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Stuart H. Orkin

Active 1975–2025

392
Papers
111,137
Citations
190
h-index
390
i10-index

Citations

Citations per year for Stuart H. Orkin1955: 2 citations1975: 2 citations1976: 6 citations1977: 5 citations1978: 7 citations1979: 14 citations1980: 55 citations1981: 43 citations1982: 60 citations1983: 96 citations1984: 156 citations1985: 136 citations1986: 150 citations1987: 225 citations1988: 246 citations1989: 247 citations1990: 294 citations1991: 416 citations1992: 382 citations1993: 464 citations1994: 415 citations1995: 591 citations1996: 530 citations1997: 703 citations1998: 702 citations1999: 702 citations2000: 704 citations2001: 619 citations2002: 898 citations2003: 952 citations2004: 804 citations2005: 1,041 citations2006: 776 citations2007: 789 citations2008: 977 citations2009: 976 citations2010: 1,051 citations2011: 1,244 citations2012: 1,120 citations2013: 1,168 citations2014: 1,000 citations2015: 1,053 citations2016: 1,101 citations2017: 1,107 citations2018: 1,003 citations2019: 2,724 citations2020: 2,844 citations2021: 2,660 citations2022: 1,892 citations2023: 1,441 citations2024: 2,007 citations2025: 790 citations2026: 24 citations1956–1974: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 14,516 citing papers, 37.7% of this breakdownChina: 3,256 citing papers, 8.5% of this breakdownUnited Kingdom: 2,843 citing papers, 7.4% of this breakdownGermany: 2,127 citing papers, 5.5% of this breakdownJapan: 1,601 citing papers, 4.2% of this breakdownFrance: 1,452 citing papers, 3.8% of this breakdownCanada: 1,395 citing papers, 3.6% of this breakdownItaly: 1,126 citing papers, 2.9% of this breakdownNetherlands: 941 citing papers, 2.4% of this breakdownAustralia: 898 citing papers, 2.3% of this breakdownSpain: 744 citing papers, 1.9% of this breakdownSwitzerland: 702 citing papers, 1.8% of this breakdown
0%37.7%Other 18%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology58.4%
  • Medicine29.3%
  • Immunology and Microbiology7.3%
  • Neuroscience2.5%
  • Agricultural and Biological Sciences0.8%
  • Engineering0.4%
  • Other1.3%

Topics

  • Epigenetics and DNA Methylation4.9%
  • CRISPR and Genetic Engineering3.1%
  • Genomics and Chromatin Dynamics3%
  • Pluripotent Stem Cells Research2.6%
  • RNA modifications and cancer2.5%
  • RNA Research and Splicing2%
  • Other81.9%

Coauthors

All papers

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  1. Mapping the Mouse Cell Atlas by Microwell-Seq

    Authors: Xiaoping Han, Renying Wang, Yincong Zhou, Lijiang Fei, Huiyu Sun, Shujing Lai, Assieh Saadatpour, Ziming Zhou, Haide Chen, Fang Ye, Daosheng Huang, Yang Xu, Wentao Huang, Mengmeng Jiang, Xinyi Jiang, Jie Mao, Yao Chen, Chenyu Lu, Jin Xie, Qun Fang, Yibin Wang, Rui Yue, Tiefeng Li, He Huang, Stuart H. Orkin, Guo‐Cheng Yuan, Ming Chen, Guoji Guo - Cell 2018 cited by 1,749

  2. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

    Authors: Stuart H. Orkin, Leonard I. Zon - Cell 2008 cited by 2,552

  3. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

    Authors: Semir Beyaz, Miyeko Mana, Jatin Roper, Dmitriy Kedrin, Assieh Saadatpour, Sue‐Jean Hong, Khristian E. Bauer-Rowe, Michael E. Xifaras, Adam Akkad, Erika Arias, Luca Pinello, Yarden Katz, Shweta Shinagare, Monther Abu-Remaileh, Maria M. Mihaylova, Dudley W. Lamming, Rizkullah Dogum, Guoji Guo, George W. Bell, Martin K. Selig, G. Petur Nielsen, Nitin Gupta, Cristina R. Ferrone, Vikram Deshpande, Guo‐Cheng Yuan, Stuart H. Orkin, David M. Sabatini, Ömer Yılmaz - Nature 2016 cited by 864

  4. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

    Authors: Matthew C. Canver, Elenoe C. Smith, Falak Sher, Luca Pinello, Neville E. Sanjana, Ophir Shalem, Diane D. Chen, Patrick G. Schupp, Divya S. Vinjamur, Sara P. Garcia, Sidinh Luc, Ryo Kurita, Yukio Nakamura, Yuko Fujiwara, Takahiro Maeda, Guo‐Cheng Yuan, Feng Zhang, Stuart H. Orkin, Daniel E. Bauer - Nature 2015 cited by 922

