Dan Theodorescu
Active 1990–2025
- 140
- Papers
- 25,605
- Citations
- 86
- h-index
- 137
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology49.3%
- Medicine40.8%
- Immunology and Microbiology3%
- Chemistry1.9%
- Engineering1.5%
- Computer Science1%
- Other2.5%
Topics
- Cancer Genomics and Diagnostics8.7%
- Bladder and Urothelial Cancer Treatments4.1%
- Cancer Cells and Metastasis3.2%
- Epigenetics and DNA Methylation3%
- MicroRNA in disease regulation2.1%
- Extracellular vesicles in disease2%
- Other76.9%
Coauthors
- Henry F. Frierson16
- Michael A. Harding11
- Steven C. Smith11
- David J. McConkey10
- Harald Mischak10
- Mark R. Conaway10
- Charles R. Owens9
- James C. Costello9
- Jae K. Lee8
- Garret M. Hampton7
- Gary Oxford7
- Jason E. Duex7
- M. Scott Lucia7
- Tahlita C.M. Zuiverloon7
- Catherine M. Tangen6
- Charles J. Rosser6
- Hany Abdel-Hafiz6
- John J Gildea6
- Joshua J. Coon6
- Melissa Plets6
- Seth P. Lerner6
- Siamak Daneshmand6
- Thomas W. Flaig6
- Amir Goldkorn5
All papers
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Authors: Chetan Bettegowda, Mark Sausen, Rebecca Leary, Isaac Kinde, Yuxuan Wang, Nishant Agrawal, Bjarne R. Bartlett, Hao Wang, Brandon Luber, Rhoda M. Alani, Emmanuel S. Antonarakis, Nilofer S. Azad, Alberto Bardelli, Henry Brem, John L. Cameron, Clarence Lee, Leslie A. Fecher, Gary L. Gallia, Peter Gibbs, Dung T. Le, Robert Giuntoli, Michael Goggins, Michael D. Hogarty, Matthias Holdhoff, Seung‐Mo Hong, Yuchen Jiao, Hartmut Juhl, Jaeyeon Kim, Giulia Siravegna, Daniel A. Laheru, Calogero Lauricella, Michael Lim, Evan J. Lipson, Suely Kazue Nagahashi Marie, George J. Netto, Kelly S. Oliner, Alessandro Olivi, Louise Olsson, Gregory J. Riggins, Andrea Sartore‐Bianchi, Kerstin Schmidt, le-Ming Shih, Sueli Mieko Oba‐Shinjo, Salvatore Siena, Dan Theodorescu, Jeanne Tie, Timothy T. Harkins, Silvio Veronese, Tian‐Li Wang, Jon Weingart, Christopher L. Wolfgang, Laura D. Wood, Dongmei Xing, Ralph H. Hruban, Jian Wu, Peter J. Allen, C. Max Schmidt, Michael A. Choti, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos, Luis A. Díaz - Science Translational Medicine 2014 cited by 5,110
- Advances in bladder cancer biology and therapy
Authors: Linda L. Tran, Jin-Fen Xiao, Neeraj Agarwal, Jason E. Duex, Dan Theodorescu - Nature reviews. Cancer 2020 cited by 794
- Bladder cancer
Authors: Lars Dyrskjøt, Donna E. Hansel, Jason A. Efstathiou, Margaret A. Knowles, Matthew D. Galsky, Jeremy Yuen‐Chun Teoh, Dan Theodorescu - Nature Reviews Disease Primers 2023 cited by 480
- The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations
Authors: Yuanbin Ru, Katerina Kechris, Boris Tabakoff, Paula Hoffman, Richard A. Radcliffe, Russell P. Bowler, Spencer Mahaffey, Simona Rossi, George A. Călin, Lynne Bemis, Dan Theodorescu - Nucleic Acids Research 2014 cited by 774
- Y chromosome loss in cancer drives growth by evasion of adaptive immunity
Authors: Hany Abdel-Hafiz, Johanna M. Schafer, Xingyu Chen, Tong Xiao, Timothy D. Gauntner, Zihai Li, Dan Theodorescu - Nature 2023 cited by 178
- TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Authors: Patrick Killela, Zachary J. Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A. Díaz, Allan H. Friedman, Henry S. Friedman, Gary L. Gallia, Beppino C. Giovanella, Arthur P. Grollman, Tong‐Chuan He, Yiping He, Ralph H. Hruban, George I. Jallo, Nils Mandahl, Alan K. Meeker, Fredrik Mertens, George J. Netto, B. Ahmed Rasheed, Gregory J. Riggins, Thomas A. Rosenquist, Mark Schiffman, Ie‐Ming Shih, Dan Theodorescu, Michael Torbenson, Victor E. Velculescu, Tian‐Li Wang, Nicolas Wentzensen, Laura D. Wood, Ming Zhang, Roger E. McLendon, Darell D. Bigner, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos, Hai Yan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 1,375
- An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer
Authors: Kenneth Gouin, Nathan Ing, Jasmine Plummer, Charles J. Rosser, Bassem Ben Cheikh, Catherine Oh, Stephanie S. Chen, Keith Syson Chan, Hideki Furuya, Warren G. Tourtellotte, Simon Knott, Dan Theodorescu - Nature Communications 2021 cited by 177
- Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy
Authors: Megan M. Tu, Hany Abdel-Hafiz, Robert T. Jones, Annie Jean, Katelyn J. Hoff, Jason E. Duex, Ana Chauca-Diaz, James C. Costello, Garrett M. Dancik, Beth A. Jirón Tamburini, Bogdan Czerniak, Jonathan Kaye, Dan Theodorescu - Communications Biology 2020 cited by 172
- The Molecular Twin artificial-intelligence platform integrates multi-omic data to predict outcomes for pancreatic adenocarcinoma patients
Authors: Arsen Osipov, Ognjen Nikolic, Arkadiusz Gertych, Sarah J. Parker, Andrew Hendifar, Pranav Singh, Darya Filippova, Grant Dagliyan, Cristina R. Ferrone, Lei Zheng, Jason H. Moore, Warren G. Tourtellotte, Jennifer E. Van Eyk, Dan Theodorescu - Nature Cancer 2024 cited by 83
- The dynamic roles of the bladder tumour microenvironment
Authors: Yu‐Cheng Lee, Hung‐Ming Lam, Charles J. Rosser, Dan Theodorescu, William C. Parks, Keith Syson Chan - Nature Reviews Urology 2022 cited by 110
- Non–muscle-invasive bladder cancer molecular subtypes predict differential response to intravesical Bacillus Calmette-Guérin
Authors: Florus C. de Jong, Teemu D. Laajala, Robert F. Hoedemaeker, Kimberley R. Jordan, Angelique C. J. van der Made, Egbert R. Boevé, Deric K. E. van der Schoot, Bart Nieuwkamer, Emiel A. M. Janssen, Tokameh Mahmoudi, Joost L. Boormans, Dan Theodorescu, James C. Costello, Tahlita C.M. Zuiverloon - Science Translational Medicine 2023 cited by 85
- Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease
Authors: David M. Good, Petra Zürbig, Àngel Argilés, H Bauer, Georg Behrens, Joshua J. Coon, Mohammed Dakna, Stéphane Decramer, Christian Delles, Anna F. Dominiczak, J. H. H. Ehrich, Frank Eitner, Danilo Fliser, Moritz Frommberger, Arnold Ganser, Mark Girolami, Igor Golovko, Wilfried Gwinner, Marion Haubitz, Stefan Herget‐Rosenthal, Joachim Jankowski, Holger Jahn, George Jerums, Bruce A. Julian, Markus Kellmann, Volker Kliem, Walter Kölch, Andrzej S. Królewski, Mario Luppi, Ziad A. Massy, Michael Melter, Christian Neusüß, Jan Novák, Karlheinz Peter, Kasper Rossing, Harald Rupprecht, Joost P. Schanstra, Eric Schiffer, Jens‐Uwe Stolzenburg, Lise Tarnow, Dan Theodorescu, Visith Thongboonkerd, Raymond Vanholder, Eva M. Weissinger, Harald Mischak, Philippe Schmitt‐Kopplin - Molecular & Cellular Proteomics 2010 cited by 538
- Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
Authors: Marie S. Ostenfeld, Dennis K. Jeppesen, Jens R. Laurberg, Anders T. Boysen, Jesper B. Bramsen, Bjarke Primdal-Bengtson, An Hendrix, Philippe Lamy, Frederik Dagnæs‐Hansen, Mads H. Rasmussen, Khan H. Bui, Niels Fristrup, Erik Christensen, Iver Nordentoft, Jens Preben Morth, Jørgen Bjerggaard Jensen, Jakob Skou Pedersen, Martin Beck, Dan Theodorescu, Michael Borre, Kenneth A. Howard, Lars Dyrskjøt, Torben F. Ørntoft - Cancer Research 2014 cited by 297
- Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
Authors: Yaoting Gui, Guangwu Guo, Yi Huang, Xueda Hu, Aifa Tang, Shengjie Gao, Renhua Wu, Chao Chen, Xianxin Li, Liang Zhou, Minghui He, Zesong Li, Xiaojuan Sun, Wenlong Jia, Jinnong Chen, Shangming Yang, Fangjian Zhou, Xiaokun Zhao, Shengqing Wan, Rui Ye, Chang Yin Liang, Zhisheng Liu, Peide Huang, Chunxiao Liu, Hui Jiang, Yong Wang, Hancheng Zheng, Liang Sun, Xingwang Liu, Zhimao Jiang, Dafei Feng, Jing Chen, Song Wu, Jing Zou, Zhang Zhong-fu, Ruilin Yang, Jun Zhao, Congjie Xu, Weihua Yin, Zhichen Guan, Jiongxian Ye, Hong Zhang, Jingxiang Li, Karsten Kristiansen, Michael L. Nickerson, Dan Theodorescu, Yingrui Li, Xiuqing Zhang, Songgang Li, Jian Wang, Huanming Yang, Jun Wang, Zhiming Cai, Jun Wang, Zhiming Cai - Nature Genetics 2011 cited by 764
- A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer
Authors: Damiano Fantini, Alexander P. Glaser, Kalen Rimar, Yiduo Wang, Matthew J. Schipma, Nobish Varghese, Alfred Rademaker, Amir Behdad, Aparna Yellapa, Yanni Yu, Christie C. Sze, Lu Wang, Zibo Zhao, Susan E. Crawford, Deqing Hu, Jonathan D. Licht, Clayton K. Collings, Elizabeth T. Bartom, Dan Theodorescu, Ali Shilatifard, Joshua J. Meeks - Oncogene 2018 cited by 197
- TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer
Authors: Neeraj Agarwal, Sébastien Rinaldetti, Bassem Ben Cheikh, Qiong Zhou, Evan P. Hass, Robert T. Jones, Molishree Joshi, Daniel V. LaBarbera, Simon Knott, Thomas R. Cech, Dan Theodorescu - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 60
- Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
Authors: Guangwu Guo, Xiaojuan Sun, Chao Chen, Song Wu, Peide Huang, Zesong Li, Michael Dean, Yi Huang, Wenlong Jia, Quan Zhou, Aifa Tang, Zuoquan Yang, Xianxin Li, Pengfei Song, Xiaokun Zhao, Rui Ye, Shiqiang Zhang, Zhao Lin, Mingfu Qi, Shengqing Wan, Liangfu Xie, Fan Fan, Michael L. Nickerson, Xiangjun Zou, Xueda Hu, Xing Li, Zhaojie Lv, Hongbin Mei, Shengjie Gao, Chang Yin Liang, Zhibo Gao, Jingxiao Lu, Yuan Yu, Chunxiao Liu, Lin Li, Xiaodong Fang, Zhimao Jiang, Jie Yang, Cailing Li, Xin Zhao, Jing Chen, Fang Zhang, Yongqi Lai, Zheguang Lin, Fangjian Zhou, Hao Chen, Hsiao Chang Chan, Shirley Tsang, Dan Theodorescu, Yingrui Li, Xiuqing Zhang, Jian Wang, Huanming Yang, Yaoting Gui, Jun Wang, Zhiming Cai, Jun Wang, Zhiming Cai - Nature Genetics 2013 cited by 512
