Daniel A. Laheru
Active 2001–2025
- 105
- Papers
- 33,957
- Citations
- 78
- h-index
- 101
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine59.2%
- Biochemistry, Genetics and Molecular Biology29.9%
- Immunology and Microbiology6.9%
- Engineering1.1%
- Materials Science1.1%
- Neuroscience0.4%
- Other1.4%
Topics
- Pancreatic and Hepatic Oncology Research12%
- Cancer Genomics and Diagnostics8.8%
- Cancer Immunotherapy and Biomarkers6.4%
- Cancer Cells and Metastasis3.9%
- Immunotherapy and Immune Responses3.6%
- Cholangiocarcinoma and Gallbladder Cancer Studies2.1%
- Other63.2%
Coauthors
- Christopher L. Wolfgang37
- Elizabeth M. Jaffee37
- Lei Zheng35
- Joseph M. Herman32
- Ralph H. Hruban30
- Dung T. Le25
- Ana De Jesus‐Acosta21
- John L. Cameron21
- Jin He18
- Robert A. Anders16
- Amol Narang15
- Matthew J. Weiss15
- Ross C. Donehower15
- Hao Wang14
- Jennifer N. Durham14
- Manuel Hidalgo14
- Timothy M. Pawlik14
- Nilofer S. Azad12
- Anirban Maitra11
- Christine A. Iacobuzio–Donahue11
- Mark Yarchoan11
- Michael Goggins11
- Qingfeng Zhu11
- Alison P. Klein10
All papers
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Authors: Chetan Bettegowda, Mark Sausen, Rebecca Leary, Isaac Kinde, Yuxuan Wang, Nishant Agrawal, Bjarne R. Bartlett, Hao Wang, Brandon Luber, Rhoda M. Alani, Emmanuel S. Antonarakis, Nilofer S. Azad, Alberto Bardelli, Henry Brem, John L. Cameron, Clarence Lee, Leslie A. Fecher, Gary L. Gallia, Peter Gibbs, Dung T. Le, Robert Giuntoli, Michael Goggins, Michael D. Hogarty, Matthias Holdhoff, Seung‐Mo Hong, Yuchen Jiao, Hartmut Juhl, Jaeyeon Kim, Giulia Siravegna, Daniel A. Laheru, Calogero Lauricella, Michael Lim, Evan J. Lipson, Suely Kazue Nagahashi Marie, George J. Netto, Kelly S. Oliner, Alessandro Olivi, Louise Olsson, Gregory J. Riggins, Andrea Sartore‐Bianchi, Kerstin Schmidt, le-Ming Shih, Sueli Mieko Oba‐Shinjo, Salvatore Siena, Dan Theodorescu, Jeanne Tie, Timothy T. Harkins, Silvio Veronese, Tian‐Li Wang, Jon Weingart, Christopher L. Wolfgang, Laura D. Wood, Dongmei Xing, Ralph H. Hruban, Jian Wu, Peter J. Allen, C. Max Schmidt, Michael A. Choti, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos, Luis A. Díaz - Science Translational Medicine 2014 cited by 5,110
- Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
Authors: Daniel D. Von Hoff, Thomas J. Ervin, Francis P. Arena, E. Gabriela Chiorean, Jeffrey R. Infante, Malcolm J. Moore, Thomas E. Seay, Sergei Tjulandin, Wen Wee, Mansoor N. Saleh, Marion Harris, Michele Reni, Scot Dowden, Daniel A. Laheru, Nathan Bahary, Ramesh K. Ramanathan, Josep Tabernero, Manuel Hidalgo, David Goldstein, Eric Van Cutsem, Xinyu Wei, José Iglesias, Markus F. Renschler - New England Journal of Medicine 2013 cited by 6,661
- Targeting neoantigens to augment antitumour immunity
Authors: Mark Yarchoan, Burles A. Johnson, Eric R. Lutz, Daniel A. Laheru, Elizabeth M. Jaffee - Nature reviews. Cancer 2017 cited by 1,032
- Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity
Authors: Won Jin Ho, Qingfeng Zhu, Jennifer N. Durham, Aleksandra Popović, Stephanie Xavier, James M. Leatherman, Aditya Mohan, Guanglan Mo, Shu Zhang, Nicole Groß, Soren Charmsaz, Dongxia Lin, Derek Quong, Brad Wilt, Ihab R. Kamel, Matthew J. Weiss, Benjamin Philosophe, Richard A. Burkhart, William R. Burns, Chris Shubert, Aslam Ejaz, Jin He, Atul Deshpande, Ludmila Danilova, Genevieve Stein-O’Brien, Elizabeth A. Sugar, Daniel A. Laheru, Robert A. Anders, Elana J. Fertig, Elizabeth M. Jaffee, Mark Yarchoan - Nature Cancer 2021 cited by 346
- PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers
Authors: Mark Yarchoan, Lee A. Albacker, Alexander C. Hopkins, Meagan Montesion, Karthikeyan Murugesan, Teena Vithayathil, Neeha Zaidi, Nilofer S. Azad, Daniel A. Laheru, Garrett M. Frampton, Elizabeth M. Jaffee - JCI Insight 2019 cited by 538
- Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer
Authors: Dung T. Le, Andrea Wang‐Gillam, Vincent J. Picozzi, Tim F. Greten, Todd S. Crocenzi, Gregory M. Springett, Michael A. Morse, Herbert J. Zeh, Deirdre Jill Cohen, Robert L. Fine, Beth Onners, Jennifer N. Uram, Daniel A. Laheru, Eric R. Lutz, Sara Solt, Aimee Murphy, Justin Skoble, Ed Lemmens, John Grous, Thomas W. Dubensky, Dirk G. Brockstedt, Elizabeth M. Jaffee - Journal of Clinical Oncology 2015 cited by 600
- Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation
Authors: Eric R. Lutz, Annie A. Wu, Elaine Bigelow, Rajni Sharma, Guanglan Mo, Kevin C. Soares, Sara Solt, Alvin Dorman, Anthony Wamwea, Allison Yager, Daniel A. Laheru, Christopher L. Wolfgang, Jiang Wang, Ralph H. Hruban, Robert A. Anders, Elizabeth M. Jaffee, Lei Zheng - Cancer Immunology Research 2014 cited by 544
- Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy
Authors: Keyu Li, Joseph A. Tandurella, Jessica Gai, Qingfeng Zhu, Su Jin Lim, Dwayne L. Thomas, Tao Xia, Guanglan Mo, Jacob T. Mitchell, Janelle M. Montagne, Melissa R. Lyman, Ludmila Danilova, Jacquelyn W. Zimmerman, Benedict Kinny‐Köster, Tengyi Zhang, Linda Chen, Alex B. Blair, Thatcher Heumann, Rose Parkinson, Jennifer N. Durham, Amol Narang, Robert A. Anders, Christopher L. Wolfgang, Daniel A. Laheru, Jin He, Arsen Osipov, Elizabeth D. Thompson, Hao Wang, Elana J. Fertig, Elizabeth M. Jaffee, Lei Zheng - Cancer Cell 2022 cited by 178
- Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer
Authors: Katelyn T. Byrne, Courtney B. Betts, Rosemarie Mick, Shamilene Sivagnanam, David L. Bajor, Daniel A. Laheru, E. Gabriela Chiorean, Mark H. O’Hara, Shannon M. Liudahl, Craig Newcomb, Cécile Alanio, Ana Paula Ferreira, Byung Park, Takuya Ohtani, Austin P. Huffman, Sara A. Väyrynen, Andressa Dias Costa, Judith C. Kaiser, Andreanne M. Lacroix, Colleen Redlinger, Martin Stern, Jonathan A. Nowak, E. John Wherry, Martin A. Cheever, Brian M. Wolpin, Emma E. Furth, Elizabeth M. Jaffee, Lisa M. Coussens, Robert H. Vonderheide - Clinical Cancer Research 2021 cited by 180
- Metastatic Pancreatic Cancer: ASCO Guideline Update
Authors: Davendra Sohal, Erin B. Kennedy, Pelin Cinar, Thierry Conroy, Mehmet Sitki Copur, Christopher H. Crane, Ignacio Garrido‐Laguna, Michelle Lau, Tyler Johnson, Smitha Krishnamurthi, Cassadie Moravek, Eileen M. O’Reilly, Philip A. Philip, Shubham Pant, Manish A. Shah, Vaibhav Sahai, Hope E. Uronis, Neeha Zaidi, Daniel A. Laheru - Journal of Clinical Oncology 2020 cited by 289
- A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma
Authors: Thatcher Heumann, Carol Judkins, Keyu Li, Su Jin Lim, Jessica Hoare, Rose Parkinson, Haihui Cao, Tengyi Zhang, Jessica Gai, Betul Celiker, Qingfeng Zhu, Thomas McPhaul, Jennifer N. Durham, Katrina Purtell, Rachel Klein, Daniel A. Laheru, Ana De Jesus‐Acosta, Dung T. Le, Amol Narang, Robert A. Anders, Richard A. Burkhart, William R. Burns, Kevin C. Soares, Christopher L. Wolfgang, Elizabeth D. Thompson, Elizabeth M. Jaffee, Hao Wang, Jin He, Lei Zheng - Nature Communications 2023 cited by 83