  5. An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

    Authors: Sarah Bowling, Duluxan Sritharan, Fernando G. Osorio, Maximilian Nguyen, Priscilla Cheung, Alejo Rodriguez-Fraticelli, Sachin Patel, Wei-Chien Yuan, Yuko Fujiwara, Bin E. Li, Stuart H. Orkin, Sahand Hormoz, Fernando D. Camargo - Cell 2020 cited by 349

  6. An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

    Authors: Daniel E. Bauer, Sophia C. Kamran, Samuel Lessard, Jian Xu, Yuko Fujiwara, Carrie Lin, Zhen Shao, Matthew C. Canver, Elenoe C. Smith, Luca Pinello, Peter J. Sabo, Jeff Vierstra, Richard A. Voit, Guo‐Cheng Yuan, Matthew H. Porteus, J Stamatoyannopoulos, Guillaume Lettre, Stuart H. Orkin - Science 2013 cited by 673

  7. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

    Authors: Nan Liu, Victoria V. Hargreaves, Qian Zhu, Jesse V. Kurland, Jiyoung A. Hong, Woojin Kim, Falak Sher, Claudio Macias-Treviño, Julia M. Rogers, Ryo Kurita, Yukio Nakamura, Guo‐Cheng Yuan, Daniel E. Bauer, Jian Xu, Martha L. Bulyk, Stuart H. Orkin - Cell 2018 cited by 503

  8. Epigenetic memory in induced pluripotent stem cells

    Authors: K. Kim, Akiko Doi, Bo Wen, Kelvin S. Ng, Robert Chunhua Zhao, Patrick Cahan, Jonghwan Kim, Martin J. Aryee, Hong Ji, Lauren I. R. Ehrlich, Akiko Yabuuchi, Ayumu Takeuchi, K. C. Cunniff, H. Hongguang, Shannon McKinney‐Freeman, Olaia Naveiras, Taeyeong Yoon, Rafael A. Irizarry, Namyoung Jung, Jun Seita, Jacob H. Hanna, Peter Murakami, Rudolf Jaenisch, Ralph Weissleder, Stuart H. Orkin, Irving L. Weissman, Andrew P. Feinberg, George Q. Daley - Nature 2010 cited by 2,307

  9. Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A

    Authors: Vijay G. Sankaran, Tobias Menne, Jian Xu, Thomas E. Akie, Guillaume Lettre, Ben Van Handel, Hanna Mikkola, Joel N. Hirschhorn, Alan Cantor, Stuart H. Orkin - Science 2008 cited by 911

  10. EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

    Authors: Xiaohua Shen, Yingchun Liu, Yu-Jung Hsu, Yuko Fujiwara, Jonghwan Kim, Xiaohong Mao, Guo‐Cheng Yuan, Stuart H. Orkin - Molecular Cell 2008 cited by 1,010

  11. Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis

    Authors: Semir Beyaz, Charlie Chung, Haiwei Mou, Khristian E. Bauer-Rowe, Michael E. Xifaras, Ilgin Ergin, Lenka Dohnalová, Moshe Biton, Karthik Shekhar, Onur Eskiocak, Katherine Papciak, Kadir Ozler, Mohammad Almeqdadi, Brian Yueh, Miriam R. Fein, Damodaran Annamalai, Eider Valle-Encinas, Ayşegül Demirhan Erdemir, Karoline Dogum, Vyom Shah, Aybuke Alici-Garipcan, Hannah V. Meyer, Deniz M. Özata, Eran Elinav, Alper Küçükural, Pawan Kumar, Jeremy P. McAleer, James G. Fox, Christoph A. Thaiss, Aviv Regev, Jatin Roper, Stuart H. Orkin, Ömer Yılmaz - Cell stem cell 2021 cited by 138

  12. Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation

    Authors: Boris G. Wilson, Xi Wang, Xiaohua Shen, Elizabeth S. McKenna, Madeleine E. Lemieux, Yoon-Jae Cho, Edward C. Koellhoffer, Scott L. Pomeroy, Stuart H. Orkin, Charles W.M. Roberts - Cancer Cell 2010 cited by 641

  13. Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

    Authors: Manuela Uda, Renzo Galanello, Serena Sanna, Guillaume Lettre, Vijay G. Sankaran, Wei‐Min Chen, Gianluca Usala, Fabio Busonero, Andrea Maschio, Giuseppe Albai, Maria Grazia Piras, Natascia Sestu, Sandra Lai, Mariano Dei, Antonella Mulas, Laura Crisponi, Silvia Naitza, Isadora Asunis, Manila Deiana, Ramaiah Nagaraja, Lucia Perseu, Stefania Satta, Maria Dolores Cipollina, Carla Sollaino, Paolo Moi, Joel N. Hirschhorn, Stuart H. Orkin, Gonçalo R. Abecasis, David Schlessinger, Antonio Cao - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 672

