Paul A. Marks
Active 1955–2013
- Also published as
- PAUL A. MARKS
- 82
- Papers
- 24,812
- Citations
- 81
- h-index
- 82
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology65%
- Medicine23.9%
- Neuroscience4.8%
- Immunology and Microbiology2.6%
- Chemistry1%
- Agricultural and Biological Sciences0.9%
- Other1.8%
Topics
- Histone Deacetylase Inhibitors Research17.2%
- Protein Degradation and Inhibitors7.2%
- Epigenetics and DNA Methylation6.8%
- Peptidase Inhibition and Analysis3.8%
- Ubiquitin and proteasome pathways2.6%
- Autophagy in Disease and Therapy1.8%
- Other60.6%
Coauthors
- Richard A. Rifkind27
- Victoria M. Richon27
- Ronald Breslow7
- Lang Ngo6
- William Kevin Kelly6
- Xianbo Zhou6
- Howard I. Scher5
- Milos Dokmanovic5
- Gisela Perez4
- Judy H. Chiao4
- Lawrence B. Schwartz4
- Owen A. O’Connor4
- Weisheng Xu4
- Arthur Bank3
- Ciaran J. McMullan3
- Constantine S. Mitsiades3
- Donna L. Smith3
- Gillian P. Bates3
- M Sheffery3
- Megan L. Choy3
- Nicholas Mitsiades3
- Stacie Richardson3
- Thomas A. Miller3
- Toby Johnson3
All papers
- Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug
Authors: Paul A. Marks, Ronald Breslow - Nature Biotechnology 2007 cited by 1,201
- Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
Authors: Michael S. Finnin, Jill R. Donigian, Alona Cohen, Victoria M. Richon, Richard A. Rifkind, Paul A. Marks, Ronald Breslow, Nikola P. Pavletich - Nature 1999 cited by 1,701
- Histone deacetylases and cancer: causes and therapies
Authors: Paul A. Marks, Richard A. Rifkind, Victoria M. Richon, Ronald Breslow, Thomas A. Miller, William Kevin Kelly - Nature reviews. Cancer 2001 cited by 1,856
- Histone Deacetylase Inhibitors: Overview and Perspectives
Authors: Milos Dokmanovic, Cathy Clarke, Paul A. Marks - Molecular Cancer Research 2007 cited by 1,158
- Apoptotic and autophagic cell death induced by histone deacetylase inhibitors
Authors: Yufang Shao, Zhonghua Gao, Paul A. Marks, Xuejun Jiang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 604
- Histone deacetylase inhibitor selectively induces p21 WAF1 expression and gene-associated histone acetylation
Authors: Victoria M. Richon, Todd W. Sandhoff, Richard A. Rifkind, Paul A. Marks - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 1,097
- HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration
Authors: Michał Mielcarek, Christian Landles, Andreas Weiss, Amyaouch Bradaïa, Tamara Seredenina, Linda Inuabasi, Georgina F Osborne, Kristian Wadel, Chrystelle Touller, Rachel Butler, Janette Robertson, Sophie Franklin, Donna L. Smith, Larry Park, Paul A. Marks, Erich E. Wanker, Eric N. Olson, Ruth Luthi‐Carter, Herman van der Putten, Vahri Beaumont, Gillian P. Bates - PLoS Biology 2013 cited by 170
- A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
Authors: Victoria M. Richon, Stéphane Emiliani, Eric Verdin, Yael Webb, Ronald Breslow, Richard A. Rifkind, Paul A. Marks - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 914
- Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors
Authors: Melissa J. Peart, Gordon K. Smyth, Ryan K. van Laar, David D.L. Bowtell, Victoria M. Richon, Paul A. Marks, Andrew J. Holloway, Ricky W. Johnstone - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 543
- Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair
Authors: J.-H. Lee, Megan L. Choy, Lang Ngo, Steven S. Foster, Paul A. Marks - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 378
- Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer
Authors: William Kevin Kelly, Owen A. O’Connor, Lee M. Krug, Judy H. Chiao, Mark Heaney, Tracy Curley, Barbara MacGregore-Cortelli, William P. Tong, J. Paul Secrist, Lawrence B. Schwartz, Stacy Richardson, Elaina Chu, Semra Olgac, Paul A. Marks, Howard I. Scher, Victoria M. Richon - Journal of Clinical Oncology 2005 cited by 907
- The clinical development of histone deacetylase inhibitors as targeted anticancer drugs
Authors: Paul A. Marks - Expert Opinion on Investigational Drugs 2010 cited by 280
- Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
Authors: Emma Hockly, Victoria M. Richon, Benjamin Woodman, Donna L. Smith, Xianbo Zhou, Eddie Rosa, Kirupa Sathasivam, Shabnam Ghazi‐Noori, Amarbirpal Mahal, Philip A. S. Lowden, Joan S. Steffan, Joan Marsh, Leslie M. Thompson, Cathryn M. Lewis, Paul A. Marks, Gillian P. Bates - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 841
- Cloning and characterization of a histone deacetylase, HDAC9
Authors: Xianbo Zhou, Paul A. Marks, Richard A. Rifkind, Victoria M. Richon - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 242
- Mechanisms of Resistance to Histone Deacetylase Inhibitors
Authors: Ju‐Hee Lee, Megan L. Choy, Paul A. Marks - Advances in cancer research 2012 cited by 101
- The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin
Authors: Lisa M. Butler, Xianbo Zhou, Weisheng Xu, Howard I. Scher, Richard A. Rifkind, Paul A. Marks, Victoria M. Richon - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 cited by 508
- Clinical Experience With Intravenous and Oral Formulations of the Novel Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid in Patients With Advanced Hematologic Malignancies
Authors: Owen A. O’Connor, Mark Heaney, Lawrence B. Schwartz, Stacie Richardson, Robert D. Willim, Barbara MacGregor‐Cortelli, Tracey Curly, Craig H. Moskowitz, Carol S. Portlock, Steven M. Horwitz, Andrew D. Zelenetz, Stanley Frankel, Victoria M. Richon, Paul A. Marks, William Kevin Kelly - Journal of Clinical Oncology 2005 cited by 403
- Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death
Authors: Noor Gammoh, Du Lam, Cindy Puente, Ian G. Ganley, Paul A. Marks, Xuejun Jiang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 210
- Histone deacetylase inhibitors: A chemical genetics approach to understanding cellular functions
Authors: Paul A. Marks - Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2010 cited by 189
- SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease
Authors: Michał Mielcarek, Caroline Benn, Sophie Franklin, Donna L. Smith, Ben Woodman, Paul A. Marks, Gillian P. Bates - PLoS ONE 2011 cited by 162
- Modulation of Renal Disease in MRL/lpr Mice by Suberoylanilide Hydroxamic Acid
Authors: Christopher M. Reilly, Nilamadhab Mishra, Julie M. Miller, Dimple Joshi, Phillip Ruiz, Victoria M. Richon, Paul A. Marks, Gary S. Gilkeson - The Journal of Immunology 2004 cited by 146
- Development of a histone deacetylase 6 inhibitor and its biological effects
Authors: Ju‐Hee Lee, Adaickapillai Mahendran, Yuanshan Yao, Lang Ngo, Gisela Venta-Perez, Megan L. Choy, Nathaniel Kim, Won Seok Ham, Ronald Breslow, Paul A. Marks - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 132
- Prospects: Histone deacetylase inhibitors
Authors: Milos Dokmanovic, Paul A. Marks - Journal of Cellular Biochemistry 2005 cited by 479
- The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells.
Authors: Pamela N. Münster, Tiffany A. Troso-Sandoval, Neal Rosen, Richard A. Rifkind, Paul A. Marks, Victoria M. Richon - 2001 cited by 374
