Henry Brem
Active 1974–2025
- 167
- Papers
- 32,118
- Citations
- 92
- h-index
- 162
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine46.7%
- Biochemistry, Genetics and Molecular Biology31%
- Materials Science6.2%
- Engineering4.5%
- Immunology and Microbiology4.4%
- Neuroscience3%
- Other4.2%
Topics
- Glioma Diagnosis and Treatment8.9%
- Cancer Genomics and Diagnostics7.1%
- Cancer Immunotherapy and Biomarkers3%
- Cancer Cells and Metastasis2.8%
- Brain Metastases and Treatment2.8%
- Nanoparticle-Based Drug Delivery2.7%
- Other72.7%
Coauthors
- Betty Tyler53
- Alessandro Olivi34
- Jon Weingart33
- Michael Lim27
- Christopher M. Jackson22
- Judy Huang22
- Gary L. Gallia19
- Debraj Mukherjee16
- Drew M. Pardoll15
- Alfredo Quiñones‐Hinojosa14
- Kaisorn L. Chaichana13
- Rafael J. Tamargo13
- Noah Gorelick12
- Peter C. Burger12
- Chad R. Gordon11
- Chetan Bettegowda11
- Antonella Mangraviti10
- Dimitrios Mathios10
- John Choi10
- Riccardo Serra10
- Allen K. Sills9
- Micah Belzberg9
- Róbert Langer9
- Sakibul Huq9
All papers
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Authors: Chetan Bettegowda, Mark Sausen, Rebecca Leary, Isaac Kinde, Yuxuan Wang, Nishant Agrawal, Bjarne R. Bartlett, Hao Wang, Brandon Luber, Rhoda M. Alani, Emmanuel S. Antonarakis, Nilofer S. Azad, Alberto Bardelli, Henry Brem, John L. Cameron, Clarence Lee, Leslie A. Fecher, Gary L. Gallia, Peter Gibbs, Dung T. Le, Robert Giuntoli, Michael Goggins, Michael D. Hogarty, Matthias Holdhoff, Seung‐Mo Hong, Yuchen Jiao, Hartmut Juhl, Jaeyeon Kim, Giulia Siravegna, Daniel A. Laheru, Calogero Lauricella, Michael Lim, Evan J. Lipson, Suely Kazue Nagahashi Marie, George J. Netto, Kelly S. Oliner, Alessandro Olivi, Louise Olsson, Gregory J. Riggins, Andrea Sartore‐Bianchi, Kerstin Schmidt, le-Ming Shih, Sueli Mieko Oba‐Shinjo, Salvatore Siena, Dan Theodorescu, Jeanne Tie, Timothy T. Harkins, Silvio Veronese, Tian‐Li Wang, Jon Weingart, Christopher L. Wolfgang, Laura D. Wood, Dongmei Xing, Ralph H. Hruban, Jian Wu, Peter J. Allen, C. Max Schmidt, Michael A. Choti, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos, Luis A. Díaz - Science Translational Medicine 2014 cited by 5,110
- Polylactic acid (PLA) controlled delivery carriers for biomedical applications
Authors: Betty Tyler, David Gullotti, Antonella Mangraviti, Tadanobu Utsuki, Henry Brem - Advanced Drug Delivery Reviews 2016 cited by 1,028
- Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology
Authors: Burt Nabors, Jana Portnow, Manmeet S. Ahluwalia, Joachim M. Baehring, Henry Brem, Steven Brem, Nicholas Butowski, Jian Campian, Stephen W. Clark, Andrew J. Fabiano, Peter Forsyth, Jona A. Hattangadi‐Gluth, Matthias Holdhoff, Craig Horbinski, Larry Junck, Thomas Kaley, Priya Kumthekar, Jay S. Loeffler, Maciej M. Mrugała, Seema Nagpal, Manjari Pandey, Ian F. Parney, Katherine B. Peters, Vinay K. Puduvalli, Ian Robins, Jason K. Rockhill, Chad G. Rusthoven, Nicole Shonka, Dennis C. Shrieve, Lode J. Swinnen, Stephanie E. Weiss, Patrick Y. Wen, Nicole E. Willmarth, Mary Anne Bergman, Susan Darlow - Journal of the National Comprehensive Cancer Network 2020 cited by 564
- Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas
Authors: Jing Zeng, Alfred P. See, Jillian Phallen, Christopher M. Jackson, Zineb Belcaid, Jacob Ruzevick, Nicholas M. Durham, Christian F. Meyer, Timothy Harris, Emilia Albesiano, Gustavo Pradilla, Eric Ford, John W. Wong, Hans-Joerg Hammers, Dimitris Mathios, Betty Tyler, Henry Brem, Phuoc T. Tran, Drew M. Pardoll, Charles G. Drake, Michael Lim - International Journal of Radiation Oncology*Biology*Physics 2013 cited by 898
- Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas
Authors: Jennifer E. Kim, Mira Patel, Antonella Mangraviti, Eileen Kim, Debebe Theodros, Esteban Velarde, Ann Liu, Eric W. Sankey, Ada Tam, Haiying Xu, Dimitrios Mathios, Christopher M. Jackson, Sarah Harris‐Bookman, Tomás Garzón-Muvdi, Mary Sheu, Allison Martin, Betty Tyler, Phuoc T. Tran, Xiaobu Ye, Alessandro Olivi, Janis M. Taube, Peter C. Burger, Charles G. Drake, Henry Brem, Drew M. Pardoll, Michael Lim - Clinical Cancer Research 2016 cited by 463
- TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM
Authors: Alice Hung, Russell Maxwell, Debebe Theodros, Zineb Belcaid, Dimitrios Mathios, Andrew S. Luksik, Eileen Kim, Adela Wu, Yuanxuan Xia, Tomás Garzón-Muvdi, Christopher M. Jackson, Xiaobu Ye, Betty Tyler, M. J. Selby, Alan J. Korman, Bryan C. Barnhart, Su-Myeong Park, Je-In Youn, Tamrin Chowdhury, Chul‐Kee Park, Henry Brem, Drew M. Pardoll, Michael Lim - OncoImmunology 2018 cited by 333
- Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord
Authors: Yuxuan Wang, Simeon Springer, Ming Zhang, K. Wyatt McMahon, Isaac Kinde, Lisa Dobbyn, Janine Ptak, Henry Brem, Kaisorn L. Chaichana, Gary L. Gallia, Ziya L. Gokaslan, Mari L. Groves, George I. Jallo, Michael Lim, Alessandro Olivi, Alfredo Quiñones‐Hinojosa, Daniele Rigamonti, Greg Riggins, Daniel M. Sciubba, Jon Weingart, Jean‐Paul Wolinsky, Xiaobu Ye, Sueli Mieko Oba‐Shinjo, Suely Kazue Nagahashi Marie, Matthias Holdhoff, Nishant Agrawal, Luis A. Díaz, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Chetan Bettegowda - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 474
- Paclitaxel: a review of adverse toxicities and novel delivery strategies
Authors: Neena I. Marupudi, James E. Han, Khan W. Li, Violette M. Renard, Betty Tyler, Henry Brem - Expert Opinion on Drug Safety 2007 cited by 510
- Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma
Authors: Feihu Wang, Qian Huang, Hao Su, Mingjiao Sun, Zeyu Wang, Ziqi Chen, Mengzhen Zheng, Rami W. Chakroun, Maya K. Monroe, Daiqing Chen, Zongyuan Wang, Noah Gorelick, Riccardo Serra, Han Wang, Yun Guan, Jung Soo Suk, Betty Tyler, Henry Brem, Justin Hanes, Honggang Cui - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 68
- Expression of LAG‐3 and efficacy of combination treatment with anti‐LAG‐3 and anti‐PD‐1 monoclonal antibodies in glioblastoma
