THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS*

Authors: Steven Wrighton, Erin G. Schuetz, Kenneth E. Thummel, Danny D. Shen, Kenneth R. Korzekwa, Paul B. Watkins - Drug Metabolism Reviews 2000 cited by 211

The CYP3A subfamily of cytochromes P450 (CYP) in humans is composed of CYP3A4, 3A5, and 3A7. The CYP3A forms are involved in the metabolism of an amazingly large number of structurally diverse xeno...