  14. Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

    Authors: Takeshi Masuda, Xin Wang, Manami Maeda, Matthew C. Canver, Falak Sher, Alister P. W. Funnell, Chris Fisher, Maria Suciu, Gabriella E. Martyn, Laura J. Norton, Catherine Zhu, Ryo Kurita, Yukio Nakamura, Jian Xu, Douglas R. Higgs, Merlin Crossley, Daniel E. Bauer, Stuart H. Orkin, Peter V. Kharchenko, Takahiro Maeda - Science 2016 cited by 378

  15. ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

    Authors: Jochen C. Hartner, Carl R. Walkley, Jun Lü, Stuart H. Orkin - Nature Immunology 2008 cited by 486

  16. Live-animal imaging of native haematopoietic stem and progenitor cells

    Authors: Constantina Christodoulou, Joel A. Spencer, Shu-Chi Yeh, Raphaël Turcotte, Konstantinos D. Kokkaliaris, Riccardo Panero, Azucena Ramos, Guoji Guo, Negar Seyedhassantehrani, Tatiana V. Esipova, Sergei A. Vinogradov, Sarah Rudzinskas, Yi Zhang, Archibald S. Perkins, Stuart H. Orkin, Raffaele Calogero, Timm Schroeder, Charles P. Lin, Fernando D. Camargo - Nature 2020 cited by 246

  17. MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets

    Authors: Zhen Shao, Yijing Zhang, Guo‐Cheng Yuan, Stuart H. Orkin, David J. Waxman - Genome biology 2012 cited by 459

  18. SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

    Authors: Kimberly H. Kim, Woojin Kim, Thomas P. Howard, Francisca Vázquez, Aviad Tsherniak, Jennifer N. Wu, Weishan Wang, Jeffrey R. Haswell, Loren D. Walensky, William C. Hahn, Stuart H. Orkin, Charles W.M. Roberts - Nature Medicine 2015 cited by 412

  19. Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library

    Authors: Jean‐François Rual, Julián Cerón, John Koreth, Tong Hao, Anne‐Sophie Nicot, Tomoko Hirozane-Kishikawa, Jean Vandenhaute, Stuart H. Orkin, David E. Hill, Sander van den Heuvel, Marc Vidal - Genome Research 2004 cited by 978

  20. MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

    Authors: B. Nelson Chau, Cuiyan Xin, Jochen C. Hartner, Shuyu Ren, Ana P. Castaño, Geoffrey Linn, Jian Li, Phong T. Tran, Vivek Kaimal, Xinqiang Huang, Aaron N. Chang, Shenyang Li, Aarti Kalra, Mónica Grafals, Didier Portilla, Deidre A. MacKenna, Stuart H. Orkin, Jeremy S. Duffield - Science Translational Medicine 2012 cited by 581

  21. Analyzing CRISPR genome-editing experiments with CRISPResso

    Authors: Luca Pinello, Matthew C. Canver, Megan D. Hoban, Stuart H. Orkin, Donald B. Kohn, Daniel E. Bauer, Guo‐Cheng Yuan - Nature Biotechnology 2016 cited by 498

  22. Transcription control by the ENL YEATS domain in acute leukaemia

    Authors: Michael A. Erb, Thomas G. Scott, Bin E. Li, Huafeng Xie, Joshiawa Paulk, Hyuk‐Soo Seo, Amanda Souza, Justin M. Roberts, Shiva Dastjerdi, Dennis L. Buckley, Neville E. Sanjana, Ophir Shalem, Behnam Nabet, Rhamy Zeid, Nana K. Offei-Addo, Sirano Dhe‐Paganon, Feng Zhang, Stuart H. Orkin, Georg E. Winter, James E. Bradner - Nature 2017 cited by 328

  23. Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

    Authors: Jennifer A. Perry, Adam Kieżun, Peter Tonzi, Eliezer M. Van Allen, Scott L. Carter, Sylvan C. Baca, Glenn S. Cowley, Ami S. Bhatt, Esther Rheinbay, Chandra Sekhar Pedamallu, Elena Helman, Amaro Taylor‐Weiner, Aaron McKenna, David S. DeLuca, Michael S. Lawrence, Lauren Ambrogio, Carrie Sougnez, Andrey Sivachenko, Loren D. Walensky, Nikhil Wagle, Jaume Mora, Carmen de Torres, Cinzia Lavarino, Simone dos Santos Aguiar, José Andrés Yunes, Sílvia Regina Brandalise, Gabriela Mercado, Jorge Meléndez-Zajgla, Rocío Cárdenas‐Cardós, Liliana Velasco‐Hidalgo, Charles W.M. Roberts, Levi A. Garraway, Carlos Rodríguez‐Galindo, Stacey Gabriel, Eric S. Lander, Todd R. Golub, Stuart H. Orkin, Gad Getz, Katherine A. Janeway - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 501

  24. Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

    Authors: Jonathan Pollock, David A. Williams, Mary A. Gifford, Ling Lin Li, Xunxiang Du, Jason S. Fisherman, Stuart H. Orkin, Claire M. Doerschuk, Mary C. Dinauer - Nature Genetics 1995 cited by 927