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William C. Skarnes

Active 1989–2026

77
Papers
18,269
Citations
61
h-index
70
i10-index

Citations

Citations per year for William C. Skarnes1988: 1 citations1989: 15 citations1990: 25 citations1991: 31 citations1992: 21 citations1993: 17 citations1994: 14 citations1995: 17 citations1996: 24 citations1997: 51 citations1998: 38 citations1999: 65 citations2000: 70 citations2001: 136 citations2002: 148 citations2003: 166 citations2004: 192 citations2005: 195 citations2006: 169 citations2007: 200 citations2008: 161 citations2009: 158 citations2010: 155 citations2011: 156 citations2012: 198 citations2013: 188 citations2014: 180 citations2015: 192 citations2016: 193 citations2017: 216 citations2018: 200 citations2019: 633 citations2020: 564 citations2021: 505 citations2022: 380 citations2023: 273 citations2024: 463 citations2025: 200 citations2026: 8 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,133 citing papers, 32.4% of this breakdownUnited Kingdom: 931 citing papers, 9.6% of this breakdownGermany: 724 citing papers, 7.5% of this breakdownChina: 607 citing papers, 6.3% of this breakdownFrance: 459 citing papers, 4.7% of this breakdownCanada: 433 citing papers, 4.5% of this breakdownJapan: 413 citing papers, 4.3% of this breakdownNetherlands: 298 citing papers, 3.1% of this breakdownAustralia: 244 citing papers, 2.5% of this breakdownItaly: 239 citing papers, 2.5% of this breakdownSpain: 210 citing papers, 2.2% of this breakdownSwitzerland: 207 citing papers, 2.1% of this breakdown
0%32.4%Other 18.3%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology63.8%
  • Medicine15.9%
  • Neuroscience14.6%
  • Immunology and Microbiology2.9%
  • Agricultural and Biological Sciences0.6%
  • Engineering0.4%
  • Other1.8%

Topics

  • CRISPR and Genetic Engineering5.2%
  • Axon Guidance and Neuronal Signaling3.6%
  • Pluripotent Stem Cells Research3.2%
  • Wnt/β-catenin signaling in development and cancer2.7%
  • Epigenetics and DNA Methylation2.4%
  • Neurogenesis and neuroplasticity mechanisms2.3%
  • Other80.6%

Coauthors

All papers

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  1. A reference human induced pluripotent stem cell line for large-scale collaborative studies

    Authors: Caroline B. Pantazis, Andrian Yang, Erika Lara, Justin A. McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kumar Kanaujiya, Jizhong Zou, David P. Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, Constance Medura, Christopher Tompkins, Stephen H. Hughes, Marianita Santiana, Faraz Faghri, Mike A. Nalls, Dan Vitale, Shannon Ballard, Yue Qi, Daniel M. Ramos, Kailyn Anderson, Julia T. Stadler, Priyanka Narayan, Jason Papademetriou, Luke Reilly, Matthew P. Nelson, Sanya Aggarwal, Leah U. Rosen, Peter Kirwan, Venkat Pisupati, Steven L. Coon, Sonja W. Scholz, Theresa Priebe, Miriam Öttl, Jian Dong, Marieke Meijer, Lara J.M. Janssen, Vanessa S. Lourenco, Rik van der Kant, Dennis Crusius, Dominik Paquet, Ana‐Caroline Raulin, Guojun Bu, Aaron Held, Brian J. Wainger, Rebecca Gabriele, Jackie M. Casey, Selina Wray, Dad Abu-Bonsrah, Clare L. Parish, Melinda S. Beccari, Don W. Cleveland, Emmy Li, Indigo V.L. Rose, Martin Kampmann, Carles Calatayud, Patrik Verstreken, Laurin Heinrich, Max Y. Chen, Birgitt Schüle, Dan Dou, Erika L.F. Holzbaur, Maria Clara Zanellati, Richa Basundra, Mohanish Deshmukh, Sarah Cohen, Richa Khanna, Malavika Raman, Zachary S. Nevin, Madeline Matia, Jonas Van Lent, Vincent Timmerman, Bruce R. Conklin, Katherine Johnson Chase, Ke Zhang, Salome Funes, Daryl A. Bosco, Lena Erlebach, Marc Welzer, Deborah Kronenberg‐Versteeg, Guochang Lyu, Ernest Arenas, Elena Coccia, Lily Sarrafha, Tim Ahfeldt, John C. Marioni, William C. Skarnes, Mark Cookson, Michael E. Ward, Florian T. Merkle - Cell stem cell 2022 cited by 304