Authors: Sarah Harris‐Bookman, Dimitrios Mathios, Allison Martin, Yuanxuan Xia, Eileen Kim, Haiying Xu, Zineb Belcaid, Magdalena Polanczyk, Theresa J. Barberi, Debebe Theodros, Jennifer Kim, Janis M. Taube, Peter C. Burger, M. J. Selby, Corina Taitt, Alan J. Korman, Xiaobu Ye, Charles G. Drake, Henry Brem, Drew M. Pardoll, Michael Lim - International Journal of Cancer 2018 cited by 159
- Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
Authors: Henry Brem, Steven Piantadosi, P. C. Burger, Melissa Walker, Robert G. Selker, Nicholas A. Vick, Keith L. Black, Michael B. Sisti, Steven Brem, Gérard Mohr, P Muller, Richard B. Morawetz, S. Clifford Schold - The Lancet 1995 cited by 1,382
- Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma
Authors: Kaisorn L. Chaichana, Ignacio Jusué-Torres, Rodrigo Navarro-Ramírez, Shaan M. Raza, María Pascual-Gallego, Aly Ibrahim, Marta Hernandez-Hermann, Luis Miguel Marín Gómez, Xiaobu Ye, Jon Weingart, Alessandro Olivi, Jaishri O. Blakeley, Gary L. Gallia, Michael Lim, Henry Brem, Alfredo Quiñones‐Hinojosa - Neuro-Oncology 2013 cited by 494
- Anti–PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM
Authors: Dimitrios Mathios, Jennifer E. Kim, Antonella Mangraviti, Jillian Phallen, Chul‐Kee Park, Christopher M. Jackson, Tomás Garzón-Muvdi, Eileen Kim, Debebe Theodros, Magdalena Polanczyk, Allison Martin, Ian Suk, Xiaobu Ye, Betty Tyler, Chetan Bettegowda, Henry Brem, Drew M. Pardoll, Michael Lim - Science Translational Medicine 2016 cited by 300
- Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment
Authors: Adela Wu, Russell Maxwell, Yuanxuan Xia, Pina M. Cardarelli, Miho Oyasu, Zineb Belcaid, Eileen Kim, Alice Hung, Andrew S. Luksik, Tomás Garzón-Muvdi, Christopher M. Jackson, Dimitrios Mathios, Debebe Theodros, John Cogswell, Henry Brem, Drew M. Pardoll, Michael Lim - Journal of Neuro-Oncology 2019 cited by 147
- Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
Authors: Julie Sesen, Perrine Dahan, Sarah Scotland, Estelle Saland, V. Dang, Anthony Lemarié, Betty Tyler, Henry Brem, Christine Toulas, Elizabeth Cohen‐Jonathan Moyal, Jean-Emmanuel Sarry, Nicolas Skuli - PLoS ONE 2015 cited by 205
- P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
Authors: Eilam Yeini, Paula Ofek, Sabina Pozzi, Nitzan Albeck, Dikla Ben‐Shushan, Galia Tiram, Sapir Golan, Ron Kleiner, Ron Sheinin, Sahar Israeli Dangoor, Shlomit Reich-Zeliger, Rachel Grossman, Zvi Ram, Henry Brem, Thomas M. Hyde, Prerna Magod, Dinorah Friedmann‐Morvinski, Asaf Madi, Ronit Satchi‐Fainaro - Nature Communications 2021 cited by 78
- Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
Authors: Sara Piccirillo, Brent A. Reynolds, Nadia Zanetti, Giuseppe Lamorte, Elena Binda, Giovanni Broggi, Henry Brem, Alessandro Olivi, Francesco DiMeco, Angelo L. Vescovi - Nature 2006 cited by 1,174
- Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo
