Stefani Spranger
Active 2009–2026
- 65
- Papers
- 18,584
- Citations
- 48
- h-index
- 62
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine47.4%
- Immunology and Microbiology28.3%
- Biochemistry, Genetics and Molecular Biology18.3%
- Neuroscience2.6%
- Engineering2.2%
- Materials Science0.3%
- Other0.9%
Topics
- Cancer Immunotherapy and Biomarkers15.1%
- Immunotherapy and Immune Responses10%
- Immune Cell Function and Interaction6.1%
- CAR-T cell therapy research5.3%
- Immune cells in cancer4.8%
- interferon and immune responses3.8%
- Other54.9%
Coauthors
- Thomas F. Gajewski22
- Brendan Horton12
- Maria Zagorulya8
- K. Dane Wittrup7
- Darrell J. Irvine6
- Jason J. Luke5
- Kim B. Nguyen5
- Leticia Corrales5
- Noor Momin5
- Riyue Bao5
- Yuanyuan Zha5
- Dolores J. Schendel4
- Ellen Duong4
- Emi A. Lutz4
- Forest M. White4
- Leon Yim4
- Malte Roerden4
- Paolo A. Ascierto4
- Vidit Bhandarkar4
- Allison Sheen3
- Bernhard Frankenberger3
- Duncan M. Morgan3
- Elen Torres-Mejia3
- J. Christopher Love3
All papers
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
Authors: Seng‐Ryong Woo, Mercedes B. Fuertes, Leticia Corrales, Stefani Spranger, Michael J. Furdyna, Michael Y.K. Leung, Ryan Duggan, Ying Wang, Glen N. Barber, Katherine A. Fitzgerald, Maria-Luisa Alegre, Thomas F. Gajewski - Immunity 2014 cited by 1,834
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
Authors: Stefani Spranger, Riyue Bao, Thomas F. Gajewski - Nature 2015 cited by 2,840
- Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy
Authors: Stefani Spranger, Daisy Dai, Brendan Horton, Thomas F. Gajewski - Cancer Cell 2017 cited by 1,410
- Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy
Authors: Weiyi Peng, Jie Qing Chen, Chengwen Liu, Shruti Malu, Caitlin Creasy, Michael T. Tetzlaff, Chunyu Xu, Jodi A. McKenzie, Chunlei Zhang, Xiaoxuan Liang, Leila J. Williams, Wanleng Deng, Guo Chen, Rina M. Mbofung, Alexander J. Lazar, Carlos A. Torres‐Cabala, Zachary A. Cooper, Pei-Ling Chen, Trang N. Tieu, Stefani Spranger, Xiaoxing Yu, Chantale Bernatchez, Marie‐Andrée Forget, Cara Haymaker, Rodabe N. Amaria, Jennifer L. McQuade, Isabella C. Glitza, Tina Cascone, Haiyan S. Li, Lawrence N. Kwong, Timothy P. Heffernan, Jianhua Hu, Roland L. Bassett, Marcus Bosenberg, Scott E. Woodman, Willem W. Overwijk, Gregory Lizée, Jason Roszik, Thomas F. Gajewski, Jennifer A. Wargo, Jeffrey E. Gershenwald, Laszlo Radvanyi, Michael A. Davies, Patrick Hwu - Cancer Discovery 2015 cited by 1,531
- Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity
Authors: Ellen Duong, Tim Fessenden, Emi A. Lutz, Teresa Dinter, Leon Yim, Sarah E. Blatt, Arjun Bhutkar, K. Dane Wittrup, Stefani Spranger - Immunity 2021 cited by 356
- Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells
Authors: Stefani Spranger, Robbert M. Spaapen, Yuanyuan Zha, Jason B. Williams, Yuru Meng, Thanh T. Ha, Thomas F. Gajewski - Science Translational Medicine 2013 cited by 1,674
- WNT/β-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers
Authors: Jason J. Luke, Riyue Bao, Randy F. Sweis, Stefani Spranger, Thomas F. Gajewski - Clinical Cancer Research 2019 cited by 692
- Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer
Authors: Maria Zagorulya, Leon Yim, Duncan M. Morgan, Austin Edwards, Elen Torres-Mejia, Noor Momin, Chloe V. McCreery, Izabella Zamora, Brendan Horton, James G. Fox, K. Dane Wittrup, J. Christopher Love, Stefani Spranger - Immunity 2023 cited by 148
- Impact of oncogenic pathways on evasion of antitumour immune responses
Authors: Stefani Spranger, Thomas F. Gajewski - Nature reviews. Cancer 2018 cited by 658
- Innate immune signaling and regulation in cancer immunotherapy
Authors: Leticia Corrales, Vyara Matson, Blake Flood, Stefani Spranger, Thomas F. Gajewski - Cell Research 2016 cited by 421
- Lack of CD8 + T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer
Authors: Brendan Horton, Duncan M. Morgan, Noor Momin, Maria Zagorulya, Elen Torres-Mejia, Vidit Bhandarkar, K. Dane Wittrup, J. Christopher Love, Stefani Spranger - Science Immunology 2021 cited by 129
- Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy
Authors: Noor Momin, Naveen K. Mehta, Nitasha R. Bennett, Leyuan Ma, Joseph R. Palmeri, Magnolia M. Chinn, Emi A. Lutz, Byong H. Kang, Darrell J. Irvine, Stefani Spranger, K. Dane Wittrup - Science Translational Medicine 2019 cited by 208
- Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment
Authors: Stefani Spranger, Holly K. Koblish, Brendan Horton, Peggy Scherle, Robert Newton, Thomas F. Gajewski - Journal for ImmunoTherapy of Cancer 2014 cited by 545
- Deciphering the immunopeptidome in vivo reveals new tumour antigens
Authors: Alex M. Jaeger, Lauren Stopfer, Ryuhjin Ahn, Emma A. Sanders, Demi Sandel, William A. Freed-Pastor, William M. Rideout, Santiago Naranjo, Tim Fessenden, Kim B. Nguyen, Peter Winter, Ryan Kohn, Peter M.K. Westcott, Jason M. Schenkel, Sean-Luc Shanahan, Alex K. Shalek, Stefani Spranger, Forest M. White, Tyler Jacks - Nature 2022 cited by 104
- Cancer immune evasion, immunoediting and intratumour heterogeneity
Authors: Malte Roerden, Stefani Spranger - Nature reviews. Immunology 2025 cited by 185
- Direct and Indirect Regulators of Epithelial–Mesenchymal Transition–Mediated Immunosuppression in Breast Carcinomas
Authors: Anushka Dongre, Mohammad Rashidian, Elinor Ng Eaton, Ferenc Reinhardt, Prathapan Thiru, Maria Zagorulya, Sunita Nepal, Tuba Banaz, Anna Martner, Stefani Spranger, Robert A. Weinberg - Cancer Discovery 2020 cited by 142
- Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy
Authors: Lijie Zhai, Stefani Spranger, David C. Binder, Galina Gritsina, Kristen L. Lauing, Francis J. Giles, Derek A. Wainwright - Clinical Cancer Research 2015 cited by 324
- WNT Signaling in Cancer Immunosurveillance
Authors: Lorenzo Galluzzi, Stefani Spranger, Elaine Fuchs, Alejandro López‐Soto - Trends in Cell Biology 2018 cited by 243
- Density of immunogenic antigens does not explain the presence or absence of the T-cell–inflamed tumor microenvironment in melanoma
Authors: Stefani Spranger, Jason J. Luke, Riyue Bao, Yuanyuan Zha, Kyle M. Hernandez, Li Yan, Alexander P. Gajewski, Jorge Andrade, Thomas F. Gajewski - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 413
- Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation
Authors: Sachin Bhagchandani, Farrukh Vohidov, Lauren E. Milling, Yuzhou Evelyn Tong, Christopher M. Brown, Michelle L. Ramseier, Bin Liu, Timothy Fessenden, Hung V.‐T. Nguyen, Gavin R. Kiel, Lori Won, Róbert Langer, Stefani Spranger, Alex K. Shalek, Darrell J. Irvine, Jeremiah A. Johnson - Science Advances 2023 cited by 56
- Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment
Authors: Thomas F. Gajewski, Seng‐Ryong Woo, Yuanyuan Zha, Robbert M. Spaapen, Yan Zheng, Leticia Corrales, Stefani Spranger - Current Opinion in Immunology 2013 cited by 429
- A prime editor mouse to model a broad spectrum of somatic mutations in vivo
Authors: Zackery A. Ely, Nicolas Mathey‐Andrews, Santiago Naranjo, Samuel I. Gould, Kim L. Mercer, Gregory A. Newby, Christina M. Cabana, William M. Rideout, Grissel Cervantes-Jaramillo, Jennifer Khirallah, Katie Holland, Peyton B. Randolph, William A. Freed-Pastor, Jessie R. Davis, Zachary Kulstad, Peter M.K. Westcott, Lin Lin, Andrew V. Anzalone, Brendan Horton, Nimisha B. Pattada, Sean-Luc Shanahan, Zhongfeng Ye, Stefani Spranger, Qiaobing Xu, Francisco J. Sánchez‐Rivera, David R. Liu, Tyler Jacks - Nature Biotechnology 2023 cited by 58
- Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies
Authors: Brianna M. Lax, Joseph R. Palmeri, Emi A. Lutz, Allison Sheen, Jordan A. Stinson, Lauren Duhamel, Luciano Santollani, Alan Kennedy, Adrienne M. Rothschilds, Stefani Spranger, David M. Sansom, K. Dane Wittrup - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 53
- Mechanisms of tumor escape in the context of the T-cell-inflamed and the non-T-cell-inflamed tumor microenvironment
Authors: Stefani Spranger - International Immunology 2016 cited by 297