  2. High-throughput discovery of novel developmental phenotypes

    Authors: Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret A. Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, M. Eileen Dolan, Sarah Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil Horner, Chih‐Wei Hsu, Sara Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M. J. Nutter, Kevin A. Peterson, Ramiro Ramírez‐Solis, Douglas J. Rowland, Edward J. Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, Wolfgang Wurst, Daniel G. MacArthur, Glauco P. Tocchini‐Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen Parkinson, Mark W. Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabě de Angelis, Yann Hérault, Tim Mohun, Ann‐Marie Mallon, R. Mark Henkelman, Steve D. M. Brown, David J. Adams, K. C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bućan, Stephen A. Murray - Nature 2016 cited by 1,307

  3. A conditional knockout resource for the genome-wide study of mouse gene function

    Authors: William C. Skarnes, Barry P. Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David K. Jackson, Jessica Severin, Patrick J. Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley - Nature 2011 cited by 1,839

  4. Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

    Authors: Bin Shen, Wensheng Zhang, Jun Zhang, Jiankui Zhou, Jian-Ying Wang, Li Chen, Lu Wang, Alex Hodgkins, Vivek Iyer, Xingxu Huang, William C. Skarnes - Nature Methods 2014 cited by 838

  5. Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway

    Authors: Yen‐Chen Lin, Meenakshi Sundaram Kumar, Nandini Ramesh, Eric N. Anderson, Aivi T. Nguyen, Boram Kim, Simon Cheung, Justin A. McDonough, William C. Skarnes, Rodrigo Lopez-Gonzalez, John E. Landers, Nicolas L. Fawzi, Ian R. Mackenzie, Edward B. Lee, Jeffrey A. Nickerson, David Grünwald, Udai Bhan Pandey, Daryl A. Bosco - Nature Neuroscience 2021 cited by 100

  6. Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH

    Authors: Daniel M. Ramos, William C. Skarnes, Andrew Singleton, Mark Cookson, Michael E. Ward - Neuron 2021 cited by 106

  7. Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

    Authors: Tito Serafini, Sophia A. Colamarino, E. David Leonardo, Hao Wang, Rosa Beddington, William C. Skarnes, Marc Tessier‐Lavigne - Cell 1996 cited by 1,288

  8. An LDL-receptor-related protein mediates Wnt signalling in mice

    Authors: Kathleen I. Pinson, Jane Brennan, Susan J. Monkley, Brian J. Avery, William C. Skarnes - Nature 2000 cited by 1,086