Authors: Antonella Mangraviti, Stephany Y. Tzeng, Kristen Kozielski, Yuan Wang, Yike Jin, David Gullotti, Mariangela Pedone, Nitsa Buaron, Ann Liu, David R. Wilson, Sarah K. Hansen, Fausto J. Rodríguez, Guo-Dong Gao, Francesco DiMeco, Henry Brem, Alessandro Olivi, Betty Tyler, Jordan J. Green - ACS Nano 2015 cited by 252
- NCCN Guidelines Insights: Central Nervous System Cancers, Version 1.2017
Authors: Burt Nabors, Jana Portnow, Mario Ammirati, Joachim M. Baehring, Henry Brem, Nicholas Butowski, Robert A. Fenstermaker, Peter Forsyth, Jona A. Hattangadi‐Gluth, Matthias Holdhoff, Steven Howard, Larry Junck, Thomas Kaley, Priya Kumthekar, Jay S. Loeffler, Paul L. Moots, Maciej M. Mrugała, Seema Nagpal, Manjari Pandey, Ian F. Parney, Katherine B. Peters, Vinay K. Puduvalli, John W. Ragsdale, Jason K. Rockhill, Lisa R. Rogers, Chad G. Rusthoven, Nicole Shonka, Dennis C. Shrieve, Allen K. Sills, Lode J. Swinnen, Christina Tsien, Stephanie E. Weiss, Patrick Y. Wen, Nicole E. Willmarth, Mary Anne Bergman, Anita M. Engh - Journal of the National Comprehensive Cancer Network 2017 cited by 231
- Combination checkpoint therapy with anti-PD-1 and anti-BTLA results in a synergistic therapeutic effect against murine glioblastoma
Authors: John Choi, Ravi Medikonda, Laura Saleh, Timothy Kim, Ayush Pant, Siddhartha Srivastava, Young‐Hoon Kim, Christina Jackson, Luqing Tong, Denis Routkevitch, Christopher M. Jackson, Dimitrios Mathios, Tianna Zhao, Hyerim Cho, Henry Brem, Michael Lim - OncoImmunology 2021 cited by 48
- The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function
Authors: Christopher M. Jackson, Ayush Pant, Wikum Dinalankara, John Choi, Aanchal Jain, Ryan T. Nitta, Eli Yazigi, Laura Saleh, Liang Zhao, Thomas R. Nirschl, Christina M. Kochel, Brandon Hwa-Lin Bergsneider, Denis Routkevitch, Kisha Patel, Kwang Bog Cho, Stephany Y. Tzeng, Sarah Y. Neshat, Young‐Hoon Kim, Barbara J. Smith, María C. Ramello, Elena Sotillo, Xinnan Wang, Jordan J. Green, Chetan Bettegowda, Gordon Li, Henry Brem, Crystal L. Mackall, Drew M. Pardoll, Charles G. Drake, Luigi Marchionni, Michael Lim - Immunity 2024 cited by 43
- MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression
Authors: Sabina Pozzi, Anna Scomparin, Dikla Ben‐Shushan, Eilam Yeini, Paula Ofek, Alessio D. Nahmad, Shelly Soffer, Ariel Ionescu, Antonella Ruggiero, Adi Barzel, Henry Brem, Thomas M. Hyde, Iris Barshack, Sanju Sinha, Eytan Ruppin, Tomer Weiss, Asaf Madi, Eran Perlson, Inna Slutsky, Helena F. Florindo, Ronit Satchi‐Fainaro - JCI Insight 2022 cited by 29
- Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats
Authors: Clark Zhang, Elizabeth Nance, Panagiotis Mastorakos, Jane Chisholm, Sneha Berry, Charles G. Eberhart, Betty Tyler, Henry Brem, Jung Soo Suk, Justin Hanes - Journal of Controlled Release 2017 cited by 129
- Independent association of extent of resection with survival in patients with malignant brain astrocytoma
Authors: Matthew J. McGirt, Kaisorn L. Chaichana, Muraya Gathinji, Frank J. Attenello, Khoi D. Than, Alessandro Olivi, Jon Weingart, Henry Brem, Alf redo Quiñones-Hinojosa - Journal of neurosurgery 2008 cited by 814
