Peter A. Edwards
Active 1968–2021
- 96
- Papers
- 26,390
- Citations
- 86
- h-index
- 96
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine52%
- Biochemistry, Genetics and Molecular Biology30.6%
- Immunology and Microbiology9.2%
- Neuroscience1.8%
- Pharmacology, Toxicology and Pharmaceutics1.7%
- Agricultural and Biological Sciences1.5%
- Other3.2%
Topics
- Cholesterol and Lipid Metabolism7.7%
- Drug Transport and Resistance Mechanisms7%
- Peroxisome Proliferator-Activated Receptors4.3%
- Gut microbiota and health3.7%
- Liver Disease Diagnosis and Treatment3.5%
- Atherosclerosis and Cardiovascular Diseases2.4%
- Other71.4%
Coauthors
- Alan M. Fogelman20
- Yanqiao Zhang13
- Ángel Baldán10
- Peter Tontonoz9
- Elizabeth J. Tarling8
- Heidi R. Kast-Woelbern8
- Paul T. Tarr8
- Thomas Q. de Aguiar Vallim8
- Aldons J. Lusis7
- Johan Ericsson7
- M E Haberland7
- Brian J. Van Lenten6
- Joy S. Frank6
- Andrew M. Anisfeld5
- Bryan Laffitte5
- Frank J. Gonzalez5
- J Seager5
- Martha Hokom5
- Puiying A. Mak5
- Simon Jackson5
- Timothy M. Willson5
- A M Fogelman4
- Hans C. Lee4
- Matthew A. Kennedy4
All papers
- Pleiotropic Roles of Bile Acids in Metabolism
Authors: Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling, Peter A. Edwards - Cell Metabolism 2013 cited by 1,190
- FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption
Authors: Bethan L. Clifford, Leslie R. Sedgeman, Kevin J. Williams, Pauline Morand, Angela Cheng, Kelsey E. Jarrett, Alvin P. Chan, Madelaine C. Brearley-Sholto, Annika Wahlström, Julianne W. Ashby, William D. Barshop, James A. Wohlschlegel, Anna C. Calkin, Yingying Liu, Anders Thorell, Peter J. Meikle, Brian G. Drew, Julia J. Mack, Hanns–Ulrich Marschall, Elizabeth J. Tarling, Peter A. Edwards, Thomas Q. de Aguiar Vallim - Cell Metabolism 2021 cited by 455
- Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation
Authors: Brian J. Bennett, Thomas Q. de Aguiar Vallim, Zeneng Wang, Diana M. Shih, Yonghong Meng, Jill C. Gregory, Hooman Allayee, Richard Lee, Mark J. Graham, Rosanne M. Crooke, Peter A. Edwards, Stanley L. Hazen, Aldons J. Lusis - Cell Metabolism 2013 cited by 1,058
- LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response
Authors: Steven J. Bensinger, Michelle N. Bradley, Sean B. Joseph, Noam Zelcer, Edith M. Janssen, Mary Ann Hausner, Roger Shih, John S. Parks, Peter A. Edwards, Beth D. Jamieson, Peter Tontonoz - Cell 2008 cited by 726
- Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR
Authors: Noelia A-González, Steven J. Bensinger, Cynthia Hong, Susana Beceiro, Michelle N. Bradley, Noam Zelcer, José Manuel Deniz, Cristina M. Ramírez, Mercedes Díaz, Germán Gallardo, Carlos Ruiz de Galarreta, Jon Salazar, Félix López, Peter A. Edwards, John S. Parks, Miguel Andújar, Peter Tontonoz, Antonio Castrillo - Immunity 2009 cited by 668
- Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
Authors: Yanqiao Zhang, Florence Ying Lee, Gabriel Barrera, Hans C. Lee, Charisse Vales, Frank J. Gonzalez, Timothy M. Willson, Peter A. Edwards - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 937
- A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis
Authors: Ajay Chawla, William A. Boisvert, Chih‐Hao Lee, Bryan Laffitte, Yaacov Barak, Sean B. Joseph, Debbie Liao, László Nagy, Peter A. Edwards, Linda K. Curtiss, Ronald M. Evans, Peter Tontonoz - Molecular Cell 2001 cited by 1,339
- LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition
Authors: Xin Rong, Carolyn J. Albert, Cynthia Hong, Mark A. Duerr, Brian T. Chamberlain, Elizabeth J. Tarling, Ayaka Ito, Jie Gao, Bo Wang, Peter A. Edwards, Michael E. Jung, David A. Ford, Peter Tontonoz - Cell Metabolism 2013 cited by 318
- ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation
Authors: Matthew A. Kennedy, Gabriel Barrera, Kotoka Nakamura, Ángel Baldán, Paul T. Tarr, Michael C. Fishbein, Joy S. Frank, Omar L. Francone, Peter A. Edwards - Cell Metabolism 2005 cited by 874
- Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration
Authors: Abdoulaye Sène, Aslam A. Khan, Douglas N. Cox, Rei Nakamura, Andrea Santeford, B. M. Kim, Rohini Sidhu, Michael D. Onken, J. William Harbour, Shira Hagbi-Levi, Itay Chowers, Peter A. Edwards, Ángel Baldán, John S. Parks, Daniel S. Ory, Rajendra S. Apte - Cell Metabolism 2013 cited by 277
- Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα
Authors: Asha Venkateswaran, Bryan Laffitte, Sean B. Joseph, Puiying A. Mak, Damien C. Wilpitz, Peter A. Edwards, Peter Tontonoz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 999
- Role of ABC transporters in lipid transport and human disease
Authors: Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim, Peter A. Edwards - Trends in Endocrinology and Metabolism 2013 cited by 298
- ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter
Authors: Elizabeth J. Tarling, Peter A. Edwards - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 222
- Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor
Authors: Heidi R. Kast-Woelbern, Bryan Goodwin, Paul T. Tarr, Stacey A. Jones, Andrew M. Anisfeld, Catherine M. Stoltz, Peter Tontonoz, S. A. Kliewer, Timothy M. Willson, Peter A. Edwards - Journal of Biological Chemistry 2002 cited by 908
- A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR
Authors: Michael Downes, Mark A. Verdecia, Anthony J. Roecker, Robert Hughes, John B. Hogenesch, Heidi R. Kast-Woelbern, M.E. Bowman, Jean-Luc Ferrer, Andrew M. Anisfeld, Peter A. Edwards, John M. Rosenfeld, Jacqueline G. Alvarez, Joseph P. Noel, K. C. Nicolaou, Ronald M. Evans - Molecular Cell 2003 cited by 386
- FXR, a multipurpose nuclear receptor
Authors: Florence Y. Lee, Hans C. Lee, Melissa L. Hubbert, Peter A. Edwards, Yanqiao Zhang - Trends in Biochemical Sciences 2006 cited by 334
- Atherosclerosis: Basic Mechanisms
Authors: Judith A. Berliner, Mohamad Navab, Alan M. Fogelman, Joy S. Frank, Linda L. Demer, Peter A. Edwards, Andrew D. Watson, Aldons J. Lusis - Circulation 1995 cited by 1,694
- A role for the apoptosis inhibitory factor AIM/Spα/Api6 in atherosclerosis development
Authors: Satoko Arai, John M. Shelton, Mingyi Chen, Michelle N. Bradley, Antonio Castrillo, Angie L. Bookout, Puiying A. Mak, Peter A. Edwards, David J. Mangelsdorf, Peter Tontonoz, Toru Miyazaki - Cell Metabolism 2005 cited by 293
- Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) regulates triglyceride metabolism by activation of the nuclear receptor FXR
Authors: Yanqiao Zhang, Lawrence W. Castellani, Christopher J. Sinal, Frank J. Gonzalez, Peter A. Edwards - Genes & Development 2004 cited by 361
- Natural Structural Variants of the Nuclear Receptor Farnesoid X Receptor Affect Transcriptional Activation
Authors: Yanqiao Zhang, Heidi R. Kast-Woelbern, Peter A. Edwards - Journal of Biological Chemistry 2002 cited by 277
- Sterols and Isoprenoids: Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway
Authors: Peter A. Edwards, Johan Ericsson - Annual Review of Biochemistry 1999 cited by 463
- Farnesoid X-Activated Receptor Induces Apolipoprotein C-II Transcription: a Molecular Mechanism Linking Plasma Triglyceride Levels to Bile Acids
Authors: Heidi R. Kast-Woelbern, Catherine Nguyen, Christopher J. Sinal, Stacey A. Jones, Bryan Laffitte, Karen Reue, Frank J. Gonzalez, Timothy M. Willson, Peter A. Edwards - Molecular Endocrinology 2001 cited by 330
- Hepatic Hepatocyte Nuclear Factor 4α Is Essential for Maintaining Triglyceride and Cholesterol Homeostasis
Authors: Liya Yin, Huiyan Ma, Xuemei Ge, Peter A. Edwards, Yanqiao Zhang - Arteriosclerosis Thrombosis and Vascular Biology 2010 cited by 149
- FXR regulates organic solute transporters α and β in the adrenal gland, kidney, and intestine
Authors: Hans C. Lee, Yanqiao Zhang, Florence Y. Lee, Stanley F. Nelson, Frank J. Gonzalez, Peter A. Edwards - Journal of Lipid Research 2005 cited by 174