  9. Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

    Authors: Jacqueline K. White, Anna-Karin Gerdin, Natasha A. Karp, Edward J. Ryder, Marija Buljan, James Bussell, Jennifer Salisbury, Simon Clare, Neil J. Ingham, Christine Podrini, Richard Houghton, Jeanne Estabel, Joanna Bottomley, David Melvin, David Sunter, Niels C. Adams, David Tannahill, Darren W. Logan, Daniel G. MacArthur, Jonathan Flint, Vinit B. Mahajan, Stephen H. Tsang, Ian Smyth, Fiona M. Watt, William C. Skarnes, Gordon Dougan, David J. Adams, Ramiro Ramírez‐Solis, Allan Bradley, Karen P. Steel, Lauren Baker, Caroline Barnes, Ryan M. Beveridge, Emma L. Cambridge, Damian M. Carragher, Prabhjoat Chana, Kay Clarke, Yvette Hooks, Natalia Igosheva, Ozama Ismail, Hannah Jackson, Leanne Kane, Rosalind Lacey, David Lafont, Mark Lucas, Simon Maguire, Katherine McGill, Rebecca E. McIntyre, Sophie Messager, Lynda Mottram, Lee Mulderrig, Selina Pearson, Hayley Protheroe, Laura-Anne Roberson, Grace Salsbury, Mark Sanderson, Daniel Sanger, Carl Shannon, Paul C. Thompson, Elizabeth Tuck, Valerie E. Vancollie, Lisa Brackenbury, Wendy Bushell, Ross Cook, Priya Dalvi, Diane Gleeson, Bishoy Habib, Matt Hardy, Kifayathullah Liakath‐Ali, Evelina Miklejewska, Stacey Price, Debarati Sethi, Elizabeth Trenchard, Dominique Von Schiller, Sapna Vyas, Anthony P. West, John R. Woodward, Elizabeth Wynn, Arthur Evans, David Gannon, Mark Griffiths, S. Holroyd, Vivek Iyer, Christian Kipp, Morag A. Lewis, Wei Li, Darren Oakley, David Richardson, Damian Smedley, Chukwuma A. Agu, Jackie Bryant, Liz Delaney, Nadia I. Gueorguieva, Helen Tharagonnet, Anne J. Townsend, Daniel Biggs, Ellen Brown, Adam Collinson, Charles-Étienne Dumeau, Evelyn Grau and 30 more - Cell 2013 cited by 547

  10. Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

    Authors: Terrence F. Meehan, Nathalie Conte, David B. West, Julius O.B. Jacobsen, Jeremy Mason, Jonathan Warren, Chao-Kung Chen, Ilinca Tudose, Mike Relac, Peter Matthews, Natasha A. Karp, Luís Santos, Tanja Fiegel, Natalie Ring, Henrik Westerberg, Simon Greenaway, Duncan Sneddon, Hugh W. Morgan, Gemma Codner, Michelle Stewart, James M. Brown, Neil Horner, Melissa Haendel, Nicole Washington, Chris Mungall, Corey Reynolds, Juan Gallegos, Valérie Gailus‐Durner, Tania Sorg, Guillaume Pavlovic, Lynette R Bower, Mark W. Moore, Iva Morse, Xiang Gao, Glauco P. Tocchini‐Valentini, Yuichi Obata, Soo Young Cho, Je Kyung Seong, John Seavitt, Arthur L. Beaudet, Mary E. Dickinson, Yann Hérault, Wolfgang Wurst, Martin Hrabě de Angelis, K. C. Kent Lloyd, Ann M. Flenniken, Lauryl M. J. Nutter, Susan Newbigging, Colin McKerlie, Monica J. Justice, Stephen A. Murray, Karen L. Svenson, Robert E. Braun, Jacqueline K. White, Allan Bradley, Paul Flicek, Sara Wells, William C. Skarnes, David J. Adams, Helen Parkinson, Ann‐Marie Mallon, Steve D M Brown, Damian Smedley - Nature Genetics 2017 cited by 268

  11. Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice

    Authors: Jingliang Zhang, Xiaoling Chen, Muriel Eaton, Jiaxiang Wu, Zhixiong Ma, Shirong Lai, Anthony Park, Talha S. Ahmad, Zhefu Que, Ji Hea Lee, Tiange Xiao, Yuansong Li, Yujia Wang, Maria I. Olivero-Acosta, James A. Schaber, Krishna Jayant, Chongli Yuan, Zhuo Huang, Nadia A. Lanman, William C. Skarnes, Yang Yang - Cell Reports 2021 cited by 126

