Klaus H. Kaestner
Active 1986–2025
- 234
- Papers
- 45,137
- Citations
- 125
- h-index
- 230
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology46.4%
- Medicine39.1%
- Immunology and Microbiology7%
- Neuroscience4.4%
- Nursing0.8%
- Agricultural and Biological Sciences0.7%
- Other1.6%
Topics
- Pancreatic function and diabetes5.8%
- Epigenetics and DNA Methylation3.1%
- Diabetes and associated disorders2.3%
- Metabolism, Diabetes, and Cancer2%
- FOXO transcription factor regulation1.8%
- Adipose Tissue and Metabolism1.7%
- Other83.3%
Coauthors
- Jonathan Schug40
- Ali Naji21
- Peter White16
- Chengyang Liu14
- Yue J. Wang14
- Catherine Lee May11
- Daniel Traum11
- Jonathan P. Katz11
- Benjamin Gläser10
- Nan Gao10
- Dana Avrahami9
- John Brestelli9
- Long Gao9
- Maria L. Golson9
- Alvin C. Powers8
- Catherine S. Lee8
- Franz M. Matschinsky8
- Geetu Tuteja8
- John Le Lay8
- Joshua R. Friedman8
- Linda E. Greenbaum8
- Mark A. Atkinson8
- Ashleigh Morgan7
- Craig Dorrell7
All papers
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
Authors: Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J. Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou, Brian C. Capell, Caiyue Xu, Mingang Xu, Julia E. Kieckhaefer, Tianying Jiang, Michal Shoshkes-Carmel, K. M. Ahasan Al Tanim, Glen N. Barber, John T. Seykora, Sarah E. Millar, Klaus H. Kaestner, Benjamin A. García, Peter D. Adams, Shelley L. Berger - Nature 2017 cited by 1,320
- Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis
Authors: Marijana Vujković, Jacob M. Keaton, Julie A. Lynch, Donald R. Miller, Jin Zhou, Catherine Tcheandjieu, Jennifer E. Huffman, Themistocles L. Assimes, Kimberly Lorenz, Xiang Zhu, Austin T. Hilliard, Renae Judy, Jie Huang, Kyung Min Lee, Derek Klarin, Saiju Pyarajan, John Danesh, Olle Melander, Asif Rasheed, Nadeem Hayat Mallick, Shahid Hameed, Irshad Hussain Qureshi, Muhammad Afzal, Uzma Malik, Anjum Jalal, Shahid Abbas, Xin Sheng, Long Gao, Klaus H. Kaestner, Katalin Suszták, Yan V. Sun, Scott L. DuVall, Kelly Cho, Jennifer S. Lee, J. Michael Gaziano, Lawrence S. Phillips, James B. Meigs, Peter D. Reaven, Peter W.F. Wilson, Todd L. Edwards, Daniel J. Rader, Scott M. Damrauer, Christopher J. O’Donnell, Philip S. Tsao, Mark A. Atkinson, Al C. Powers, Ali Naji, Klaus H. Kaestner, Gonçalo R. Abecasis, Aris Baras, Michael Cantor, Giovanni Coppola, Aris N. Economides, Luca A. Lotta, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Christina Beechert, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Michael Lattari, Alexander Lopez, Thomas D. Schleicher, Maria Sotiropoulos Padilla, Karina Toledo, Louis Widom, Sarah E. Wolf, Manasi Pradhan, Kia Manoochehri, Ricardo H. Ulloa, Xiaodong Bai, Suganthi Balasubramanian, Leland Barnard, Andrew Blumenfeld, Gisu Eom, Lukas Habegger, Alicia Hawes, Shareef Khalid, Evan K. Maxwell, William Salerno, Jeffrey Staples, Ashish Yadav, Marcus B. Jones, Lyndon J. Mitnaul, VA Million Veteran Program, Samuel M. Aguayo, Sunil K. Ahuja, Zuhair K. Ballas, Sujata Bhushan, Edward J. Boyko, David Cohen, John Concato, Joseph I. Constans, Louis J. Dell’Italia, Joseph Fayad, Ronald Fernando, Hermes Flórez, Melinda A. Gaddy, Saib Gappy and 82 more - Nature Genetics 2020 cited by 801
- β-Hydroxybutyrate suppresses colorectal cancer
Authors: Oxana Dmitrieva-Posocco, Andrea C. Wong, Patrick Lundgren, Aleksandra Golos, Hélène C. Descamps, Lenka Dohnalová, Zvi Cramer, Yuhua Tian, Brian Yueh, Onur Eskiocak, Gabor Egervári, Yemin Lan, Jinping Liu, Jiaxin Fan, Jihee Kim, Bhoomi Madhu, Kai Markus Schneider, Svetlana Khoziainova, Natalia Andreeva, Qiaohong Wang, Ning Li, Emma E. Furth, Will Bailis, Judith R. Kelsen, Kathryn E. Hamilton, Klaus H. Kaestner, Shelley L. Berger, Jonathan A. Epstein, Rajan Jain, Mingyao Li, Semir Beyaz, Christopher J. Lengner, Bryson W. Katona, Sergei I. Grivennikov, Christoph A. Thaiss, Maayan Levy - Nature 2022 cited by 313
