrighton - Drug Metabolism and Disposition 2002 cited by 152

  23. Effects of Antipsychotic Drugs on Ito, INa, Isus, IK1, and hERG: QT Prolongation, Structure Activity Relationship, and Network Analysis

    Authors: William Crumb, Sean Ekins, R. Dustan Sarazan, James H. Wikel, Steven Wrighton, Christopher Carlson, Charles M. Beasley - Pharmaceutical Research 2006 cited by 89

  24. Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human

    Authors: Eric T. Williams, James A. Bacon, David M. Bender, Jennifer J. Lowinger, Wenkai Guo, Mariam Ehsani, Xiliang Wang, He Wang, Yuewei Qian, Kenneth J. Ruterbories, Steven Wrighton, E.J. Perkins - Drug Metabolism and Disposition 2011 cited by 72