  12. A resource of targeted mutant mouse lines for 5,061 genes

    Authors: Marie‐Christine Birling, Atsushi Yoshiki, David J. Adams, Shinya Ayabe, Arthur L. Beaudet, Joanna Bottomley, Allan Bradley, Steve D. M. Brown, Antje Bürger, Wendy Bushell, Francesco Chiani, Hsian‐Jean Chin, Skevoulla Christou, Gemma Codner, Francesco J. DeMayo, Mary E. Dickinson, Brendan Doe, Leah Rae Donahue, Martin Fray, Alessia Gambadoro, Xiang Gao, Marina Gertsenstein, Alba Gomez-Segura, Leslie O. Goodwin, Jason D. Heaney, Yann Hérault, Martin Hrabě de Angelis, Si‐Tse Jiang, Monica J. Justice, Petr Kašpárek, Ruairidh King, Ralf Kühn, Ho Lee, Young Jae Lee, Zhiwei Liu, K. C. Kent Lloyd, Isabel Lorenzo, Ann‐Marie Mallon, Colin McKerlie, Terrence F. Meehan, Violeta Muñoz‐Fuentes, Stuart Newman, Lauryl M. J. Nutter, Goo Taeg Oh, Guillaume Pavlovic, Ramiro Ramírez‐Solis, Barry P. Rosen, Edward J. Ryder, Luís Santos, Joel Schick, John R. Seavitt, Radislav Sedláček, Claudia Seisenberger, Je Kyung Seong, William C. Skarnes, Tania Sorg, Karen P. Steel, Masaru Tamura, Glauco P. Tocchini‐Valentini, Chi‐Kuang Leo Wang, Hannah Wardle‐Jones, Marie Wattenhofer‐Donzé, Sara Wells, Michael V. Wiles, Brandon Willis, Joshua A. Wood, Wolfgang Wurst, Ying Xu, Juan Gallegos, Jennie R. Green, Ritu Bohat, Katie Zimmel, Monica Pereira, S. MacMaster, Sandra Tondat, Linda Wei, Tracy Carroll, Jorge Cabezas, Qing Fan-Lan, Elsa Jacob, Amie Creighton, Patricia Castellanos-Penton, Ozge Danisment, Shannon Clarke, Joanna Joeng, Deborah F. Kelly, Christine To, Rebekah van Bruggen, Valerie Gailus-Durner, Helmut Fuchs, Susan Marschall, Stefanie Dunst, Markus Romberger, Bernhard Rey, Sabine Fessele, Philipp Gormanns, Roland H. Friedel, Cornelia Kaloff, Andreas Hörlein, Sandy Teichmann and 125 more - Nature Genetics 2021 cited by 114

  13. WGE: a CRISPR database for genome engineering

    Authors: Alex Hodgkins, Anna Farne, Sajith Perera, Tiago Grego, David J. Parry-Smith, William C. Skarnes, Vivek Iyer - Bioinformatics, Bioinform. 2015 cited by 223

  14. Agouti C57BL/6N embryonic stem cells for mouse genetic resources

    Authors: Stephen J. Pettitt, Qi Liang, Xin Y. Rairdan, Jennifer L. Moran, Haydn M. Prosser, David R. Beier, K. C. Kent Lloyd, Allan Bradley, William C. Skarnes - Nature Methods 2009 cited by 399

  15. The mammalian gene function resource: the international knockout mouse consortium

    Authors: Allan Bradley, Konstantinos Anastassiadis, A. Ayadi, James F. Battey, Cindy Bell, Marie‐Christine Birling, Joanna Bottomley, Steve D. M. Brown, Antje Bürger, Carol J. Bult, Wendy Bushell, Francis S. Collins, Christian Desaintes, Brendan Doe, Aris N. Economides, Janan T. Eppig, Richard H. Finnell, Colin Fletcher, Martin Fray, David Frendewey, Roland H. Friedel, Frank Grosveld, Jens Hansen, Yann Hérault, Geoffrey G. Hicks, Andreas Hörlein, Richard Houghton, Martin Hrabě de Angelis, Danny Huylebroeck, Vivek Iyer, Pieter J. de Jong, James A. Kadin, Cornelia Kaloff, Karen L. Kennedy, Manousos Koutsourakis, K. C. Kent Lloyd, Susan Marschall, Jeremy Mason, Colin McKerlie, Michael P. McLeod, Harald von Melchner, Mark W. Moore, Alejandro O. Mujica, András Nagy, Mikhail Nefedov, Lauryl M. J. Nutter, Guillaume Pavlovic, Jane L. Peterson, Jonathan D. Pollock, Ramiro Ramírez‐Solis, Derrick E. Rancourt, Marcello Raspa, Jacques Remacle, Martin Ringwald, Barry P. Rosen, Nadia Rosenthal, Janet Rossant, Patricia Ruíz, Edward J. Ryder, Joel Schick, Frank Schnütgen, Paul N. Schofield, Claudia Seisenberger, Mohammed Selloum, Elizabeth M. Simpson, William C. Skarnes, Damian Smedley, William L. Stanford, A. Francis Stewart, Kevin Stone, Kate Swan, Hamsa D. Tadepally, Lydia Teboul, Glauco P. Tocchini‐Valentini, David M. Valenzuela, Anthony P. West, Ken‐ichi Yamamura, Yuko Yoshinaga, Wolfgang Wurst - Mammalian Genome 2012 cited by 328