- Evaluation of Cyclophosphamide/GVAX Pancreas Followed by Listeria-Mesothelin (CRS-207) with or without Nivolumab in Patients with Pancreatic Cancer
Authors: Takahiro Tsujikawa, Todd S. Crocenzi, Jennifer N. Durham, Elizabeth A. Sugar, Annie A. Wu, Beth Onners, Julie M. Nauroth, Robert A. Anders, Elana J. Fertig, Daniel A. Laheru, Kim A. Reiss, Robert H. Vonderheide, Andrew H. Ko, Margaret A. Tempero, George A. Fisher, Michael Considine, Ludmila Danilova, Dirk G. Brockstedt, Lisa M. Coussens, Elizabeth M. Jaffee, Dung T. Le - Clinical Cancer Research 2020 cited by 152
- Evaluation of Ipilimumab in Combination With Allogeneic Pancreatic Tumor Cells Transfected With a GM-CSF Gene in Previously Treated Pancreatic Cancer
Authors: Dung T. Le, Eric R. Lutz, Jennifer N. Uram, Elizabeth A. Sugar, Beth Onners, Sara Solt, Lei Zheng, Luis A. Díaz, Ross C. Donehower, Elizabeth M. Jaffee, Daniel A. Laheru - Journal of Immunotherapy 2013 cited by 554
- A Phase II Study of Allogeneic GM-CSF–Transfected Pancreatic Tumor Vaccine (GVAX) with Ipilimumab as Maintenance Treatment for Metastatic Pancreatic Cancer
Authors: Annie A. Wu, Katherine M. Bever, Won Jin Ho, Elana J. Fertig, Nan Niu, Lei Zheng, Rose Parkinson, Jennifer N. Durham, Beth Onners, Anna Ferguson, Cara Wilt, Andrew H. Ko, Andrea Wang‐Gillam, Daniel A. Laheru, Robert A. Anders, Elizabeth D. Thompson, Elizabeth A. Sugar, Elizabeth M. Jaffee, Dung T. Le - Clinical Cancer Research 2020 cited by 127
- Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer
Authors: Thomas B. Karasic, Mark H. O’Hara, Arturo Loaiza‐Bonilla, Kim A. Reiss, Ursina Teitelbaum, Erkut Borazanci, Ana De Jesus‐Acosta, Colleen Redlinger, Jessica Burrell, Daniel A. Laheru, Daniel D. Von Hoff, Ravi K. Amaravadi, Jeffrey A. Drebin, Peter J. O’Dwyer - JAMA Oncology 2019 cited by 290
- Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma
Authors: Daniel Shu, Won Jin Ho, Luciane T. Kagohara, Alexander A. Girgis, Sarah M. Shin, Ludmila Danilova, Jae W. Lee, Dimitrios N. Sidiropoulos, Sarah Mitchell, Kabeer Munjal, Kathryn L. Howe, Kayla J. Bendinelli, Emma Kartalia, Hanfei Qi, Guanglan Mo, Janelle M. Montagne, James M. Leatherman, Tamara Y. Lopez-Vidal, Qingfeng Zhu, Amanda L. Huff, Xuan Yuan, Alexei Hernandez, Erin M. Coyne, Neeha Zaidi, Daniel J. Zabransky, Elizabeth L. Engle, Aleksandra Ogurtsova, Marina Baretti, Daniel A. Laheru, Jennifer N. Durham, Hao Wang, Joel Sunshine, Robert J. Johnston, Julie S. Deutsch, Janis M. Taube, Robert A. Anders, Elizabeth M. Jaffee, Elana J. Fertig, Mark Yarchoan - Nature Immunology 2024 cited by 89
- Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma
Authors: Ana De Jesus‐Acosta, Elizabeth A. Sugar, Peter J. O’Dwyer, Ramesh K. Ramanathan, Daniel D. Von Hoff, Zeshaan A. Rasheed, Lei Zheng, Asma Begum, Robert A. Anders, Anirban Maitra, Florencia McAllister, N.V. Rajeshkumar, Shinichi Yabuuchi, Roeland F. de Wilde, Bhavina Batukbhai, İsmet Şahin, Daniel A. Laheru - British Journal of Cancer 2019 cited by 170
- Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection
Authors: Georgios Gemenetzis, Vincent P. Groot, Alex B. Blair, Daniel A. Laheru, Lei Zheng, Amol Narang, Elliot K. Fishman, Ralph H. Hruban, Jun Yu, Richard A. Burkhart, John L. Cameron, Matthew J. Weiss, Christopher L. Wolfgang, Jin He - Annals of Surgery 2018 cited by 394