- Krüppel-like factor 4 regulates macrophage polarization
Authors: Xudong Liao, Nikunj Sharma, Fehmida Kapadia, Guangjin Zhou, Yuan Lu, Hong Hong, Kaavya Paruchuri, Ganapati H. Mahabeleshwar, Élise Dalmas, Nicolas Venteclef, Chris A. Flask, Julian Kim, Bryan Doreian, Kurt Q. Lu, Klaus H. Kaestner, Anne Hamik, Karine Clément, Mukesh K. Jain - Journal of Clinical Investigation 2011 cited by 761
- Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
Authors: Zhen Miao, Michael S. Balzer, Ziyuan Ma, Hongbo Liu, Junnan Wu, Rojesh Shrestha, Tamás Arányi, Amy Kwan, Ayano Kondo, Marco Pontoglio, Junhyong Kim, Mingyao Li, Klaus H. Kaestner, Katalin Suszták - Nature Communications 2021 cited by 224
- Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression
Authors: Amin Abedini, Jonathan Levinsohn, Konstantin A. Klötzer, Bernhard Dumoulin, Ziyuan Ma, Julia Frederick, Poonam Dhillon, Michael S. Balzer, Rojesh Shrestha, Hongbo Liu, Steven Vitale, Andi M. Bergeson, Kishor Devalaraja‐Narashimha, Paola Grandi, Tanmoy Bhattacharyya, Erding Hu, Steven S. Pullen, Carine M. Boustany‐Kari, Paolo Guarnieri, Anil Karihaloo, Daniel Traum, Hanying Yan, Kyle Coleman, Matthew Palmer, Lea Sarov‐Blat, Lori Morton, Christopher A. Hunter, Klaus H. Kaestner, Mingyao Li, Katalin Suszták - Nature Genetics 2024 cited by 148
- Subepithelial telocytes are an important source of Wnts that supports intestinal crypts
Authors: Michal Shoshkes-Carmel, Yue J. Wang, Kirk J. Wangensteen, Beáta Tóth, Ayano Kondo, Efi E. Massasa, Shalev Itzkovitz, Klaus H. Kaestner - Nature 2018 cited by 523
- Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes
Authors: Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, Aanchal Mongia, Maria L. Golson, Yue J. Wang, Ashleigh Morgan, Chengyang Liu, Jonathan Schug, Jinping Liu, Minghui Wu, Daniel Traum, Ayano Kondo, Catherine Lee May, Naomi Goldman, Wenliang Wang, Michael D. Feldman, Jason H. Moore, Alberto Sada Japp, Michael R. Betts, Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, Aanchal Mongia, Maria L. Golson, Yue J. Wang, Ashleigh Morgan, Chengyang Liu, Jonathan Schug, Jinping Liu, Minghui Wu, Daniel Traum, Ayano Kondo, Catherine Lee May, Naomi Goldman, Wenliang Wang, Michael D. Feldman, Jason H. Moore, Alberto Sada Japp, Michael R. Betts, Robert B. Faryabi, Ali Naji, Klaus H. Kaestner, Golnaz Vahedi, Robert B. Faryabi, Ali Naji, Klaus H. Kaestner, Golnaz Vahedi - Nature Metabolism 2022 cited by 201
- Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy
Authors: Rajasekharan Somasundaram, Thomas Connelly, Robin Choi, Hyeree Choi, Anastasia Samarkina, Ling Li, Elizabeth Gregorio, Yeqing Chen, Rohit Thakur, Mohamed Abdel‐Mohsen, Marilda Beqiri, Meaghan Kiernan, Michela Perego, Fang Wang, Min Xiao, Patricia Brafford, Xue Yang, Xiaowei Xu, Anthony Secreto, Gwenn Danet-Desnoyers, Daniel Traum, Klaus H. Kaestner, Alexander C. Huang, Denitsa M. Hristova, Joshua X. Wang, Mizuho Fukunaga‐Kalabis, Clemens Krepler, Fang Ping-Chen, Xiangyang Zhou, Alexis Gutierrez, Vito W. Rebecca, Prashanthi Vonteddu, Farokh Dotiwala, Shashi Bala, Sonali Majumdar, Harsh Dweep, Jayamanna Wickramasinghe, Andrew V. Kossenkov, Jorge Reyes-Arbujas, Kenisha Santiago, Tran B. Nguyen, Johannes Griss, Frederick Keeney, James E. Hayden, Brian Gavin, David B. Weiner, Luis J. Montaner, Qin Liu, Lukas Peiffer, Jürgen C. Becker, Elizabeth M. Burton, Michael A. Davies, Michael T. Tetzlaff, Kar Muthumani, Jennifer A. Wargo, Dmitry I. Gabrilovich, Meenhard Herlyn - Nature Communications 2021 cited by 184
- Single-Cell Transcriptomics of the Human Endocrine Pancreas
Authors: Yue J. Wang, Jonathan Schug, Kyoung‐Jae Won, Chengyang Liu, Ali Naji, Dana Avrahami, Maria L. Golson, Klaus H. Kaestner - Diabetes 2016 cited by 480
- NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)
Authors: Klaus H. Kaestner, Alvin C. Powers, Ali Naji, Mark A. Atkinson - Diabetes 2019 cited by 179
- Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
Authors: Han Cho, James Mu, Jason K. Kim, Joanne L. Thorvaldsen, Qingwei Chu, E. Bryan Crenshaw, Klaus H. Kaestner, Marisa S. Bartolomei, Gerald I. Shulman, Morris J. Birnbaum - Science 2001 cited by 1,835
- The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation
Authors: Makiko Iwafuchi, Greg Donahue, Akshay Kakumanu, Jason A. Watts, Shaun Mahony, B. Franklin Pugh, Dolim Lee, Klaus H. Kaestner, Kenneth S. Zaret - Molecular Cell 2016 cited by 409
- DANPOS: Dynamic analysis of nucleosome position and occupancy by sequencing
Authors: Kaifu Chen, Yuanxin Xi, Xuewen Pan, Zhaoyu Li, Klaus H. Kaestner, Jessica K. Tyler, Sharon Dent, Xiangwei He, Wei Li - Genome Research 2012 cited by 435
- Human islets contain four distinct subtypes of β cells
Authors: Craig Dorrell, Jonathan Schug, Pamela Canaday, Holger A. Russ, Branden Tarlow, Maria T. Grompe, Tamara Horton, Matthias Hebrok, Philip R. Streeter, Klaus H. Kaestner, Markus Grompe - Nature Communications 2016 cited by 382
- KLF Family Members Regulate Intrinsic Axon Regeneration Ability
Authors: Darcie L. Moore, Murray G. Blackmore, Ying Hu, Klaus H. Kaestner, John L. Bixby, Vance Lemmon, Jeffrey L. Goldberg - Science 2009 cited by 724
- Fox transcription factors: from development to disease
Authors: Maria L. Golson, Klaus H. Kaestner - Development 2016 cited by 423
- CREB pathway links PGE2 signaling with macrophage polarization
Authors: Bing Luan, Young‐Sil Yoon, John Le Lay, Klaus H. Kaestner, Susan Hedrick, Marc Montminy - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 276
- Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes
Authors: Yue J. Wang, Daniel Traum, Jonathan Schug, Long Gao, Chengyang Liu, Mark A. Atkinson, Alvin C. Powers, Michael D. Feldman, Ali Naji, Kyong‐Mi Chang, Klaus H. Kaestner - Cell Metabolism 2019 cited by 234
- Adaptation to chronic ER stress enforces pancreatic β-cell plasticity
Authors: Chien-Wen Chen, Bo‐Jhih Guan, Mohammed R. Alzahrani, Zhaofeng Gao, Long Gao, Syrena Bracey, Jing Wu, Cheikh A. Mbow, Raul Jobava, Leena Haataja, Ajay Zalavadia, Ashleigh E. Schaffer, Hugo Lee, Thomas LaFramboise, Ilya Bederman, Peter Arvan, Clayton E. Mathews, Ivan Gerling, Klaus H. Kaestner, Boaz Tirosh, Feyza Engin, Maria Hatzoglou - Nature Communications 2022 cited by 102
- Organisation of the human pancreas in health and in diabetes
Authors: Mark A. Atkinson, Martha Campbell‐Thompson, Irina Kusmartseva, Klaus H. Kaestner - Diabetologia 2020 cited by 129
- Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data
Authors: Michelle Y. Y. Lee, Klaus H. Kaestner, Mingyao Li - Genome biology 2023 cited by 58
- Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling
Authors: Nofar Rosenberg, Matthias Van Haele, Tali Lanton, Neta Brashi, Zohar Bromberg, Hanan Adler, Hilla Giladi, Amnon Peled, Daniel Goldenberg, Jonathan H. Axelrod, Alina Simerzin, Chofit Chai, Mor Paldor, Aurelia Markezana, Dayana Yaish, Zohar Shemulian, Dvora Gross, Shanny Barnoy, Maytal Gefen, Osher Amran, Sofie Claerhout, Mirian Fernández-Vaquero, María García‐Beccaria, Danijela Heide, Michal Shoshkes-Carmel, Dirk Schmidt‐Arras, Sharona Elgavish, Yuval Nevo, Hadar Benyamini, Janina E. E. Tirnitz‐Parker, Aranzazu Sánchez, Blanca Herrera, Rifaat Safadi, Klaus H. Kaestner, Stefan Rose‐John, Tania Roskams, Mathias Heikenwälder, Eithan Galun - Journal of Hepatology 2022 cited by 70
- Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer
Authors: Zhaoyu Li, Geetu Tuteja, Jonathan Schug, Klaus H. Kaestner - Cell 2012 cited by 391