  16. Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform

    Authors: Chris Denning, Viola Borgdorff, James Crutchley, Karl Firth, Vinoj George, Spandan Kalra, Alexander Kondrashov, Minh Duc Hoang, Diogo Mosqueira, Asha K. Patel, Ljupcho Prodanov, Divya Rajamohan, William C. Skarnes, James G.W. Smith, Lorraine Young - Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2015 cited by 294

  17. Improving homology-directed repair efficiency in human stem cells

    Authors: William C. Skarnes, Enrica Pellegrino, Justin A. McDonough - Methods 2019 cited by 113

  18. Generation and basic characterization of a gene‐trap knockout mouse model of Scn2a with a substantial reduction of voltage‐gated sodium channel Nav1.2 expression

    Authors: Muriel Eaton, Jingliang Zhang, Zhixiong Ma, Anthony C. Park, Emma E Lietzke, Chloé Maricela Romero, Yushuang Liu, Emily Rose Coleman, Xiaoling Chen, Tiange Xiao, Zhefu Que, Shirong Lai, Jiaxiang Wu, Ji Hea Lee, Sophia Palant, Huynhvi P. Nguyen, Zhuo Huang, William C. Skarnes, Wendy A. Koss, Yang Yang - Genes Brain & Behavior 2020 cited by 40

  19. Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse

    Authors: Paula A. Coelho, Leah Bury, Marta N. Shahbazi, Kifayathullah Liakath‐Ali, Peri Tate, Sam Wormald, Christopher J. Hindley, Meritxell Huch, Joy Archer, William C. Skarnes, Magdalena Zernicka‐Goetz, David M. Glover - Open Biology 2015 cited by 171

  20. ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a

    Authors: Xiaolin Gao, Peri Tate, Ping Hu, Robert Tjian, William C. Skarnes, Zhong Wang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 347

  21. Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2

    Authors: Subhankar Mukhopadhyay, Eva Heinz, Immacolata Porreca, Kaur Alasoo, Amy Yeung, Huei-Ting Yang, Tobias Schwerd, Jessica L. Forbester, Christine Hale, Chukwuma A. Agu, Yoon Ha Choi, Julia Rodrigues, Melania Capitani, Luke Jostins-Dean, David Thomas, Simon Travis, Daniel J. Gaffney, William C. Skarnes, Nicholas R. Thomson, Holm H. Uhlig, Gordon Dougan, Fiona Powrie - The Journal of Experimental Medicine 2019 cited by 70

  22. Endoplasmic Reticulum Stress Induction of the Grp78/BiP Promoter: Activating Mechanisms Mediated by YY1 and Its Interactive Chromatin Modifiers

    Authors: Peter Baumeister, Shengzhan Luo, William C. Skarnes, Guangchao Sui, Edward Seto, Yang Shi, Amy S. Lee - Molecular and Cellular Biology 2005 cited by 222

  23. ATP-Citrate Lyase Deficiency in the Mouse

    Authors: Anne P. Beigneux, Cynthia Kosinski, Bryant J. Gavino, Jay D. Horton, William C. Skarnes, Stephen G. Young - Journal of Biological Chemistry 2004 cited by 152

  24. Defining the Importance of Phosphatidylserine Synthase 2 in Mice

    Authors: Martin O. Bergö, Bryant J. Gavino, Renske D.M. Steenbergen, Bénédicte Sturbois, Albert F. Parlow, David A. Sanan, William C. Skarnes, Jean E. Vance, Stephen G. Young - Journal of Biological Chemistry 2002 cited by 100