- PD-1/PD-L1 Blockade Together With Vaccine Therapy Facilitates Effector T-Cell Infiltration Into Pancreatic Tumors
Authors: Kevin C. Soares, Agnieszka A. Rucki, Annie A. Wu, Kelly Olino, Qian Xiao, Yi Chai, Anthony Wamwea, Elaine Bigelow, Eric R. Lutz, Linda Liu, Sheng Yao, Robert A. Anders, Daniel A. Laheru, Christopher L. Wolfgang, Barish H. Edil, Richard D. Schulick, Elizabeth M. Jaffee, Lei Zheng - Journal of Immunotherapy 2014 cited by 394
- A Live-Attenuated Listeria Vaccine (ANZ-100) and a Live-Attenuated Listeria Vaccine Expressing Mesothelin (CRS-207) for Advanced Cancers: Phase I Studies of Safety and Immune Induction
Authors: Dung T. Le, Dirk G. Brockstedt, Ran Nir‐Paz, Johannes Hampl, Shruti Mathur, John Nemunaitis, Daniel H. Sterman, Raffit Hassan, Eric R. Lutz, Bentley Moyer, Martin Giedlin, Jana-Lynn Louis, Elizabeth A. Sugar, Alice Pons, Andrea L. Cox, Jordana Levine, Aimee Murphy, Peter B. Illei, Thomas W. Dubensky, Joseph E. Eiden, Elizabeth M. Jaffee, Daniel A. Laheru - Clinical Cancer Research 2011 cited by 368
- Vaccine-Induced Intratumoral Lymphoid Aggregates Correlate with Survival Following Treatment with a Neoadjuvant and Adjuvant Vaccine in Patients with Resectable Pancreatic Adenocarcinoma
Authors: Lei Zheng, Ding Ding, Barish H. Edil, Carol Judkins, Jennifer N. Durham, Dwayne L. Thomas, Katherine M. Bever, Guanglan Mo, Sara Solt, Jessica Hoare, Raka Bhattacharya, Qingfeng Zhu, Arsen Osipov, Beth Onner, Katrina Purtell, Hongyan Cai, Rose Parkinson, Amy Hacker‐Prietz, Joseph M. Herman, Dung T. Le, Nilofer S. Azad, Ana De Jesus‐Acosta, Alex B. Blair, Victoria Kim, Kevin C. Soares, Lindsey Manos, John L. Cameron, Martin A. Makary, Matthew J. Weiss, Richard D. Schulick, Jin He, Christopher L. Wolfgang, Elizabeth D. Thompson, Robert A. Anders, Elizabeth A. Sugar, Elizabeth M. Jaffee, Daniel A. Laheru - Clinical Cancer Research 2020 cited by 77
- Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer
Authors: Vincent P. Groot, Stacy Mosier, Ammar A. Javed, Jonathan A. Teinor, Georgios Gemenetzis, Ding Ding, Lisa Haley, Jun Yu, Richard A. Burkhart, Alina Hasanain, Marija Debeljak, Hirohiko Kamiyama, Amol Narang, Daniel A. Laheru, Lei Zheng, Ming‐Tseh Lin, Christopher D. Gocke, Elliot K. Fishman, Ralph H. Hruban, Michael Goggins, I. Quintus Molenaar, John L. Cameron, Matthew J. Weiss, Victor E. Velculescu, Jin He, Christopher L. Wolfgang, James R. Eshleman - Clinical Cancer Research 2019 cited by 193
- Gemcitabine Plusnab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial
Authors: Daniel D. Von Hoff, Ramesh K. Ramanathan, Mitesh J. Borad, Daniel A. Laheru, Lon Smith, Tina E. Wood, Ronald L. Korn, Neil Desai, Vuong Trieu, J. L. Mesías Iglesias, Hui Zhang, Patrick Soon‐Shiong, Tao Shi, N.V. Rajeshkumar, Anirban Maitra, Manuel Hidalgo - Journal of Clinical Oncology 2011 cited by 1,045
- DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer
Authors: Christine A. Iacobuzio–Donahue, Baojin Fu, Shinichi Yachida, Mingde Luo, Hisashi Abe, Clark M. Henderson, F Vilardell, Zheng Wang, Jesse W. Keller, Priya R. Banerjee, Joseph M. Herman, John L. Cameron, Charles J. Yeo, Marc K. Halushka, James R. Eshleman, Marian Raben, Alison P. Klein, Ralph H. Hruban, Manuel Hidalgo, Daniel A. Laheru - Journal of Clinical Oncology 2009 cited by 1,078
