Thomas R. Cech
Active 1977–2025
- 207
- Papers
- 51,927
- Citations
- 125
- h-index
- 202
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology69.2%
- Medicine21.5%
- Agricultural and Biological Sciences2.7%
- Physics and Astronomy2%
- Immunology and Microbiology1.3%
- Environmental Science0.6%
- Other2.7%
Topics
- RNA and protein synthesis mechanisms11.3%
- RNA modifications and cancer8.9%
- RNA Research and Splicing7.8%
- Telomeres, Telomerase, and Senescence6%
- Advanced biosensing and bioanalysis techniques5.2%
- DNA and Nucleic Acid Chemistry4.9%
- Other55.9%
Coauthors
- Arthur J. Zaug32
- Anne R. Gooding17
- Elaine R. Podell15
- Karen J. Goodrich15
- Xueyin Wang9
- Joachim Lingner8
- Daniel Herschlag7
- Chen Davidovich6
- Jens C. Schmidt6
- Ming Lei6
- Peter Baumann6
- Yicheng Long6
- Jennifer A. Doudna5
- Anna Marie Pyle4
- Ci Ji Lim4
- Daniel T. Youmans4
- Felicia L. Murphy4
- Jacob C. Schwartz4
- John L. Rinn4
- Joseph A. Piccirilli4
- Paula J. Grabowski4
- Richard D. Paucek4
- Tracy M. Bryan4
- Barbara L. Golden3
All papers
- The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
Authors: Thomas R. Cech, Joan A. Steitz - Cell 2014 cited by 2,573
- RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
Authors: Zhipeng Lu, Qiangfeng Cliff Zhang, Byron Lee, Ryan A. Flynn, Martin A. Smith, James Robinson, Chen Davidovich, Anne R. Gooding, Karen J. Goodrich, John S. Mattick, Jill P. Mesirov, Thomas R. Cech, Howard Y. Chang - Cell 2016 cited by 713
- Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena
Authors: Kelly Kruger, Paula J. Grabowski, Arthur J. Zaug, Julie Sands, Daniel E. Gottschling, Thomas R. Cech - Cell 1982 cited by 2,332
- How do lncRNAs regulate transcription?
Authors: Yicheng Long, Xueyin Wang, Daniel T. Youmans, Thomas R. Cech - Science Advances 2017 cited by 706
- Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization
Authors: Ci Ji Lim, Thomas R. Cech - Nature Reviews Molecular Cell Biology 2021 cited by 277
- Structural basis for inactivation of PRC2 by G-quadruplex RNA
Authors: Jiarui Song, Anne R. Gooding, Wayne O. Hemphill, Brittney Love, Anne L. Robertson, Liqi Yao, Leonard I. Zon, Trista E. North, Vignesh Kasinath, Thomas R. Cech - Science 2023 cited by 68
- Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation
Authors: Katerina Kraft, Kathryn E. Yost, Sedona E. Murphy, Andreas Magg, Yicheng Long, M. Ryan Corces, Jeffrey M. Granja, Lars Wittler, Stefan Mundlos, Thomas R. Cech, Alistair N. Boettiger, Howard Y. Chang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 109
- RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells
Authors: Yicheng Long, Taeyoung Hwang, Anne R. Gooding, Karen J. Goodrich, John L. Rinn, Thomas R. Cech - Nature Genetics 2020 cited by 154
- Biochemical Properties and Biological Functions of FET Proteins
Authors: Jacob C. Schwartz, Thomas R. Cech, Roy Parker - Annual Review of Biochemistry 2014 cited by 235
- Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines
Authors: Xueyin Wang, Karen J. Goodrich, Anne R. Gooding, Haroon Naeem, Stuart K. Archer, Richard D. Paucek, Daniel T. Youmans, Thomas R. Cech, Chen Davidovich - Molecular Cell 2017 cited by 234
- The chemical repertoire of natural ribozymes
Authors: Jennifer A. Doudna, Thomas R. Cech - Nature 2002 cited by 764
- The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2
Authors: Chen Davidovich, Thomas R. Cech - RNA 2015 cited by 301
- Monovalent cation-induced structure of telomeric DNA: The G-quartet model
Authors: James R. Williamson, M. K. Raghuraman, Thomas R. Cech - Cell 1989 cited by 1,236
- The POT1–TPP1 telomere complex is a telomerase processivity factor
Authors: Feng Wang, Elaine R. Podell, Arthur J. Zaug, Yuting Yang, Paul Baciu, Thomas R. Cech, Ming Lei - Nature 2007 cited by 712
- Promiscuous RNA binding by Polycomb repressive complex 2
Authors: Chen Davidovich, Léon Zheng, Karen J. Goodrich, Thomas R. Cech - Nature Structural & Molecular Biology 2013 cited by 447
- TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer
Authors: Neeraj Agarwal, Sébastien Rinaldetti, Bassem Ben Cheikh, Qiong Zhou, Evan P. Hass, Robert T. Jones, Molishree Joshi, Daniel V. LaBarbera, Simon Knott, Thomas R. Cech, Dan Theodorescu - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 60
- RNA Seeds Higher-Order Assembly of FUS Protein
Authors: Jacob C. Schwartz, Xueyin Wang, Elaine R. Podell, Thomas R. Cech - Cell Reports 2013 cited by 338
- Inhibition of telomerase by G-quartet DMA structures
Authors: Alan M. Zahler, James R. Williamson, Thomas R. Cech, David M. Prescott - Nature 1991 cited by 1,123
- The Ribosome Is a Ribozyme
Authors: Thomas R. Cech - Science 2000 cited by 378
- Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA
Authors: Xueyin Wang, Richard D. Paucek, Anne R. Gooding, Zachary Z. Brown, Eva J. Ge, Tom W. Muir, Thomas R. Cech - Nature Structural & Molecular Biology 2017 cited by 228
- Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
Authors: Toru Nakamura, Gregg B. Morin, Karen Chapman, Scott L. Weinrich, William H. Andrews, Joachim Lingner, Calvin B. Harley, Thomas R. Cech - Science 1997 cited by 2,274
- TERT promoter mutations and telomerase reactivation in urothelial cancer
Authors: Sumit Borah, Linghe Xi, Arthur J. Zaug, Natasha M. Powell, Garrett M. Dancik, Scott B. Cohen, James C. Costello, Dan Theodorescu, Thomas R. Cech - Science 2015 cited by 296
- In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
Authors: Thomas R. Cech, Arthur J. Zaug, Paula J. Grabowski - Cell 1981 cited by 894
- The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity
Authors: Jayakrishnan Nandakumar, Caitlin Bell, Ina Weidenfeld, Arthur J. Zaug, Leslie A. Leinwand, Thomas R. Cech - Nature 2012 cited by 354