- TERT promoter mutations and telomerase reactivation in urothelial cancer
Authors: Sumit Borah, Linghe Xi, Arthur J. Zaug, Natasha M. Powell, Garrett M. Dancik, Scott B. Cohen, James C. Costello, Dan Theodorescu, Thomas R. Cech - Science 2015 cited by 296
- Targeting DDR2 enhances tumor response to anti–PD-1 immunotherapy
Authors: Megan M. Tu, Francis Y. F. Lee, Robert T. Jones, Abigail K. Kimball, Elizabeth Saravia, Robert F. Graziano, Brianne M. Coleman, Krista Menard, Jun Yan, Erin Michaud, Han Chang, Hany Abdel-Hafiz, Andrii I. Rozhok, Jason E. Duex, Neeraj Agarwal, Ana Chauca-Diaz, Linda K. Johnson, Terry L. Ng, John C. Cambier, Eric T. Clambey, James C. Costello, Alan J. Korman, Dan Theodorescu - Science Advances 2019 cited by 127
- A Randomized Phase II Study of Coexpression Extrapolation (COXEN) with Neoadjuvant Chemotherapy for Bladder Cancer (SWOG S1314; NCT02177695)
Authors: Thomas W. Flaig, Catherine M. Tangen, Siamak Daneshmand, Ajjai Alva, Seth P. Lerner, M. Scott Lucia, David J. McConkey, Dan Theodorescu, Amir Goldkorn, Matthew I. Milowsky, Rick Bangs, Gary R. MacVicar, Bruno R. Bastos, Jared S. Fowles, Daniel L. Gustafson, Melissa Plets, Ian M. Thompson - Clinical Cancer Research 2021 cited by 91
- Assessment of Luminal and Basal Phenotypes in Bladder Cancer
Authors: Charles C. Guo, Jolanta Bondaruk, Hui Yao, Ziqiao Wang, Li Zhang, Sangkyou Lee, June-Goo Lee, David Cogdell, Miao Zhang, Guoliang Yang, Vipulkumar Dadhania, Woonyoung Choi, Peng Wei, Jianjun Gao, Dan Theodorescu, Christopher J. Logothetis, Colin P. Dinney, Marek Kimmel, John N. Weinstein, David J. McConkey, Bogdan Czerniak - Scientific Reports 2020 cited by 171
- Recommendations for Biomarker Identification and Qualification in Clinical Proteomics
Authors: Harald Mischak, Günter Allmaier, Rolf Apweiler, Teresa K. Attwood, Marc Baumann, Ariela Benigni, Samuel Bennett, Rainer Bischoff, Erik Bongcam‐Rudloff, Giovambattista Capasso, Joshua J. Coon, Patrick C. D’Haese, Anna F. Dominiczak, Mohammed Dakna, Hassan Dihazi, J. H. H. Ehrich, Patricia Fernández‐Llama, Danilo Fliser, Jørgen Frøkiær, Jérôme Garin, Mark Girolami, William S. Hancock, Marion Haubitz, Denis F. Hochstrasser, Rury R. Holman, John P. A. Ioannidis, Joachim Jankowski, Bruce A. Julian, Jon B. Klein, Walter Kölch, Theo M. Luider, Ziad A. Massy, William B. Mattes, Franck Molina, Bernard Monsarrat, Jan Novák, Karlheinz Peter, Peter Rossing, Marta Sänchez‐Carbayo, Joost P. Schanstra, O. John Semmes, Goce Spasovski, Dan Theodorescu, Visith Thongboonkerd, Raymond Vanholder, Timothy D. Veenstra, Eva M. Weissinger, Tadashi Yamamoto, Antonia Vlahou - Science Translational Medicine 2010 cited by 335
- Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors
Authors: Caglar Cekic, Duygu Sağ, Yuesheng Li, Dan Theodorescu, Robert M. Strieter, Joel Linden - The Journal of Immunology 2011 cited by 202
- Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers
Authors: Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R. Cech - Genes & Development 2015 cited by 195
